Random-walk mechanism in the genetic recombination.

Abstract:

:We have explained some experimental data of the homologous recombination and the genetic interference in terms of one-dimensional random walk over discrete sites. We first review our previous results. Next, we modify our random-walk model for the homologous recombination into a continuous-site model, and discuss a possible explanation for the previous experimental data obtained by means of the plasmid having one-side homology. Finally, we show that a reaction between an intermediate and a product is indispensable in explaining the genetic interference in terms of our reaction-diffusion model.

journal_name

Adv Exp Med Biol

authors

Fujitani Y,Kawai J,Kobayashi I

doi

10.1007/978-1-4419-5913-3_31

subject

Has Abstract

pub_date

2010-01-01 00:00:00

pages

275-82

eissn

0065-2598

issn

2214-8019

journal_volume

680

pub_type

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