Abstract:
:Surgical resection, considered the optimal treatment of biliary papillomatosis, often remains incomplete due to high risk of recurrence in view of positive margins or recurrence on the remnant bile duct because of its multifocality. Resection of the whole biliary tree by liver transplantation and duodenopancreatectomy can be regarded as the only curative treatment. However, this approach has resulted in unfavorable results in patients with advanced tumor invasion and/or positive lymph nodes. For the majority of biliary tumors, preoperative assessment is often insufficient. Therefore, we advocate initial partial resection as a first step to eliminate both advanced tumor invasion and/or positive lymph nodes on definitive analysis of the specimen. We propose the strategy of initial resection for selecting the patients who would actually benefit from liver transplantation.
journal_name
J Hepatobiliary Pancreat Scijournal_title
Journal of hepato-biliary-pancreatic sciencesauthors
Vibert E,Dokmak S,Belghiti Jdoi
10.1007/s00534-009-0151-1subject
Has Abstractpub_date
2010-05-01 00:00:00pages
241-5issue
3eissn
1868-6974issn
1868-6982journal_volume
17pub_type
杂志文章abstract:BACKGROUND:Because the biopsy specimen of extrahepatic bile duct carcinoma (EHBDC) is small and shows reactive changes, the histological distinction between malignant and benign tissue can be difficult. Recent studies reported that S100P and insulin-like growth factor II mRNA-binding protein 3 (IMP3) were not only diag...
journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章
doi:10.1007/s00534-012-0581-z
更新日期:2013-04-01 00:00:00
abstract:BACKGROUND/PURPOSE:Hilar cholangiocarcinoma and intrahepatic cholangiocarcinoma involving the hepatic hilus are defined as "perihilar cholangiocarcinoma". The principle of surgical treatment is hemi-hepatectomy or trisectionectomy of the liver, caudate lobectomy, and resection of the extrahepatic bile duct for complete...
journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章
doi:10.1007/s00534-009-0206-3
更新日期:2010-07-01 00:00:00
abstract:BACKGROUND:Imaging study cannot identify patients with potential low-risk for lymph node (LN) metastasis in intrahepatic cholangiocarcinoma (ICC). The purpose of this study was to identify a low-risk group for LN metastasis in ICC using preoperatively available factors. METHODS:Data from 127 consecutive patients, who ...
journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章
doi:10.1002/jhbp.552
更新日期:2018-06-01 00:00:00
abstract::Until now, there have been no practical clinical guidelines for congenital biliary dilatation (CBD). In this review article, the Japanese Study Group on Congenital Biliary Dilatation (JSCBD) propose to establish clinical practice guidelines for CBD. Because the evidence-based literature is relatively small, we decided...
journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 信件,评审
doi:10.1002/jhbp.415
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Latent pancreatic fistula (LPF) is difficult to diagnose during the early postoperative phase because of initially normal drain fluid amylase (DFA) levels. The present study investigated the clinical significance and risk factors of LPF after pancreatoduodenectomy. METHODS:A total of 662 patients who underw...
journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章
doi:10.1002/jhbp.820
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:Drip infusion cholangiography with computed tomography (DIC-CT) is a major preoperative modality used for patients undergoing laparoscopic cholecystectomy (LC). METHODS:This study included 218 patients for whom preoperative DIC-CT images were obtained prior to undergoing LC. The association between gallblad...
journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章
doi:10.1002/jhbp.718
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND:Although intraoperative peritoneal lavage is often performed routinely with the aim of reducing peritoneal contamination, little evidence of lavage benefits in elective liver resection without bile duct resection is available. We addressed the issue with a randomized clinical trial. METHODS:We prospectively...
journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章,随机对照试验
doi:10.1002/jhbp.222
更新日期:2015-06-01 00:00:00
abstract:BACKGROUND:Gemcitabine-cisplatin (GC) and gemcitabine-oxaliplatin (GO) are the most commonly used regimens in advanced gallbladder cancer (GBC). METHODS:The data of patients with advanced GBC, treated between January 2013 and June 2015 were retrieved. A 1:1 matching without replacement was performed by using nearest n...
journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章
doi:10.1002/jhbp.439
更新日期:2017-05-01 00:00:00
abstract::Highlight Although recent advances in robotic surgery have enabled more precise movements of the needle driver, a sophisticated laparoscopic suturing technique is still desired. Honda and colleagues describe the basic knowledge of and a small but useful trick for atraumatic needle driving in laparoscopic suturing, bas...
journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章
doi:10.1002/jhbp.814
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND/PURPOSE:Sinisan, a traditional Chinese medicine, is effective for the treatment of gastrointestinal disorders. In this study, we investigated the potential protective role of Sinisan against chronic pancreatitis (CP) in rats. METHODS:CP was induced in rats by intrapancreatic injection of trinitrobenzene sul...
journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章
doi:10.1007/s00534-010-0368-z
更新日期:2011-07-01 00:00:00
abstract::Mucobilia is a rare pathologic condition characterized by the abnormal secretion and accumulation of abundant mucus within the biliary tree. It is usually seen in association with mucin-producing hepatobiliary and pancreatic tumors. Neoplastic transformation of these tumors can range from low-grade dysplasia to invasi...
journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章,评审
doi:10.1007/s00534-009-0150-2
更新日期:2010-05-01 00:00:00
abstract:BACKGROUND:An aberrant right posterior sectoral hepatic duct (PHD) draining into extrahepatic bile duct, gallbladder or cystic duct directly is a common and critical anomaly during cholecystectomy. This study aimed to investigate the frequency of aberrant PHD and describe why PHD is critical. METHODS:In 753 consecutiv...
journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章
doi:10.1002/jhbp.252
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:Peroral pancreatoscopy (POPS) using a mother-baby endoscope system is often useful for assessment of intraductal papillary mucinous neoplasm (IPMN) of the pancreas with main pancreatic duct (MPD) involvement, but is not widely used for several reasons. The aim of this study was to evaluate the usefulness of ...
journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章
doi:10.1002/jhbp.44
更新日期:2014-06-01 00:00:00
abstract:BACKGROUND:Thrombospondin-1 (THBS-1), a glycoprotein, is an endogenous inhibitor of angiogenesis and tumor growth. In this study, we investigated the clinical role and mechanism of THBS-1 expression in colorectal liver metastases, focusing on the relationships between its expression and tumor growth, epithelial-mesench...
journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章
doi:10.1002/jhbp.376
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND AND STUDY AIMS:Expression of the forkhead/winged helix family of transcription factor P3+ regulatory T cells (FOXP3(+) Treg), a master gene of regulatory T cells (Treg) is observed in patients with autoimmune pancreatitis (AIP). We investigated the usefulness of detection of FOXP3(+) Treg in the main duodena...
journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章
doi:10.1007/s00534-010-0359-0
更新日期:2011-05-01 00:00:00
abstract::Revealing the mechanism of adult organ maintenance and regeneration after injury is fundamental to our understanding of the pathogenesis of diseases. Considering the results of pulse and chase experiments using inducible insulin-Cre or Elastase-Cre, and more recently HNF1b-Cre, adult pancreatic cells (beta, acinar, an...
journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章,评审
doi:10.1007/s00534-010-0307-z
更新日期:2011-01-01 00:00:00
abstract::Lactate measurements have proven utility as a triage tool, therapeutic guide, and prognostic indicator, with broad use in Acute Care and transplantation. Its value in guiding therapy and predicting outcomes following liver resection is less well-defined. This systematic review in accordance with Preferred Reporting It...
journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章,评审
doi:10.1002/jhbp.727
更新日期:2020-07-01 00:00:00
abstract:BACKGROUND:The rate of preoperative biliary drainage for pancreaticoduodenectomy has been increasing despite most recent evidence that favors avoiding it. Only a few studies have focused on late surgical complications - biliary stricture after pancreaticoduodenectomy and have produced only inconclusive results. We eval...
journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章
doi:10.1002/jhbp.559
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND:Whether systemically transplanted human adipose-derived stem cells (ADSCs) homed to the injured liver in nude mice under stress with subsequent hepatectomy (Hx) and ischemia-reperfusion (I/R) was investigated in the present study. The types of cells in the liver that were involved in the homing of ADSCs were...
journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章
doi:10.1002/jhbp.147
更新日期:2014-12-01 00:00:00
abstract::Liver transplantation (LT) has been regarded as "potentially curative" in a cirrhotic patient with hepatocellular carcinoma (HCC) because it removes the cancer and eradicates the cirrhosis. In Taiwan, HCC ranks first among the leading causes of cancer mortality in males and 4th in females. The most common causes are c...
journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章,评审
doi:10.1007/s00534-009-0166-7
更新日期:2010-09-01 00:00:00
abstract:BACKGROUND:Adequate needle size and tissue acquisition techniques for endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) need further elucidation. Moreover, the actual negative pressure and suction forces of FNA needles remain unknown. We evaluated the suction forces of 19-gauge, 22-gauge, and 25-gauge conve...
journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章
doi:10.1002/jhbp.201
更新日期:2015-05-01 00:00:00
abstract:BACKGROUND/PURPOSE:Recent introduction of multi-detector CT (MDCT) and high-speed magnetic resonance (MR) imaging have dramatically advanced visualization and imaging technology in diagnostic and therapeutic strategy in hepatobiliary pancreatic disease. However, image diagnostics have progressed with a background of th...
journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章,评审
doi:10.1007/s00534-009-0192-5
更新日期:2010-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The present study retrospectively analyzed the clinical impact of endoscopic papillectomy on the selection of a treatment strategy for patients with benign-malignant borderline lesions of the major duodenal papilla. PATIENTS AND METHODS:Between November 1995 and July 2009, 28 patients were selec...
journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章
doi:10.1007/s00534-010-0327-8
更新日期:2011-03-01 00:00:00
abstract:BACKGROUND/PURPOSE:The purpose of the present study was to assess long-term outcomes following liver resection for colorectal liver metastases (CRLM) with concurrent extrahepatic disease and to identify the preoperative prognostic factors for selection of operative candidates. METHODS:In this retrospective, multi-inst...
journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章
doi:10.1002/jhbp.810
更新日期:2020-11-01 00:00:00
abstract::Borderline resectable (BR) pancreatic cancer involves the portal vein and/or superior mesenteric vein (PV/SMV), major arteries including the superior mesenteric artery (SMA) or common hepatic artery (CHA), and sometimes includes the involvement of the celiac axis. We herein describe tips and tricks for a surgical tech...
journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章
doi:10.1002/jhbp.184
更新日期:2015-02-01 00:00:00
abstract::Heterogeneity is one of the essential hallmarks of malignancies. Within bulk cancer cells, a striking variability differs in biological characteristics including the proliferation rate, cell-cell interaction, metastatic tendency and even sensitivity to anticancer therapies. Such diversity makes the investigation and t...
journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章,评审
doi:10.1002/jhbp.248
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:Our previous randomized controlled trial revealed no difference in 2-year overall survival (OS) between extended and standard resection for pancreatic adenocarcinoma. The present study evaluated the 5-year OS and recurrence patterns according to the extent of pancreatectomy. METHODS:Between 2006 and 2009, 1...
journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1002/jhbp.465
更新日期:2017-07-01 00:00:00
abstract:AIM:The aim of this study was to evaluate the outcomes following upfront pancreaticoduodenectomy (PD) in severely jaundiced (serum bilirubin level ≥15 mg/dl) patients with malignant distal common bile duct (CBD) obstruction. BACKGROUND:Recent studies have failed to show the benefits of preoperative biliary drainage (P...
journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章
doi:10.1002/jhbp.671
更新日期:2019-11-01 00:00:00
abstract::In the EASL and AASLD guidelines, hepatic resection (HR) is considered the first option for patients in stage 0 (very early HCC). This statement was not based on randomized controlled trials (RCTs) versus other therapies, but on the oncological assumption that HR is the better procedure for obtaining complete tumor ab...
journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 杂志文章,评审
doi:10.1007/s00534-009-0244-x
更新日期:2010-07-01 00:00:00
abstract::Advances in the field of minimally invasive surgery have grown since the original advent of conventional multiport laparoscopic surgery. The recent development of single incision laparoscopic surgery remains a relatively novel technique, and has had mixed reviews as to whether it has been associated with lower pain sc...
journal_title:Journal of hepato-biliary-pancreatic sciences
pub_type: 历史文章,杂志文章,评审
doi:10.1002/jhbp.37
更新日期:2014-01-01 00:00:00