Recurrent intrahepatic cholangiocarcinoma: single-center experience using repeated hepatectomy and radiofrequency ablation.

abstract：BACKGROUND:Thrombospondin-1 (THBS-1), a glycoprotein, is an endogenous inhibitor of angiogenesis and tumor growth. In this study, we investigated the clinical role and mechanism of THBS-1 expression in colorectal liver metastases, focusing on the relationships between its expression and tumor growth, epithelial-mesench...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Teraoku H,Morine Y,Ikemoto T,Saito Y,Yamada S,Yoshikawa M,Takasu C,Higashijima J,Imura S,Shimada M

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Postoperative pancreatic fistula (PF) remains a major complication after pancreaticoduodenectomy (PD). We aimed to investigate the predictors of clinically relevant PF after PD. METHODS:We retrospectively analyzed the predictive factors of relevant grade B/C PF using logistic regression analysis of 100 cons...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Kosaka H,Kuroda N,Suzumura K,Asano Y,Okada T,Fujimoto J

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:To investigate the potential anti-tumoral properties of propofol in pancreatic cancer and elucidate the underlying mechanisms. METHODS:The relative expression of ADAM metallopeptidase domain 8 (ADAM8) in response to hypoxia in Panc1 cells was analyzed by western blotting. The enzymatic activity was determin...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Gao Y,Yu X,Zhang F,Dai J

更新日期：2019-06-01 00:00:00

abstract：:Although the diagnostic and severity grading criteria on the 2013 Tokyo Guidelines (TG13) are used worldwide as the primary standard for management of acute cholangitis (AC), they need to be validated through implementation and assessment in actual clinical practice. Here, we conduct a systematic review of the literat...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Kiriyama S,Kozaka K,Takada T,Strasberg SM,Pitt HA,Gabata T,Hata J,Liau KH,Miura F,Horiguchi A,Liu KH,Su CH,Wada K,Jagannath P,Itoi T,Gouma DJ,Mori Y,Mukai S,Giménez ME,Huang WS,Kim MH,Okamoto K,Belli G,Derve

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:There are no multicenter studies on the influence of diabetes duration on pancreatic transplant outcomes. Our study aimed to determine how type 1 diabetes duration influenced survival of pancreatic grafts. METHODS:The data of 8,139 patients who received pancreas transplants during 2006-2015 were extracted f...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Zhou J,Dong Y,Mei S,Gu Y,Li Z,Xiang J,Zheng H,Chen Z,Huang Z,Hu Z

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Previous reports have suggested that patients with intraductal papillary mucinous neoplasm (IPMN) have a favorable prognosis after surgical resection. Thus, a variety of types of partial pancreatic resections have been advocated for treating these low-grade malignant tumors. However, the surgical outcome of ...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Nakagohri T,Kinoshita T,Konishi M,Takahashi S,Gotohda N,Kobayashi S,Kojima M,Miyauchi H,Asano T

更新日期：2010-11-01 00:00:00

abstract：:For the resection of advanced liver tumors in which the tumor thrombus extends into the intrathoracic inferior vena cava (IVC) above the diaphragm, surgeons need very skillful techniques and much experience. However, after detachment of the line of fusion of the pericardium to the diaphragm (LFPD), the intrathoracic I...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Mizuno S,Kato H,Azumi Y,Kishiwada M,Hamada T,Usui M,Sakurai H,Tabata M,Shimpo H,Isaji S

更新日期：2010-03-01 00:00:00

abstract：:Mucobilia is a rare pathologic condition characterized by the abnormal secretion and accumulation of abundant mucus within the biliary tree. It is usually seen in association with mucin-producing hepatobiliary and pancreatic tumors. Neoplastic transformation of these tumors can range from low-grade dysplasia to invasi...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Brown MA,Sakpal SV,Chamberlain RS

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Since the publication of the Tokyo Guidelines (TG13) for the management of acute cholecystitis (AC), multidirectional studies have been published. However, epidemiological research about AC with big data was not projected. The aim of this study was to reveal the actual clinical conditions of AC. METHOD:The ...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Yokoe M,Takada T,Hwang TL,Endo I,Akazawa K,Miura F,Mayumi T,Mori R,Chen MF,Jan YY,Ker CG,Wang HP,Itoi T,Gomi H,Kiriyama S,Wada K,Yamaue H,Miyazaki M,Yamamoto M

更新日期：2017-06-01 00:00:00

abstract：AIM:The aim of this study was to evaluate the outcomes following upfront pancreaticoduodenectomy (PD) in severely jaundiced (serum bilirubin level ≥15 mg/dl) patients with malignant distal common bile duct (CBD) obstruction. BACKGROUND:Recent studies have failed to show the benefits of preoperative biliary drainage (P...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Pamecha V,Sadashiv Patil N,Kumar S,Rajendran V,Gupta S,Vasantrao Sasturkar S,Kumar Sinha P,Arora A,Agarwal N,Baghmar S

