Ovarian serous carcinoma presenting with mediastinal lymphadenopathy 20 months before the intraabdominal mass: role of immunohistochemistry.

abstract：OBJECTIVE:Previous studies by the Gynecologic Oncology Group have demonstrated a 7% response rate with bolus etoposide as second-line therapy in nonsquamous cell carcinoma of the cervix. Prolonged oral etoposide, which exploits the schedule dependency of this agent, has demonstrated increased activity in squamous carci...

journal_title：Gynecologic oncology

authors： Rose PG,Blessing JA,Buller RE,Mannel RS,Webster KD

更新日期：2003-05-01 00:00:00

abstract：OBJECTIVES:Intraperitoneal (IP) chemotherapy following neoadjuvant chemotherapy (NACT) and interval tumor reductive surgery (TRS) for advanced ovarian cancer is feasible, however, the impact on disease outcomes remains unclear. We compare outcomes of patients treated with IP chemotherapy versus intravenous (IV) chemoth...

journal_title：Gynecologic oncology

authors： Bixel K,Vetter M,Davidson B,Berchuck A,Cohn D,Copeland L,Fowler JM,Havrilesky L,Lee PS,O'Malley DM,Salani R,Valea F,Alvarez Secord A,Backes F

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVE:The establishment of clinical features identifying patients at a heightened risk for the development of carboplatin hypersensitivity may assist in the management of this important toxicity. Based on a previous report suggesting a history of "bee sting" allergy predicted for paclitaxel hypersensitivity, we att...

journal_title：Gynecologic oncology

authors： Markman M,Zanotti K,Kulp B,Peterson G,Markman M

更新日期：2003-06-01 00:00:00

abstract：:The objective of this study was to evaluate the prognostic value of a convenient nuclear grading system based on only the proportion of nuclei measuring more than 10 microm in length at the shortest axis in endometrial carcinomas. Of the 235 cases reviewed, 9 serous and 5 clear cell adenocarcinomas and 2 small cell ca...

journal_title：Gynecologic oncology

authors： Hachisuga T,Kawarabayashi T,Iwasaka T,Sugimori H,Kamura T,Tsuneyoshi M

更新日期：1997-04-01 00:00:00

abstract：:As gynecologic surgeons garnered a better understanding of various clinical-pathological prognostic factors, there evolved a number of modifications in the surgical approach allowing for more individualized therapy with less morbidity, while still retaining the curative potential of the radical vulvectomy operation. T...

journal_title：Gynecologic oncology

authors： Moore DH

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVE:The consequences of defective homologous recombination and other DNA repair pathways are important in disease outcomes of numerous tumor types. The objective of this study was to explore BRCA1, PARP, FANCD2, PTEN, H2AX, and ATM protein expression in endometrial cancer (EC). METHODS:PARP1, γH2AX, ATM, FANCD2,...

journal_title：Gynecologic oncology

authors： Mhawech-Fauceglia P,Wang D,Kim G,Sharifian M,Chen X,Liu Q,Lin YG,Liu S,Pejovic T

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Radiation-induced or -associated sarcoma is a rare event which has been well described in the literature. However, this entity has been infrequently described in association with genital tract malignancies. To our knowledge it has never been described in association with the management of vulvar cancer. CAS...

journal_title：Gynecologic oncology

authors： Hyde S,Uitterhoeve LJ,Schilthuis MS,ten Kate FJ,van der Velden J

更新日期：2001-05-01 00:00:00

abstract：:Aggressive cytoreductive surgery followed by combination chemotherapy for stage III ovarian carcinoma has resulted in a significant percentage of complete clinical responses. However, 30-50% of patients with no clinical evidence of disease are found to have residual carcinoma at second-look surgical reassessment. Beca...

journal_title：Gynecologic oncology

authors： Hoskins WJ,Lichter AS,Whittington R,Artman LE,Bibro MC,Park RC

更新日期：1985-03-01 00:00:00

abstract：:Radical vulvectomy using warm-knife and open-wound techniques was performed as the first step in a two-phase surgical approach in 274 patients with malignant vulvar tumors. Crude 5-year survival was registered in 133/223 (60%) patients. The complication rate was low and the hospitalization period was short (mean 16 da...

journal_title：Gynecologic oncology

authors： Simonsen E,Johnsson JE,Tropé C

更新日期：1984-01-01 00:00:00

abstract：OBJECTIVE:Management of locally advanced cervical cancer consists primarily of combination external and internal radiation. In order to investigate the impact of intracavitary brachytherapy versus interstitial brachytherapy on local tumor control, survival, and complications, we retrospectively reviewed the concomitant...

