Propofol inhibits pancreatic cancer progress under hypoxia via ADAM8.

abstract：BACKGROUND:Delayed gastric emptying (DGE), a common postoperative complication of pancreaticoduodenectomy, is not considered a life-threatening complication. In the present study, we analyzed the risk factors for DGE and its impact on long-term prognosis. METHODS:We analyzed 383 patients who underwent pancreaticoduode...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Futagawa Y,Kanehira M,Furukawa K,Kitamura H,Yoshida S,Usuba T,Misawa T,Okamoto T,Yanaga K

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND/PURPOSE:In spite of the great risk involved, the donor bile duct division procedure has not been thoroughly addressed in the literature. The purpose of this study is to show the appropriate approach to bile duct division in living donor hepatectomy. METHODS:Of 87 living donor liver surgeries, we performed b...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Takatsuki M,Eguchi S,Yamanouchi K,Hidaka M,Soyama A,Kanematsu T

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND/PURPOSE:Hilar cholangiocarcinoma and intrahepatic cholangiocarcinoma involving the hepatic hilus are defined as "perihilar cholangiocarcinoma". The principle of surgical treatment is hemi-hepatectomy or trisectionectomy of the liver, caudate lobectomy, and resection of the extrahepatic bile duct for complete...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Unno M,Katayose Y,Rikiyama T,Yoshida H,Yamamoto K,Morikawa T,Hayashi H,Motoi F,Egawa S

更新日期：2010-07-01 00:00:00

abstract：:Advances in the field of minimally invasive surgery have grown since the original advent of conventional multiport laparoscopic surgery. The recent development of single incision laparoscopic surgery remains a relatively novel technique, and has had mixed reviews as to whether it has been associated with lower pain sc...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Qadan M,Curet MJ,Wren SM

更新日期：2014-01-01 00:00:00

abstract：:Liver function reserve estimation is important for selecting the appropriate patients for hepatectomy or ablation of tumors. Many liver function tests have been devised, but the indocyanine green (ICG) clearance test remains the most popular for its simplicity and perhaps accuracy. Compared with the Child-Pugh classif...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Fan ST

更新日期：2010-07-01 00:00:00

abstract：:Since the publication of the Tokyo Guidelines in 2007 and their revision in 2013, appropriate management for acute cholecystitis has been more clearly established. Since the last revision, several manuscripts, especially for alternative endoscopic techniques, have been reported; therefore, additional evaluation and re...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Mori Y,Itoi T,Baron TH,Takada T,Strasberg SM,Pitt HA,Ukai T,Shikata S,Noguchi Y,Teoh AYB,Kim MH,Asbun HJ,Endo I,Yokoe M,Miura F,Okamoto K,Suzuki K,Umezawa A,Iwashita Y,Hibi T,Wakabayashi G,Han HS,Yoon YS,Cho

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Drip infusion cholangiography with computed tomography (DIC-CT) is a major preoperative modality used for patients undergoing laparoscopic cholecystectomy (LC). METHODS:This study included 218 patients for whom preoperative DIC-CT images were obtained prior to undergoing LC. The association between gallblad...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Nakazawa A,Akamatsu N,Miyata Y,Komagome M,Maki A,Arita J,Ishizawa T,Kaneko J,Beck Y,Hasegawa K

更新日期：2020-06-01 00:00:00

abstract：:Although the diagnostic and severity grading criteria on the 2013 Tokyo Guidelines (TG13) are used worldwide as the primary standard for management of acute cholangitis (AC), they need to be validated through implementation and assessment in actual clinical practice. Here, we conduct a systematic review of the literat...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Kiriyama S,Kozaka K,Takada T,Strasberg SM,Pitt HA,Gabata T,Hata J,Liau KH,Miura F,Horiguchi A,Liu KH,Su CH,Wada K,Jagannath P,Itoi T,Gouma DJ,Mori Y,Mukai S,Giménez ME,Huang WS,Kim MH,Okamoto K,Belli G,Derve

更新日期：2018-01-01 00:00:00

abstract：:Surgical resection is the only hope for cure in patients with pancreatic cancer. To improve the resectability and achieve better prognosis of this lethal disease, extended resection for pancreatic cancer has been applied. We have performed portal vein resection aggressively for pancreatic cancer with portal vein invas...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Yoshitomi H,Kato A,Shimizu H,Ohtsuka M,Furukawa K,Takayashiki T,Kuboki S,Takano S,Okamura D,Suzuki D,Sakai N,Kagawa S,Miyazaki M

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Postoperative pancreatic fistula (POPF) after distal pancreatectomy (DP) remains the most common surgical complication. We have developed a novel stump closure technique after DP using transpancreatic mattress suture with Vicryl mesh (TMV) and reported our initial findings. The purpose of this study is to ev...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Yoshida Y,Matsumoto I,Matsumoto M,Kawaguchi K,Murase T,Kamei K,Satoi S,Takebe A,Nakai T,Takeyama Y

