Abstract：
:Several studies have demonstrated that nicotine (NIC) exhibits antidepressant-like effects. In addition, it has been suggested that sexual hormones participate in the antidepressant actions of antidepressives. The present study was designed to analyze the effect of orchiectomy and the supplementation of testosterone propionate (TP) or 17β-estradiol (E(2)) on the antidepressant properties of NIC using the forced swimming test (FST), as well as to determine possible changes in the FST during different time periods after orchiectomy. In order to evaluate the influences of orchiectomy on the effects of NIC, the study first evaluated the effects of different time periods on orchiectomized rats (15, 21, 30, 45 and 60 days) that were subjected to the FST. Then, different doses of NIC (0.2, 0.4, 0.8, 1.6 mg/kg, sc) were administered for 14 days to both intact and orchiectomized rats (after 21 day) which were then also subjected to the FST. Finally, the influence of the TP or E(2) supplementation on the antidepressant-like effect of NIC on orchiectomized rats (after 21 days) was also analyzed. Results reveal that orchiectomy significantly increased immobility behavior and decreased swimming and climbing up to 60 days after castration. In contrast, NIC decreased immobility behavior and increased swimming in intact rats; whereas orchiectomy suppressed this antidepressant effect of NIC. Only with E(2) supplementation was it possible to restore the sensitivity of the castrated rats to NIC. These results suggest that E(2) was able to facilitate the antidepressant response of NIC in orchiectomized rats.
journal_name
Physiol Behavjournal_title
Physiology & behaviorauthors
Bonilla-Jaime H,Limón-Morales O,Arteaga-Silva M,Hernández-González M,Guadarrama-Cruz G,Alarcón-Aguilar F,Vázquez-Palacios Gdoi
10.1016/j.physbeh.2010.07.011subject
Has Abstractpub_date
2010-11-02 00:00:00pages
456-61issue
4eissn
0031-9384issn
1873-507Xpii
S0031-9384(10)00276-3journal_volume
101pub_type
杂志文章abstract：:The current study examines the effects of electrolytic median raphe lesions on the feeding and drinking behaviors of rats maintained on a 23-hr food deprivation schedule. Measurement of food intake during the feeding period indicated no difference between the two groups but lesioned animals showed significantly more s...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(82)90108-1
更新日期：1982-01-01 00:00:00
abstract：:Thermal tasting, an important type of individual variation in orosensation, is a phenomenon by which some individuals perceive thermally-induced taste sensations simply by having the tip of their tongue warmed or cooled. These individuals, known as thermal tasters, report a variety of thermally-elicited tastes (typica...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2020.113160
更新日期：2020-12-01 00:00:00
abstract：:Food insecurity is a key indicator of well-being. This article provides an overview of food security measurement and population trends with a focus on adults with disabilities and their risk for food insecurity. Food-insecure households had difficulty providing enough food for all their members due to a lack of resour...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2020.112865
更新日期：2020-06-01 00:00:00
abstract：:Female OF1 mice aged 17-18 months were compared with female OF1 mice aged 7-11 weeks for locomotor activity, pain sensitivity, and cognitive performance using the Morris water maze, passive and active avoidance, and the elevated plus-maze learning protocol. Performance of old mice was impaired compared to those of you...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(99)00003-7
更新日期：1999-06-01 00:00:00
abstract：:Cancer patients frequently suffer from fatigue, a complex syndrome associated with tiredness and depressed mood. Cancer-related fatigue (CRF) can be present at the time of diagnosis, escalates during treatment, and can persist for years after treatment. CRF negatively influences quality of life, limits functional inde...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2014.12.045
更新日期：2015-03-01 00:00:00
abstract：:There is some evidence suggesting that stress may induce diabetes mellitus; the effects of restraint stress however need to be investigated. The present study investigates the role of chronic restraint stress on carbohydrate metabolism in male rats. The animals of the stressed group (n=8) were exposed to different res...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2006.06.023
更新日期：2006-10-30 00:00:00
abstract：:It has been demonstrated that the ventromedial hypothalamus (VMH) of alloxan-induced diabetic mice is protected from subsequent gold thioglucose (GTG)-induced lesions. Another compound, 3,3'-methyliminobis-(N-methylpropylamine) (MIMPA), a triamine structurally unrelated to GTG, has been shown to cause similar VMH lesi...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(91)90227-f
更新日期：1991-01-01 00:00:00
