Prevalence and risk factors of strongyloidiasis in patients with systemic lupus erythematosus in Southern Thailand.

Abstract:

Background:Strongyloidiasis can be fatal in systemic lupus erythematosus (SLE) patients, but few epidemiological studies have investigated the burden of this tropical disease among the SLE population. This study aimed to assess the prevalence and associated factors of strongyloidiasis among SLE patients in Southern Thailand. Methods:A cross-sectional study was conducted on 180 SLE patients attending the Rheumatology Clinic at Songklanagarind Hospital. Stool specimens were collected and examined using the direct smear technique and agar plate culture technique. Serum anti-Strongyloides stercoralis IgG was measured by IgG-ELISA. Results:The overall prevalence of strongyloidiasis by combined parasitologyl and/or serology was 15.6%. The prevalence of strongyloidiasis by parasitological methods was 2.2%. Positive parasitology and/or serology was associated with male sex and a SLE disease duration of less than two years. Conclusion:Strongyloidiasis is highly prevalent among the SLE population. A combination of serological and parasitological methods increases the rate of diagnosis of strongyloidiasis in SLE patients.

journal_name

Lupus

journal_title

Lupus

authors

Juthong S,Geater AF,Dekumyoy P,Hortiwakul T,Siripaitoon B,Aiewruengsurat D,Thongbun N

doi

10.1177/0961203320911091

subject

Has Abstract

pub_date

2020-05-01 00:00:00

pages

539-546

issue

6

eissn

0961-2033

issn

1477-0962

journal_volume

29

pub_type

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