Nervous system lupus mimics limbic encephalitis.

abstract：:Progressive multifocal leukoencephalopathy (PML) is a rare, deadly demyelinating disease of the central nervous system, which is caused by a reactivation of the DNA polyomavirus JC and occurs in immunosuppressed individuals. So far, only 25 cases have been described in patients with SLE and none survived without antiv...

journal_title：Lupus

authors： Nived O,Bengtsson AA,Jönsen A,Sturfelt G

更新日期：2008-11-01 00:00:00

abstract：:A 24 year old female with hereditary spastic paraplegia presented with intermittent headache for one year. She also had lower abdominal pain and vomiting for two months. She was pale, had icterus and mild splenomegaly. On diagnostic evaluation she was found to have hemolytic anemia, thrombocytopenia and bilateral adre...

journal_title：Lupus

authors： Abdulla MC,Alungal J,Hashim S,Ali MM,Musambil M

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to evaluate the correlation and agreement of spot urine protein/creatinine (P/C) ratio with 24 h proteinuria in patients with lupus nephritis (LN) under different scores of activity index (AI). METHODS:In total, 90 pairs of 24 h urine and spot urine samples from 90 patients with bi...

journal_title：Lupus

authors： Zhang Q,Sun L,Jin L

更新日期：2015-08-01 00:00:00

abstract：:Objective The objective of this report is to evaluate the prevalence and clinico-serological correlations of anti-α-enolase antibody (Ab) in patients with systemic lupus erythematosus (SLE). Methods Thirty-two untreated patients with SLE and 20 age- and sex-matched healthy controls were evaluated by rheumatologic exam...

journal_title：Lupus

authors： Li M,Li J,Wang J,Li Y,Yang P

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:The heterogeneous spectrum of systemic lupus erythematosus (SLE) often presents with secondary complications such as cardiovascular disease (CVD), infections and neoplasms. Our study assessed whether the presence of SLE independently increases or reduces the disparities, accounting for the already higher risk...

journal_title：Lupus

authors： Falasinnu T,Chaichian Y,Li J,Chung S,Waitzfelder BE,Fortmann SP,Palaniappan L,Simard JF

更新日期：2019-12-01 00:00:00

abstract：:The contribution of the p53 Arg72Pro polymorphism in the development of systemic lupus erythematosus (SLE) remains controversial. We investigated the frequency of the p53 Arg72Pro genotype in patients with SLE (n = 155) and in controls (n = 150) in Poland. We found a weak contribution of the Arg/Arg genotype to the mo...

journal_title：Lupus

authors： Piotrowski P,Lianeri M,Mostowska M,Wudarski M,Chwalinska-Sadowska H,Jagodzinski PP

更新日期：2008-02-01 00:00:00

abstract：:Autoantibodies to DNA were discovered over 40 years ago following the discovery a few years earlier of the 'LE' cell phenomenon by Hargraves and colleagues in 1948. These investigators noted that, when leucocytes were incubated with serum from lupus patients, changes in the nucleus could be seen together with phagocyt...

journal_title：Lupus

authors： Mageed RA,Zack DJ

更新日期：2002-01-01 00:00:00

abstract：:Lupus anticoagulant-hypoprothrombinemia syndrome (LA-HPS) is a rare acquired disorder caused by prothrombin antibodies. The disease is most common in the pediatric age group (<16 years), and more prevalent in women. There are well-established clinical diseases associated with LA-HPS, most notably systemic lupus erythe...

journal_title：Lupus

authors： Mulliez SM,De Keyser F,Verbist C,Vantilborgh A,Wijns W,Beukinga I,Devreese KM

更新日期：2015-06-01 00:00:00

abstract：:Objective The lupus impact tracker (LIT) is a 10-item patient reported outcome tool to measure the impact of systemic lupus erythematosus or its treatment on patients' daily lives. Herein, we describe the responsiveness of the LIT and LupusQoL to changes in disease activity, using the systemic lupus erythematosus resp...

journal_title：Lupus

authors： Devilliers H,Bonithon-Kopp C,Jolly M

更新日期：2017-04-01 00:00:00

abstract：:This study was conducted to determine kidney transplantation (KTx) outcomes for Greek patients with renal failure caused by lupus nephritis (LN) compared with matched controls, kidney recipients with other causes of end-stage renal disease (ESRD). Twenty-six patients with systemic lupus erythematosus (SLE) subjected t...

journal_title：Lupus

authors： Lionaki S,Kapitsinou PP,Iniotaki A,Kostakis A,Moutsopoulos HM,Boletis JN

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVE:YB current affiliation: Department of Pediatrics, Hadassah-Hebrew University Medical Center, Mount Scopus, Israel YB and MJS contributed equally to the study and should be regarded as joint first authors on this manuscript. Antiphospholipid syndrome (APS) may present with thrombosis and persistently elevated ...

