Abstract:
:Social interactions have long-term physiological, psychological, and behavioral consequences. Social isolation is a well-recognized but little understood risk factor and prognostic marker of disease; it can have profoundly detrimental effects on both mental and physical well-being, particularly during states of compromised health. In contrast, the health benefits associated with social support (both reduced risk and improved recovery) are evident in a variety of illnesses and injury states; however, the mechanisms by which social interactions influence disease pathogenesis remain largely unidentified. The substantial health impact of the psychosocial environment can occur independently of traditional disease risk factors and is not accounted for solely by peer-encouraged development of health behaviors. Instead, social interactions are capable of altering shared pathophysiological mechanisms of multiple disease states in distinct measurable ways. Converging evidence from animal models of injury and disease recapitulates the physiological benefits of affiliative social interactions and establishes several endogenous mechanisms (inflammatory signals, glucocorticoids, and oxytocin) by which social interactions influence health outcomes. Taken together, both clinical and animal research are undoubtedly necessary to develop a complete mechanistic understanding of social influences on health.
journal_name
Psychosom Medjournal_title
Psychosomatic medicineauthors
Karelina K,DeVries ACdoi
10.1097/PSY.0b013e3182002116subject
Has Abstractpub_date
2011-01-01 00:00:00pages
67-74issue
1eissn
0033-3174issn
1534-7796pii
PSY.0b013e3182002116journal_volume
73pub_type
杂志文章,评审abstract:OBJECTIVE:The objective of this study was to assess the effects of participation in a mindfulness meditation-based stress reduction program on mood disturbance and symptoms of stress in cancer outpatients. METHODS:A randomized, wait-list controlled design was used. A convenience sample of eligible cancer patients enro...
journal_title:Psychosomatic medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00006842-200009000-00004
更新日期:2000-09-01 00:00:00
abstract:OBJECTIVES:Lesbian, gay, and bisexual (LGB) individuals-particularly those who have not disclosed their sexual orientation-are believed to experience increased chronic stress in comparison with heterosexuals. This interdisciplinary study assessed whether psychiatric symptoms (self-rated anxiety, depression, and burnout...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e3182826881
更新日期:2013-02-01 00:00:00
abstract::Previous studies have identified the MMPI-based Cook and Medley hostility scale (Ho) as a predictor of health outcomes. To achieve a better understanding of the construct measured by this scale, Ho items were classified on an a priori basis. Six subsets were identified: Cynicism, Hostile Attributions, Hostile Affect, ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-198901000-00005
更新日期:1989-01-01 00:00:00
abstract::Twenty young male coffee-drinkers consumed 150 mg of caffeine in decaffeinated coffee three times a day for 8 days. On days 3, 4, 7, and 8, caffeine or a placebo was administered in the laboratory at 11 A.M., 8 A.M., 11 A.M., and 8 A.M., respectively, in a randomized double-blind crossover design. There was a blood pr...
journal_title:Psychosomatic medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00006842-199005000-00007
更新日期:1990-05-01 00:00:00
abstract::To study serotonergic involvement in the development of gastric lesions following activity wheel stress, three groups of rats (gastric lesions, no gastric lesions, and home--cage controls) were killed following exposure to the experimental procedures. The brains were dissected into eight specific areas and subjected t...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-198305000-00004
更新日期:1983-05-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to examine the association between psychobiological stress reactivity during healthy pregnancy and depressive symptoms in the early puerperium. METHODS:A sample of healthy nulliparous pregnant women (N = 57) between the ages of 21 and 35 years underwent a standardized psychosoci...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/01.psy.0000244385.93141.3b
更新日期:2006-11-01 00:00:00
abstract:OBJECTIVE:A previous study found a strong association between alexithymia and functional gastrointestinal disorders (FGID). The objective of this study was to investigate whether alexithymia might be a predictor of treatment outcome in patients with FGID. METHODS:A group of FGID outpatients classified by the 'Rome I' ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/01.psy.0000089064.13681.3b
更新日期:2003-09-01 00:00:00
abstract:OBJECTIVE:This study addressed the issue of whether frequent exposure to life events is associated with aggravation or blunting of cardiovascular reactions to acute mental stress. METHODS:In a substantial cohort of 585 healthy young adults, systolic and diastolic blood pressure and pulse rate were recorded at rest and...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/01.psy.0000160464.63264.5d
更新日期:2005-05-01 00:00:00
abstract::In this article, we review the differences between momentary, retrospective, and trait self-report techniques and discuss the unique role that ambulatory reports of momentary experience play in psychosomatic medicine. After a brief historical review of self-report techniques, we discuss the latest perspective that lin...
