Outcomes of pancreaticoduodenectomy in patients with chronic hepatic dysfunction including liver cirrhosis: results of a retrospective multicenter study by the Japanese Society of Hepato-Biliary-Pancreatic Surgery.

abstract：BACKGROUND/PURPOSE:Ampulla of Vater (AoV) carcinoma is a rare tumor that accounts for approximately 0.2% of gastrointestinal malignancies. There are no clinical guidelines concerning the treatment of AoV carcinoma. This study aimed to investigate the effectiveness of adjuvant treatment in AoV carcinoma following curati...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Kim HS,Jang JY,Yoon YS,Park SJ,Kwon W,Kim SW,Han HS,Han SS,Park JS,Yoon DS

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND/PURPOSE:Living-donor pancreas transplants (LDPs) were introduced at Chiba-East National Hospital in 2004, and 12 LDPs have been performed at this institution to date. Based on the outcome of these 12 LDPs, the efficacy and safety of LDPs are herein discussed. METHODS:Twelve diabetic patients underwent LDPs;...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Kenmochi T,Asano T,Maruyama M,Saigo K,Akutsu N,Iwashita C,Ohtsuki K,Suzuki A,Miyazaki M

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Since the publication of the Tokyo Guidelines (TG13) for the management of acute cholecystitis (AC), multidirectional studies have been published. However, epidemiological research about AC with big data was not projected. The aim of this study was to reveal the actual clinical conditions of AC. METHOD:The ...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Yokoe M,Takada T,Hwang TL,Endo I,Akazawa K,Miura F,Mayumi T,Mori R,Chen MF,Jan YY,Ker CG,Wang HP,Itoi T,Gomi H,Kiriyama S,Wada K,Yamaue H,Miyazaki M,Yamamoto M

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:To investigate the potential anti-tumoral properties of propofol in pancreatic cancer and elucidate the underlying mechanisms. METHODS:The relative expression of ADAM metallopeptidase domain 8 (ADAM8) in response to hypoxia in Panc1 cells was analyzed by western blotting. The enzymatic activity was determin...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Gao Y,Yu X,Zhang F,Dai J

更新日期：2019-06-01 00:00:00

abstract：:Surgical intervention and, more recently, endoscopic intervention have been performed for the treatment of malignant gastric outlet obstruction. Recently, endoscopic ultrasonography (EUS)-guided gastrojejunostomy using special devices has been established. In line with this, we have developed a novel EUS-guided double...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Itoi T,Ishii K,Tanaka R,Umeda J,Tonozuka R

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND/PURPOSE:The purpose of the present study was to assess long-term outcomes following liver resection for colorectal liver metastases (CRLM) with concurrent extrahepatic disease and to identify the preoperative prognostic factors for selection of operative candidates. METHODS:In this retrospective, multi-inst...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Sawada Y,Sahara K,Endo I,Sakamoto K,Honda G,Beppu T,Kotake K,Yamamoto M,Takahashi K,Hasegawa K,Itabashi M,Hashiguchi Y,Kotera Y,Kobayashi S,Yamaguchi T,Tabuchi K,Kobayashi H,Yamaguchi K,Morita S,Natsume S,Miyazaki

更新日期：2020-11-01 00:00:00

abstract：:There is a high risk of anastomotic leakage following pancreaticojejunostomy after pancreaticoduodenectomy or middle pancreatectomy in patients with a normal soft pancreas because of the abundant exocrine function. Therefore, pancreaticojejunostomy is generally performed using a stent tube (stented method). However, p...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Hatori T

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:We investigated the aberrant expression of the STAT family in humans and liver fluke (Opisthorchis viverrini, Ov)-induced hamster cholangiocarcinoma (CCA) tissues. METHODS:The expression and phosphorylation of STAT1, STAT2, STAT3, STAT4, STAT5a, STAT5b and STAT6 in human hamster CCA tissues were immunohisto...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Dokduang H,Techasen A,Namwat N,Khuntikeo N,Pairojkul C,Murakami Y,Loilome W,Yongvanit P

更新日期：2014-10-01 00:00:00

abstract：PURPOSE:Although left-sided hepatectomy, such as a left hepatectomy or left trisectionectomy with resection of the caudate lobe and extrahepatic bile duct, is used to treat hilar cholangiocarcinoma predominantly involving the left side of the hepatic hilum, it is associated with several difficult technical points. The ...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Uesaka K

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND/PURPOSE:To prevent or reduce hepatic complications after hepatectomy, it is important to employ preoperative predictive parameters and to determine the indications for hepatectomy. In the present study, we evaluated risk parameters in patients who underwent hepatectomy between 1994 and 2003, and selected thr...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Nanashima A,Tobinaga S,Abo T,Nonaka T,Takeshita H,Hidaka S,Sawai T,Nagayasu T