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:The National Clinical Database (NCD) in Japan is a nationwide registry that collects the data of more than 1,200,000 surgical cases annually from over 3,500 hospitals. Based on the NCD data, this study compared the perioperative outcomes of major laparoscopic liver resection (LLR) with those of major open li...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Takahara T,Wakabayashi G,Konno H,Gotoh M,Yamaue H,Yanaga K,Fujimoto J,Kaneko H,Unno M,Endo I,Seto Y,Miyata H,Miyazaki M,Yamamoto M

更新日期：2016-11-01 00:00:00

abstract：:The extended application of living donor liver transplantation (LDLT) has revealed the problem of graft size mismatching called "small-for-size syndrome (SFSS)." The initial trials to resolve this problem involved increasing the procured graft size, from left to right, and even extending to include a right lobe graft....

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Ikegami T,Onda S,Furukawa K,Haruki K,Shirai Y,Gocho T

更新日期：2020-11-01 00:00:00

abstract：:Many authors at high-volume centers all over the world have reported improved outcomes of hilar cholangiocarcinoma by several aggressive surgical approaches such as extended hepatic resection, combined vascular resection, and hepatopancreaticoduodenectomy in recent years. There has been great progress in the surgical ...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Miyazaki M,Kimura F,Shimizu H,Yoshidome H,Otuka M,Kato A,Yoshitomi H,Furukawa K,Takeuchi D,Takayashiki T,Suda K,Takano S

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:There have been no reports showing the incidence of anastomotic stenosis of continuous hepaticojejunostomy (HJ) and identifying its risk factors for patients who underwent pancreaticoduodenectomy (PD). METHOD:We retrospectively investigated 200 patients whose HJ was established by unified method, single lay...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Asano T,Natsume S,Senda Y,Sano T,Matsuo K,Kodera Y,Hara K,Ito S,Yamao K,Shimizu Y

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Hypoxia is an important condition to promote angiogenesis that is essential to tumor progression, including pancreatic ductal adenocarcinoma (PDAC). We evaluated whether the immunohistochemistry for hypoxia inducible factor-1α (HIF-1α) was correlated with hepatic metastases in PDAC. METHODS:We examined the ...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Matsuo Y,Ding Q,Desaki R,Maemura K,Mataki Y,Shinchi H,Natsugoe S,Takao S

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Stent-stone complex (SSC) formation is one of the complications of endoscopic biliary stent placement. This study aimed to clarify the clinical characteristics and risk factors for SSC formation following plastic stent (PS) placement in patients with common bile duct (CBD) stones. METHODS:We retrospectively...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Kaneko J,Kawata K,Watanabe S,Chida T,Matsushita M,Suda T,Kobayashi Y

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Sex is thought to play a significant role in predicting outcomes in numerous diseases. The role sex plays in acute pancreatitis (AP) remains limited. We sought to determine if sex is associated with hospitalization outcomes in this population, using a large national database. METHODS:This was a retrospectiv...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Sharma S,Weissman S,Aburayyan K,Acharya A,Aziz M,Systrom HK,Lew D,Vohra I,Feuerstein JD,Pandol SJ

更新日期：2021-01-08 00:00:00

abstract：BACKGROUND:Postoperative pancreatic fistula (POPF) after distal pancreatectomy (DP) remains the most common surgical complication. We have developed a novel stump closure technique after DP using transpancreatic mattress suture with Vicryl mesh (TMV) and reported our initial findings. The purpose of this study is to ev...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Yoshida Y,Matsumoto I,Matsumoto M,Kawaguchi K,Murase T,Kamei K,Satoi S,Takebe A,Nakai T,Takeyama Y

更新日期：2019-11-01 00:00:00

abstract：:Enormous efforts have been made to establish pancreatic stem/progenitor cells as a source for regenerative medicine for the treatment of diabetes mellitus. In recent years, it has been recognized that the self-renewal of beta cells is the dominant process involved in postnatal beta-cell regeneration and expansion. Nev...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Sekine K,Taniguchi H

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:We aimed to clarify the appropriate timing for performing percutaneous transhepatic gallbladder drainage (PTGBD) and cholecystectomy, and the effect of PTGBD on surgical difficulty in acute cholecystitis patients. METHODS:We retrospectively examined 46 patients who underwent laparoscopic cholecystectomy (LC...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Yamada K,Yamashita Y,Yamada T,Takeno S,Noritomi T

