Reverse translational analysis of clinically reported, lamotrigine-induced cardiovascular adverse events using the halothane-anesthetized dogs.

abstract：:Previous studies have reported the prognostic value of objective nutritional indices such as the Controlling Nutritional Status (CONUT) score, Geriatric Nutritional Risk Index (GNRI) and Prognostic Nutritional Index (PNI). However, the effects of these indices in patients with coronary artery disease (CAD) who have un...

journal_title：Heart and vessels

authors： Wada H,Dohi T,Miyauchi K,Endo H,Tsuboi S,Ogita M,Kasai T,Okazaki S,Isoda K,Suwa S,Daida H

更新日期：2018-12-01 00:00:00

abstract：:The possibility of minimizing organ damage following cardiopulmonary bypass (CPB) was examined. In the control group, n = 21, upon completion of CPB, elevation of the lysosomal enzyme beta-glucuronidase, which is a sensitive indicator of cellular damage, was affected by the concentration of granulocyte elastase (r = 0...

journal_title：Heart and vessels

authors： Hashimoto K,Nomura K,Nakano M,Sasaki T,Kurosawa H

更新日期：1993-01-01 00:00:00

abstract：:Renin-angiotensin system (RAS) inhibitors may be useful in preventing the occurrence of paroxysmal atrial fibrillation (PAF). However, evaluation of such effect is difficult because many PAF episodes are asymptomatic and not all episodes are detected by intermittent electrocardiographic monitoring. A pacemaker has bee...

journal_title：Heart and vessels

authors： Takii E,Inage T,Yoshida T,Ohe M,Gondo T,Haraguchi G,Ito S,Kumanomido J,Imaizumi T,Fukuomoto Y

更新日期：2016-03-01 00:00:00

abstract：:Although the suction force that moves blood into the left ventricle during early diastole is thought to play an important role in diastolic function, there have been a few studies of this phenomenon in normal children. Suction force is measured as the intraventricular pressure difference (IVPD) and intraventricular pr...

journal_title：Heart and vessels

authors： Takahashi K,Nii M,Takigiku K,Toyono M,Iwashima S,Inoue N,Tanaka N,Matsui K,Shigemitsu S,Yamada M,Kobayashi M,Yazaki K,Itatani K,Shimizu T

更新日期：2019-02-01 00:00:00

abstract：:In order to clarify the pathogenesis of acute myocardial infarction (MI) in hearts with normal coronary arteries, infarct size, and the extent of contraction band necrosis (CBN), coagulation necrosis, and hemorrhage were quantitatively examined using an image analyzer in 5 autopsy cases of MI with normal or nearly nor...

journal_title：Heart and vessels

authors： Wu DJ,Fujiwara H,Matsuda M,Ishida M,Kawamura A,Takemura G,Kida M,Uegaito T,Fujiwara T,Kawai C

更新日期：1990-01-01 00:00:00

abstract：:Coexistence of hypertension and diabetes mellitus (DM) increases the risk of cardiovascular disease. However, factors associated with future development of DM have not been well elucidated in patients already having essential hypertension. This study prospectively included 168 patients (mean age 41 +/- 7 years, 112 me...

journal_title：Heart and vessels

authors： Weng CM,Chou CH,Huang YY,Lin CC,Liu YW,Tsai WC

更新日期：2010-09-01 00:00:00

abstract：:The primary study aim was to determine whether ischemia-modified albumin (IMA) predicts adverse outcome in patients attending the emergency department (ED) with acute chest pain. Ischemia-modified albumin is a sensitive marker of myocardial ischemia. However, little is known about its ability to predict outcome in pat...

journal_title：Heart and vessels

authors： Consuegra-Sanchez L,Bouzas-Mosquera A,Sinha MK,Collinson PO,Gaze DC,Kaski JC

更新日期：2008-05-01 00:00:00

abstract：:The aim of the study was to evaluate systemic right ventricular (RV) dyssynchrony in patients with congenitally corrected transposition of the great arteries (CCTGA) and transposition of the great arteries (TGA) with New York Heart Association functional class (NYHA FC) < III. We used cardiac magnetic resonance (CMR) ...

journal_title：Heart and vessels

authors： Shiina Y,Inai K,Takahashi T,Taniguchi K,Watanabe E,Fukushima K,Niwa K,Nagao M

更新日期：2018-09-01 00:00:00

abstract：:The effect of intravenous enoximone on forearm venous circulation was studied in ten healthy volunteers (group A) and in ten patients with NYHA class III-IV congestive heart failure (group B). Distensibility of the forearm capacitance vessels was assessed from pressure-volume curves by venous occlusion plethysmography...

journal_title：Heart and vessels

authors： Branzi A,Berardi C,Ferretti RM,Beato E,Magnani G,Melandri G,Zannoli R,Magnani B

更新日期：1987-01-01 00:00:00

abstract：:Although endothelial progenitor cells (EPCs) are considered to be an essential source of vascular endothelial repair, their bidirectional differentiation determines that they play a double-edged role in the restoration of endothelial injury. In this research, we investigated the effect of Kir2.1 ion channel on the tra...

