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Outcome of investigations for postmenopausal vaginal bleeding in women under the age of 50 years.

Abstract：

OBJECTIVE:The objective of this study is to determine the incidence of endometrial cancer in young postmenopausal women presenting with vaginal bleeding. METHODS:Cross-sectional study of postmenopausal women presenting with vaginal bleeding in a gynaecological oncology centre in the United Kingdom. All women underwent transvaginal ultrasound scanning (TVS) as the initial investigation tool to evaluate the endometrium. Endometrial biopsy was performed only in cases where endometrial thickness measured equal to or greater than 5mm. The patients were divided into two groups based on their age: less than 50 years (Group A) and 50 years or older (Group B). RESULTS:Over a 57-month period, 4454 women were investigated for postmenopausal vaginal bleeding. Of these, 259 (5.8%) women were diagnosed with endometrial carcinoma. 260 (5.8%) women were younger than 50 years. Endometrial biopsy was not performed in 130 women in Group A that had an endometrial thickness measurement of less than 5mm on ultrasonography. With a median follow-up period of 3 (1-5) years, we found no cases of endometrial cancer in women under the age of 50 that did not undergo endometrial biopsy at the time of initial evaluation. Overall, no cases of endometrial cancer were diagnosed in postmenopausal women under the age of 50 years. CONCLUSIONS:We found no cases of endometrial cancer amongst 260 women presenting with postmenopausal vaginal bleeding under the age of 50 years. These women could be investigated on a less urgent basis depending on the available resources.

journal_name

Gynecol Oncol

journal_title

Gynecologic oncology

authors

Burbos N,Musonda P,Crocker SG,Morris EP,Duncan TJ,Nieto JJ

doi

10.1016/j.ygyno.2011.12.453

subject

Has Abstract

pub_date

2012-04-01 00:00:00

pages

120-3

issue

1

eissn

0090-8258

issn

1095-6859

pii

S0090-8258(12)00004-2

journal_volume

125

pub_type

杂志文章

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