Genetic lineage tracing, a powerful tool to investigate the embryonic organogenesis and adult organ maintenance of the pancreas.

abstract：BACKGROUND/PURPOSE:Recent introduction of multi-detector CT (MDCT) and high-speed magnetic resonance (MR) imaging have dramatically advanced visualization and imaging technology in diagnostic and therapeutic strategy in hepatobiliary pancreatic disease. However, image diagnostics have progressed with a background of th...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Sugimoto M

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Imaging study cannot identify patients with potential low-risk for lymph node (LN) metastasis in intrahepatic cholangiocarcinoma (ICC). The purpose of this study was to identify a low-risk group for LN metastasis in ICC using preoperatively available factors. METHODS:Data from 127 consecutive patients, who ...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Yoh T,Hatano E,Seo S,Terajima H,Uchida Y,Taura K,Yasuchika K,Uemoto S

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:The objective of this study was to evaluate our new protocol for performing non-operative management for selected unstable patients under hypotensive resuscitation using improved diagnostic imaging techniques. METHODS:This retrospective study included 77 consecutive patients with blunt liver injury. They we...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Mitsusada M,Nakajima Y,Shirokawa M,Takeda T,Honda H

更新日期：2014-03-01 00:00:00

abstract：:Surgical resection is the only hope for cure in patients with pancreatic cancer. To improve the resectability and achieve better prognosis of this lethal disease, extended resection for pancreatic cancer has been applied. We have performed portal vein resection aggressively for pancreatic cancer with portal vein invas...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Yoshitomi H,Kato A,Shimizu H,Ohtsuka M,Furukawa K,Takayashiki T,Kuboki S,Takano S,Okamura D,Suzuki D,Sakai N,Kagawa S,Miyazaki M

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Previous reports have suggested that patients with intraductal papillary mucinous neoplasm (IPMN) have a favorable prognosis after surgical resection. Thus, a variety of types of partial pancreatic resections have been advocated for treating these low-grade malignant tumors. However, the surgical outcome of ...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Nakagohri T,Kinoshita T,Konishi M,Takahashi S,Gotohda N,Kobayashi S,Kojima M,Miyauchi H,Asano T

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:The National Clinical Database (NCD) in Japan is a nationwide registry that collects the data of more than 1,200,000 surgical cases annually from over 3,500 hospitals. Based on the NCD data, this study compared the perioperative outcomes of major laparoscopic liver resection (LLR) with those of major open li...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Takahara T,Wakabayashi G,Konno H,Gotoh M,Yamaue H,Yanaga K,Fujimoto J,Kaneko H,Unno M,Endo I,Seto Y,Miyata H,Miyazaki M,Yamamoto M

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Intrahepatic cholangiocarcinoma (IHC) is a rare liver malignancy with a rising incidence worldwide. Since no standard treatment has been established so far, the aim of this study was to assess the safety and efficacy of repeated liver resection and/or radiofrequency ablation (RFA) in selected cases with recu...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Kamphues C,Seehofer D,Eisele RM,Denecke T,Pratschke J,Neumann UP,Neuhaus P

更新日期：2010-07-01 00:00:00

abstract：:Congenital portosystemic shunt (CPS) is classified into type I (congenital absence of the portal vein) and type II, depending on the presence or absence of the intrahepatic portal vein. Reports still exist on cases in which psychiatric diseases or mental retardation was diagnosed or cases in which diagnosis and treatm...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Sanada Y,Mizuta K

更新日期：2018-08-01 00:00:00

abstract：:The Milan criteria (MC) have been widely accepted as an effective way of selecting patients with early-stage hepatocellular carcinoma (HCC) for curative liver transplantation (LT). However, since a substantial subset of HCC patients exists that is beyond the MC but with the potential for good outcomes after LT, severa...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Takada Y,Tohyama T,Watanabe J

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Postoperative pancreatic fistula (POPF) after distal pancreatectomy (DP) remains the most common surgical complication. We have developed a novel stump closure technique after DP using transpancreatic mattress suture with Vicryl mesh (TMV) and reported our initial findings. The purpose of this study is to ev...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Yoshida Y,Matsumoto I,Matsumoto M,Kawaguchi K,Murase T,Kamei K,Satoi S,Takebe A,Nakai T,Takeyama Y