journal_title:Psychosomatic medicine
pub_type: 杂志文章,评审
doi:10.1097/PSY.0b013e3182546f18
更新日期:2012-05-01 00:00:00
abstract:OBJECTIVE:Psychological factors such as depression affect recovery after whiplash-associated disorders. This study examined the prevalence of pain-related emotions, such as frustration, anger, and anxiety, and their predictive value for postcrash pain recovery during a 1-year follow-up. METHODS:A population-based pros...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e31822f991a
更新日期:2011-10-01 00:00:00
abstract:OBJECTIVE:The Enhancing Recovery in Coronary Heart Disease study was a multicenter clinical trial in which patients with depression and/or low perceived social support after an acute myocardial infarction were randomly assigned to an intervention consisting of cognitive behavior therapy and, in some cases, sertraline, ...
journal_title:Psychosomatic medicine
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1097/01.psy.0000133362.75075.a6
更新日期:2004-07-01 00:00:00
abstract:OBJECTIVE:Accurate perception of asthma episodes increases the likelihood that they will be managed effectively. The purpose of the study was to examine the effect of feedback in a signal detection task on perception of increased airflow obstruction in children with persistent asthma. METHODS:The effect of feedback tr...
journal_title:Psychosomatic medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/PSY.0b013e3182a8bcde
更新日期:2013-10-01 00:00:00
abstract:OBJECTIVE:Although interleukin (IL)-6 plays a significant role in cardiovascular disease, little is known about its relation to psychological risk factors, such as hostility and severity of depressive symptoms. The current study examined the joint effects of severity of depressive symptoms and hostility on plasma IL-6 ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/01.psy.0000062530.94551.ea
更新日期:2003-07-01 00:00:00
abstract::An attempt was made to relate personality to premenstrual tension (PMT), using two groups of 40 parous and 40 mulliparous women, respectively composed of 20 single and 20 married subjects with an age range of 21 to 30 years. The menstrual instruction group had identical age range and means with the nonmenstrual group....
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-198003000-00002
更新日期:1980-03-01 00:00:00
abstract:OBJECTIVE:There is evidence that placebo effects may influence hormone secretion. However, few studies have examined placebo effects in the endocrine system, including oxytocin placebo effects. We studied whether it is possible to trigger oxytocin placebo effects using a classical conditioning paradigm. METHODS:Ninety...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000759
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVE:Research on eating relies on various indices (e.g., stable, momentary, neural) to accurately reflect food-related reactivity (e.g., disinhibition) and regulation (e.g., restraint) outside the laboratory. The degree to which they differentially predict real-world consumption remains unclear. Further, the predi...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000187
更新日期:2015-06-01 00:00:00
abstract:OBJECTIVE:This study aimed to investigate the relationship between waist circumference as a measure of abdominal obesity and brain responses to stress among patients with coronary artery disease (CAD). METHODS:Patients with CAD (N = 151) underwent acute mental stress tasks in conjunction with high-resolution positron ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000776
更新日期:2020-04-01 00:00:00
abstract::Factor analysis of responses from 1002 men and women were used to define two subscales of the Cook and Medley Hostility Scale. Both the Cynicism and the Paranoid Alienation subscale described attitudes of mistrust and alienation, and both were correlated with MMPI factors measuring aspects of psychopathology. It was s...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-198603000-00014
更新日期:1986-03-01 00:00:00
abstract::Three studies on the relationship between life stresses and premature labor were conducted. The first was a retrospective comparison of life events between a group of women who had had premature labor and a group of controls. It was carried out between 3 and 6 months after the premature delivery to neutralize possible...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-198605000-00006
更新日期:1986-05-01 00:00:00