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Anoikis is a specialized cell apoptosis triggered by loss of cell adhesion. Acquisition of anoikis resistance is a key cancer hallmark that has been associated with metastasis of human malignancies. Cholangiocarcinoma (CCA) is a highly metastatic cancer of the bile duct, in which mechanisms underlying its re...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Huyen NT,Prachayasittikul V,Chan-On W

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:The aim was to examine the diagnostic ability of an endocytoscope system (ECS) for detecting the longitudinal extent of bile duct cancer. METHODS:We observed the surfaces of the bile duct of 28 consecutive patients undergoing biliary surgery both directly and under methylene blue staining by using an ECS. B...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Yoshikawa T,Hakamada K,Ogasawara H,Kimura N,Kudo D,Sakamoto Y,Ishido K,Toyoki Y,Morohashi S,Kijima H

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND AND STUDY AIMS:Expression of the forkhead/winged helix family of transcription factor P3+ regulatory T cells (FOXP3(+) Treg), a master gene of regulatory T cells (Treg) is observed in patients with autoimmune pancreatitis (AIP). We investigated the usefulness of detection of FOXP3(+) Treg in the main duodena...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Kubota K,Kato S,Watanabe S,Fujita K,Yoneda M,Takahashi H,Inamori M,Shimamura T,Kirikoshi H,Kobayashi N,Saito S,Hisatomi K,Matsuhashi N,Nakajima A

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND/PURPOSE:To describe surgical techniques and results of right hepatic lobectomy (RHL) with thoracotomy. METHODS:This procedure consists of laparotomy and thoracotomy, cholecystectomy, division of the right hepatic artery and right portal vein, mobilization of the liver, division of the right hepatic vein, tr...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Kubota K

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND/PURPOSE:To prevent or reduce hepatic complications after hepatectomy, it is important to employ preoperative predictive parameters and to determine the indications for hepatectomy. In the present study, we evaluated risk parameters in patients who underwent hepatectomy between 1994 and 2003, and selected thr...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Nanashima A,Tobinaga S,Abo T,Nonaka T,Takeshita H,Hidaka S,Sawai T,Nagayasu T

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:IgG4-sclerosing cholangitis (IgG4-SC) patients have an increased level of serum IgG4, dense infiltration of IgG4-positive plasma cells with extensive fibrosis in the bile duct wall, and a good response to steroid therapy. However, it is not easy to distinguish IgG4-SC from primary sclerosing cholangitis, pan...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Ohara H,Okazaki K,Tsubouchi H,Inui K,Kawa S,Kamisawa T,Tazuma S,Uchida K,Hirano K,Yoshida H,Nishino T,Ko SB,Mizuno N,Hamano H,Kanno A,Notohara K,Hasebe O,Nakazawa T,Nakanuma Y,Takikawa H,Research Committee of IgG4

更新日期：2012-09-01 00:00:00

abstract：:Borderline resectable (BR) pancreatic cancer involves the portal vein and/or superior mesenteric vein (PV/SMV), major arteries including the superior mesenteric artery (SMA) or common hepatic artery (CHA), and sometimes includes the involvement of the celiac axis. We herein describe tips and tricks for a surgical tech...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Hirono S,Yamaue H

更新日期：2015-02-01 00:00:00

abstract：:Since the introduction of endoscopic sphincterotomy, stone clearance of the bile duct can be achieved by conventional endoscopic means in up to 90% of patients with stone disease. Several endoscopic therapies for difficult bile duct stones have been introduced. Laser therapy for stone fragmentation under direct visual...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Seelhoff A,Schumacher B,Neuhaus H

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Tokyo Guideline 2013 (TG13) proposed three drainage techniques for the treatment of acute cholecystitis. We evaluated the clinical efficacy and adverse events between percutaneous transhepatic intervention (PTGBI) including percutaneous transhepatic gallbladder drainage (PTGBD) and percutaneous transhepatic ...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Itoi T,Takada T,Hwang TL,Endo I,Akazawa K,Miura F,Chen MF,Jan YY,Ker CG,Wang HP,Gomi H,Yokoe M,Kiriyama S,Wada K,Yamaue H,Miyazaki M,Yamamoto M

更新日期：2017-06-01 00:00:00

abstract：:Surgical resection is the only hope for cure in patients with pancreatic cancer. To improve the resectability and achieve better prognosis of this lethal disease, extended resection for pancreatic cancer has been applied. We have performed portal vein resection aggressively for pancreatic cancer with portal vein invas...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Yoshitomi H,Kato A,Shimizu H,Ohtsuka M,Furukawa K,Takayashiki T,Kuboki S,Takano S,Okamura D,Suzuki D,Sakai N,Kagawa S,Miyazaki M

更新日期：2014-09-01 00:00:00