STATs profiling reveals predominantly-activated STAT3 in cholangiocarcinoma genesis and progression.

abstract：BACKGROUND:Acute portal pressure rise is occasionally observed during intraportal islet infusion, especially in islet autotransplantation (IAT) where tissue purification is rarely applied. In this paper we investigate factors associated with acute portal pressure rise, a known risk factor for portal vein thrombosis. M...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Kawahara T,Kin T,Shapiro AM

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:The use of cadaveric vein allografts was first described by our group as a feasible option for venous reconstruction. The aim of this study was to report long-term results of this innovative technique. METHODS:Cold-stored veins harvested from donor cadavers were used as homologous grafts for venous reconstr...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Meniconi RL,Santoro R,Guglielmo N,Vennarecci G,Lepiane P,Colasanti M,Ettorre GM

更新日期：2016-01-01 00:00:00

abstract：:Lactate measurements have proven utility as a triage tool, therapeutic guide, and prognostic indicator, with broad use in Acute Care and transplantation. Its value in guiding therapy and predicting outcomes following liver resection is less well-defined. This systematic review in accordance with Preferred Reporting It...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Connolly C,Stättner S,Niederwieser T,Primavesi F

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Hypoxia is an important condition to promote angiogenesis that is essential to tumor progression, including pancreatic ductal adenocarcinoma (PDAC). We evaluated whether the immunohistochemistry for hypoxia inducible factor-1α (HIF-1α) was correlated with hepatic metastases in PDAC. METHODS:We examined the ...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Matsuo Y,Ding Q,Desaki R,Maemura K,Mataki Y,Shinchi H,Natsugoe S,Takao S

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:There are no multicenter studies on the influence of diabetes duration on pancreatic transplant outcomes. Our study aimed to determine how type 1 diabetes duration influenced survival of pancreatic grafts. METHODS:The data of 8,139 patients who received pancreas transplants during 2006-2015 were extracted f...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Zhou J,Dong Y,Mei S,Gu Y,Li Z,Xiang J,Zheng H,Chen Z,Huang Z,Hu Z

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND AND STUDY AIMS:Expression of the forkhead/winged helix family of transcription factor P3+ regulatory T cells (FOXP3(+) Treg), a master gene of regulatory T cells (Treg) is observed in patients with autoimmune pancreatitis (AIP). We investigated the usefulness of detection of FOXP3(+) Treg in the main duodena...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Kubota K,Kato S,Watanabe S,Fujita K,Yoneda M,Takahashi H,Inamori M,Shimamura T,Kirikoshi H,Kobayashi N,Saito S,Hisatomi K,Matsuhashi N,Nakajima A

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Sex is thought to play a significant role in predicting outcomes in numerous diseases. The role sex plays in acute pancreatitis (AP) remains limited. We sought to determine if sex is associated with hospitalization outcomes in this population, using a large national database. METHODS:This was a retrospectiv...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Sharma S,Weissman S,Aburayyan K,Acharya A,Aziz M,Systrom HK,Lew D,Vohra I,Feuerstein JD,Pandol SJ

更新日期：2021-01-08 00:00:00

abstract：:Steady progress is being made in endoscopic biliary intervention, especially endoscopic ultrasonography (EUS)-guided procedures. The EUS-guided rendezvous technique (EUS-RV) is a salvage method for failed selective biliary cannulation. The overall success rate of EUS-RV in 247 cases from seven published articles was 7...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Isayama H,Nakai Y,Kawakubo K,Kawakami H,Itoi T,Yamamoto N,Kogure H,Koike K

更新日期：2013-04-01 00:00:00

abstract：PURPOSE:We report two cases in which portal blood flow via the peribiliary vascular plexus (PBP) was clearly demonstrated using contrast-enhanced intra-operative ultrasonography (CE-IOUS). METHODS:Two patients who underwent hemihepatectomies were investigated using CE-IOUS. Before injection of the contrast medium, bot...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Uchikawa Y,Kitamura H,Miyagawa S

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND/PURPOSE:It is generally thought that an internal short stent placed across the pancreaticojejunostomy (PJ) following pancreatoduodenectomy (PD) usually passes spontaneously through the rectum thereafter; however, we experienced some patients who presented with pancreatitis and cholangitis owing to delayed de...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Kadowaki S,Miura F,Amano H,Toyota N,Wada K,Shibuya M,Maeno S,Takada T,Sano K

