Interference with simian virus 40 DNA replication by adenovirus type 2 during mixed infection of monkey cells.

abstract：:The presence of complement-fixing (CF) antibody reactive with T antigen and with viral C antigen in hamsters bearing adenovirus 12-induced tumors has been confirmed. Antibody activity in serum obtained at a time when the host was bearing large tumors was found to be associated exclusively with 7S immunoglobulins. Two ...

journal_title：Journal of virology

authors： Fugmann RA,Sigel MM

更新日期：1967-08-01 00:00:00

abstract：:We have used immunofluorescence in parallel with transmission and scanning electron microscopy to characterize the unusual cytoplasmic and nucleolar accumulation of Simian virus 40 (SV40) virion protein (C antigen) at restrictive temperatures (39 to 41 C) in monkey cells infected with a temperature-sensitive mutant of...

journal_title：Journal of virology

authors： Widmer C,Robb JA

更新日期：1974-12-01 00:00:00

abstract：:The contributions of the glycoproteins gI (ORF67) and gE (ORF68) to varicella-zoster virus (VZV) replication were investigated in deletion mutants made by using cosmids with VZV DNA derived from the Oka strain. Deletion of both gI and gE prevented virus replication. Complete deletion of gI or deletions of 60% of the N...

journal_title：Journal of virology

authors： Mallory S,Sommer M,Arvin AM

更新日期：1997-11-01 00:00:00

abstract：:A recent publication indicated that overexpression of Axl, a cellular receptor that negatively regulates Toll-like receptor signaling, enhanced the entry of viruses pseudotyped with the glycoprotein of lymphocytic choriomeningitis virus (LCMV) in vitro. In testing the biological relevance of these observations, we fou...

journal_title：Journal of virology

authors： Sullivan BM,Welch MJ,Lemke G,Oldstone MB

更新日期：2013-04-01 00:00:00

abstract：:We characterized the cellular immune response to severe acute respiratory syndrome coronavirus (SARS-CoV) infection in 12- to 14-month-old BALB/c mice, a model that mimics features of the human disease. Following intranasal administration, the virus replicated in the lungs, with peak titers on day 2 postinfection. Enh...

journal_title：Journal of virology

authors： Chen J,Lau YF,Lamirande EW,Paddock CD,Bartlett JH,Zaki SR,Subbarao K

更新日期：2010-02-01 00:00:00

abstract：:CTCF and the cohesin complex modify chromatin by binding to DNA and interacting with each other and with other cellular proteins. Both proteins regulate transcription by a variety of local effects on transcription and by long-range topological effects. CTCF and cohesin also bind to herpesvirus genomes at specific site...

journal_title：Journal of virology

authors： Li D,Mosbruger T,Verma D,Swaminathan S

更新日期：2020-01-06 00:00:00

abstract：:Coxsackievirus B3 (CB3) firmly attaches to HeLa cells, forming a specific complex between the virus and its receptor on the cell surface. We extracted this virus-receptor complex (VRC) with the detergents sodium deoxycholate and Triton X-100. The VRC was identified by its sedimentation coefficient (140S), which was le...

journal_title：Journal of virology

authors： Mapoles JE,Krah DL,Crowell RL

更新日期：1985-09-01 00:00:00

abstract：:Mice and cattle injected with plasmids encoding bovine herpesvirus 1 (BHV-1) glycoproteins developed gene-specific antibody responses capable of neutralizing BHV-1. The ability of animals to respond serologically to DNA injections was in part dependent on the quantity of DNA injected and was also negatively affected b...

journal_title：Journal of virology

authors： Cox GJ,Zamb TJ,Babiuk LA

更新日期：1993-09-01 00:00:00

abstract：:Newborn mice suckled on dams immunized either orally or parenterally with primate rotavirus SA-11 were protected against diarrhea induced by SA-11 virus challenge. Experimental oral administration of milk from orally immunized dams protected suckling mice against challenge; protective activity was detected both in the...

journal_title：Journal of virology

authors： Offit PA,Clark HF

更新日期：1985-04-01 00:00:00

abstract：:We previously reported that the cellular transcription factor hypoxia-inducible factor 1α (HIF-1α) binds a hypoxia response element (HRE) located within the promoter of Epstein-Barr virus's (EBV's) latent-lytic switch BZLF1 gene, Zp, inducing viral reactivation. In this study, EBV-infected cell lines derived from gast...

journal_title：Journal of virology

authors： Kraus RJ,Cordes BA,Sathiamoorthi S,Patel P,Yuan X,Iempridee T,Yu X,Lee DL,Lambert PF,Mertz JE

