Abstract:
BACKGROUND:Sex is thought to play a significant role in predicting outcomes in numerous diseases. The role sex plays in acute pancreatitis (AP) remains limited. We sought to determine if sex is associated with hospitalization outcomes in this population, using a large national database. METHODS:This was a retrospective study of adult patients with AP utilizing the 2016 and 2017 National Inpatient Sample via ICD-10 codes. The clinical courses of females were compared to that of males. The primary outcome was all-cause inpatient mortality. Secondary outcomes, including healthcare utilization, were assessed. Statistical analyses were performed using STATA, version 16.1. RESULTS:Of the 553 480 adult patients hospitalized with AP; 25.3% had AP secondary to alcohol (61.4% male, 38.6% female) and 17.44% secondary to gallstones (48.6% male, 51.4% female). Females were significantly older than males (52.81 years vs 50.97 years, P < .01). Females had a significantly lower likelihood of mortality (aOR: 0.69), shock (aOR: 0.64), sepsis (aOR: 0.70), acute kidney injury (aOR 0.66), intensive care unit admission (aOR 0.53), and pancreatic drainage (aOR 0.61) as compared to males (all with P < .01). There was no significant difference between females and males with regards to mean length of stay and hospitalization charges and costs. CONCLUSIONS:In this large cohort of patients admitted for AP, despite being significantly older, we found that females had significantly improved clinical outcomes, including lower mortality, compared to males. Further prospective studies are needed to accurately understand these differences to guide clinical practice.
journal_name
J Hepatobiliary Pancreat Scijournal_title
Journal of hepato-biliary-pancreatic sciencesauthors
Sharma S,Weissman S,Aburayyan K,Acharya A,Aziz M,Systrom HK,Lew D,Vohra I,Feuerstein JD,Pandol SJdoi
10.1002/jhbp.890subject
Has Abstractpub_date
2021-01-08 00:00:00eissn
1868-6974issn
1868-6982pub_type
杂志文章abstract:PURPOSE:We report two cases in which portal blood flow via the peribiliary vascular plexus (PBP) was clearly demonstrated using contrast-enhanced intra-operative ultrasonography (CE-IOUS). METHODS:Two patients who underwent hemihepatectomies were investigated using CE-IOUS. Before injection of the contrast medium, bot...
journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章
doi:10.1007/s00534-011-0380-y
更新日期:2011-07-01 00:00:00
abstract:BACKGROUND:Stent-stone complex (SSC) formation is one of the complications of endoscopic biliary stent placement. This study aimed to clarify the clinical characteristics and risk factors for SSC formation following plastic stent (PS) placement in patients with common bile duct (CBD) stones. METHODS:We retrospectively...
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journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章,多中心研究
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更新日期:2015-10-01 00:00:00
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journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章,评审
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journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章
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journal_title:Journal of hepato-biliary-pancreatic sciences
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journal_title:Journal of hepato-biliary-pancreatic sciences
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journal_title:Journal of hepato-biliary-pancreatic sciences
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更新日期:2016-09-01 00:00:00
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journal_title:Journal of hepato-biliary-pancreatic sciences
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更新日期:2020-03-01 00:00:00
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journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章,评审
doi:10.1002/jhbp.148
更新日期:2015-01-01 00:00:00
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journal_title:Journal of hepato-biliary-pancreatic sciences
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journal_title:Journal of hepato-biliary-pancreatic sciences
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更新日期:2018-08-01 00:00:00
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journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 评论,杂志文章
doi:10.1002/jhbp.294
更新日期:2015-12-01 00:00:00
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journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章
doi:10.1007/s00534-012-0581-z
更新日期:2013-04-01 00:00:00
abstract::Since the publication of the Tokyo Guidelines in 2007 and their revision in 2013, appropriate management for acute cholecystitis has been more clearly established. Since the last revision, several manuscripts, especially for alternative endoscopic techniques, have been reported; therefore, additional evaluation and re...
journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 信件,评审
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更新日期:2018-01-01 00:00:00
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journal_title:Journal of hepato-biliary-pancreatic sciences
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更新日期:2014-08-01 00:00:00
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journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章,评审
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更新日期:2011-05-01 00:00:00
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journal_title:Journal of hepato-biliary-pancreatic sciences
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更新日期:2015-02-01 00:00:00
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journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章
doi:10.1002/jhbp.147
更新日期:2014-12-01 00:00:00
abstract:BACKGROUND:Surgical indications for liver hemangioma remain unclear. METHODS:Of 510 patients undergoing surgical resection for liver hemangioma in 118 Japanese centers between 1998 and 2012, abdominal symptoms, diagnostic accuracy, and surgical outcomes were analyzed to propose size-based surgical indications. Patient...
journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章
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更新日期:2017-07-01 00:00:00
abstract:BACKGROUND:Previous reports have suggested that patients with intraductal papillary mucinous neoplasm (IPMN) have a favorable prognosis after surgical resection. Thus, a variety of types of partial pancreatic resections have been advocated for treating these low-grade malignant tumors. However, the surgical outcome of ...
journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章,多中心研究
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更新日期:2010-11-01 00:00:00
abstract:BACKGROUND:The National Clinical Database (NCD) in Japan is a nationwide registry that collects the data of more than 1,200,000 surgical cases annually from over 3,500 hospitals. Based on the NCD data, this study compared the perioperative outcomes of major laparoscopic liver resection (LLR) with those of major open li...
journal_title:Journal of hepato-biliary-pancreatic sciences
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更新日期:2016-11-01 00:00:00
abstract::Right hepatectomy for hepatocellular carcinoma is the most common major operation in liver surgery; therefore, liver surgeons should know the fundamental surgical concept and techniques of the Glissonean pedicle approach. A J-shaped or reversed T laparotomy is performed in the right subcostal area. The Glissonean pedi...
journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章
doi:10.1007/s00534-011-0445-y
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND/PURPOSE:Ampulla of Vater (AoV) carcinoma is a rare tumor that accounts for approximately 0.2% of gastrointestinal malignancies. There are no clinical guidelines concerning the treatment of AoV carcinoma. This study aimed to investigate the effectiveness of adjuvant treatment in AoV carcinoma following curati...
journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章
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更新日期:2020-10-01 00:00:00
abstract:BACKGROUND:To investigate the potential anti-tumoral properties of propofol in pancreatic cancer and elucidate the underlying mechanisms. METHODS:The relative expression of ADAM metallopeptidase domain 8 (ADAM8) in response to hypoxia in Panc1 cells was analyzed by western blotting. The enzymatic activity was determin...
journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章
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更新日期:2019-06-01 00:00:00