更新日期：2012-09-01 00:00:00

abstract：PURPOSE:Although left-sided hepatectomy, such as a left hepatectomy or left trisectionectomy with resection of the caudate lobe and extrahepatic bile duct, is used to treat hilar cholangiocarcinoma predominantly involving the left side of the hepatic hilum, it is associated with several difficult technical points. The ...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Uesaka K

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:The influence of donor-recipient gender mismatch on outcomes after liver transplantation (LT) is controversial. The aim of this study was to evaluate the effect of donor and recipient gender discordance on graft survival. METHODS:All patients who underwent primary LT from 1994-2012 at a single-center were i...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Croome KP,Segal D,Hernandez-Alejandro R,Adams PC,Thomson A,Chandok N

更新日期：2014-04-01 00:00:00

abstract：:Revealing the mechanism of adult organ maintenance and regeneration after injury is fundamental to our understanding of the pathogenesis of diseases. Considering the results of pulse and chase experiments using inducible insulin-Cre or Elastase-Cre, and more recently HNF1b-Cre, adult pancreatic cells (beta, acinar, an...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Kawaguchi Y,Takaori K,Uemoto S

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Intraductal oncocytic papillary neoplasms (IOPN) are rare tumors of the pancreatic and biliary ductal system. It is not absolutely clear if the molecular and clinicopathologic characteristics of IOPN differ significantly from other related lesions, namely intraductal papillary mucinous neoplasms (IPMN). Ther...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Liszka L,Pajak J,Zielińska-Pajak E,Krzych L,Gołka D,Mrowiec S,Lampe P

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND/PURPOSE:Hilar cholangiocarcinoma and intrahepatic cholangiocarcinoma involving the hepatic hilus are defined as "perihilar cholangiocarcinoma". The principle of surgical treatment is hemi-hepatectomy or trisectionectomy of the liver, caudate lobectomy, and resection of the extrahepatic bile duct for complete...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Unno M,Katayose Y,Rikiyama T,Yoshida H,Yamamoto K,Morikawa T,Hayashi H,Motoi F,Egawa S

更新日期：2010-07-01 00:00:00

abstract：:Many authors at high-volume centers all over the world have reported improved outcomes of hilar cholangiocarcinoma by several aggressive surgical approaches such as extended hepatic resection, combined vascular resection, and hepatopancreaticoduodenectomy in recent years. There has been great progress in the surgical ...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Miyazaki M,Kimura F,Shimizu H,Yoshidome H,Otuka M,Kato A,Yoshitomi H,Furukawa K,Takeuchi D,Takayashiki T,Suda K,Takano S

更新日期：2010-07-01 00:00:00

abstract：OBJECTIVE:The aim of the present study was to analyze the outcome of laparoscopic approach specifically in patients with Intermediate-stage disease and to define the differential benefit with Early-stage patients. METHODS:Six hundred twenty-two resections for HCC were dichotomized according to staging (Early and Inter...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Ratti F,Cipriani F,Fiorentini G,Catena M,Paganelli M,Aldrighetti L

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Aspirin is widely used for the secondary prevention of ischemic stroke and cardiovascular disease. Perioperative aspirin may decrease thrombotic morbidity, but may also increase hemorrhagic morbidity. In particular, liver resection carries risks of bleeding, leading to higher risks of hemorrhagic morbidity. ...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Monden K,Sadamori H,Hioki M,Ohno S,Saneto H,Ueki T,Yabushita K,Ono K,Sakaguchi K,Takakura N

更新日期：2017-07-01 00:00:00

abstract：:Highlight Although recent advances in robotic surgery have enabled more precise movements of the needle driver, a sophisticated laparoscopic suturing technique is still desired. Honda and colleagues describe the basic knowledge of and a small but useful trick for atraumatic needle driving in laparoscopic suturing, bas...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Honda G,Ome Y,Yoshida N,Kawamoto Y

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND/PURPOSE:Laparoscopic cholecystectomy is difficult to perform in patients with a low-lying costal arch that entirely covers the liver. We conducted this study to clarify the factors related to a low-lying costal arch and establish countermeasures to circumvent this characteristic. METHODS:The study included ...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Tajima Y,Kuroki T,Kitasato A,Adachi T,Kosaka T,Okamoto T,Fujita F,Kanetaka K,Susumu S,Mochizuki S,Torashima Y,Kanematsu T

更新日期：2011-01-01 00:00:00

abstract：:Liver transplantation (LT) has been regarded as "potentially curative" in a cirrhotic patient with hepatocellular carcinoma (HCC) because it removes the cancer and eradicates the cirrhosis. In Taiwan, HCC ranks first among the leading causes of cancer mortality in males and 4th in females. The most common causes are c...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Chen CL,Concejero AM

