A phase II study of high-dose cisplatin, vinblastine, bleomycin, and etoposide (PVeBV regimen) in malignant nondysgerminomatous germ-cell tumors of the ovary.

abstract：OBJECTIVE:The aim of this study was to assess whether microvessel density (measured by CD31), vascular endothelial growth factor (VEGF) or multidrug resistance (MDR1) could determine the response to chemotherapy or act as prognostic factors in ovarian cancer. METHODS:Seventy-nine ovarian specimens were immunostained. ...

journal_title：Gynecologic oncology

authors： O'Toole SA,Sheppard BL,Laios A,O'Leary JJ,McGuinness EP,D'Arcy T,Bonnar J

更新日期：2007-02-01 00:00:00

abstract：:Copyright ...

journal_title：Gynecologic oncology

authors： Kodama J,Yoshinouchi M

更新日期：1998-07-01 00:00:00

abstract：:The purpose of this study was to determine the response of vulvar intraepithelial neoplasia (VIN) lesions to standard treatment methods in women infected with human immunodeficiency virus (HIV). We reviewed all cases of VIN over a 4-year period at an inner-city hospital. We reviewed the clinical records of these women...

journal_title：Gynecologic oncology

authors： Korn AP,Abercrombie PD,Foster A

更新日期：1996-06-01 00:00:00

abstract：INTRODUCTION:The benefit of adjuvant chemotherapy for Stage IC grade 1 and stage IA/IB grade 2 endometrioid ovarian adenocarcinoma (EOOC) remains unclear as the NCCN guidelines recommend either observation only or adjuvant chemotherapy. Therefore, we sought to determine whether patients with stage I EOOC had improved o...

journal_title：Gynecologic oncology

authors： Nasioudis D,Latif NA,Simpkins F,Cory L,Giuntoli RL 2nd,Haggerty AF,Morgan MA,Ko EM

更新日期：2020-02-01 00:00:00

abstract：:The relationship between the amount of silver-stained nucleolar organizer regions (AgNORs) and the DNA content of interphase neoplastic cells in 63 cases of human endometrial adenocarcinoma was studied. Interphase AgNOR content was determined as the mean AgNOR area per nucleus by image cytometry in silver-stained samp...

journal_title：Gynecologic oncology

authors： Trerè D,Melchiorri C,Chieco P,Marabini A,Derenzini M

更新日期：1994-05-01 00:00:00

abstract：OBJECTIVE:Oncolytic adenoviruses capable of replication selectively in tumor cells are an appealing approach for the treatment of neoplastic diseases refractory to conventional therapies. The aim of this study was to evaluate the effect of dose and scheduling of a tropism-modified, adenovirus serotype 3 receptor-target...

journal_title：Gynecologic oncology

authors： Raki M,Särkioja M,Desmond RA,Chen DT,Bützow R,Hemminki A,Kanerva A

更新日期：2008-01-01 00:00:00

abstract：:Endocrine and clinicopathologic findings in a 77-year-old woman with ovarian mucinous adenofibroma of borderline malignancy are reported. The preoperative levels of testosterone, androstenedione, estrone, and estradiol in her peripheral blood were 91 ng/ml, 3.78 ng/ml, 82 pg/ml, and 35 pg/ml, respectively, abnormally ...

journal_title：Gynecologic oncology

authors： Tohya T,Mizutani H,Katabuchi H,Miyazaki K,Okamura H

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:Patients who undergo pelvic floor resection as treatment for recurrent cancer following radiation therapy have increased rates of complications, particularly if permanent prosthetic mesh is used for reconstruction. Human acellular dermal matrix (HADM), commonly used for reconstruction in other torso location...

journal_title：Gynecologic oncology

authors： Said HK,Bevers M,Butler CE

更新日期：2007-12-01 00:00:00

abstract：OBJECTIVE:To compare the oncologic outcome of women who underwent fertility-sparing surgery (FSS) vs. radical surgery (RS) for treatment of NEOC in a prospective, nationwide, population-based study and report on the reproductive outcomes in women after FSS. METHODS:Using the Swedish Quality Register for Gynecological ...

journal_title：Gynecologic oncology

authors： Johansen G,Dahm-Kähler P,Staf C,Flöter Rådestad A,Rodriguez-Wallberg KA

更新日期：2019-11-01 00:00:00

abstract：:One of the most prevalent potential therapeutic targets for women with endometrioid endometrial cancer (EC) is the estrogen receptor (ER)/progesterone receptor (PR) pathway. Despite a high proportion of endometrioid ECs being ER and/or PR positive, endocrine therapy is only effective in a minority of women with EC and...

journal_title：Gynecologic oncology

authors： Jerzak KJ,Duska L,MacKay HJ

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVE:To examine tumor characteristics and survival outcome of women with uterine carcinosarcoma who had a history of tamoxifen use. METHODS:This is a multicenter retrospective study examining stage I-IV uterine carcinosarcoma cases based on history of tamoxifen use. Patient demographics, tumor characteristics, tr...