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Peroral pancreatoscopy (POPS) using a mother-baby endoscope system is often useful for assessment of intraductal papillary mucinous neoplasm (IPMN) of the pancreas with main pancreatic duct (MPD) involvement, but is not widely used for several reasons. The aim of this study was to evaluate the usefulness of ...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Nagayoshi Y,Aso T,Ohtsuka T,Kono H,Ideno N,Igarashi H,Takahata S,Oda Y,Ito T,Tanaka M

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND/PURPOSE:To prevent or reduce hepatic complications after hepatectomy, it is important to employ preoperative predictive parameters and to determine the indications for hepatectomy. In the present study, we evaluated risk parameters in patients who underwent hepatectomy between 1994 and 2003, and selected thr...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Nanashima A,Tobinaga S,Abo T,Nonaka T,Takeshita H,Hidaka S,Sawai T,Nagayasu T

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND/PURPOSE:In spite of the great risk involved, the donor bile duct division procedure has not been thoroughly addressed in the literature. The purpose of this study is to show the appropriate approach to bile duct division in living donor hepatectomy. METHODS:Of 87 living donor liver surgeries, we performed b...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Takatsuki M,Eguchi S,Yamanouchi K,Hidaka M,Soyama A,Kanematsu T

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Acute portal pressure rise is occasionally observed during intraportal islet infusion, especially in islet autotransplantation (IAT) where tissue purification is rarely applied. In this paper we investigate factors associated with acute portal pressure rise, a known risk factor for portal vein thrombosis. M...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Kawahara T,Kin T,Shapiro AM

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Gemcitabine-cisplatin (GC) and gemcitabine-oxaliplatin (GO) are the most commonly used regimens in advanced gallbladder cancer (GBC). METHODS:The data of patients with advanced GBC, treated between January 2013 and June 2015 were retrieved. A 1:1 matching without replacement was performed by using nearest n...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Ramaswamy A,Ostwal V,Pinninti R,Kannan S,Bhargava P,Nashikkar C,Mirani J,Banavali S

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Indocyanine green (ICG) is a synthetic dye that is widely used to evaluate liver function in critically ill patients, before liver resection or after liver transplantation. Controversy still exists about the impact exerted on the ICG ratio after 15 min (ICG R15) by differences in liver perfusion rates, hyper...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Janssen MW,Druckrey-Fiskaaen KT,Omidi L,Sliwinski G,Thiele C,Donaubauer B,Polze N,Kaisers UX,Thiery J,Wittekind C,Hauss JP,Schön MR

更新日期：2010-03-01 00:00:00

abstract：:Heterogeneity is one of the essential hallmarks of malignancies. Within bulk cancer cells, a striking variability differs in biological characteristics including the proliferation rate, cell-cell interaction, metastatic tendency and even sensitivity to anticancer therapies. Such diversity makes the investigation and t...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Tanaka S

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND/PURPOSE:Sinisan, a traditional Chinese medicine, is effective for the treatment of gastrointestinal disorders. In this study, we investigated the potential protective role of Sinisan against chronic pancreatitis (CP) in rats. METHODS:CP was induced in rats by intrapancreatic injection of trinitrobenzene sul...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Tang Y,Liao Y,Kawaguchi-Sakita N,Raut V,Fakhrejahani E,Qian N,Toi M

更新日期：2011-07-01 00:00:00

abstract：:Surgical intervention and, more recently, endoscopic intervention have been performed for the treatment of malignant gastric outlet obstruction. Recently, endoscopic ultrasonography (EUS)-guided gastrojejunostomy using special devices has been established. In line with this, we have developed a novel EUS-guided double...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Itoi T,Ishii K,Tanaka R,Umeda J,Tonozuka R

更新日期：2015-01-01 00:00:00

abstract：:Highlight Although recent advances in robotic surgery have enabled more precise movements of the needle driver, a sophisticated laparoscopic suturing technique is still desired. Honda and colleagues describe the basic knowledge of and a small but useful trick for atraumatic needle driving in laparoscopic suturing, bas...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Honda G,Ome Y,Yoshida N,Kawamoto Y

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Whether systemically transplanted human adipose-derived stem cells (ADSCs) homed to the injured liver in nude mice under stress with subsequent hepatectomy (Hx) and ischemia-reperfusion (I/R) was investigated in the present study. The types of cells in the liver that were involved in the homing of ADSCs were...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Saito Y,Shimada M,Utsunomiya T,Ikemoto T,Yamada S,Morine Y,Imura S,Mori H,Arakawa Y,Kanamoto M,Iwahashi S,Takasu C