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Thrombospondin-1 (THBS-1), a glycoprotein, is an endogenous inhibitor of angiogenesis and tumor growth. In this study, we investigated the clinical role and mechanism of THBS-1 expression in colorectal liver metastases, focusing on the relationships between its expression and tumor growth, epithelial-mesench...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Teraoku H,Morine Y,Ikemoto T,Saito Y,Yamada S,Yoshikawa M,Takasu C,Higashijima J,Imura S,Shimada M

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Whether systemically transplanted human adipose-derived stem cells (ADSCs) homed to the injured liver in nude mice under stress with subsequent hepatectomy (Hx) and ischemia-reperfusion (I/R) was investigated in the present study. The types of cells in the liver that were involved in the homing of ADSCs were...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Saito Y,Shimada M,Utsunomiya T,Ikemoto T,Yamada S,Morine Y,Imura S,Mori H,Arakawa Y,Kanamoto M,Iwahashi S,Takasu C

更新日期：2014-12-01 00:00:00

abstract：:Surgical intervention and, more recently, endoscopic intervention have been performed for the treatment of malignant gastric outlet obstruction. Recently, endoscopic ultrasonography (EUS)-guided gastrojejunostomy using special devices has been established. In line with this, we have developed a novel EUS-guided double...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Itoi T,Ishii K,Tanaka R,Umeda J,Tonozuka R

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Resection using a stapler is a popular approach to distal pancreatectomy. However, the resulting leakage of pancreatic juice represents a serious problem. We have developed a force-fluorescence measurement as a first step towards the quantitative evaluation of pancreatic leakage due to tissue tearing under c...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Kobayashi E,Tsuchiya S,Akagi Y,Tomii N,Nakagawa K,Inai K,Muragaki Y,Asano T,Kim D

更新日期：2020-11-01 00:00:00

abstract：:Considering that the Japanese (JPN) guidelines for the management of acute pancreatitis were published in Takada et al. (J HepatoBiliary Pancreat Surg 13:2-6, 2006), doubts will be cast as to the reason for publishing a revised edition of the Guidelines for the management of acute pancreatitis: the JPN guidelines 2010...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Takada T,Hirata K,Mayumi T,Yoshida M,Sekimoto M,Hirota M,Kimura Y,Takeda K,Isaji S,Wada K,Amano H,Gabata T,Arata S,Hirota M,Yokoe M,Kiriyama S,Nakayama T,Otomo K,Tanaka M,Shimosegawa T

更新日期：2010-01-01 00:00:00

abstract：:Although the diagnostic and severity grading criteria on the 2013 Tokyo Guidelines (TG13) are used worldwide as the primary standard for management of acute cholangitis (AC), they need to be validated through implementation and assessment in actual clinical practice. Here, we conduct a systematic review of the literat...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Kiriyama S,Kozaka K,Takada T,Strasberg SM,Pitt HA,Gabata T,Hata J,Liau KH,Miura F,Horiguchi A,Liu KH,Su CH,Wada K,Jagannath P,Itoi T,Gouma DJ,Mori Y,Mukai S,Giménez ME,Huang WS,Kim MH,Okamoto K,Belli G,Derve

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:To investigate the potential anti-tumoral properties of propofol in pancreatic cancer and elucidate the underlying mechanisms. METHODS:The relative expression of ADAM metallopeptidase domain 8 (ADAM8) in response to hypoxia in Panc1 cells was analyzed by western blotting. The enzymatic activity was determin...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Gao Y,Yu X,Zhang F,Dai J

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Pancreatoduodenectomy (PD) carries a high morbidity. Over time, pancreatic surgeons have altered their perioperative management in efforts to reduce morbidity rates, thereby creating major technical and management variations. We aim to evaluate the practice patterns of hepato-pancreato-biliary (HPB) surgeons...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Macedo FIB,Mowzoon M,Parikh J,Sathyanarayana SA,Jacobs MJ

更新日期：2017-05-01 00:00:00

abstract：INTRODUCTION:Laparoscopic cholecystectomy (LC) is considered difficult in patients with an impacted gallstone (IG). We examined the efficacy of releasing an IG after percutaneous transhepatic gallbladder drainage (PTGBD) for acute cholecystitis (AC) and the usefulness of the Difficulty Score (DS) proposed in the Tokyo ...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Fujinaga A,Iwashita Y,Tada K,Watanabe K,Kawasaki T,Masuda T,Hirashita T,Endo Y,Ohta M,Inomata M

更新日期：2020-10-31 00:00:00