journal_title：Lupus

authors： Berkun Y,Simchen MJ,Strauss T,Menashcu S,Padeh S,Kenet G

更新日期：2014-09-01 00:00:00

abstract：:In prospective studies, increased levels of cardiolipin-biding antibodies and autoantibodies to oxidized low-density lipoprotein (LDL) have been observed in patients with myocardial infarction (MI). These findings suggest that antiphospholipid antibodies may contribute to the development of MI. The 'oxidative-modifica...

journal_title：Lupus

authors： Vaarala O

更新日期：1998-01-01 00:00:00

abstract：:Recent studies have suggested an association between primary antiphospholipid syndrome (PAPS), antiphospholipid antibodies and some major histocompatibility complex (MHC) antigens. We have studied the relationship between MHC class II antigens and PAPS in 19 patients from the south of Spain. Univariant analysis showed...

journal_title：Lupus

authors： Camps MT,Cuadrado MJ,Ocón P,Alonso A,Gutierrez A,Guil M,Grana MI,de Ramón E

更新日期：1995-02-01 00:00:00

abstract：:Novel risk factors for the progression of atherosclerosis such as C-reactive protein (CRP) and adhesion molecules have stimulated much recent interest in the role of inflammation in atherosclerotic disease. There is also evidence emerging that autoimmunity may have a role in the pathogenesis of atherosclerosis. In thi...

journal_title：Lupus

authors： Gordon PA,George J,Khamashta MA,Harats D,Hughes G,Shoenfeld Y

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVE:The objective of this paper is to assess whether pulmonary hypertension (PH) may be detected at one point in time or longitudinally predicted by serum uric acid (sUA) levels in systemic lupus erythematosus (SLE). METHODS:We conducted a post-hoc analysis of a long-term followed cohort of Mexican SLE patients....

journal_title：Lupus

authors： Castillo-Martínez D,Marroquín-Fabián E,Lozada-Navarro AC,Mora-Ramírez M,Juárez M,Sánchez-Muñoz F,Vargas-Barrón J,Sandoval J,Amezcua-Guerra LM

更新日期：2016-01-01 00:00:00

abstract：:With the use of low-dose heparin, fetal survival of aPL pregnancies is 70-80%, but prematurity and intrauterine growth restriction are common. It is likely, but not proven, that dysregulated placental coagulation and resultant vasculopathy are the cause of fetal loss. Details of dysregulated coagulation remain to be d...

journal_title：Lupus

authors： Lockshin MD

更新日期：1998-01-01 00:00:00

abstract：OBJECTIVE:We sought to describe characteristics of children admitted with pericardial effusion (PCE) and systemic lupus erythematosus (SLE) and determine the association between PCE and outcomes of interest. METHODS:We performed a retrospective cohort study of the Pediatric Health Information System (PHIS). Patients w...

journal_title：Lupus

authors： Dalby ST,Tang X,Daily JA,Sukumaran S,Collins RT,Bolin EH

更新日期：2019-03-01 00:00:00

abstract：:Women's treatment preferences for lupus nephritis vary widely even after adjusting for sociodemographic factors and disease severity. Attitude toward risk may partially explain interpatient variability in treatment preference. The objective of this study was to examine the association between 'risk-attitude' and patie...

journal_title：Lupus

authors： Fraenkel L,Bogardus ST Jr,Wittink DR

更新日期：2003-01-01 00:00:00

abstract：:Choroidal involvement in systemic lupus erythematosus (SLE) occurs infrequently. We report a 45-y-old woman with bilateral chorioretinopathy associated with SLE. Diagnosis was performed using indirect ophthalmoscopy, retinal fluorescein angiography (FA) and green indocianin angiography (ICG). In this patient chorioret...

journal_title：Lupus

authors： Paroli MP,Riso D,Pinca M,Pivetti-Pezzi P

更新日期：2001-01-01 00:00:00

abstract：:One hundred and twenty-nine patients with systemic lupus erythematosus were screened for thyroid function tests. Of these, 8.9% had hyperthyroidism and 3.9% Hashimoto's thyroiditis. Euthyroid sick syndrome was present in 47.8% of patients. There was a high prevalence of antimicrosomal and antithyroglobulin antibodies ...

journal_title：Lupus

authors： Boey ML,Fong PH,Lee JS,Ng WY,Thai AC

更新日期：1993-02-01 00:00:00

abstract：:This report considers the rare situation in which primary antiphospholipid syndrome (PAPS) is linked with thrombotic thrombocytopenic purpura (TTP). It describes the case of a young lady with PAPS, characterized by recurring cerebro-vascular abnormalities and marked livedo reticularis, combined with circulating antica...

