Abstract:
BACKGROUND:There are no multicenter studies on the influence of diabetes duration on pancreatic transplant outcomes. Our study aimed to determine how type 1 diabetes duration influenced survival of pancreatic grafts. METHODS:The data of 8,139 patients who received pancreas transplants during 2006-2015 were extracted from the Scientific Registry of Transplant Recipients database. Patients were separated into two groups according to duration of diabetes: S group (diabetes ≤20 years) and L group (>20 years). RESULTS:Compared to S group, L group were older and prone to be male, to have higher body mass index, to receive pancreas after kidney transplantation (PAK), and to be White. Patient survival was not significantly different between the two groups, but pancreatic survival was better in the L group (hazard ratio 0.88; P = 0.012). Pancreatic survival of L group was better than S group in pancreas transplant alone and simultaneous pancreas-kidney transplantation (SPK). Graft survival was not significant different between the two groups in PAK. Diabetes duration was an independent predictor of graft survival in SPK patients (hazard ratio 0.86; P = 0.012). CONCLUSIONS:Diabetes duration has no influence on patient survival. However, long duration of type 1 diabetes mellitus appears to be protective against pancreatic graft loss.
journal_name
J Hepatobiliary Pancreat Scijournal_title
Journal of hepato-biliary-pancreatic sciencesauthors
Zhou J,Dong Y,Mei S,Gu Y,Li Z,Xiang J,Zheng H,Chen Z,Huang Z,Hu Zdoi
10.1002/jhbp.677subject
Has Abstractpub_date
2019-12-01 00:00:00pages
583-592issue
12eissn
1868-6974issn
1868-6982journal_volume
26pub_type
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journal_title:Journal of hepato-biliary-pancreatic sciences
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journal_title:Journal of hepato-biliary-pancreatic sciences
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journal_title:Journal of hepato-biliary-pancreatic sciences
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更新日期:2018-06-01 00:00:00
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更新日期:2017-05-01 00:00:00
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journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章
doi:10.1007/s00534-009-0207-2
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pub_type: 杂志文章,多中心研究
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更新日期:2010-11-01 00:00:00
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pub_type: 评论,杂志文章
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更新日期:2011-03-01 00:00:00
abstract:BACKGROUND:Drip infusion cholangiography with computed tomography (DIC-CT) is a major preoperative modality used for patients undergoing laparoscopic cholecystectomy (LC). METHODS:This study included 218 patients for whom preoperative DIC-CT images were obtained prior to undergoing LC. The association between gallblad...
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pub_type: 杂志文章
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