Reappraisal of the advantages of laparoscopic liver resection for intermediate hepatocellular carcinoma within a stage migration perspective: Propensity score analysis of the differential benefit.

abstract：BACKGROUND/PURPOSE:In bile duct carcinoma (BDC) patients, bile aspiration cytology (BAC) is an established method for cytodiagnosis. However, almost all previous reports investigated the biliary strictures caused not only by BDC but also by gallbladder and pancreatic carcinomas. Therefore, BAC in BDC patients only has ...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Abdelghani YA,Arisaka Y,Masuda D,Takii M,Ashida R,Makhlouf MM,Fouad YM,Tsuji M,Kurisu Y,Higuchi K

更新日期：2012-07-01 00:00:00

abstract：:Revealing the mechanism of adult organ maintenance and regeneration after injury is fundamental to our understanding of the pathogenesis of diseases. Considering the results of pulse and chase experiments using inducible insulin-Cre or Elastase-Cre, and more recently HNF1b-Cre, adult pancreatic cells (beta, acinar, an...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Kawaguchi Y,Takaori K,Uemoto S

更新日期：2011-01-01 00:00:00

abstract：:Borderline resectable (BR) pancreatic cancer involves the portal vein and/or superior mesenteric vein (PV/SMV), major arteries including the superior mesenteric artery (SMA) or common hepatic artery (CHA), and sometimes includes the involvement of the celiac axis. We herein describe tips and tricks for a surgical tech...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Hirono S,Yamaue H

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Indocyanine green (ICG) is a synthetic dye that is widely used to evaluate liver function in critically ill patients, before liver resection or after liver transplantation. Controversy still exists about the impact exerted on the ICG ratio after 15 min (ICG R15) by differences in liver perfusion rates, hyper...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Janssen MW,Druckrey-Fiskaaen KT,Omidi L,Sliwinski G,Thiele C,Donaubauer B,Polze N,Kaisers UX,Thiery J,Wittekind C,Hauss JP,Schön MR

更新日期：2010-03-01 00:00:00

abstract：PURPOSE:Although left-sided hepatectomy, such as a left hepatectomy or left trisectionectomy with resection of the caudate lobe and extrahepatic bile duct, is used to treat hilar cholangiocarcinoma predominantly involving the left side of the hepatic hilum, it is associated with several difficult technical points. The ...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Uesaka K

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Because the biopsy specimen of extrahepatic bile duct carcinoma (EHBDC) is small and shows reactive changes, the histological distinction between malignant and benign tissue can be difficult. Recent studies reported that S100P and insulin-like growth factor II mRNA-binding protein 3 (IMP3) were not only diag...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Kawashima H,Itoh A,Ohno E,Miyahara R,Ohmiya N,Tanaka T,Shimoyama Y,Nakamura S,Ebata T,Nagino M,Goto H,Hirooka Y

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Delayed gastric emptying (DGE), a common postoperative complication of pancreaticoduodenectomy, is not considered a life-threatening complication. In the present study, we analyzed the risk factors for DGE and its impact on long-term prognosis. METHODS:We analyzed 383 patients who underwent pancreaticoduode...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Futagawa Y,Kanehira M,Furukawa K,Kitamura H,Yoshida S,Usuba T,Misawa T,Okamoto T,Yanaga K

更新日期：2017-08-01 00:00:00

abstract：INTRODUCTION:A stronger evidence level is needed to confirm the benefits and limits of laparoscopic hemihepatectomies. METHODS:Laparoscopic and open hemihepatectomies from nine European referral centers were compared after propensity score matching (right and left hemihepatectomies separately, and benign and malignant...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Cipriani F,Alzoubi M,Fuks D,Ratti F,Kawai T,Berardi G,Barkhatov L,Lainas P,Van der Poel M,Faoury M,Besselink MG,D'Hondt M,Dagher I,Edwin B,Troisi RI,Scatton O,Gayet B,Aldrighetti L,Abu Hilal M

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Gemcitabine-cisplatin (GC) and gemcitabine-oxaliplatin (GO) are the most commonly used regimens in advanced gallbladder cancer (GBC). METHODS:The data of patients with advanced GBC, treated between January 2013 and June 2015 were retrieved. A 1:1 matching without replacement was performed by using nearest n...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Ramaswamy A,Ostwal V,Pinninti R,Kannan S,Bhargava P,Nashikkar C,Mirani J,Banavali S

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND/PURPOSE:In spite of the great risk involved, the donor bile duct division procedure has not been thoroughly addressed in the literature. The purpose of this study is to show the appropriate approach to bile duct division in living donor hepatectomy. METHODS:Of 87 living donor liver surgeries, we performed b...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Takatsuki M,Eguchi S,Yamanouchi K,Hidaka M,Soyama A,Kanematsu T