journal_title：Heart and vessels

authors： Li J,He Y,Bu H,Wang M,Yu J,Li L,Li H,Zhang X,Cui X,Cheng M

更新日期：2020-10-01 00:00:00

abstract：:This study investigates the interactions between cyclooxygenase (COX-2) and vascular smooth muscle cell (VSMC) phenotypic switching, the two important coupling mechanisms of the vasculature on arterial remodeling in response to high laminal shear stress. High aortic blood flow was induced by creating a fistula in the ...

journal_title：Heart and vessels

authors： Roan JN,Tsai YC,Chen IW,Chang SW,Huang CC,Lam CF

更新日期：2012-05-01 00:00:00

abstract：:Periprocedural bleeding and thromboembolic events are worrisome complications of catheter ablation for atrial fibrillation (AF). Periprocedural anticoagulation management could decrease the risk of these complications. However, evaluation of the complications from pulmonary vein isolation using cryoballoon related to ...

journal_title：Heart and vessels

authors： Ando M,Inden Y,Yoshida Y,Sairaku A,Yanagisawa S,Suzuki H,Watanabe R,Takenaka M,Maeda M,Murohara T

更新日期：2019-09-01 00:00:00

abstract：:We have theoretically proposed "systolic pressure-volume area" (PVA) as a measure of total mechanical energy generated by ventricular contraction. We then experimentally showed that PVA closely correlates with left ventricular oxygen consumption (Vo2) regardless of ventricular loading conditions in a stable contractil...

journal_title：Heart and vessels

authors： Suga H,Goto Y,Futaki S,Kawaguchi O,Yaku H,Hata K,Takasago T

更新日期：1991-01-01 00:00:00

abstract：:Increases in regional myocardial blood flow (Qm) developing soon after myocardial infarction may minimize myocardial necrosis. To test this hypothesis, Qm in the area surrounding an acutely occluded coronary artery was determined successively over 4 weeks in 11 dogs. Non-radioactive colored microspheres were injected ...

journal_title：Heart and vessels

authors： Nakai S,Ishikawa K,Ogawa I,Koka H,Kamata N,Akiyama H,Katori R

更新日期：1995-01-01 00:00:00

abstract：:In early systole, before the effects of reflected waves from the periphery become significant, the following equation applies: PA - PO = rho cu (1) where PA and PO are the instantaneous and end-diastolic pressures in the ascending aorta, rho the density of blood, c the velocity of the pulse wave in the aorta, and u th...

journal_title：Heart and vessels

authors： Harada Y,Sugawara M,Beppu T,Higashidate M,Nakata S,Imai Y

更新日期：1987-01-01 00:00:00

abstract：:Coronary artery spasm is involved in the pathogenesis of various cardiac disorders. We investigated patients with a history of syncope who underwent elective coronary angiography. We retrospectively analyzed 5781 consecutive patients who had diagnostic or follow-up angiography during a 26-year period. During this peri...

journal_title：Heart and vessels

authors： Sueda S,Kohno H

更新日期：2018-02-01 00:00:00

abstract：:It has been shown that green tea catechins (GTC) suppress proliferation of vascular smooth muscle cells (VSMCs) and that epigallocatechin-3-gallate (EGCG), which is a major constituent of GTC, selectively inhibits the platelet-derived growth factor-BB (PDGF-BB)-induced intracellular signaling transduction pathway. Vas...

journal_title：Heart and vessels

authors： Kim DW,Park YS,Kim YG,Piao H,Kwon JS,Hwang KK,Youn TJ,Park JB,Yun YP,Sachinidis A,Kim CH,Cho MC,Ahn HY

更新日期：2004-09-01 00:00:00

abstract：:Complex congenital heart diseases with abnormal formation of the aorticopulmonary septum are also associated with defective large artery elastogenesis. In the current study, we tested the hypothesis that carotid artery elastic function was impaired in patients with tetralogy of Fallot (ToF). The study included 45 Fall...

journal_title：Heart and vessels

authors： László A,Pintér A,Horváth T,Kádár K,Temesvári A,Kollai M,Studinger P

更新日期：2011-09-01 00:00:00

abstract：:MicroRNAs (miRNAs) are short non-coding RNAs that regulate gene expression. It seems that microRNA-21 (miR-21) and Visfatin, a novel adipocytokine, play roles in inflammation and atherosclerosis. The aim of this study was to investigate the association of miR-21 with Visfatin, inflammation, atherosclerosis and acute c...

journal_title：Heart and vessels

authors： Darabi F,Aghaei M,Movahedian A,Elahifar A,Pourmoghadas A,Sarrafzadegan N

更新日期：2017-05-01 00:00:00

abstract：:Mechanical alternans (MA) is frequently observed in patients with heart failure, and is a predictor of cardiac events. However, there have been controversies regarding the conditions and mechanisms of MA. To clarify heart rate-dependent contractile properties related to MA, we performed incremental right atrial pacing...

journal_title：Heart and vessels

authors： Kashimura T,Kodama M,Tanaka K,Sonoda K,Watanabe S,Ohno Y,Tomita M,Obata H,Mitsuma W,Ito M,Hirono S,Hanawa H,Aizawa Y

