High-resolution in vivo diffusion tensor imaging of the injured cat spinal cord using self-navigated, interleaved, variable-density spiral acquisition (SNAILS-DTI).

Abstract:

:Diffusion tensor magnetic resonance imaging (DTI) is useful for studying the microstructural changes in the spinal cord following traumatic injury; however, image quality is generally poor due to the small size of the spinal cord, physiological motion and susceptibility artifacts. Self-navigated, interleaved, variable-density spiral diffusion tensor imaging (SNAILS-DTI) is a distinctive pulse sequence that bypasses many of the challenges associated with DTI of the spinal cord, particularly if imaging gradient hardware is of conventional quality. In the current study, we have demonstrated the feasibility of implementing SNAILS-DTI on a clinical 3.0-T MR scanner and examined the effect of navigator filter parameters on image quality and reconstruction time. Results demonstrate high-quality, high-resolution (546 μm×546 μm) in vivo DTI images of the cat spinal cord after traumatic spinal cord injury.

journal_name

Magn Reson Imaging

authors

Ellingson BM,Sulaiman O,Kurpad SN

doi

10.1016/j.mri.2010.06.006

subject

Has Abstract

pub_date

2010-11-01 00:00:00

pages

1353-60

issue

9

eissn

0730-725X

issn

1873-5894

pii

S0730-725X(10)00163-3

journal_volume

28

pub_type

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