journal_title：Gynecologic oncology

authors： Matsuo K,Ross MS,Bush SH,Yunokawa M,Blake EA,Takano T,Ueda Y,Baba T,Satoh S,Shida M,Ikeda Y,Adachi S,Yokoyama T,Takekuma M,Takeuchi S,Nishimura M,Iwasaki K,Yanai S,Klobocista MM,Johnson MS,Machida H,Hasegawa K,

更新日期：2017-02-01 00:00:00

abstract：:Results of treatment and potential prognostic factors in 54 patients with clinical stage II endometrial carcinoma were analyzed. During the period analyzed, three different treatment techniques were used. The highest cure rate (70.6%) was observed in patients treated with simple hysterectomy and bilateral salpingo-oop...

journal_title：Gynecologic oncology

authors： Andersen ES

更新日期：1990-08-01 00:00:00

abstract：:Iatrogenic immune suppression following renal transplantation is frequently associated with certain neoplasms, including vulvar carcinoma. We describe a patient with a vulvar carcinoma less than 1 mm depth of invasion and less than 3 mm superficial spread 12 years after renal transplantation. A simple vulvectomy was p...

journal_title：Gynecologic oncology

authors： Volgger B,Marth C,Zeimet A,Müller-Holzner E,Ruth N,Dapunt O

更新日期：1997-04-01 00:00:00

abstract：OBJECTIVE:Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a classical glycolytic protein. A higher level of GAPDH mRNA was found in lung, pancreas, and prostate cancers, but in cervical carcinoma there have not been any reports about the level of GAPDH gene expression. So, we tried to investigate the GAPDH gene exp...

journal_title：Gynecologic oncology

authors： Kim JW,Kim SJ,Han SM,Paik SY,Hur SY,Kim YW,Lee JM,Namkoong SE

更新日期：1998-11-01 00:00:00

abstract：OBJECTIVE:To prospectively evaluate the feasibility of detecting human papillomavirus (HPV) type 16, 18 and 52 DNA in the peripheral blood of patients with cervical cancer using real-time polymerase chain reaction (PCR) and to determine its prognostic importance. METHODS:Blood and cervical swab specimens from 135 cons...

journal_title：Gynecologic oncology

authors： Ho CM,Yang SS,Chien TY,Huang SH,Jeng CJ,Chang SF

更新日期：2005-12-01 00:00:00

abstract：:A population-based survey (AFRODITA Study) was conducted in Spain in order to estimate the coverage and factors associated with cervical cancer cytological screening. The results of this survey indicate that the rate of screening for cervical cancer in Spain is 75.6% in women between 18 and 65 years. This high rate of...

journal_title：Gynecologic oncology

authors： Puig-Tintoré LM,Torné A,Alonso I

更新日期：2008-09-01 00:00:00

abstract：INTRODUCTION:Metastatic involvement of the mediastinal lymph nodes is an extremely uncommon finding in epithelial ovarian cancers. CASE REPORT:A 63-year-old woman was admitted to hospital for dyspnoea due to an anterior mediastinal mass. The surgical biopsy showed a 6-cm metastatic lymph node with a papillary pattern,...

journal_title：Gynecologic oncology

authors： Zannoni GF,Vellone VG,Distefano MG,Fadda G,Scambia G

更新日期：2007-02-01 00:00:00

abstract：OBJECTIVE:In this investigation, we explored the hypothesis that genetic polymorphisms in the cytochrome P4501A1 (T3801C) and glutathione S-transferase classes mu and theta (GSTM1 and GSTT1) gene deletions promote the development of cervical dysplasia by moderating the activation and detoxification of polycyclic hydroc...

journal_title：Gynecologic oncology

authors： Goodman MT,McDuffie K,Hernandez B,Bertram CC,Wilkens LR,Guo C,Seifried A,Killeen J,Le Marchand L

更新日期：2001-05-01 00:00:00

abstract：OBJECTIVE:We report a case of uterine leiomyosarcoma occurring after uterine artery embolization and review the previously published cases. We estimate the incidence of sarcoma after UAE, the mean diagnostic delay in young women undergoing this procedure and review the potential and limits of preoperative procedures in...

journal_title：Gynecologic oncology

authors： Papadia A,Salom EM,Fulcheri E,Ragni N

更新日期：2007-01-01 00:00:00

abstract：:Ascitic fluid was obtained from a patient with ovarian endometrioid carcinoma. The cells obtained from the fluid were cultured in Eagle's minimum essential medium containing 15% fetal calf serum at 37 degrees C under humidified 5% CO2 and 95% air. Epithelial colonies grew rapidly in the primary culture and we were abl...

journal_title：Gynecologic oncology

authors： Uehara S,Abe H,Hoshiai H,Yajima A,Suzuki M

更新日期：1984-03-01 00:00:00

abstract：:Only one case of endometrial transitional cell carcinoma (TCC) has been previously reported in the literature. We report a second case. In both the previously reported case and in this case there was a separate focus of TCC in the adnexa. Both patients were treated with adjuvant whole pelvic radiation and are alive an...

