Primary lymphoma of the uterine cervix.

abstract：:The standard management of advanced-stage ovarian cancer has been a subject of debate, and much controversy remains as to whether patients should have primary cytoreductive surgery followed by chemotherapy or neoadjuvant chemotherapy followed by interval cytoreductive surgery. In addition, there is increasing evidence...

journal_title：Gynecologic oncology

authors： Gómez-Hidalgo NR,Martinez-Cannon BA,Nick AM,Lu KH,Sood AK,Coleman RL,Ramirez PT

更新日期：2015-06-01 00:00:00

abstract：OBJECTIVE:Collagen gel constitutes a valuable tool for the study of cell-matrix interactions; however, it is sometimes difficult to use the gel, in which tumor and stromal cells are cocultured, for immunohistochemistry, because it is easily broken during the process of fixation and embedding in paraffin, especially aft...

journal_title：Gynecologic oncology

authors： Tanaka R,Saito T,Ashihara K,Nishimura M,Mizumoto H,Kudo R

更新日期：2003-08-01 00:00:00

abstract：:Choriocarcinoma cells grown in the presence of methotrexate (MTX) developed resistance in two ways. HCCM-derived sublines (relatively high MTX resistance) produced enhanced levels of dihydrofolate reductase (DHFR) and had impaired transport of MTX. Altered transport was the primary determinant of response in CC1-deriv...

journal_title：Gynecologic oncology

authors： Sakai K,Wake N,Fujino T,Yasuda T,Kato H,Fujimoto S,Fujinaga K

更新日期：1989-07-01 00:00:00

abstract：OBJECTIVE:To evaluate C-reactive protein (CRP) serum levels as a preoperative predictive marker for ovarian cancer in patients with adnexal masses. METHODS:CRP serum levels of 1843 adnexal masses and subsequent surgery were investigated (patients with benign ovarian tumors: n=1423; borderline tumor of the ovary [BTO]:...

journal_title：Gynecologic oncology

authors： Reiser E,Aust S,Seebacher V,Reinthaller A,Helmy-Bader S,Schwameis R,Grimm C,Polterauer S

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:Cone margin status has been reported to be the most important predictor of residual disease in patients with cervical intraepithelial neoplasia (CIN) undergoing electrosurgical excisional treatment. The primary aim of this study of patients treated with electrosurgical conization was to evaluate the associati...

journal_title：Gynecologic oncology

authors： Costa S,De Nuzzo M,Infante FE,Bonavita B,Marinelli M,Rubino A,Rambelli V,Santini D,Cristiani P,Bucchi L

更新日期：2002-04-01 00:00:00

abstract：:The ovary is a relatively frequent site of metastasis from malignant neoplasia arising elsewhere in the body, the majority of these originating from the GI tract. The best known tumor of this type is signet-ring cell adenocarcinoma (Krukenberg tumor) of gastric origin. The gall bladder and bile ducts are rare sources ...

journal_title：Gynecologic oncology

authors： Lashgari M,Behmaram B,Hoffman JS,Garcia J

更新日期：1992-11-01 00:00:00

abstract：:The alpha-emitter 211At was bound to polymer microspheres with a diameter of 1.8 microns. The distributions in mice of intraperitoneally injected 211At microspheres, 90Y silicate colloid, and 32P chromic phosphate colloid were compared. The microspheres with 211At spread rapidly in the peritoneal cavity and remained m...

journal_title：Gynecologic oncology

authors： Vergote I,Larsen RH,De Vos L,Winderen M,Ellingsen T,Bjørgum J,Hoff P,Aas M,Tropé C,Nustad K

更新日期：1992-12-01 00:00:00

abstract：:The CA 125 radioimmunoassay has been increasingly used to monitor the course of patients with ovarian epithelial carcinomas. The purpose of this report is to describe our experience in the use of this assay and to better define its clinical utility. Fifty-one patients had serum CA 125 follow-up during primary chemothe...

