Effects of cadmium in freshwater clams. II. Ultrastructural changes in the renal system ofAnodonta cygnea.

Abstract:

:An ultrastructural study was made of the renal system of freshwater clams,Anodonta cygnea, that had been exposed to cadmium chloride (50 μg Cd/L) for 12 weeks. By stereological analysis an extended lysosomal system and a decreased number of mitochondria was apparent in the epithelial cells lining the proximal compartment of the kidney. The increase of the lysosomal system was mainly accountable to the appearance of a distinct type of lysosome, that accumulated in the apical cell region. The decrease of the mitochondrial population was accompanied by a considerable swelling of the individual mitochondria. Finally, a severe reduction of the glycogen stores was noticed. Similar, but less obvious, changes occurred in the distal kidney compartment. The results suggest that long-term exposure ofAnodonta cygnea to cadmium stimulates the lysosomal system and disturbs the function of organelles involved in the energy metabolism of resorptive kidney cells.

authors

Hemelraad J,Herwig HJ,van Donselaar EG,Holwerda DA,Zandee DI

doi

10.1007/BF01183986

subject

Has Abstract

pub_date

1990-09-01 00:00:00

pages

691-8

issue

5

eissn

0090-4341

issn

1432-0703

journal_volume

19

pub_type

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