Abstract:
:Novel risk factors for the progression of atherosclerosis such as C-reactive protein (CRP) and adhesion molecules have stimulated much recent interest in the role of inflammation in atherosclerotic disease. There is also evidence emerging that autoimmunity may have a role in the pathogenesis of atherosclerosis. In this article we explore the evidence for the role of autoimmunity in human atherosclerosis, both in the general population and in the context of the antiphospholipid syndrome. In particular we will focus on several autoantigens, review the evidence for their role in the process of atherosclerosis and the nature of the immune responses.
journal_name
Lupusjournal_title
Lupusauthors
Gordon PA,George J,Khamashta MA,Harats D,Hughes G,Shoenfeld Ydoi
10.1191/096120301680416922subject
Has Abstractpub_date
2001-01-01 00:00:00pages
249-52issue
4eissn
0961-2033issn
1477-0962journal_volume
10pub_type
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