A lipase inhibitor monoterpene and monoterpene glycosides from Monarda punctata.

Abstract:

:An 80% acetone extract of Monarda punctata showed an inhibitory effect on lipase activity in isolated mouse plasma in vitro and carvacrol was obtained as the active constituent. It had an IC₅₀ value of 4.07 mM invitro and suppressed elevations in blood triacylglycerol levels in olive oil-loaded mice. Furthermore, from the whole plant, 22 compounds were isolated. Six monoterpene glycosides, a flavone glucuronide, and other known compounds were identified based on the results of spectroscopic analyses.

journal_name

Phytochemistry

journal_title

Phytochemistry

authors

Yamada K,Murata T,Kobayashi K,Miyase T,Yoshizaki F

doi

10.1016/j.phytochem.2010.08.009

subject

Has Abstract

pub_date

2010-11-01 00:00:00

pages

1884-91

issue

16

eissn

0031-9422

issn

1873-3700

pii

S0031-9422(10)00309-2

journal_volume

71

pub_type

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