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:The influence of donor-recipient gender mismatch on outcomes after liver transplantation (LT) is controversial. The aim of this study was to evaluate the effect of donor and recipient gender discordance on graft survival. METHODS:All patients who underwent primary LT from 1994-2012 at a single-center were i...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Croome KP,Segal D,Hernandez-Alejandro R,Adams PC,Thomson A,Chandok N

更新日期：2014-04-01 00:00:00

abstract：:In the EASL and AASLD guidelines, hepatic resection (HR) is considered the first option for patients in stage 0 (very early HCC). This statement was not based on randomized controlled trials (RCTs) versus other therapies, but on the oncological assumption that HR is the better procedure for obtaining complete tumor ab...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Livraghi T

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The present study retrospectively analyzed the clinical impact of endoscopic papillectomy on the selection of a treatment strategy for patients with benign-malignant borderline lesions of the major duodenal papilla. PATIENTS AND METHODS:Between November 1995 and July 2009, 28 patients were selec...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Harano M,Ryozawa S,Iwano H,Taba K,Sen-Yo M,Sakaida I

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Because the biopsy specimen of extrahepatic bile duct carcinoma (EHBDC) is small and shows reactive changes, the histological distinction between malignant and benign tissue can be difficult. Recent studies reported that S100P and insulin-like growth factor II mRNA-binding protein 3 (IMP3) were not only diag...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Kawashima H,Itoh A,Ohno E,Miyahara R,Ohmiya N,Tanaka T,Shimoyama Y,Nakamura S,Ebata T,Nagino M,Goto H,Hirooka Y

更新日期：2013-04-01 00:00:00

abstract：:Surgical resection, considered the optimal treatment of biliary papillomatosis, often remains incomplete due to high risk of recurrence in view of positive margins or recurrence on the remnant bile duct because of its multifocality. Resection of the whole biliary tree by liver transplantation and duodenopancreatectomy...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Vibert E,Dokmak S,Belghiti J

更新日期：2010-05-01 00:00:00

abstract：:The extended application of living donor liver transplantation (LDLT) has revealed the problem of graft size mismatching called "small-for-size syndrome (SFSS)." The initial trials to resolve this problem involved increasing the procured graft size, from left to right, and even extending to include a right lobe graft....

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Ikegami T,Onda S,Furukawa K,Haruki K,Shirai Y,Gocho T

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Imaging study cannot identify patients with potential low-risk for lymph node (LN) metastasis in intrahepatic cholangiocarcinoma (ICC). The purpose of this study was to identify a low-risk group for LN metastasis in ICC using preoperatively available factors. METHODS:Data from 127 consecutive patients, who ...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Yoh T,Hatano E,Seo S,Terajima H,Uchida Y,Taura K,Yasuchika K,Uemoto S

更新日期：2018-06-01 00:00:00

abstract：:The Milan criteria (MC) have been widely accepted as an effective way of selecting patients with early-stage hepatocellular carcinoma (HCC) for curative liver transplantation (LT). However, since a substantial subset of HCC patients exists that is beyond the MC but with the potential for good outcomes after LT, severa...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Takada Y,Tohyama T,Watanabe J

更新日期：2015-04-01 00:00:00

abstract：:Segmentectomy is anatomical resection of segments based on the classification of Couinaud. This procedure is performed mainly for hepatocellular carcinoma. Invasion of portal vein and intrahepatic metastases often occur with hepatocellular carcinoma. Thus, it is desirable to perform anatomical resection of the cancer-...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Yoshida H,Katayose Y,Rikiyama T,Motoi F,Onogawa T,Egawa S,Unno M

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:The Japanese Society of Hepato-Biliary-Pancreatic Surgery launched the clinical practice guidelines for the management of biliary tract cancers (cholangiocarcinoma, gallbladder cancer, and ampullary cancer) in 2007, then published the 2nd version in 2014. METHODS:In this 3rd version, clinical questions (CQs...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Nagino M,Hirano S,Yoshitomi H,Aoki T,Uesaka K,Unno M,Ebata T,Konishi M,Sano K,Shimada K,Shimizu H,Higuchi R,Wakai T,Isayama H,Okusaka T,Tsuyuguchi T,Hirooka Y,Furuse J,Maguchi H,Suzuki K,Yamazaki H,Kijima H,Ya

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Acute portal pressure rise is occasionally observed during intraportal islet infusion, especially in islet autotransplantation (IAT) where tissue purification is rarely applied. In this paper we investigate factors associated with acute portal pressure rise, a known risk factor for portal vein thrombosis. M...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Kawahara T,Kin T,Shapiro AM

