Ovarian cancer linked to Lynch syndrome typically presents as early-onset, non-serous epithelial tumors.

abstract：BACKGROUND:Fallopian tube cancer is the rarest of all gynecologic cancers. An extensive literature search on Medline reveals no previous case reports of fallopian tube carcinoma in association with a term pregnancy. CASE:A woman with surgical stage IIB fallopian tube carcinoma was treated with limited staging laparoto...

journal_title：Gynecologic oncology

authors： Adolph A,Le T,Khan K,Biem S

更新日期：2001-04-01 00:00:00

abstract：OBJECTIVE:Preoperative identification of cervical stromal invasion in endometrial carcinoma is important to select patients for primary radical hysterectomy. The objective of this prospective implementation study was to assess if introduction of magnetic resonance imaging (MRI) in addition to the standardly applied end...

journal_title：Gynecologic oncology

authors： Haldorsen IS,Berg A,Werner HM,Magnussen IJ,Helland H,Salvesen OO,Trovik J,Salvesen HB

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVE:To compare the diagnostic accuracy of dilatation & curettage (D&C) vs. endometrial aspiration biopsy in follow-up evaluation of patients treated with high-dose oral progestin plus levonorgestrel intrauterine system (LNG-IUS) for early-stage endometrial cancer (EC). METHOD:A prospective observational study wa...

journal_title：Gynecologic oncology

authors： Kim MK,Seong SJ,Song T,Kim ML,Yoon BS,Jun HS,Lee GH,Lee YH

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:The purpose of this case-controlled study was to determine the prevalence of anemia and incidence of perioperative blood transfusions in patients undergoing treatment for advanced ovarian cancer with neoadjuvant chemotherapy (NACT) or primary debulking surgery (PDS). METHODS:We performed a single institution...

journal_title：Gynecologic oncology

authors： O'Shea A,McCool K,Harrison R,Sampene E,Connor J,Barroilhet L

更新日期：2018-07-01 00:00:00

abstract：:The aim of the present study was to compare the diagnostic accuracy of transvaginal sonography, color flow imaging, and serum CA 125 assay in pre- and postmenopausal women undergoing laparotomy for a clinical diagnosis of an adnexal mass. In 109 consecutive women, the morphology of the mass was evaluated with transvag...

journal_title：Gynecologic oncology

authors： Strigini FA,Gadducci A,Del Bravo B,Ferdeghini M,Genazzani AR

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:It has not been fully clarified whether alteration of Bax and other apoptosis-relating proteins of Bcl-2 and p53 is involved in endometrial carcinogenesis. METHODS:A total of 56 frozen tissues, which included 14 normal endometria, 13 endometrial hyperplasias (10 without atypia and 3 with atypia), and 29 end...

journal_title：Gynecologic oncology

authors： Sakuragi N,Salah-eldin AE,Watari H,Itoh T,Inoue S,Moriuchi T,Fujimoto S

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:Evidence on the incidence and risk factors for lower limb lymphedema (LLL) associated with endometrial cancer is limited. Our objective was to use data from a prospective, longitudinal gynecological cancer cohort study to determine LLL incidence up to 24 months post-diagnosis of endometrial cancer and to exp...

journal_title：Gynecologic oncology

authors： Pigott A,Obermair A,Janda M,Vagenas D,Ward LC,Reul-Hirche H,Hayes SC

更新日期：2020-08-01 00:00:00

abstract：:The role of elective lymphadenectomy in the treatment of patients with early-stage malignancies, although still commonly performed, remains a matter of controversy. This issue is important in the management of cancers and raises questions about the biologic interpretation of their natural history and about motives for...

journal_title：Gynecologic oncology

authors： Santin AD,Parham GP

更新日期：1998-01-01 00:00:00

abstract：OBJECTIVE:Primary debulking surgery (PDS) has historically been the standard treatment for advanced ovarian cancer. Recent data appear to support a paradigm shift toward neoadjuvant chemotherapy with interval debulking surgery (NACT-IDS) for a subset of women with advanced ovarian cancer. It remains unresolved whether ...

journal_title：Gynecologic oncology

authors： Rauh-Hain JA,Nitschmann CC,Worley MJ Jr,Bradford LS,Berkowitz RS,Schorge JO,Campos SM,del Carmen MG,Horowitz NS

更新日期：2013-04-01 00:00:00

abstract：:Thirty-eight patients with advanced or recurrent carcinoma of the endometrium who had received no prior chemotherapy were placed on study by the Gynecologic Oncology Group. One was deemed histologically ineligible. Three patients had insufficient trials to evaluate response. Of the remaining 34 who received hexamethyl...

journal_title：Gynecologic oncology

authors： Thigpen JT,Blessing JA,Ball H,Hanjani P,Manetta A,Homesley H

更新日期：1988-11-01 00:00:00

abstract：:Fourteen patients with malignant nondysgerminomatous germ-cell tumors of the ovary were treated with a combination of high-dose cisplatin, vinblastine, bleomycin, and etoposide (PVeBV regimen). Nine patients received PVeBV as primary postoperative therapy, of whom four had no residual disease. Four patients received P...

