Clinical impact of endoscopic papillectomy for benign-malignant borderline lesions of the major duodenal papilla.

abstract：:Revealing the mechanism of adult organ maintenance and regeneration after injury is fundamental to our understanding of the pathogenesis of diseases. Considering the results of pulse and chase experiments using inducible insulin-Cre or Elastase-Cre, and more recently HNF1b-Cre, adult pancreatic cells (beta, acinar, an...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Kawaguchi Y,Takaori K,Uemoto S

更新日期：2011-01-01 00:00:00

abstract：:Borderline resectable (BR) pancreatic cancer involves the portal vein and/or superior mesenteric vein (PV/SMV), major arteries including the superior mesenteric artery (SMA) or common hepatic artery (CHA), and sometimes includes the involvement of the celiac axis. We herein describe tips and tricks for a surgical tech...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Hirono S,Yamaue H

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Peroral pancreatoscopy (POPS) using a mother-baby endoscope system is often useful for assessment of intraductal papillary mucinous neoplasm (IPMN) of the pancreas with main pancreatic duct (MPD) involvement, but is not widely used for several reasons. The aim of this study was to evaluate the usefulness of ...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Nagayoshi Y,Aso T,Ohtsuka T,Kono H,Ideno N,Igarashi H,Takahata S,Oda Y,Ito T,Tanaka M

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:We investigated the aberrant expression of the STAT family in humans and liver fluke (Opisthorchis viverrini, Ov)-induced hamster cholangiocarcinoma (CCA) tissues. METHODS:The expression and phosphorylation of STAT1, STAT2, STAT3, STAT4, STAT5a, STAT5b and STAT6 in human hamster CCA tissues were immunohisto...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Dokduang H,Techasen A,Namwat N,Khuntikeo N,Pairojkul C,Murakami Y,Loilome W,Yongvanit P

更新日期：2014-10-01 00:00:00

abstract：:Segmentectomy is anatomical resection of segments based on the classification of Couinaud. This procedure is performed mainly for hepatocellular carcinoma. Invasion of portal vein and intrahepatic metastases often occur with hepatocellular carcinoma. Thus, it is desirable to perform anatomical resection of the cancer-...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Yoshida H,Katayose Y,Rikiyama T,Motoi F,Onogawa T,Egawa S,Unno M

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND/PURPOSE:Ampulla of Vater (AoV) carcinoma is a rare tumor that accounts for approximately 0.2% of gastrointestinal malignancies. There are no clinical guidelines concerning the treatment of AoV carcinoma. This study aimed to investigate the effectiveness of adjuvant treatment in AoV carcinoma following curati...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Kim HS,Jang JY,Yoon YS,Park SJ,Kwon W,Kim SW,Han HS,Han SS,Park JS,Yoon DS

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Delayed gastric emptying (DGE), a common postoperative complication of pancreaticoduodenectomy, is not considered a life-threatening complication. In the present study, we analyzed the risk factors for DGE and its impact on long-term prognosis. METHODS:We analyzed 383 patients who underwent pancreaticoduode...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Futagawa Y,Kanehira M,Furukawa K,Kitamura H,Yoshida S,Usuba T,Misawa T,Okamoto T,Yanaga K

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:A total of 26 pancreas transplants from brain dead donors, including 21 simultaneous pancreas and kidney (SPK) transplantation procedures, have been performed at Fujita Health University Hospital since the new pancreas transplant program was initiated in August 2012. The objective of this study is to investi...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Ito T,Kenmochi T,Ono S,Oshima M,Aida N,Suzuki A,Hasegawa M,Kusaka M,Hoshinaga K

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND/PURPOSE:Laparoscopic cholecystectomy is difficult to perform in patients with a low-lying costal arch that entirely covers the liver. We conducted this study to clarify the factors related to a low-lying costal arch and establish countermeasures to circumvent this characteristic. METHODS:The study included ...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Tajima Y,Kuroki T,Kitasato A,Adachi T,Kosaka T,Okamoto T,Fujita F,Kanetaka K,Susumu S,Mochizuki S,Torashima Y,Kanematsu T

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Postoperative pancreatic fistula (PF) remains a major complication after pancreaticoduodenectomy (PD). We aimed to investigate the predictors of clinically relevant PF after PD. METHODS:We retrospectively analyzed the predictive factors of relevant grade B/C PF using logistic regression analysis of 100 cons...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Kosaka H,Kuroda N,Suzumura K,Asano Y,Okada T,Fujimoto J