journal_title：Gynecologic oncology

authors： Spiegel GW,Austin RM,Gelven PL

更新日期：1996-02-01 00:00:00

abstract：:Nineteen patients with stage III or IV epithelial ovarian cancer treated on a prospective randomized protocol with either adriamycin and cis-diamminedichloroplatinum or tamoxifen, adriamycin, and cis-diamminedichloroplatinum received a modified "CHAP II" regimen at the time of clinical progression of disease or the fi...

journal_title：Gynecologic oncology

authors： Schwartz PE,Keating G,Kohorn EI,Chambers JT

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND:Metformin has been associated with reduced cancer risk. The mechanisms underlying this cancer protective effect remain unknown. METHODS:"Window of opportunity" study of metformin in women with operable endometrial cancer (EC). Eleven newly diagnosed, untreated, non-diabetic patients with EC received metform...

journal_title：Gynecologic oncology

authors： Laskov I,Drudi L,Beauchamp MC,Yasmeen A,Ferenczy A,Pollak M,Gotlieb WH

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVE:The 2018 International Federation of Gynecology and Obstetrics (FIGO) staging system for cervical cancer changed from a clinical system to a clinical/pathologic/radiologic system with stages IIIC1 and IIIC2 indicating positive pelvic and para-aortic lymph nodes, respectively. We evaluated the National Cancer ...

journal_title：Gynecologic oncology

authors： McComas KN,Torgeson AM,Ager BJ,Hellekson C,Burt LM,Maurer KA,Werner TL,Gaffney DK

更新日期：2020-01-01 00:00:00

abstract：:Cancers with deficiencies in homologous recombination-mediated DNA repair (HRR) demonstrate improved clinical outcomes and increased survival. Approximately 50% of high-grade serous ovarian cancers (HGSOC) exhibit homologous recombination deficiency (HRD). HRD can be caused by germline or somatic mutations of genes in...

journal_title：Gynecologic oncology

authors： Fuh K,Mullen M,Blachut B,Stover E,Konstantinopoulos P,Liu J,Matulonis U,Khabele D,Mosammaparast N,Vindigni A

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVE:Australia's HPV vaccination and HPV-based cervical screening programs are changing the landscape in cervical cancer prevention. We aim to identify areas which can make the biggest further impact on cervical cancer burden. This protocol describes the first stage of a program of work called Pathways-Cervix that...

journal_title：Gynecologic oncology

authors： Velentzis LS,Smith MA,Simms KT,Lew JB,Hall M,Hughes S,Yuill S,Killen J,Keane A,Butler K,Darlington-Brown J,Hui H,Brotherton JML,Skinner R,Brand A,Roeske L,Heley S,Carter J,Bateson D,Frazer I,Garland SM,Guy R,H

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVE:To describe the incidence of isolated paraaortic nodal metastasis in surgically staged endometrial cancer patients with negative pelvic lymph nodes. METHODS:Using a prospectively maintained database we identified all cases of endometrial cancer that had both pelvic and aortic nodal dissection and determined ...

journal_title：Gynecologic oncology

authors： Abu-Rustum NR,Gomez JD,Alektiar KM,Soslow RA,Hensley ML,Leitao MM Jr,Gardner GJ,Sonoda Y,Chi DS,Barakat RR

更新日期：2009-11-01 00:00:00

abstract：:Treatment of 102 patients with cancer of the cervix by class II and III radical hysterectomy was reviewed to compare the operative morbidity and efficacy of class II radical hysterectomy for select cases. Of the 102 patients, 21 had a class II hysterectomy, whereas 81 patients had a class III hysterectomy. The class I...

journal_title：Gynecologic oncology

authors： Photopulos GJ,Zwaag RV

更新日期：1991-01-01 00:00:00

abstract：:Between August 1990 and January 1992, 184 patients with squamous cell carcinoma of the cervix, FIGO stage IIB-IVA, were randomized to receive either two cycles of bleomycin, ifosfamide-mesna, and cis-platinum (BIP) chemotherapy (CT) followed by radiotherapy (RT) ("CT-RT group," n = 94) or RT alone (RT group, n = 90). ...

journal_title：Gynecologic oncology

authors： Kumar L,Kaushal R,Nandy M,Biswal BM,Kumar S,Kriplani A,Singh R,Rath GK,Kochupillai V

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:Low-grade endometrial stromal sarcoma is generally an indolent tumor rich in estrogen and progesterone receptors. Objective responses to hormonal therapy, most commonly with megestrol acetate, have been reported. CASE:The patient is a 51-year-old woman who presented with low-grade endometrial stromal sarcom...

journal_title：Gynecologic oncology

authors： Maluf FC,Sabbatini P,Schwartz L,Xia J,Aghajanian C

更新日期：2001-08-01 00:00:00