journal_title：Gynecologic oncology

authors： Culine S,Kattan J,Lhomme C,Duvillard P,Michel G,Castaigne D,Leclere J,Pico J,Droz JP

更新日期：1994-07-01 00:00:00

abstract：OBJECTIVE:To date, The Cancer Genome Atlas (TCGA) has provided the most extensive molecular characterization of invasive cervical cancer (ICC). Analysis of reverse phase protein array (RPPA) data from TCGA samples showed that cervical cancers could be stratified into 3 clusters exhibiting significant differences in sur...

journal_title：Gynecologic oncology

authors： Rader JS,Pan A,Corbin B,Iden M,Lu Y,Vellano CP,Akbani R,Mills GB,Simpson P

更新日期：2019-11-01 00:00:00

abstract：:This 12-year retrospective study examines the significance of margin involvement with dysplasia at cone biopsy in relation to follow-up. Of 300 cone biopsies, 123 (41%) had margin involvement. These cases of margin involvement were associated with more severe dysplasia (P less than 0.0001) and a higher chance of subse...

journal_title：Gynecologic oncology

authors： Paterson-Brown S,Chappatte OA,Clark SK,Wright A,Maxwell P,Taub NA,Raju KS

更新日期：1992-08-01 00:00:00

abstract：OBJECTIVE:This study was undertaken to evaluate the efficacy of postoperative concurrent chemoradiotherapy (CCRT) and to investigate the recurrence and survival rates after adjuvant CCRT in high-risk early cervical cancer (stages IA2, IB, IIA) patients who were treated by radical hysterectomy and pelvic lymphadenectomy...

journal_title：Gynecologic oncology

authors： Ryu HS,Chun M,Chang KH,Chang HJ,Lee JP

更新日期：2005-02-01 00:00:00

abstract：:A 46-year-old women presented with an inoperable low-grade endometrial stromal sarcoma. Two doses of Depo-Lupron, 7.5 mg, and Megace, 160 mg/day, were given to control uterine bleeding and shrink the tumor mass. In 9 weeks, significant reduction in the tumor occurred allowing for surgical resection. Total abdominal hy...

journal_title：Gynecologic oncology

authors： Scribner DR Jr,Walker JL

更新日期：1998-12-01 00:00:00

abstract：OBJECTIVE:Ovarian carcinomas that originate from fallopian epithelial cells are suggested to arise due to repeated exposure to ovulatory follicular fluid (FF). Mechanistic explanation(s) for how this occurs are unknown. Here, we sought to understand if FF exposure to fallopian epithelial cells could induce DNA damage a...

journal_title：Gynecologic oncology

authors： Brachova P,Alvarez NS,Van Voorhis BJ,Christenson LK

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:The serum CA-125 antigen value has proven to be useful in predicting changes that affect prognosis and management of ovarian cancer; however, interpreting variations in the tumor marker is still not well-defined. Our goal was to further understand the analytical variability of CA-125 in a conventional hospit...

journal_title：Gynecologic oncology

authors： Tso E,Elson P,Vanlente F,Markman M

更新日期：2006-10-01 00:00:00

abstract：:Between 1972 and 1977, 141 patients with benign gynecologic disease and 149 patients with carcinoma of the cervix were evaluated with peritoneal fluid cytology at time of celiotomy. There was no positive cytology (malignant cells) in the benign disease group. The overall incidence of positive peritoneal cytology in th...

journal_title：Gynecologic oncology

authors： Abu-Ghazaleh S,Johnston W,Creasman WT

更新日期：1984-02-01 00:00:00

abstract：:The pelvis is the predominant site of failure following radical radiotherapy (RT) for locally advanced cervical cancer. We report the results of phase I-II studies on 200 patients with bulky (greater than or equal to 5 cm) carcinoma of the cervix. Patients were treated between 1981 and 1988 on sequential protocols of ...

journal_title：Gynecologic oncology

authors： Thomas G,Dembo A,Fyles A,Gadalla T,Beale F,Bean H,Pringle J,Rawlings G,Bush R,Black B

更新日期：1990-09-01 00:00:00

abstract：:Aggressive cytoreductive surgery followed by combination chemotherapy for stage III ovarian carcinoma has resulted in a significant percentage of complete clinical responses. However, 30-50% of patients with no clinical evidence of disease are found to have residual carcinoma at second-look surgical reassessment. Beca...

journal_title：Gynecologic oncology

authors： Hoskins WJ,Lichter AS,Whittington R,Artman LE,Bibro MC,Park RC

更新日期：1985-03-01 00:00:00

abstract：:An improved assay for the measurement of human ovarian tumor antigen NB/70K (triton NB/70K assay) has been developed. This assay makes the accurate and reproducible estimation of serum NB/70K possible. Freezing and thawing of serum up to three times or refrigeration of diluted serum up to 7 days does not significantly...