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Pancreaticobiliary malignant diseases are primarily treated by surgical resection. However, the surgical indications for elderly patients, especially for pancreaticoduodenectomy (PD), must be carefully considered due to patient compliance. Whether PD can contribute to better prognoses in elderly patients rem...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Yamashita M,Adachi T,Ono S,Matsumura N,Adachi T,Natsuda K,Hidaka M,Eguchi S

更新日期：2020-10-15 00:00:00

abstract：BACKGROUND:Imaging study cannot identify patients with potential low-risk for lymph node (LN) metastasis in intrahepatic cholangiocarcinoma (ICC). The purpose of this study was to identify a low-risk group for LN metastasis in ICC using preoperatively available factors. METHODS:Data from 127 consecutive patients, who ...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Yoh T,Hatano E,Seo S,Terajima H,Uchida Y,Taura K,Yasuchika K,Uemoto S

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND/PURPOSE:To describe surgical techniques and results of right hepatic lobectomy (RHL) with thoracotomy. METHODS:This procedure consists of laparotomy and thoracotomy, cholecystectomy, division of the right hepatic artery and right portal vein, mobilization of the liver, division of the right hepatic vein, tr...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Kubota K

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:We aimed to clarify the appropriate timing for performing percutaneous transhepatic gallbladder drainage (PTGBD) and cholecystectomy, and the effect of PTGBD on surgical difficulty in acute cholecystitis patients. METHODS:We retrospectively examined 46 patients who underwent laparoscopic cholecystectomy (LC...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Yamada K,Yamashita Y,Yamada T,Takeno S,Noritomi T

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND/PURPOSE:S-1 is a new oral fluoropyrimidine anticancer agent shown to be effective for pancreatic cancer. In a previous phase I trial, we evaluated the safety of S-1 combined with radiotherapy to determine the maximum tolerated dose and dose-limiting toxicity in patients with unresectable pancreatic cancer. T...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Shinchi H,Maemura K,Mataki Y,Kurahara H,Sakoda M,Ueno S,Hiraki Y,Nakajo M,Natsugoe S,Takao S

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Thrombospondin-1 (THBS-1), a glycoprotein, is an endogenous inhibitor of angiogenesis and tumor growth. In this study, we investigated the clinical role and mechanism of THBS-1 expression in colorectal liver metastases, focusing on the relationships between its expression and tumor growth, epithelial-mesench...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Teraoku H,Morine Y,Ikemoto T,Saito Y,Yamada S,Yoshikawa M,Takasu C,Higashijima J,Imura S,Shimada M

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Tokyo Guideline 2013 (TG13) proposed three drainage techniques for the treatment of acute cholecystitis. We evaluated the clinical efficacy and adverse events between percutaneous transhepatic intervention (PTGBI) including percutaneous transhepatic gallbladder drainage (PTGBD) and percutaneous transhepatic ...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Itoi T,Takada T,Hwang TL,Endo I,Akazawa K,Miura F,Chen MF,Jan YY,Ker CG,Wang HP,Gomi H,Yokoe M,Kiriyama S,Wada K,Yamaue H,Miyazaki M,Yamamoto M

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Our previous randomized controlled trial revealed no difference in 2-year overall survival (OS) between extended and standard resection for pancreatic adenocarcinoma. The present study evaluated the 5-year OS and recurrence patterns according to the extent of pancreatectomy. METHODS:Between 2006 and 2009, 1...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Jang JY,Kang JS,Han Y,Heo JS,Choi SH,Choi DW,Park SJ,Han SS,Yoon DS,Park JS,Yu HC,Kang KJ,Kim SG,Lee H,Kwon W,Yoon YS,Han HS,Kim SW

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:The effects of ablation with various settings of powers and times using a newly developed radiofrequency (RF) ablation device, the Habib™ EndoHPB catheter, are not well known. In the present study, we examined the effects of a novel RF ablation catheter using resected fresh pig livers and evaluated the macro...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Itoi T,Isayama H,Sofuni A,Itokawa F,Tamura M,Watanabe Y,Moriyasu F,Kahaleh M,Habib N,Nagao T,Yokoyama T,Kasuya K,Kawakami H

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:There have been no reports showing the incidence of anastomotic stenosis of continuous hepaticojejunostomy (HJ) and identifying its risk factors for patients who underwent pancreaticoduodenectomy (PD). METHOD:We retrospectively investigated 200 patients whose HJ was established by unified method, single lay...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Asano T,Natsume S,Senda Y,Sano T,Matsuo K,Kodera Y,Hara K,Ito S,Yamao K,Shimizu Y

