Abstract:
BACKGROUND:Although intraoperative peritoneal lavage is often performed routinely with the aim of reducing peritoneal contamination, little evidence of lavage benefits in elective liver resection without bile duct resection is available. We addressed the issue with a randomized clinical trial. METHODS:We prospectively and randomly assigned consecutive patients undergoing liver resection to a lavage group or a non-lavage group. Peritoneal lavage was performed at the end of operation for patients in the lavage group. The primary endpoint was the rate of surgical site infection. RESULTS:Ninety-six patients were assigned to the lavage group and 97 to the non-lavage group. When superficial/deep incisional infection and organ/space infection were considered together, no significant difference in surgical site infection rate was evident between lavage (21.9%) and non-lavage groups (13.4%, P = 0.135). However, organ/space infection was significantly more frequent in the lavage group (16.7%) than the non-lavage group (7.2%, P = 0.048). Peritoneal lavage was identified as a risk factor for organ/space infection by multivariate analysis (relative risk, 2.977; confidence interval, 1.094 to 8.100; P = 0.033). CONCLUSION:Intraoperative peritoneal lavage does not reduce overall incidence of surgical site infection and may increase risk of organ/space infection.
journal_name
J Hepatobiliary Pancreat Scijournal_title
Journal of hepato-biliary-pancreatic sciencesauthors
Tanaka K,Matsuo K,Kawaguchi D,Murakami T,Hiroshima Y,Hirano A,Sato S,Endo I,Taguri M,Koda Kdoi
10.1002/jhbp.222subject
Has Abstractpub_date
2015-06-01 00:00:00pages
446-53issue
6eissn
1868-6974issn
1868-6982journal_volume
22pub_type
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journal_title:Journal of hepato-biliary-pancreatic sciences
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journal_title:Journal of hepato-biliary-pancreatic sciences
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journal_title:Journal of hepato-biliary-pancreatic sciences
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journal_title:Journal of hepato-biliary-pancreatic sciences
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journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章,评审
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journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章
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journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章,多中心研究
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更新日期:2017-06-01 00:00:00
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journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 信件,评审
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更新日期:2018-01-01 00:00:00
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journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章,meta分析,评审
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journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章
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更新日期:2010-03-01 00:00:00