Abstract:
OBJECTIVE:This study addressed the issue of whether frequent exposure to life events is associated with aggravation or blunting of cardiovascular reactions to acute mental stress. METHODS:In a substantial cohort of 585 healthy young adults, systolic and diastolic blood pressure and pulse rate were recorded at rest and in response to a mental arithmetic stress task. Participants indicated, from a list of 50 events, those they had experienced in the last year. RESULTS:There was an overall association between life events and blunted cardiovascular reactivity that was driven by variations in the frequency of exposure to desirable events. The total number of events and the number of personal events were negatively associated with systolic blood pressure and pulse rate reactions to acute stress, whereas the number of work-related events was negatively associated with diastolic blood pressure and pulse rate reactivity. The negative association between total events and systolic blood pressure reactivity was stronger for women than men, whereas men exposed to frequent undesirable events showed enhanced diastolic blood pressure reactivity. The blunting of pulse rate reactivity associated with frequent personal life events was evident particularly for those who had a relatively large number of close friends. CONCLUSION:The nature and extent of the association between life events exposure and stress reactivity in young adults depends on the valence of the events together with the sex of the individual and their social network size.
journal_name
Psychosom Medjournal_title
Psychosomatic medicineauthors
Phillips AC,Carroll D,Ring C,Sweeting H,West Pdoi
10.1097/01.psy.0000160464.63264.5dsubject
Has Abstractpub_date
2005-05-01 00:00:00pages
384-92issue
3eissn
0033-3174issn
1534-7796pii
67/3/384journal_volume
67pub_type
杂志文章abstract:OBJECTIVE:To test whether depressive symptoms are related to inflammatory and hemostatic markers in women approaching menopause. METHODS:A total of 3292 women enrolled in the Study of Women's Health Across the Nation (SWAN) were followed for five years and had measures of Center for Epidemiologic Studies-Depression an...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/01.psy.0000256574.30389.1b
更新日期:2007-02-01 00:00:00
abstract:OBJECTIVE:Persons with elevated blood pressure (BP) show dampened emotional responses to affect-laden stimuli. We sought to further examine cardiovascular-emotional dampening by examination of the relationship between resting hemodynamic measures and recognition of emotion in an African American community-based sample....
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e318235ed55
更新日期:2011-11-01 00:00:00
abstract:OBJECTIVE:Several somatic illnesses are associated with psychiatric comorbidity. Evidence is provided that availability of the essential amino acid tryptophan, which is the precursor of serotonin, may cause this phenomenon. METHODS:We performed a database search to find relevant articles published between 1966 and 200...
journal_title:Psychosomatic medicine
pub_type: 杂志文章,评审
doi:10.1097/01.psy.0000078188.74020.cc
更新日期:2003-07-01 00:00:00
abstract:OBJECTIVE:We examined whether high waist-to-hip ratio (WHR) in women is a biomarker for increased testosterone (T) and higher levels of sexual desire. METHODS:Participants were 99 healthy nonobese premenopausal women. Trait levels of mean bioavailable T were estimated from three saliva samples collected at 8:00 am, 9:...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/01.psy.0000151747.22904.d7
更新日期:2005-03-01 00:00:00
abstract:OBJECTIVE:Medically unexplained symptoms (MUS), which are highly prevalent in all fields of medicine, are considered difficult to treat. The primary objective of this systematic review and meta-analysis was to assess the efficacy of self-help for adults with MUS. METHODS:Four electronic databases were searched for rel...
journal_title:Psychosomatic medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/PSY.0000000000000325
更新日期:2016-07-01 00:00:00
abstract:OBJECTIVE:This study investigated the physiological and somatic changes evoked by daily exposure to the same type of stressor (homotypic) or different aversive stressor stimuli (heterotypic) in adolescent and adult rats, with a focus on cardiovascular function. The long-term effects of stress exposure during adolescenc...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000141
更新日期:2015-02-01 00:00:00
abstract:OBJECTIVE:Despite a well-documented association between stress and depression with cardiac morbidity and mortality, there is no satisfactory explanation for the mechanisms linking affective and cardiac disorders. This study investigated cardiac electrophysiological properties in an animal model of depression. METHODS:...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e318276cb0d
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVE:Placebo effects relieve various somatic symptoms, but it is unclear how they can be enhanced to maximize positive treatment outcomes. Oxytocin administration may potentially enhance placebo effects, but few studies have been performed, and they have had conflicting findings. The study aim was to investigate t...