journal_title：Gynecologic oncology

authors： Knauf S,Taillon-Miller P

更新日期：1984-09-01 00:00:00

abstract：OBJECTIVE:Benefits of laparoscopy over laparotomy in patients with endometrial cancer (EC) are well known. As many patients with EC carry co-morbid conditions, surgery is exposing them to increased risk of complications. A review of the patients with EC recruited so far in a clinical trial comparing laparoscopy to lapa...

journal_title：Gynecologic oncology

authors： Tozzi R,Malur S,Koehler C,Schneider A

更新日期：2005-04-01 00:00:00

abstract：OBJECTIVE:Voiding dysfunctions represent a leading morbidity after radical hysterectomy performed in patients with early-stage cervical cancer. The aim of this study was to perform ad hoc analysis of factors influencing voiding recovery in SENTIX (SENTinel lymph node biopsy in cervIX cancer) trial. METHODS:The SENTIX ...

journal_title：Gynecologic oncology

authors： Zapardiel I,Kocian R,Köhler C,Klat J,Germanova A,Jacob A,Bajsova S,Böhmer G,Lay L,Gil-Ibañez B,Havelka P,Kipp B,Szewczyk G,Toth R,Staringer JC,De Santiago J,Coronado PJ,Poka R,Laky R,Luyckx M,Fastrez M,Dusek L,

更新日期：2021-01-05 00:00:00

abstract：OBJECTIVE:The objective of this study is to determine the incidence of endometrial cancer in young postmenopausal women presenting with vaginal bleeding. METHODS:Cross-sectional study of postmenopausal women presenting with vaginal bleeding in a gynaecological oncology centre in the United Kingdom. All women underwent...

journal_title：Gynecologic oncology

authors： Burbos N,Musonda P,Crocker SG,Morris EP,Duncan TJ,Nieto JJ

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:An epigenetic approach to explaining endometrial carcinogenesis necessitates good understanding of Ras association domain family 1 isoform A (RASSF1A) promoter methylation data from primary studies. AIMS:Differential magnitude of reported associations between RASSF1A promoter methylation and endometrial can...

journal_title：Gynecologic oncology

authors： Pabalan N,Kunjantarachot A,Ruangpratheep C,Jarjanazi H,Christofolini DM,Barbosa CP,Bianco B

更新日期：2017-09-01 00:00:00

abstract：:Twelve patients with recurrent squamous cell carcinoma of the cervix restricted to the pelvis were treated with intra-arterial infusion of carboplatin. The initial carboplatin dose was 300 mg/m2, every 4 weeks, and the dose was escalated to 450 mg/m2. Myelosuppression was the dose-limiting toxicity at the 450 mg/m2 do...

journal_title：Gynecologic oncology

authors： Verma S,Prefontaine M,Bertrand M,Genest P,Dahrouge S

更新日期：1994-06-01 00:00:00

abstract：OBJECTIVES:Few studies have comprehensively tested all ovarian cancer patients for BRCA1 and BRCA2 (BRCA1/2) mutations. We sought to determine if clinically identified mutation carriers differed in clinical characteristics and outcomes from mutation carriers not identified during routine clinical care. METHODS:We incl...

journal_title：Gynecologic oncology

authors： Norquist BM,Pennington KP,Agnew KJ,Harrell MI,Pennil CC,Lee MK,Casadei S,Thornton AM,Garcia RL,Walsh T,Swisher EM

更新日期：2013-03-01 00:00:00

abstract：:Two cases of primary retroperitoneal mucinous cystoadenocarcinoma of the ovarian type are reported. Both tumors occurred in females with bilateral normal ovaries and contained benign, borderline, and malignant mucinous epithelium. Full-thickness infiltration of the cyst wall was not found. In addition to surgery, one ...

journal_title：Gynecologic oncology

authors： Tenti P,Carnevali L,Tateo S,Durola R

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:Five-Year survival after pelvic exenteration for gynecologic malignancies has been reported as high as 60%. The objective of this study was to determine overall survival (OS) after pelvic exenteration and evaluate factors impacting outcome. METHODS:A retrospective review of all women who underwent pelvic ex...

journal_title：Gynecologic oncology

authors： Westin SN,Rallapalli V,Fellman B,Urbauer DL,Pal N,Frumovitz MM,Ramondetta LM,Bodurka DC,Ramirez PT,Soliman PT

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVE:Therapy related acute myeloid leukemia (t-AML) is a potential late complication of cytotoxic therapy, and it is of particular concern in the treatment of patients with epithelial ovarian carcinoma (EOC) exposed to multiple courses of chemotherapy during the course of their disease. This study examines the inc...

journal_title：Gynecologic oncology

authors： Vay A,Kumar S,Seward S,Semaan A,Schiffer CA,Munkarah AR,Morris RT

更新日期：2011-12-01 00:00:00