Alpha-1-antitrypsin, CRP and interleukin-6 in ANCA-positive vasculitis.

Abstract:

:Alfa-1-antitrypsin (a-1-AT), C-reactive protein (CRP) and interleukin-6 (IL-6) serum levels were measured during different phases of anti-neutrophil cytoplasmic antibody (ANCA)-positive vasculitis. Correlation between ANCA and these variables was observed. Both a-1-AT and CRP fluctuations indicated changes in activity that could not always be detected by ANCA. On the other hand, these acute phase proteins were also less specific. IL-6 was not as sensitive as CRP and a-1-AT, a clearly increased mean value was observed only in patients with high ANCA titers.

journal_name

Adv Exp Med Biol

authors

Grönhagen-Riska C,Teppo AM,Honkanen E,Ikäheimo R

doi

10.1007/978-1-4757-9182-2_55

subject

Has Abstract

pub_date

1993-01-01 00:00:00

pages

337-40

eissn

0065-2598

issn

2214-8019

journal_volume

336

pub_type

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