更新日期：2014-02-01 00:00:00

abstract：:The Milan criteria (MC) have been widely accepted as an effective way of selecting patients with early-stage hepatocellular carcinoma (HCC) for curative liver transplantation (LT). However, since a substantial subset of HCC patients exists that is beyond the MC but with the potential for good outcomes after LT, severa...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Takada Y,Tohyama T,Watanabe J

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:For the establishment of personalized therapy, we investigated biomarkers that can contribute to the selection of adjuvant therapy for pancreatic ductal adenocarcinoma (PDAC). METHODS:Between 2005 and 2014, of 141 consecutive patients with PDAC who underwent R0 or R1 resection, 61 patients given gemcitabine...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Oba A,Ban D,Kirimura S,Akahoshi K,Mitsunori Y,Matsumura S,Ochiai T,Kudo A,Tanaka S,Minoru T

更新日期：2016-08-01 00:00:00

abstract：:In the EASL and AASLD guidelines, hepatic resection (HR) is considered the first option for patients in stage 0 (very early HCC). This statement was not based on randomized controlled trials (RCTs) versus other therapies, but on the oncological assumption that HR is the better procedure for obtaining complete tumor ab...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Livraghi T

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Intrahepatic cholangiocarcinoma (IHC) is a rare liver malignancy with a rising incidence worldwide. Since no standard treatment has been established so far, the aim of this study was to assess the safety and efficacy of repeated liver resection and/or radiofrequency ablation (RFA) in selected cases with recu...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Kamphues C,Seehofer D,Eisele RM,Denecke T,Pratschke J,Neumann UP,Neuhaus P

更新日期：2010-07-01 00:00:00

abstract：:Considering that the Japanese (JPN) guidelines for the management of acute pancreatitis were published in Takada et al. (J HepatoBiliary Pancreat Surg 13:2-6, 2006), doubts will be cast as to the reason for publishing a revised edition of the Guidelines for the management of acute pancreatitis: the JPN guidelines 2010...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Takada T,Hirata K,Mayumi T,Yoshida M,Sekimoto M,Hirota M,Kimura Y,Takeda K,Isaji S,Wada K,Amano H,Gabata T,Arata S,Hirota M,Yokoe M,Kiriyama S,Nakayama T,Otomo K,Tanaka M,Shimosegawa T

更新日期：2010-01-01 00:00:00

abstract：:Heterogeneity is one of the essential hallmarks of malignancies. Within bulk cancer cells, a striking variability differs in biological characteristics including the proliferation rate, cell-cell interaction, metastatic tendency and even sensitivity to anticancer therapies. Such diversity makes the investigation and t...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Tanaka S

更新日期：2015-07-01 00:00:00

abstract：:Since the publication of the Tokyo Guidelines in 2007 and their revision in 2013, appropriate management for acute cholecystitis has been more clearly established. Since the last revision, several manuscripts, especially for alternative endoscopic techniques, have been reported; therefore, additional evaluation and re...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Mori Y,Itoi T,Baron TH,Takada T,Strasberg SM,Pitt HA,Ukai T,Shikata S,Noguchi Y,Teoh AYB,Kim MH,Asbun HJ,Endo I,Yokoe M,Miura F,Okamoto K,Suzuki K,Umezawa A,Iwashita Y,Hibi T,Wakabayashi G,Han HS,Yoon YS,Cho

更新日期：2018-01-01 00:00:00

abstract：:Highlight Takenaka and colleagues report on a novel bare uncovered self-expandable metal stent developed to be compatible with only 0.025-inch guide wires. This unprecedented feature makes the delivery tip thinner and more flexible than the conventional type and useful for endoscopic bilateral stent-in-stent placement...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Takenaka M,Nakai A,Kudo M

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND/PURPOSE:Pylorus-preserving pancreaticoduodenectomy (PPPD) is the treatment of choice for benign or premalignant pancreatic head lesions. Duodenum-preserving pancreatic head resection (DPPHR) has been reported in only 132 patients. This study aimed to compare the long-term results of DPPHR and PPPD. METHODS:...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Pedrazzoli S,Canton SA,Sperti C

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Latent pancreatic fistula (LPF) is difficult to diagnose during the early postoperative phase because of initially normal drain fluid amylase (DFA) levels. The present study investigated the clinical significance and risk factors of LPF after pancreatoduodenectomy. METHODS:A total of 662 patients who underw...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Ohgi K,Yamamoto Y,Sugiura T,Okamura Y,Ito T,Ashida R,Uesaka K