abstract：:Injection of clonidine or methyldopa in rats immediately after daily two-hour exposure to a complex environment (EC) reduced the increase in occipital cortical weight normally associated with such exposure in comparison with animals kept in isolation. Drug injection four hours after EC exposure had no effect. Drug ind...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(83)90053-7
更新日期：1983-01-01 00:00:00
abstract：:Communal nesting (CN) is a mouse model of early social enrichment during pregnancy and lactation. In this study, a rat model of CN was developed to determine if CN exerts an epigenetic effect in rats selectively bred for an infantile affective trait (high and low rates of ultrasonic distress calls). High and Low offsp...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2014.11.007
更新日期：2015-02-01 00:00:00
abstract：:Anodal direct currents of 1 or 10 microA were unilaterally applied for 30 min once a day to the premotor area of the cerebral cortex in rabbits, in which the current application was repeated 10 times at intervals of 2-3 days. Peripheral motor behavior was observed during and after each polarization trial, and was comp...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(92)90482-h
更新日期：1992-12-01 00:00:00
abstract：:The vigilance reaction is characterized by a large bradycardia, a pressor response, and inspiratory apnea in anesthetized rabbits and the inhibition of movement in conscious rabbits. This affective response pattern can be elicited by electrical stimulation of the dorsolateral hypothalamus (the hypothalamic vigilance a...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(97)00004-8
更新日期：1997-09-01 00:00:00
abstract：:Spawning behavior of H. fossilis was studied by breeding the fish in laboratory through hypophysation using pituitary glands of the Indian major carps (Catla catla and Labeo rohita) at a dose of about 15 mg/100 g body weight of the recipient. The spawning activity started about 6 to 10 hr after the administration of p...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(77)90158-5
更新日期：1977-07-01 00:00:00
abstract：:Cardiovascular disease is the leading cause of death worldwide and hypertension is the most common risk factor for death. Although many anti-hypertensive pharmacotherapies are approved for use in the United States, rates of hypertension have increased over the past decade. This review article summarizes a presentation...
journal_title：Physiology & behavior
pub_type： 杂志文章,评审
doi：10.1016/j.physbeh.2016.01.020
更新日期：2016-08-01 00:00:00
abstract：:There is considerable evidence suggesting that endogenous opioid peptides (EOP) might play a role in the defensive response to stressful stimuli. The stress associated with receipt of aggression from a female conspecific and physical restraint for collection of serial blood samples (at 10-min intervals) resulted in a ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(89)90241-2
更新日期：1989-05-01 00:00:00
abstract：:Twenty-four-hour recordings of electrophysiological correlates of the sleep-waking cycle in the rat were performed during different stages of cuff pedestal treatment. It was found that rats adapted to live on pedestals with the cuff raised displayed undisturbed patterns of sleep and wakefulness. Lowering the cuff for ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(84)90283-x
更新日期：1984-06-01 00:00:00
abstract：:Suppression of sham feeding by exogenous CCK-8 or intraintestinal oleate infusion is attenuated by peripheral administration of the CCK-A receptor antagonist, devazepide, but not by the CCK-B antagonist, L365260. Likewise, systemically administered devazepide increases food intake by real feeding rats. These results s...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(97)00519-2
更新日期：1998-02-15 00:00:00
abstract：:Jejunoileal bypass (JIB) surgery reduces food intake and body weight in obese humans and rats. Human bypass patients report visceral discomfort following surgery, and the present study assessed the aversive consequences of JIB in rats using a conditioned taste aversion paradigm. In Experiment 1 rats given a cherry-fla...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(85)90369-5
更新日期：1985-05-01 00:00:00
abstract：:The effects of FLA 336 on the attack by resident groups of female mice on strange female intruders were assessed. This MAO-type A inhibitor clearly suppressed attack in treated subjects without producing major alterations in other activities but there was no clear dose-response relationship. The substance also increas...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(93)90132-y
更新日期：1993-08-01 00:00:00
abstract：:Although cooperation represents a long-standing evolutionary puzzle, field studies on social carnivores have contributed greatly to our understanding of the selective forces favoring cooperative breeding. Despite these insights, our grasp of the proximate mechanisms facilitating cooperation in carnivores remains surpr...