journal_title:Psychosomatic medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/PSY.0000000000000571
更新日期:2018-05-01 00:00:00
abstract:OBJECTIVE:Suboptimal self-care by individuals with diabetes mellitus (DM) is a significant public health concern. The common-sense model (CSM) proposes that illness representations are associated with coping and health outcomes across various conditions. The present study examined the efficacy of a CSM-based interventi...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000883
更新日期:2021-01-01 00:00:00
abstract::Factor analysis of responses from 1002 men and women were used to define two subscales of the Cook and Medley Hostility Scale. Both the Cynicism and the Paranoid Alienation subscale described attitudes of mistrust and alienation, and both were correlated with MMPI factors measuring aspects of psychopathology. It was s...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-198603000-00014
更新日期:1986-03-01 00:00:00
abstract:OBJECTIVE:The proportion of overweight and obese people has grown rapidly, and obesity has now been widely recognized as an important public health problem. At the same time, stress has increased in working life. The 2 problems could be connected if work stress promotes unhealthy eating habits and sedentary behavior an...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/01.psy.0000170330.08704.62
更新日期:2005-07-01 00:00:00
abstract:OBJECTIVE:To examine the cross-sectional association between hostility and measures of abdominal fat (visceral, subcutaneous) in middle-aged African American and white women. Because fat-patterning characteristics are known to differ by race, we were particularly interested in examining whether these associations were ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e3181ad13a7
更新日期:2009-09-01 00:00:00
abstract:OBJECTIVE:We examine associations between the perception of ongoing psychological demands by ecological momentary assessment (EMA) and 6-year changes in carotid artery atherosclerosis by ultrasonography. METHODS:A total of 270 initially healthy participants collected ambulatory blood pressure (ABP) and recorded their ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e3182572599
更新日期:2012-05-01 00:00:00
abstract:OBJECTIVE:To review published literature for the highest level of evidence on the efficacy of treatment for patients with medically unexplained symptoms. METHODS:A comprehensive literature search was carried out in Cochrane library, Medline (1971-2007), PsychINFO (1974-2006), and EMBASE (1980-2007) to identify pharmac...
journal_title:Psychosomatic medicine
pub_type: 杂志文章,评审
doi:10.1097/PSY.0b013e31815b5cf6
更新日期:2007-12-01 00:00:00
abstract:OBJECTIVE:Posttraumatic stress disorder (PTSD) is associated with indicators of poor physical health and sleep disturbance. This study investigated the relationship between PTSD and metabolic risk factors and examined the role of sleep duration in medically healthy and medication-free adults. METHODS:Participants with...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000176
更新日期:2015-05-01 00:00:00
abstract:OBJECTIVE:To examine retinal vascular caliber, an indicator of early microvascular disease and depression in patients with Type 2 diabetes. METHODS:We conducted a clinic-based study, comparing participants with Type 2 diabetes with major depression (n = 43), without depression (n = 49), and healthy controls without di...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e3181da90f4
更新日期:2010-07-01 00:00:00
abstract:OBJECTIVE:To assess the relationship among Type D personality, self-efficacy, and medication adherence in patients with coronary heart disease. METHODS:The study design was prospective and observational. Type D personality, self-efficacy for illness management behaviors, and medication adherence were measured 3 weeks ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e31823a5b2f
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVES:Research suggests that individuals with posttraumatic stress disorder (PTSD) are more likely to develop medical conditions and other stress-related psychiatric disorders. Given these findings and others suggesting that PTSD victims may have altered neuroendocrine and immune systems, the hypothesis that Vietn...