journal_title：Gynecologic oncology

authors： Monk BJ,Tewari K,Burger RA,Johnson MT,Montz FJ,Berman ML

更新日期：1997-12-01 00:00:00

abstract：:Absorbable synthetic mesh (910-polyglactin) was used to create an intestinal sling in six patients undergoing surgical staging of pelvic malignancies prior to radiation therapy. All patients had effective compartmentalization of small intestine out of the pelvis which persisted throughout the duration of radiation the...

journal_title：Gynecologic oncology

authors： Soper JT,Clarke-Pearson DL,Creasman WT

更新日期：1988-03-01 00:00:00

abstract：:Primary lymphoma of the cervix is very rare. A case report is presented and 24 cases published in the English literature are reviewed. Evaluation, staging, treatment, and prognosis of this rare tumor are discussed. ...

journal_title：Gynecologic oncology

authors： Mann R,Roberts WS,Gunasakeran S,Tralins A

更新日期：1987-01-01 00:00:00

abstract：:The purpose of this study was to evaluate the differences of blood supply in benign and malignant breast tumors by color Doppler flow measurements. The study included 471 patients, 133 with carcinomas, 325 with benign breast lesions, and 13 with mastitis. An ATL UM9/HDI was used with an electronic 10-MHz linear array ...

journal_title：Gynecologic oncology

authors： Madjar H,Sauerbrei W,Prömpeler HJ,Wolfarth R,Gufler H

更新日期：1997-03-01 00:00:00

abstract：OBJECTIVE:The goal of this work was to evaluate the involvement of gonadotropins in the regulation of adhesion of human epithelial ovarian carcinoma. We studied two pathways that were previously implicated in the metastatic implantation of ovarian carcinoma to the peritoneum, namely hyaluronan-CD44 and RGD-integrin med...

journal_title：Gynecologic oncology

authors： Schiffenbauer YS,Meir G,Maoz M,Even-Ram SC,Bar-Shavit R,Neeman M

更新日期：2002-02-01 00:00:00

abstract：OBJECTIVE:To review and summarize evidence from clinical, translational and epidemiologic studies which have examined the clinically relevant aspects of HPV type prevalence and cervical dysplasia in HIV-infected women. METHODS:Relevant studies were identified through a MEDLINE search. References of identified reports ...

journal_title：Gynecologic oncology

authors： McKenzie ND,Kobetz EN,Hnatyszyn J,Twiggs LB,Lucci JA 3rd

更新日期：2010-03-01 00:00:00

abstract：:Two-hundred and eighty-eight patients with predominately stage IIB or IIIB cervical carcinoma underwent pretreatment surgical staging including selective paraaortic lymphadenectomy (SPAL), followed by pelvic irradiation with or without paraaortic irradiation (RT). Four patients were excluded from analysis (two receive...

journal_title：Gynecologic oncology

authors： Weiser EB,Bundy BN,Hoskins WJ,Heller PB,Whittington RR,DiSaia PJ,Curry SL,Schlaerth J,Thigpen JT

更新日期：1989-06-01 00:00:00

abstract：OBJECTIVE:The presence of metastases to regional lymph nodes (LN) is the single most important risk factor in endometrial cancer. Advances in molecular biology have provided more sensitive methods for detecting micrometastasis. This was a pilot study to determine whether cytokeratin staining of LN from endometrial canc...

journal_title：Gynecologic oncology

authors： Gonzalez Bosquet J,Keeney GL,Mariani A,Webb MJ,Cliby WA

更新日期：2003-12-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to evaluate the ability of the American College of Surgeons (ACS) National Surgical Quality Improvement Program (NSQIP) surgical risk calculator to predict complications in gynecologic oncology patients undergoing laparotomy. METHODS:A chart review of patients who underwent la...

journal_title：Gynecologic oncology

authors： Rivard C,Nahum R,Slagle E,Duininck M,Isaksson Vogel R,Teoh D

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the clinical accuracy and clinical impact of positron emission tomography (PET) or positron emission tomography/computed tomography (PET/CT) in detecting and treating tumor recurrence in patients with treated uterine sarcoma. METHODS:Results of 36 patients who underwent PET or PET/CT in post-ther...

journal_title：Gynecologic oncology

authors： Park JY,Kim EN,Kim DY,Suh DS,Kim JH,Kim YM,Kim YT,Nam JH

更新日期：2008-05-01 00:00:00

abstract：:The purpose of this study was to determine the response of vulvar intraepithelial neoplasia (VIN) lesions to standard treatment methods in women infected with human immunodeficiency virus (HIV). We reviewed all cases of VIN over a 4-year period at an inner-city hospital. We reviewed the clinical records of these women...

journal_title：Gynecologic oncology

authors： Korn AP,Abercrombie PD,Foster A

更新日期：1996-06-01 00:00:00

abstract：:The methods for preoperative diagnosis and evaluation of the woman with a suspected ovarian neoplasm have evolved significantly with little or no impact on the surgical treatment, which remains removal of the abnormal ovary. Although most adnexal masses are benign, the primary goal of the diagnostic evaluation is the ...