journal_title：Lupus

authors： de Carvalho JF,Freitas CA,Lima IV,Leite CC,Lage LV

更新日期：2009-08-01 00:00:00

abstract：:Although osteoporosis has traditionally been considered a disease of women, men also incur substantial bone loss with aging, and elderly men have age-specific hip fracture incidence rates and vertebral fracture prevalence rates that are at least half those in women. Early postmenopausal bone loss (which results in the...

journal_title：Lupus

authors： Khosla S,Melton LJ 3rd,Riggs BL

更新日期：1999-01-01 00:00:00

abstract：:Cells traffic in both directions between the fetus and the mother during pregnancy. Recent studies indicate that a low level of fetal cells commonly persists in the maternal circulation for years after pregnancy completion. The harboring of DNA or cells from another individual at low levels is called microchimerism. C...

journal_title：Lupus

authors： Nelson JL

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Pediatric-onset SLE (pSLE) is a multisystem autoimmune disease. Recently, the ficolin-2 (FCN2) gene has emerged as a potential candidate gene for susceptibility to SLE. OBJECTIVES:The objective of this study was to evaluate the association of the FCN2 gene polymorphisms at positions -986 (G/A), -602 (G/A), ...

journal_title：Lupus

authors： Elkoumi MA,Emam AA,Allah MAN,Sherif AH,Abdelaal NM,Mosabah A,Zakaria MT,Soliman MM,Salah A,Sedky YM,Mashali MH,Elashkar SSA,Hafez SFM,Hashem MIA,Elshreif AM,Youssef M,Fahmy DS,Sallam MM,Nawara AM,Elgohary EA,Ahmed

更新日期：2019-07-01 00:00:00

abstract：:Objective Several studies have evaluated the prevalence of rheumatoid factor (RF) and anti-citrullinated proteins antibodies (ACPA) in systemic lupus erythematosus (SLE) patients but no data are available on the anti-carbamylated proteins (anti-CarP), a new biomarker for rheumatoid arthritis (RA). We evaluated the ant...

journal_title：Lupus

authors： Massaro L,Ceccarelli F,Colasanti T,Pendolino M,Perricone C,Cipriano E,Natalucci F,Capalbo G,Lucchetti R,Pecani A,Vomero M,Mancini R,Spinelli FR,Alessandri C,Valesini G,Conti F

更新日期：2018-01-01 00:00:00

abstract：:Nephropathy of antiphospholipid antibody syndrome (NAPS) is an increasingly well-recognized aspect of antiphospholipid syndrome. The most characteristic histopathology is that of thrombotic microangiopathy, and thrombosis occurring in the renal vasculature is thought to be the initiating event. Other less common patho...

journal_title：Lupus

authors： Lin YQ,Lakshminarayanan S,Yamase H,Palmisano J,Parke A

更新日期：2009-05-01 00:00:00

abstract：:Vaccines have undoubtedly brought overwhelming benefits to mankind and are considered safe and effective. Nevertheless, they can occasionally stimulate autoantibody production or even a recently defined syndrome known as autoimmune/inflammatory syndrome induced by adjuvants (ASIA). There is scarce data regarding autoi...

journal_title：Lupus

authors： Perdan-Pirkmajer K,Thallinger GG,Snoj N,Čučnik S,Žigon P,Kveder T,Logar D,Praprotnik S,Tomšič M,Sodin-Semrl S,Ambrožič A

更新日期：2012-02-01 00:00:00

abstract：:The metabolism of poly(ADP-ribose) in peripheral blood mononuclear (PBM) cells was studied in 13 patients with systemic lupus erythematosus (SLE) and in 12 age and sex matched controls. Poly(ADP-ribose) polymerase activity was measured as the net accumulation of ADP-ribose polymers during the conversion of 32P-NAD to ...

journal_title：Lupus

authors： Chen HY,Pertusi RM,Kirkland JB,Rubin BR,Jacobson EL

更新日期：1996-02-01 00:00:00

abstract：OBJECTIVES:To compare and rank currently available pharmacological interventions for the prevention of recurrent miscarriage (RM) in women with antiphospholipid syndrome (APS). METHODS:A search was performed using PubMed, Embase, the Cochrane Central Register of Controlled Trials, Web of Science, CNKI, ClinicalTrials....

journal_title：Lupus

authors： Yang Z,Shen X,Zhou C,Wang M,Liu Y,Zhou L

更新日期：2021-01-01 00:00:00

abstract：:In vitro data showed that immunoglobulin G (IgG) from lupus nephritis (LN) patients could bind to proximal renal tubular epithelial cells (PTEC), but the clinical relevance of such binding remained unclear. Binding of IgG and subclasses to PTEC was measured by cellular ELISA (expressed as OD index) in 189 serial serum...

journal_title：Lupus

authors： Yap DY,Yung S,Zhang Q,Tang C,Chan TM

更新日期：2016-01-01 00:00:00