更新日期：2020-08-31 00:00:00

abstract：:The capsid mRNA transcripts of human bocavirus 1 (HBoV1) can be generated by alternative splicing from the mRNA precursor transcribed from the P5 promoter. However, the alternative translation regulation mechanism of capsid mRNA transcripts is largely unknown. Here we report that the polycistronic capsid mRNA transcri...

journal_title：Journal of virology

authors： Liu X,Hao S,Chen Z,Xu H,Wang H,Huang M,Guan W

更新日期：2018-10-12 00:00:00

abstract：:The effect of herpes simplex virus type 2 (HSV-2) infection on the synthesis of DNA in human embryonic fibroblast cells was determined at temperatures permissive (37 C) and nonpermissive (42 C) for virus multiplication. During incubation of HSV-2 infected cultures at 42 C for 2 to 4 days or after shift-down from 42 to...

journal_title：Journal of virology

authors： Melvin P,Kucera LS

更新日期：1975-03-01 00:00:00

abstract：:In this study, we document that efficient interaction between arenavirus nucleoprotein (NP) and RNA-dependent RNA polymerase (L protein), the two trans-acting viral factors required for both virus RNA replication and gene transcription, requires the presence of virus-specific RNA sequences located within the untransla...

journal_title：Journal of virology

authors： Iwasaki M,Ngo N,Cubitt B,de la Torre JC

更新日期：2015-05-01 00:00:00

abstract：:Host cell interactions of human adenovirus serotypes belonging to subgroups B (adenovirus type 3 [Ad3] and Ad7) and C (Ad2 and Ad5) were comparatively analyzed at three levels: (i) binding of virus particles with host cell receptors; (ii) cointernalization of macromolecules with adenovirions; and (iii) adenovirus-indu...

journal_title：Journal of virology

authors： Defer C,Belin MT,Caillet-Boudin ML,Boulanger P

更新日期：1990-08-01 00:00:00

abstract：:Defined segments of the transmembrane envelope glycoprotein (gp45) of equine infectious anemia virus were expressed as TrpLE fusion proteins and examined for their reactivity in Western immunoblots against a diverse panel of equine immune sera. The most immunogenic region of gp45 was localized to its amino terminus, p...

journal_title：Journal of virology

authors： Chong YH,Ball JM,Issel CJ,Montelaro RC,Rushlow KE

更新日期：1991-02-01 00:00:00

abstract：:We investigated the primary cellular immune responses to human immunodeficiency virus type 1 (HIV-1) Env and Gag proteins elicited by recombinant vesicular stomatitis viruses (rVSVs). The primary response to Env peaked 5 to 7 days after intraperitoneal vaccination, at which time 40% of CD8(+) cells were Env tetramer p...

journal_title：Journal of virology

authors： Haglund K,Leiner I,Kerksiek K,Buonocore L,Pamer E,Rose JK

更新日期：2002-03-01 00:00:00

abstract：:Vaccinia virus genes are expressed in a sequential fashion, suggesting a role for negative as well as positive regulatory mechanisms. A potential down regulator of gene expression was mapped by transfection assays to vaccinia virus open reading frame D10, which encodes a protein with no previously known function. Inhi...

journal_title：Journal of virology

authors： Shors T,Keck JG,Moss B

更新日期：1999-01-01 00:00:00

abstract：:We have measured growth of West Nile virus in mouse primary peritoneal macrophages (resident, thioglycolate elicited, and Mycobacterium bovis BCG activated) and in macrophagelike (P338D1) and nonmacrophage (L929, PS clone D) cell lines infected in the absence or presence of specific antibodies (immunoglobulin G ([IgG]...

journal_title：Journal of virology

authors： Cardosa MJ,Gordon S,Hirsch S,Springer TA,Porterfield JS

更新日期：1986-03-01 00:00:00

abstract：:As an approach to identifying hepatocyte receptors for the avian hepadnavirus duck hepatitis B virus (DHBV), hybridomas were prepared from mice immunized with permissive duck hepatocytes. Monoclonal antibodies (MAbs) were screened for the ability to inhibit binding of DHBV particles to primary duck hepatocytes and to ...

journal_title：Journal of virology

authors： Guo JT,Pugh JC

更新日期：1997-06-01 00:00:00

abstract：:Severe complications of Zika virus (ZIKV) infection might be caused by inflammation, but how ZIKV induces proinflammatory cytokines is not understood. In this study, we show opposite regulatory effects of the ZIKV NS5 protein on interferon (IFN) signaling. Whereas ZIKV and its NS5 protein were potent suppressors of ty...

journal_title：Journal of virology

authors： Chaudhary V,Yuen KS,Chan JF,Chan CP,Wang PH,Cai JP,Zhang S,Liang M,Kok KH,Chan CP,Yuen KY,Jin DY