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Whether systemically transplanted human adipose-derived stem cells (ADSCs) homed to the injured liver in nude mice under stress with subsequent hepatectomy (Hx) and ischemia-reperfusion (I/R) was investigated in the present study. The types of cells in the liver that were involved in the homing of ADSCs were...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Saito Y,Shimada M,Utsunomiya T,Ikemoto T,Yamada S,Morine Y,Imura S,Mori H,Arakawa Y,Kanamoto M,Iwahashi S,Takasu C

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND/PURPOSE:Living-donor pancreas transplants (LDPs) were introduced at Chiba-East National Hospital in 2004, and 12 LDPs have been performed at this institution to date. Based on the outcome of these 12 LDPs, the efficacy and safety of LDPs are herein discussed. METHODS:Twelve diabetic patients underwent LDPs;...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Kenmochi T,Asano T,Maruyama M,Saigo K,Akutsu N,Iwashita C,Ohtsuki K,Suzuki A,Miyazaki M

更新日期：2010-03-01 00:00:00

abstract：:Left hepatectomy is one of the most common types of hepatectomy. In order to perform the procedure, surgeons need to possess all the basic skills for accomplishing any liver resection. The most important points to bear in mind in relation to left hepatectomy are: (1) a precise recognition of the surgical anatomy of th...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Kobayashi A,Miyagawa S

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Aspirin is widely used for the secondary prevention of ischemic stroke and cardiovascular disease. Perioperative aspirin may decrease thrombotic morbidity, but may also increase hemorrhagic morbidity. In particular, liver resection carries risks of bleeding, leading to higher risks of hemorrhagic morbidity. ...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Monden K,Sadamori H,Hioki M,Ohno S,Saneto H,Ueki T,Yabushita K,Ono K,Sakaguchi K,Takakura N

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Intrahepatic cholangiocarcinoma had been considered a contraindication for liver transplantation because of poorer outcomes. However, incidental intrahepatic cholangiocarcinoma in the explanted liver has been reported because of the difficulty of obtaining an accurate diagnosis in cirrhotic livers on preoper...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Hara T,Eguchi S,Yoshizumi T,Akamatsu N,Kaido T,Hamada T,Takamura H,Shimamura T,Umeda Y,Shinoda M,Ogura Y,Fukumoto T,Kasahara M,Hibi T,Umeshita K,Furukawa H,Ohdan H

更新日期：2021-01-19 00:00:00

abstract：BACKGROUND/PURPOSE:Sinisan, a traditional Chinese medicine, is effective for the treatment of gastrointestinal disorders. In this study, we investigated the potential protective role of Sinisan against chronic pancreatitis (CP) in rats. METHODS:CP was induced in rats by intrapancreatic injection of trinitrobenzene sul...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Tang Y,Liao Y,Kawaguchi-Sakita N,Raut V,Fakhrejahani E,Qian N,Toi M

更新日期：2011-07-01 00:00:00

abstract：PURPOSE:We report two cases in which portal blood flow via the peribiliary vascular plexus (PBP) was clearly demonstrated using contrast-enhanced intra-operative ultrasonography (CE-IOUS). METHODS:Two patients who underwent hemihepatectomies were investigated using CE-IOUS. Before injection of the contrast medium, bot...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Uchikawa Y,Kitamura H,Miyagawa S

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:The aim was to examine the diagnostic ability of an endocytoscope system (ECS) for detecting the longitudinal extent of bile duct cancer. METHODS:We observed the surfaces of the bile duct of 28 consecutive patients undergoing biliary surgery both directly and under methylene blue staining by using an ECS. B...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Yoshikawa T,Hakamada K,Ogasawara H,Kimura N,Kudo D,Sakamoto Y,Ishido K,Toyoki Y,Morohashi S,Kijima H

更新日期：2015-01-01 00:00:00

abstract：:The extended application of living donor liver transplantation (LDLT) has revealed the problem of graft size mismatching called "small-for-size syndrome (SFSS)." The initial trials to resolve this problem involved increasing the procured graft size, from left to right, and even extending to include a right lobe graft....