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:IgG4-sclerosing cholangitis (IgG4-SC) patients have an increased level of serum IgG4, dense infiltration of IgG4-positive plasma cells with extensive fibrosis in the bile duct wall, and a good response to steroid therapy. However, it is not easy to distinguish IgG4-SC from primary sclerosing cholangitis, pan...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Ohara H,Okazaki K,Tsubouchi H,Inui K,Kawa S,Kamisawa T,Tazuma S,Uchida K,Hirano K,Yoshida H,Nishino T,Ko SB,Mizuno N,Hamano H,Kanno A,Notohara K,Hasebe O,Nakazawa T,Nakanuma Y,Takikawa H,Research Committee of IgG4

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:The effectiveness of prophylactic antibiotics use for acute necrotizing pancreatitis has been explored and a number of systematic reviews have been published with conflicting results. The timing of antibiotics administration can be fundamental to their effectiveness, but thus far no reviews have focused on t...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Ukai T,Shikata S,Inoue M,Noguchi Y,Igarashi H,Isaji S,Mayumi T,Yoshida M,Takemura YC

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Sex is thought to play a significant role in predicting outcomes in numerous diseases. The role sex plays in acute pancreatitis (AP) remains limited. We sought to determine if sex is associated with hospitalization outcomes in this population, using a large national database. METHODS:This was a retrospectiv...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Sharma S,Weissman S,Aburayyan K,Acharya A,Aziz M,Systrom HK,Lew D,Vohra I,Feuerstein JD,Pandol SJ

更新日期：2021-01-08 00:00:00

abstract：BACKGROUND:Drip infusion cholangiography with computed tomography (DIC-CT) is a major preoperative modality used for patients undergoing laparoscopic cholecystectomy (LC). METHODS:This study included 218 patients for whom preoperative DIC-CT images were obtained prior to undergoing LC. The association between gallblad...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Nakazawa A,Akamatsu N,Miyata Y,Komagome M,Maki A,Arita J,Ishizawa T,Kaneko J,Beck Y,Hasegawa K

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Hypoxia is an important condition to promote angiogenesis that is essential to tumor progression, including pancreatic ductal adenocarcinoma (PDAC). We evaluated whether the immunohistochemistry for hypoxia inducible factor-1α (HIF-1α) was correlated with hepatic metastases in PDAC. METHODS:We examined the ...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Matsuo Y,Ding Q,Desaki R,Maemura K,Mataki Y,Shinchi H,Natsugoe S,Takao S

更新日期：2014-02-01 00:00:00

abstract：:Highlight Takenaka and colleagues report on a novel bare uncovered self-expandable metal stent developed to be compatible with only 0.025-inch guide wires. This unprecedented feature makes the delivery tip thinner and more flexible than the conventional type and useful for endoscopic bilateral stent-in-stent placement...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Takenaka M,Nakai A,Kudo M

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Since there is no reliable evidence on the safety of pancreaticoduodenectomy (PD) in chronic hepatic dysfunction (CHD) including liver cirrhosis (LC), the effects of CHD on patients undergoing PD were investigated. METHODS:This multi-institutional retrospective study analyzed 529 patients with CHD, includin...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Futagawa Y,Yanaga K,Kosuge T,Suka M,Isaji S,Hirano S,Murakami Y,Yamamoto M,Yamaue H

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVE:Roles of magnetic resonance cholangiopancreatography (MRCP), endoscopic retrograde cholangiopancreatography (ERCP), drip infusion cholangiography with computed tomography (DIC-CT), and intraoperative cholangiopancreatography (IOCP) in visualizing pancreaticobiliary anatomy for pediatric choledocal cyst (CC) o...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Saito T,Terui K,Mitsunaga T,Nakata M,Yoshida H

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND/PURPOSE:Living-donor pancreas transplants (LDPs) were introduced at Chiba-East National Hospital in 2004, and 12 LDPs have been performed at this institution to date. Based on the outcome of these 12 LDPs, the efficacy and safety of LDPs are herein discussed. METHODS:Twelve diabetic patients underwent LDPs;...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Kenmochi T,Asano T,Maruyama M,Saigo K,Akutsu N,Iwashita C,Ohtsuki K,Suzuki A,Miyazaki M

更新日期：2010-03-01 00:00:00