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:The effects of ablation with various settings of powers and times using a newly developed radiofrequency (RF) ablation device, the Habib™ EndoHPB catheter, are not well known. In the present study, we examined the effects of a novel RF ablation catheter using resected fresh pig livers and evaluated the macro...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Itoi T,Isayama H,Sofuni A,Itokawa F,Tamura M,Watanabe Y,Moriyasu F,Kahaleh M,Habib N,Nagao T,Yokoyama T,Kasuya K,Kawakami H

更新日期：2012-09-01 00:00:00

abstract：:Since the publication of the Tokyo Guidelines in 2007 and their revision in 2013, appropriate management for acute cholecystitis has been more clearly established. Since the last revision, several manuscripts, especially for alternative endoscopic techniques, have been reported; therefore, additional evaluation and re...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Mori Y,Itoi T,Baron TH,Takada T,Strasberg SM,Pitt HA,Ukai T,Shikata S,Noguchi Y,Teoh AYB,Kim MH,Asbun HJ,Endo I,Yokoe M,Miura F,Okamoto K,Suzuki K,Umezawa A,Iwashita Y,Hibi T,Wakabayashi G,Han HS,Yoon YS,Cho

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND AND STUDY AIMS:Expression of the forkhead/winged helix family of transcription factor P3+ regulatory T cells (FOXP3(+) Treg), a master gene of regulatory T cells (Treg) is observed in patients with autoimmune pancreatitis (AIP). We investigated the usefulness of detection of FOXP3(+) Treg in the main duodena...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Kubota K,Kato S,Watanabe S,Fujita K,Yoneda M,Takahashi H,Inamori M,Shimamura T,Kirikoshi H,Kobayashi N,Saito S,Hisatomi K,Matsuhashi N,Nakajima A

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Delayed gastric emptying (DGE), a common postoperative complication of pancreaticoduodenectomy, is not considered a life-threatening complication. In the present study, we analyzed the risk factors for DGE and its impact on long-term prognosis. METHODS:We analyzed 383 patients who underwent pancreaticoduode...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Futagawa Y,Kanehira M,Furukawa K,Kitamura H,Yoshida S,Usuba T,Misawa T,Okamoto T,Yanaga K

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Latent pancreatic fistula (LPF) is difficult to diagnose during the early postoperative phase because of initially normal drain fluid amylase (DFA) levels. The present study investigated the clinical significance and risk factors of LPF after pancreatoduodenectomy. METHODS:A total of 662 patients who underw...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Ohgi K,Yamamoto Y,Sugiura T,Okamura Y,Ito T,Ashida R,Uesaka K

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND/PURPOSE:S-1 is a new oral fluoropyrimidine anticancer agent shown to be effective for pancreatic cancer. In a previous phase I trial, we evaluated the safety of S-1 combined with radiotherapy to determine the maximum tolerated dose and dose-limiting toxicity in patients with unresectable pancreatic cancer. T...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Shinchi H,Maemura K,Mataki Y,Kurahara H,Sakoda M,Ueno S,Hiraki Y,Nakajo M,Natsugoe S,Takao S

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Whether systemically transplanted human adipose-derived stem cells (ADSCs) homed to the injured liver in nude mice under stress with subsequent hepatectomy (Hx) and ischemia-reperfusion (I/R) was investigated in the present study. The types of cells in the liver that were involved in the homing of ADSCs were...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Saito Y,Shimada M,Utsunomiya T,Ikemoto T,Yamada S,Morine Y,Imura S,Mori H,Arakawa Y,Kanamoto M,Iwahashi S,Takasu C

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Gemcitabine-cisplatin (GC) and gemcitabine-oxaliplatin (GO) are the most commonly used regimens in advanced gallbladder cancer (GBC). METHODS:The data of patients with advanced GBC, treated between January 2013 and June 2015 were retrieved. A 1:1 matching without replacement was performed by using nearest n...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Ramaswamy A,Ostwal V,Pinninti R,Kannan S,Bhargava P,Nashikkar C,Mirani J,Banavali S

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Postoperative pancreatic fistula (PF) remains a major complication after pancreaticoduodenectomy (PD). We aimed to investigate the predictors of clinically relevant PF after PD. METHODS:We retrospectively analyzed the predictive factors of relevant grade B/C PF using logistic regression analysis of 100 cons...

journal_title：Journal of hepato-biliary-pancreatic sciences

authors： Kosaka H,Kuroda N,Suzumura K,Asano Y,Okada T,Fujimoto J

更新日期：2014-02-01 00:00:00