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Whether systemically transplanted human adipose-derived stem cells (ADSCs) homed to the injured liver in nude mice under stress with subsequent hepatectomy (Hx) and ischemia-reperfusion (I/R) was investigated in the present study. The types of cells in the liver that were involved in the homing of ADSCs were...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Saito Y,Shimada M,Utsunomiya T,Ikemoto T,Yamada S,Morine Y,Imura S,Mori H,Arakawa Y,Kanamoto M,Iwahashi S,Takasu C

更新日期：2014-12-01 00:00:00

abstract：:Until now, there have been no practical clinical guidelines for congenital biliary dilatation (CBD). In this review article, the Japanese Study Group on Congenital Biliary Dilatation (JSCBD) propose to establish clinical practice guidelines for CBD. Because the evidence-based literature is relatively small, we decided...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Ishibashi H,Shimada M,Kamisawa T,Fujii H,Hamada Y,Kubota M,Urushihara N,Endo I,Nio M,Taguchi T,Ando H,Japanese Study Group on Congenital Biliary Dilatation (JSCBD).

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:The use of cadaveric vein allografts was first described by our group as a feasible option for venous reconstruction. The aim of this study was to report long-term results of this innovative technique. METHODS:Cold-stored veins harvested from donor cadavers were used as homologous grafts for venous reconstr...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Meniconi RL,Santoro R,Guglielmo N,Vennarecci G,Lepiane P,Colasanti M,Ettorre GM

更新日期：2016-01-01 00:00:00

abstract：:Mucobilia is a rare pathologic condition characterized by the abnormal secretion and accumulation of abundant mucus within the biliary tree. It is usually seen in association with mucin-producing hepatobiliary and pancreatic tumors. Neoplastic transformation of these tumors can range from low-grade dysplasia to invasi...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Brown MA,Sakpal SV,Chamberlain RS

更新日期：2010-05-01 00:00:00

abstract：:Surgical intervention and, more recently, endoscopic intervention have been performed for the treatment of malignant gastric outlet obstruction. Recently, endoscopic ultrasonography (EUS)-guided gastrojejunostomy using special devices has been established. In line with this, we have developed a novel EUS-guided double...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Itoi T,Ishii K,Tanaka R,Umeda J,Tonozuka R

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Peroral pancreatoscopy (POPS) using a mother-baby endoscope system is often useful for assessment of intraductal papillary mucinous neoplasm (IPMN) of the pancreas with main pancreatic duct (MPD) involvement, but is not widely used for several reasons. The aim of this study was to evaluate the usefulness of ...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Nagayoshi Y,Aso T,Ohtsuka T,Kono H,Ideno N,Igarashi H,Takahata S,Oda Y,Ito T,Tanaka M

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND/PURPOSE:Sinisan, a traditional Chinese medicine, is effective for the treatment of gastrointestinal disorders. In this study, we investigated the potential protective role of Sinisan against chronic pancreatitis (CP) in rats. METHODS:CP was induced in rats by intrapancreatic injection of trinitrobenzene sul...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Tang Y,Liao Y,Kawaguchi-Sakita N,Raut V,Fakhrejahani E,Qian N,Toi M

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Since the publication of the Tokyo Guidelines (TG13) for the management of acute cholecystitis (AC), multidirectional studies have been published. However, epidemiological research about AC with big data was not projected. The aim of this study was to reveal the actual clinical conditions of AC. METHOD:The ...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Yokoe M,Takada T,Hwang TL,Endo I,Akazawa K,Miura F,Mayumi T,Mori R,Chen MF,Jan YY,Ker CG,Wang HP,Itoi T,Gomi H,Kiriyama S,Wada K,Yamaue H,Miyazaki M,Yamamoto M

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Latent pancreatic fistula (LPF) is difficult to diagnose during the early postoperative phase because of initially normal drain fluid amylase (DFA) levels. The present study investigated the clinical significance and risk factors of LPF after pancreatoduodenectomy. METHODS:A total of 662 patients who underw...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Ohgi K,Yamamoto Y,Sugiura T,Okamura Y,Ito T,Ashida R,Uesaka K

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:IgG4-sclerosing cholangitis (IgG4-SC) patients have an increased level of serum IgG4, dense infiltration of IgG4-positive plasma cells with extensive fibrosis in the bile duct wall, and a good response to steroid therapy. However, it is not easy to distinguish IgG4-SC from primary sclerosing cholangitis, pan...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Ohara H,Okazaki K,Tsubouchi H,Inui K,Kawa S,Kamisawa T,Tazuma S,Uchida K,Hirano K,Yoshida H,Nishino T,Ko SB,Mizuno N,Hamano H,Kanno A,Notohara K,Hasebe O,Nakazawa T,Nakanuma Y,Takikawa H,Research Committee of IgG4

更新日期：2012-09-01 00:00:00