journal_title：Physiology & behavior
pub_type： 杂志文章,评审
doi：10.1016/j.physbeh.2017.11.006
更新日期：2018-09-01 00:00:00
abstract：:Rats selectively display conditioned gaping reactions when re-exposed to flavours previously paired with nausea-inducing treatments and drugs that reduce nausea also reduce these reactions, suggesting that they represent a model of nausea-induced behavior in rats. However, these reactions rely upon learning, they are ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2011.10.017
更新日期：2012-02-01 00:00:00
abstract：:Schedule-induced polydipsia was studied in rats on a variable second-order schedule in Experiments 1 and 2. Drinking occurred only following presentations of the pellet reinforcer and was not induced by a stimulus that was associated with pellet delivery. Moreover, it was shown that lever pressing for food was not com...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(75)90158-4
更新日期：1975-02-01 00:00:00
abstract：:The aim of this study was to evaluate the effects of intraspecific social exposure (socialization vs rest) and habituation factors on the levels of urinary serotonin and cortisol [corrected respectively for creatinine to give the serotonin-creatinine ratio (5-HT/Cr) and cortisol-creatinine ratio (C/Cr)] and how they f...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2019.03.016
更新日期：2019-07-01 00:00:00
abstract：:Television viewing (TVV) has been linked with obesity, possibly through increased sedentary behavior and/or through increased ingestion during TVV. The proposition that TVV causes increased feeding, however, has not been subjected to experimental verification until recently. Our objective was to determine if the amoun...
journal_title：Physiology & behavior
pub_type： 临床试验,杂志文章
doi：10.1016/j.physbeh.2006.05.035
更新日期：2006-07-30 00:00:00
abstract：:Sea bass, a fish species characterized by its dualistic feeding pattern, was investigated to study the synchronizing effect of light and food on the demand-feeding rhythm. Nocturnal and diurnal sea bass, both in groups and individually, were exposed to restricted-feeding (RF) and light-dark (LD) cycles of different pe...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(95)00116-z
更新日期：1995-10-01 00:00:00
abstract：:In this article, we report findings from behavioral and neuroendocrine experiments in rats under pharmacologically induced antipyretic conditions. Endpoints included emotional fever, body weight setpoint, and in situ corticotropin-releasing hormone mRNA (CRHmRNA) expression. Nine male Wistar rats were treated with ace...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(02)01002-8
更新日期：2003-03-01 00:00:00
abstract：:This study analyzed in Balb/C mice the effects of individual housing on behavior, serum corticosterone and resistance to Ehrlich tumor growth. Mice (60 days old) were individually (IH) or grouped housed (G) (10-12 animals/cage) for 14-21 days. The 1st day of the housing condition was considered experimental day 1 (ED1...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2008.07.006
更新日期：2008-10-20 00:00:00
abstract：:Rats' voluntary ethanol intake varies with dispositional factors and energy status. The joint influences of these were of interest here. We previously reported that rats selectively bred for high voluntary saccharin intake (HiS) consume more ethanol and express more robust conditioning of preference for flavors paired...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2012.12.001
更新日期：2013-01-17 00:00:00
abstract：:A model of alcoholism should demonstrate self-administration of alcohol by the animal and a withdrawal syndrome when the animal no longer has access to the drug. A mouse model is described that meets these criteria and enables the induction of "alcoholism" in a large number of animals within a short period of time. Mi...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(82)90333-x
更新日期：1982-11-01 00:00:00
abstract：:Brief ether exposure induced high quality sexual receptivity in ovariectomized, estrogen-treated rats, presumably by increasing the secretion of adrenal progestins. Adrenalectomy completely blocked the effects of ether on this behavior. The onset of receptivity occurred 30--60 min following ether exposure; latencies m...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(77)90333-x
更新日期：1977-08-01 00:00:00
abstract：:Compared were the light-dark pattern of absolute energy intake and macronutrient selection of male Wistar rats intracerebroventricularly infused with glucagon (5 ng/h) or saline for 7 days in a three-way selection of macronutrients. Glucagon infusion induced a decrease in 24 h and nocturnal energy intake, whereas no s...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(95)02108-6
更新日期：1996-02-01 00:00:00