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:The effects of ablation with various settings of powers and times using a newly developed radiofrequency (RF) ablation device, the Habib™ EndoHPB catheter, are not well known. In the present study, we examined the effects of a novel RF ablation catheter using resected fresh pig livers and evaluated the macro...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Itoi T,Isayama H,Sofuni A,Itokawa F,Tamura M,Watanabe Y,Moriyasu F,Kahaleh M,Habib N,Nagao T,Yokoyama T,Kasuya K,Kawakami H

更新日期：2012-09-01 00:00:00

abstract：:Enormous efforts have been made to establish pancreatic stem/progenitor cells as a source for regenerative medicine for the treatment of diabetes mellitus. In recent years, it has been recognized that the self-renewal of beta cells is the dominant process involved in postnatal beta-cell regeneration and expansion. Nev...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Sekine K,Taniguchi H

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Acute portal pressure rise is occasionally observed during intraportal islet infusion, especially in islet autotransplantation (IAT) where tissue purification is rarely applied. In this paper we investigate factors associated with acute portal pressure rise, a known risk factor for portal vein thrombosis. M...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Kawahara T,Kin T,Shapiro AM

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND/PURPOSE:To describe surgical techniques and results of right hepatic lobectomy (RHL) with thoracotomy. METHODS:This procedure consists of laparotomy and thoracotomy, cholecystectomy, division of the right hepatic artery and right portal vein, mobilization of the liver, division of the right hepatic vein, tr...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Kubota K

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND/PURPOSE:In spite of the great risk involved, the donor bile duct division procedure has not been thoroughly addressed in the literature. The purpose of this study is to show the appropriate approach to bile duct division in living donor hepatectomy. METHODS:Of 87 living donor liver surgeries, we performed b...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Takatsuki M,Eguchi S,Yamanouchi K,Hidaka M,Soyama A,Kanematsu T

更新日期：2011-03-01 00:00:00

abstract：PURPOSE:This study aimed to elucidate the characteristics of biliary tract carcinoma (BTC) in young patients. METHODS:This is a nationwide multicenter, retrospective cohort study supervised by the Japanese Society of Hepato-Biliary-Pancreatic Surgery (JSHBPS). Clinicopathological data of patients aged <50 years diagno...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Ariake K,Unno M,Yoshida H,Kubo S,Horiguchi A,Yamaue H,Yamamoto M

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:The aim of the present study was to analyze the outcome of laparoscopic approach specifically in patients with Intermediate-stage disease and to define the differential benefit with Early-stage patients. METHODS:Six hundred twenty-two resections for HCC were dichotomized according to staging (Early and Inter...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Ratti F,Cipriani F,Fiorentini G,Catena M,Paganelli M,Aldrighetti L

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:IgG4-sclerosing cholangitis (IgG4-SC) patients have an increased level of serum IgG4, dense infiltration of IgG4-positive plasma cells with extensive fibrosis in the bile duct wall, and a good response to steroid therapy. However, it is not easy to distinguish IgG4-SC from primary sclerosing cholangitis, pan...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Ohara H,Okazaki K,Tsubouchi H,Inui K,Kawa S,Kamisawa T,Tazuma S,Uchida K,Hirano K,Yoshida H,Nishino T,Ko SB,Mizuno N,Hamano H,Kanno A,Notohara K,Hasebe O,Nakazawa T,Nakanuma Y,Takikawa H,Research Committee of IgG4

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:To investigate the potential anti-tumoral properties of propofol in pancreatic cancer and elucidate the underlying mechanisms. METHODS:The relative expression of ADAM metallopeptidase domain 8 (ADAM8) in response to hypoxia in Panc1 cells was analyzed by western blotting. The enzymatic activity was determin...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Gao Y,Yu X,Zhang F,Dai J

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:We aimed to clarify the clinical usefulness of one-step self-expandable metal stent (SEMS) placement for distal malignant biliary obstruction by comparing with two-step SEMS placement. METHODS:We retrospectively compared early complications, bilirubin level decreasing rate, and period of hospitalization bet...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Shimizu S,Naitoh I,Nakazawa T,Hayashi K,Miyabe K,Kondo H,Yoshida M,Yamashita H,Ohara H,Joh T

更新日期：2014-03-01 00:00:00