更新日期：2013-05-01 00:00:00

abstract：:Activation of mineralocorticoid receptor antagonists (MRAs) is cardioprotective; however, this property is lost upon blockade or inactivation of adenosine (ADO) receptor A2b. In this study, we investigated whether the effects of MRAs are mediated by an interaction between cardioprotective ADO receptors A1 and A3. Spir...

journal_title：Heart and vessels

authors： Hermidorff MM,de Assis LVM,Rodrigues JA,Soares LL,Andrade MHG,Natali AJ,Isoldi MC

更新日期：2020-05-01 00:00:00

abstract：:Cardiac systolic (left ventricular ejection fraction) and diastolic (mitral inflow velocity pattern and/or mitral deceleration time) function were reported as predictors of clinical outcome or left ventricular remodeling in patients with acute myocardial infarction (AMI). Recently, a new index (Doppler-derived index c...

journal_title：Heart and vessels

authors： Sasao H,Noda R,Hasegawa T,Endo A,Oimatsu H,Takada T

更新日期：2004-03-01 00:00:00

abstract：:Hydrogen peroxide (H2O2) elicited concentration-dependent relaxation of endothelium-denuded rings of porcine coronary arteries. The relaxation induced by the H2O2 was markedly attenuated by 10 microM 1H-[1,2,4]oxadiazolo [4,3,a]quinoxalin-1-one (ODQ), an inhibitor of soluble guanylate cyclase, or by 100 nM charybdotox...

journal_title：Heart and vessels

authors： Hayabuchi Y,Nakaya Y,Matsuoka S,Kuroda Y

更新日期：1998-01-01 00:00:00

abstract：:Raising high-density lipoprotein cholesterol (HDL-C) is an important strategy for reducing residual cardiovascular risk. In the present study, we sought to assess the effect of extended-release niacin/laropiprant on endothelial function in patients after a myocardial infarction with target low-density lipoprotein chol...

journal_title：Heart and vessels

authors： Bregar U,Jug B,Keber I,Cevc M,Sebestjen M

更新日期：2014-05-01 00:00:00

abstract：:This study was designed to investigate the effect of low-dose nesiritide on renal function and major cardiac events in patients with acute decompensated heart failure following acute myocardial infarction. Sixty patients were randomized into nesiritide (loading dose 0.5 microg/kg, maintenance dose 0.0075 microg/kg/min...

journal_title：Heart and vessels

authors： Zhao Q,Wu TG,Lin Y,Li B,Luo JY,Wang LX

更新日期：2010-03-01 00:00:00

abstract：:Treatment with inhibitors of 3-hydroxyl-3-methylglutaryl coenzyme A reductase (statins) reduces the incidence of cardiovascular events, but it is unclear whether the beneficial effects are mediated solely by their lipid-lowering properties. We therefore investigated whether atorvastatin reduces inflammation and oxidat...

journal_title：Heart and vessels

authors： Sugiyama M,Ohashi M,Takase H,Sato K,Ueda R,Dohi Y

更新日期：2005-07-01 00:00:00

abstract：:The vascular endothelial growth factor (VEGF) family of peptides and caveolins (CAVs) are reported to contribute, in early graft failure in patients, a coronary artery bypass grafting (CABG). To investigate the possible association of ultimate luminal occlusion to VEGFs and CAVs expression, a functional analysis (base...

journal_title：Heart and vessels

authors： Podemska-Jedrzejczak Z,Malinska A,Sujka-Kordowska P,Nowicki M,Puslecki M,Jemielity M,Perek B

更新日期：2018-09-01 00:00:00

abstract：:A 65-year-old man was admitted with chest pain. A diagnosis of spastic angina was made because of symptoms of recurrent anginal attacks associated with ST-segment elevations in the electrocardiogram. A selective coronary arteriogram revealed a 90% diameter narrowing of the proximal left anterior descending coronary ar...

journal_title：Heart and vessels

authors： Kusachi S,Takata S,Iwasaki K,Nishiyama O,Kita T,Namba H,Hata T,Taniguchi G,Saito D,Haraoka S

更新日期：1989-01-01 00:00:00

abstract：:Aortic dissection is a life-threatening cardiovascular disease with high in-hospital mortality. However, the risk factors of aortic dissection have not been fully elucidated. Obstructive sleep apnea (OSA) has been increasingly recognized as an independent cardiovascular risk factor. Among the underlying mechanisms to ...

journal_title：Heart and vessels

authors： Naito R,Sakakura K,Kasai T,Dohi T,Wada H,Sugawara Y,Kubo N,Yamashita S,Narui K,Ishiwata S,Ohno M,Ako J,Momomura S

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Predictors of left ventricular ejection fraction (LVEF) improvement after transcatheter aortic valve replacement (TAVR) in patients with a preoperative reduced LVEF are limited. OBJECTIVES:This study aimed to investigate the relationship between preprocedural valuvuloarterial impedance (ZVa), which represen...

journal_title：Heart and vessels

authors： Komatsu I,Hart C,Lau J,Spies C

更新日期：2020-09-01 00:00:00