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Ikegami T,Onda S,Furukawa K,Haruki K,Shirai Y,Gocho T

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Hypoxia is an important condition to promote angiogenesis that is essential to tumor progression, including pancreatic ductal adenocarcinoma (PDAC). We evaluated whether the immunohistochemistry for hypoxia inducible factor-1α (HIF-1α) was correlated with hepatic metastases in PDAC. METHODS:We examined the ...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Matsuo Y,Ding Q,Desaki R,Maemura K,Mataki Y,Shinchi H,Natsugoe S,Takao S

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND AND STUDY AIMS:Expression of the forkhead/winged helix family of transcription factor P3+ regulatory T cells (FOXP3(+) Treg), a master gene of regulatory T cells (Treg) is observed in patients with autoimmune pancreatitis (AIP). We investigated the usefulness of detection of FOXP3(+) Treg in the main duodena...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Kubota K,Kato S,Watanabe S,Fujita K,Yoneda M,Takahashi H,Inamori M,Shimamura T,Kirikoshi H,Kobayashi N,Saito S,Hisatomi K,Matsuhashi N,Nakajima A

更新日期：2011-05-01 00:00:00

abstract：:Enormous efforts have been made to establish pancreatic stem/progenitor cells as a source for regenerative medicine for the treatment of diabetes mellitus. In recent years, it has been recognized that the self-renewal of beta cells is the dominant process involved in postnatal beta-cell regeneration and expansion. Nev...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Sekine K,Taniguchi H

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Surgical indications for liver hemangioma remain unclear. METHODS:Of 510 patients undergoing surgical resection for liver hemangioma in 118 Japanese centers between 1998 and 2012, abdominal symptoms, diagnostic accuracy, and surgical outcomes were analyzed to propose size-based surgical indications. Patient...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Sakamoto Y,Kokudo N,Watadani T,Shibahara J,Yamamoto M,Yamaue H,Japanese Society of Hepato-Biliary-Pancreatic Surgery.

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Previous reports have suggested that patients with intraductal papillary mucinous neoplasm (IPMN) have a favorable prognosis after surgical resection. Thus, a variety of types of partial pancreatic resections have been advocated for treating these low-grade malignant tumors. However, the surgical outcome of ...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Nakagohri T,Kinoshita T,Konishi M,Takahashi S,Gotohda N,Kobayashi S,Kojima M,Miyauchi H,Asano T

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:The effects of ablation with various settings of powers and times using a newly developed radiofrequency (RF) ablation device, the Habib™ EndoHPB catheter, are not well known. In the present study, we examined the effects of a novel RF ablation catheter using resected fresh pig livers and evaluated the macro...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Itoi T,Isayama H,Sofuni A,Itokawa F,Tamura M,Watanabe Y,Moriyasu F,Kahaleh M,Habib N,Nagao T,Yokoyama T,Kasuya K,Kawakami H

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:We aimed to clarify the appropriate timing for performing percutaneous transhepatic gallbladder drainage (PTGBD) and cholecystectomy, and the effect of PTGBD on surgical difficulty in acute cholecystitis patients. METHODS:We retrospectively examined 46 patients who underwent laparoscopic cholecystectomy (LC...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Yamada K,Yamashita Y,Yamada T,Takeno S,Noritomi T

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Postoperative pancreatic fistula (PF) remains a major complication after pancreaticoduodenectomy (PD). We aimed to investigate the predictors of clinically relevant PF after PD. METHODS:We retrospectively analyzed the predictive factors of relevant grade B/C PF using logistic regression analysis of 100 cons...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Kosaka H,Kuroda N,Suzumura K,Asano Y,Okada T,Fujimoto J

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:For the establishment of personalized therapy, we investigated biomarkers that can contribute to the selection of adjuvant therapy for pancreatic ductal adenocarcinoma (PDAC). METHODS:Between 2005 and 2014, of 141 consecutive patients with PDAC who underwent R0 or R1 resection, 61 patients given gemcitabine...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Oba A,Ban D,Kirimura S,Akahoshi K,Mitsunori Y,Matsumura S,Ochiai T,Kudo A,Tanaka S,Minoru T

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:To investigate the potential anti-tumoral properties of propofol in pancreatic cancer and elucidate the underlying mechanisms. METHODS:The relative expression of ADAM metallopeptidase domain 8 (ADAM8) in response to hypoxia in Panc1 cells was analyzed by western blotting. The enzymatic activity was determin...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Gao Y,Yu X,Zhang F,Dai J

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND/PURPOSE:S-1 is a new oral fluoropyrimidine anticancer agent shown to be effective for pancreatic cancer. In a previous phase I trial, we evaluated the safety of S-1 combined with radiotherapy to determine the maximum tolerated dose and dose-limiting toxicity in patients with unresectable pancreatic cancer. T...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Shinchi H,Maemura K,Mataki Y,Kurahara H,Sakoda M,Ueno S,Hiraki Y,Nakajo M,Natsugoe S,Takao S

更新日期：2012-03-01 00:00:00