更新日期：2017-06-26 00:00:00

abstract：:China is facing a rapid upsurge in cases of human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV) infection due to large numbers of paid blood donors (PBD), injection drug users (IDU), and sexual partners of infected individuals. In this report, a total of 236 HIV-1-positive blood samples were collec...

journal_title：Journal of virology

authors： Zhang L,Chen Z,Cao Y,Yu J,Li G,Yu W,Yin N,Mei S,Li L,Balfe P,He T,Ba L,Zhang F,Lin HH,Yuen MF,Lai CL,Ho DD

更新日期：2004-12-01 00:00:00

abstract：UNLABELLED:Replication-deficient rabies virus (RABV)-based vaccines induce rapid and potent antibody responses via T cell-independent and T cell-dependent mechanisms. To further investigate early events in vaccine-induced antibody responses against RABV infections, we studied the role of macrophages as mediators of RAB...

journal_title：Journal of virology

authors： Lytle AG,Shen S,McGettigan JP

更新日期：2015-03-01 00:00:00

abstract：:Human cytomegalovirus (HCMV) has evolved multiple strategies for suppression of the antiviral response of the infected cell. DNA array technology has revealed that HCMV clearly regulates host gene expression during the course of a productive infection by enhancing, sustaining, or suppressing steady-state levels of cel...

journal_title：Journal of virology

authors： Gealy C,Denson M,Humphreys C,McSharry B,Wilkinson G,Caswell R

更新日期：2005-01-01 00:00:00

abstract：:Alphavirus expression systems based on suicidal virus particles carrying recombinant replicons have proven to be a very efficient way to deliver genes for heterologous protein expression. However, present strategies for production of such particles have biosafety limitations due to the generation, by RNA recombination...

journal_title：Journal of virology

authors： Smerdou C,Liljeström P

更新日期：1999-02-01 00:00:00

abstract：:Human adenovirus 41 (HAdV-41) causes acute gastroenteritis in young children. The main characteristics of HAdV-41 infection are diarrhea and vomiting. Nevertheless, the precise mechanism of HAdV-41-induced diarrhea is unknown, as a suitable small-animal model has not been described. In this study, we used the human mi...

journal_title：Journal of virology

authors： Westerberg S,Hagbom M,Rajan A,Loitto V,Persson BD,Allard A,Nordgren J,Sharma S,Magnusson KE,Arnberg N,Svensson L

更新日期：2018-03-14 00:00:00

abstract：:Marek's disease herpesvirus (MDV)-transformed lymphoblastoid tumor cell lines were characterized for the presence of the surface markers. Monoclonal antibodies were used for CD3 (T-cell receptor [TCR] complex), TCR1, TCR2, and TCR3, CD4, CD8, and Ia antigen by indirect fluorescence staining followed by microscopic exa...

journal_title：Journal of virology

authors： Schat KA,Chen CL,Calnek BW,Char D

更新日期：1991-03-01 00:00:00

abstract：:The M2-2 protein of respiratory syncytial virus (RSV) is involved in regulation of viral RNA transcription and replication. Encoded by the next-to-last gene of RSV, the M2-2 open reading frame (ORF) overlaps with the upstream M2-1 ORF, suggesting that the production of the M2-2 protein might be tightly regulated durin...

journal_title：Journal of virology

authors： Cheng X,Park H,Zhou H,Jin H

更新日期：2005-11-01 00:00:00

abstract：:Purified Friend viruses obtained from chronically infected tissue cultures were studied under the electron microscope in an effort to correlate the fine structure of the particles to their leukemogenic activity under varied experimental conditions, i.e., temperature treatments and exposure to Tween 80, amyl acetate, o...

journal_title：Journal of virology

authors： De Tkaczevski L,De Harven E,Friend C

更新日期：1968-04-01 00:00:00

abstract：:ICP0 is a potent activator of herpes simplex virus type 1 gene expression in transient assays and in productive infection. A role for ICP0 in reactivation from latency in vivo has also been suggested on the basis of the observation that viruses with mutations in both copies of the diploid gene for ICP0 reactivate less...

journal_title：Journal of virology

authors： Cai W,Astor TL,Liptak LM,Cho C,Coen DM,Schaffer PA

更新日期：1993-12-01 00:00:00

abstract：:Herpes simplex virus 1 (HSV-1) capsids leave the nucleus by a process of envelopment and de-envelopment at the nuclear envelope (NE) that is accompanied by structural alterations of the NE. As capsids translocate across the NE, transient primary enveloped virions form in the perinuclear space. Here, we provide evidenc...

journal_title：Journal of virology

authors： Maric M,Shao J,Ryan RJ,Wong CS,Gonzalez-Alegre P,Roller RJ

更新日期：2011-10-01 00:00:00