journal_title:Psychosomatic medicine
pub_type: 临床试验,杂志文章
doi:10.1097/00006842-199905000-00019
更新日期:1999-05-01 00:00:00
abstract:OBJECTIVES:Exposure is regarded to be a crucial component of therapies for phobias. According to emotional processing theory, the success of exposure therapy is predicted by activation of subjective and physiological fear responses and their within-session habituation and between-session adaptation. This study tested t...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000209
更新日期:2015-09-01 00:00:00
abstract:OBJECTIVE:The present investigation was designed to provide the first empirical examination of the effects of clonidine, a selective alpha 2-adrenergic agonist, on sexual arousal in women with and without prior sympathetic nervous system [SNS] stimulation by exercise. The purpose was to help elucidate the influence of ...
journal_title:Psychosomatic medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00006842-199707000-00010
更新日期:1997-07-01 00:00:00
abstract:OBJECTIVE:This study assessed the relation of stressful life events with survival after breast cancer. METHODS:This study was based on women with histologically confirmed, newly diagnosed, localized or regional stage breast cancer first treated in 1 of 11 Quebec City (Canada) hospitals from 1982 through 1984. Among 76...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-200103000-00017
更新日期:2001-03-01 00:00:00
abstract::Previous work from our group has examined the relationship between stress and immunodepression in medical students taking National Boards, Part I, and has described a relationship between stress intrusion scores (SIS) and immunodepression. We have also shown that a high proportion of individuals with generalized anxie...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-199603000-00007
更新日期:1996-03-01 00:00:00
abstract:OBJECTIVE:The study investigated the effects of moderate doses of caffeine on ambulatory blood pressure and heart rate during workday activities. METHODS:Healthy, nonsmoking, habitual coffee drinkers (N = 21) received daily doses of 100 mg and 500 mg of caffeine on 2 days in a crossover design. Treatment order was ran...
journal_title:Psychosomatic medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00006842-199805000-00019
更新日期:1998-05-01 00:00:00
abstract:OBJECTIVES:African Americans are characterized by higher heart rate variability (HRV), a finding ostensibly associated with beneficial health outcomes. However, these findings are at odds with other evidence that blacks have worse cardiovascular outcomes. Here, we examine associations in a large cohort from the ELSA-Br...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000359
更新日期:2016-10-01 00:00:00
abstract:OBJECTIVE:Despite its simplicity, single-item measures of self-rated health have been associated with mortality independent of objective health conditions. However, little is known about the mechanisms potentially responsible for such associations. This study tested the association between self-rated heath and inflamma...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000683
更新日期:2019-05-01 00:00:00
abstract:OBJECTIVE:The purpose of this study is to assess the role of psychological stress in the expression of illness among infected subjects and to test the plausibility of local proinflammatory cytokine production as a pathway linking stress to illness. METHODS:After completing a measure of psychological stress, 55 subject...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-199903000-00009
更新日期:1999-03-01 00:00:00
abstract:OBJECTIVE:Research in psychosomatic medicine includes a long history of studying how responses to anger-provoking situations are associated with health. In the context of a marriage, spouses may differ in their anger-coping response style. Where one person may express anger in response to unfair, aggressive interperson...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000653
更新日期:2019-01-01 00:00:00
abstract::Rats with a genetic susceptibility to experimental hypertension were exposed daily for 13 weeks to a conflict situation that resulted in food deprivation and the application of electric shock. Other subjects were either food deprived, shocked, both food deprived and shocked but without conflict, or not experimentally ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-197509000-00004
更新日期:1975-09-01 00:00:00
abstract::Two separate studies assessed the influence on menstrual distress and related inhibition of such variables as predictability of onset, dispositional susceptibility to cultural expectations, and the attentional focus provided by labels. Greater predictability of onset was associated with more positive feedlings about m...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-197908000-00004
更新日期:1979-08-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to determine the relationship of lifestyle factors and neurocognitive functioning in older adults with vascular risk factors and cognitive impairment, no dementia (CIND). METHODS:One hundred sixty adults (M [SD] = 65.4 [6.8] years) with CIND completed neurocognitive assessments of ex...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000474
更新日期:2017-07-01 00:00:00