journal_title：Gynecologic oncology

authors： Curtin JP

更新日期：1994-12-01 00:00:00

abstract：OBJECTIVES:Insomnia is common in women with ovarian cancer but there are limited prospective data on the frequency and degree of impact on patients. Our objective was to determine the prevalence of insomnia over the first three years after a diagnosis of ovarian cancer; and the relationship between insomnia and quality...

journal_title：Gynecologic oncology

authors： Ross TL,DeFazio A,Friedlander M,Grant P,Nagle CM,Williams M,Webb PM,Beesley VL,OPAL Study Group.

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:The prognosis of cancer patients with distant metastases is extremely poor. CASE:A 51-year-old Japanese woman with Stage IIIc serous cystoadenocarcinoma of the ovary achieved complete remission. At 30 and 39 months after the initiation of therapy, solitary brain and then spleen metastases without intraperit...

journal_title：Gynecologic oncology

authors： Mikami M,Suzuki A,Takehara K,Komiyama S,Ishikawa M,Hirose T

更新日期：2003-08-01 00:00:00

abstract：OBJECTIVE:The value of surgical staging of apparent early stage epithelial ovarian carcinoma (EOC) is unclear. The aim of this study was to evaluate the importance of surgical staging on the stage of disease and treatment plan. MATERIAL AND METHODS:All patients with apparent stage I EOC undergoing staging from 01/01/2...

journal_title：Gynecologic oncology

authors： Hengeveld EM,Zusterzeel PLM,Lajer H,Høgdall CK,Rosendahl M

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy and biological effects of the gemcitabine/tanespimycin combination in patients with advanced ovarian and peritoneal cancer. To assess the effect of tanespimycin on tumor cells, levels of the chaperone proteins HSP90 and HSP70 were examined in peripheral blood mononuclear cells (PBMC) ...

journal_title：Gynecologic oncology

authors： Hendrickson AE,Oberg AL,Glaser G,Camoriano JK,Peethambaram PP,Colon-Otero G,Erlichman C,Ivy SP,Kaufmann SH,Karnitz LM,Haluska P

更新日期：2012-02-01 00:00:00

abstract：OBJECTIVES:The aim of the study is to determine whether critical pathways can be implemented at an academic institution to limit cost, without compromising patient satisfaction and quality of care. PATIENTS AND METHODS:Patients undergoing a hysterectomy with either cervical or endometrial cancer were placed on specifi...

journal_title：Gynecologic oncology

authors： Ghosh K,Downs LS,Padilla LA,Murray KP,Twiggs LB,Letourneau CM,Carson LF

更新日期：2001-11-01 00:00:00

abstract：:This study evaluated the effects of cisplatin on 18 nerve conduction parameters of median, ulnar, peroneal, and sural nerves in relation to age, magnesium nadir, average magnesium, and magnesium replacement in gynecologic oncology patients. The 37 patients in this study received cisplatin (70 mg/m2) at 4-week interval...

journal_title：Gynecologic oncology

authors： Ashraf M,Riggs JE,Wearden S,Scotchel P

更新日期：1990-04-01 00:00:00

abstract：:Sclerosing stromal cell tumors of the ovary are an uncommon neoplasm that usually does not produce hormonal imbalances. Most patients showing a hormonal effect from this lesion have had menstrual cycle disturbances. Infertility and endometrial hyperplasia have also been described. One other reported case had masculini...

journal_title：Gynecologic oncology

authors： Cashell AW,Cohen ML

更新日期：1991-12-01 00:00:00

abstract：:Ovarian germ cell tumors (GCTs) are rare in adults, but are more common in adolescents and young adults. Contemporary management of ovarian GCTs is evolving as collaboration among pediatric, medical, and gynecologic oncologists increases, and studies increasingly incorporate female adult patients. Despite an improved ...

journal_title：Gynecologic oncology

authors： Veneris JT,Mahajan P,Frazier AL

更新日期：2020-08-01 00:00:00

abstract：OBJECTIVE:Cervical cancer is a disease caused in part by an infection with an oncogenic subtype of human papillomavirus (HPV). In this study we analysed all cervical cancer samples diagnosed in Iceland during two periods, 1958-1960 and 1995-1996, and asked whether significant changes in viral or immunological parameter...

journal_title：Gynecologic oncology

authors： Mikaelsdottir EK,Benediktsdottir KR,Olafsdottir K,Arnadottir T,Ragnarsson GB,Olafsson K,Sigurdsson K,Kristjansdottir GS,Imsland AK,Ogmundsdottir HM,Rafnar T

更新日期：2003-04-01 00:00:00