abstract:OBJECTIVE:Stress or emotional traumas are considered risk factors for unexplained fatiguing illnesses. From July to December 2001, the Centers for Disease Control and Prevention conducted a multigeographical pilot study to test the feasibility of a survey to estimate the prevalence of fatiguing illnesses in the United ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/01.psy.0000138116.12495.a2
更新日期:2004-09-01 00:00:00
abstract:OBJECTIVE:Depression has been associated with increased risk of heart failure (HF). Because anxiety is highly comorbid with depression, we sought to establish if anxiety, depression, or their co-occurrence is associated with incident HF. METHODS:A retrospective cohort (N = 236,079) including Veteran's Administration p...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000027
更新日期:2014-02-01 00:00:00
abstract::The personality patterns of cancer patients as found in retrospective case-control studies are often suspected to be consequences of the disease. In this study an attempt was made to remove the bias arising from the disease itself by taking into account two indicator variables for the subject's anticipation of the sub...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-198705000-00009
更新日期:1987-05-01 00:00:00
abstract:OBJECTIVE:This investigation explored the relationship of coping responses and parental history of hypertension to task-induced blood pressure changes. MATERIALS AND METHODS:The sample consisted of 215 black college student volunteers (median age = 25.95 y). During the speaking task, participants responded to standard...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/01.psy.0000097331.10458.f1
更新日期:2003-11-01 00:00:00
abstract::Sixteen healthy women (20-32 years) not taking oral contraceptives were tested at three phases of their menstrual cycles (menses, preovulatory phase, and midluteal phase). Another 16 women taking oral contraceptives served as age-matched controls, and were tested during menses and during phases corresponding to the pr...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-199409000-00005
更新日期:1994-09-01 00:00:00
abstract:OBJECTIVES:Studies have shown that people with cognitive impairment have poor dental health. However, the direction of causality remains unknown. This prospective cohort study aimed to determine the association between four self-reported dental health variables and dementia onset in older Japanese people. METHODS:Anal...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e318246dffb
更新日期:2012-04-01 00:00:00
abstract::MMPI measures of neuroticism (N) and of cynicism (C) were obtained at the initial examination of 1871 employed, middle-aged men in Chicago. Neither N nor C was significantly associated cross-sectionally with systolic blood pressure or serum cholesterol, but both were positively associated with cigarette smoking and al...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-199103000-00006
更新日期:1991-03-01 00:00:00
abstract:OBJECTIVE:Depression has been reported to increase cardiac event rates and functional impairment in patients with coronary disease. This article describes the impact of depression on subsequent healthcare utilization for such patients. METHODS:One hundred ninety-eight health maintenance organization patients with stab...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/01.psy.0000058370.50240.aa
更新日期:2003-03-01 00:00:00
abstract:OBJECTIVE:Reexamine the claim that elderly Chinese-American women are able to prolong their lives until after the celebration of the Harvest Moon Festival. METHODS:See if independent 1985 to 2000 data for Chinese-, Korean-, and Vietnamese-Americans replicate results that were reported using 1960 to 1984 data for Chine...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/01.psy.0000127875.38685.ba
更新日期:2004-05-01 00:00:00
abstract:OBJECTIVE:In this article, we evaluated the prospective association between measures of trait anger, hostility, and anxiety and indices of carotid atherosclerosis in 200 healthy middle-aged postmenopausal women. METHODS:Starting in 1983, 541 premenopausal women were evaluated for their levels of standard cardiovascula...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-199809000-00021
更新日期:1998-09-01 00:00:00
abstract::This study compared the neurobehavioral performance of hypertensive and normotensive men and women using neuropsychological, information-processing, and psychometric assessments. One hundred subjects, including 68 hypertensive and 32 normotensive individuals, completed a test battery that yielded scores on measures of...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-199301000-00008
更新日期:1993-01-01 00:00:00