Peripheral eosinophilia as an indicator of meningitic angiostrongyliasis in exposed individuals.

Abstract:

:The diagnosis of meningitic angiostrongyliasis (MA) is based on clinical criteria. A lumbar puncture is used as a diagnostic tool, but it is an invasive procedure. The blood eosinophil levels are also assessed and used in the diagnosis of this disease. We enrolled 47 patients with serologically proven MA and 131 controls with intestinal parasite infections. An absolute eosinophil count model was found to be the best marker for MA. An eosinophil count of more than 798 cells led to sensitivity, specificity, positive predictive and negative predictive values of 76.6%, 80.2%, 58.1% and 90.5%, respectively. These data support the use of testing for high blood eosinophil levels as a diagnostic tool for MA in individuals that are at risk for this disease.

journal_name

Mem Inst Oswaldo Cruz

authors

Sawanyawisuth K,Sawanyawisuth K,Senthong V,Limpawattana P,Intapan PM,Tiamkao S,Jitpimolmard S,Chotmongkol V,Barrett-Connor E

doi

10.1590/s0074-02762010000700020

subject

Has Abstract

pub_date

2010-11-01 00:00:00

pages

942-4

issue

7

eissn

0074-0276

issn

1678-8060

pii

S0074-02762010000700020

journal_volume

105

pub_type

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