journal_title：Gynecologic oncology

authors： Podczaski E,Whitney C,Manetta A,Larson JE,Kirk J,Stevens CW,Lyter J,Mortel R

更新日期：1989-05-01 00:00:00

abstract：:Thirty-two patients with Stage III or IV epithelial ovarian cancer and residual tumor volumes in excess of 2 cm in diameter after initial debulking were treated with platinum and cyclophosphamide chemotherapy. Twenty-seven patients (84%) received at least six courses of chemotherapy. Six patients developed grade 3 or ...

journal_title：Gynecologic oncology

authors： Gallion HH,van Nagell JR,Donaldson ES,Hanson MB,Kryscio RJ

更新日期：1987-06-01 00:00:00

abstract：OBJECTIVE:Mesenchymal (MES) subtype of high-grade serous ovarian cancer (HGSOC) is associated with worse outcomes including survival and resectability compared with other molecular subtypes. Molecular subtypes have historically been derived from 'tumor', consisting of both cancer and stromal cells. We sought to determi...

journal_title：Gynecologic oncology

authors： Zhang Q,Wang C,Cliby WA

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:The aim of this study was to report an exceptional case of a patient presenting with intracaval and intracardiac leiomyomatosis treated by combined surgical and medical treatment. CASE:A 48-year-old presented with intracaval and intracardiac leiomyomatosis (IL) discovered 6 years following a total hysterect...

journal_title：Gynecologic oncology

authors： Morice P,Chapelier A,Dartevelle P,Castaigne D,Lhommé C

更新日期：2001-11-01 00:00:00

abstract：OBJECTIVE:Despite the fact that endometrial cancer commonly occurs in elderly women, little is known about the outcome of the oldest old, those > 80 years of age. We examined the patterns of care and outcome of the oldest old women with endometrial cancer. METHODS:An analysis of women > 65 years of age with endometrio...

journal_title：Gynecologic oncology

authors： Wright JD,Lewin SN,Barrena Medel NI,Sun X,Burke WM,Deutsch I,Herzog TJ

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:We aim to describe the false negative (FN) and false positive (FP) rates of preoperative cross-sectional imaging (PCI) prior to radical surgery for cervical cancer. METHODS:A retrospective cohort study of patients who underwent radical hysterectomy for early-stage cervical cancer from January 2010 until Dece...

journal_title：Gynecologic oncology

authors： Staley SA,Tucker KR,Gehrig PA,Clark LH

更新日期：2021-02-01 00:00:00

abstract：OBJECTIVE:Carcinosarcoma (CS) of the uterus or ovary is a rare, biphasic tumor comprising epithelial and mesenchymal elements, and exhibits more aggressive clinical features than its carcinoma counterpart. Four molecular subtypes of CS were recently established based on genomic aberration profiles (POLE, MSI, CNH, and ...

journal_title：Gynecologic oncology

authors： Gotoh O,Kiyotani K,Chiba T,Sugiyama Y,Takazawa Y,Nemoto K,Kato K,Tanaka N,Nomura H,Hasegawa K,Fujiwara K,Takamatsu S,Matsumura N,Noda T,Mori S

更新日期：2021-02-01 00:00:00

abstract：:Sialosyl-Tn (S-Tn) antigen, a cancer-related antigen, was expressed in 56.3% (36 of 64 cases) of the common epithelial carcinoma tissues. This antigen was moderately to strongly expressed in 83.3% (15 of 18 cases) of the mucinous adenocarcinomas. In contrast, it was weakly expressed in 31.3% (5 of 16 cases) of the ser...

journal_title：Gynecologic oncology

authors： Ryuko K,Iwanari O,Kitao M,Moriwaki S

更新日期：1993-05-01 00:00:00

abstract：OBJECTIVE:To investigate the influence of human anti-mouse antibodies (HAMA) on serial CA 125 measurements in serum of patients with epithelial ovarian cancer following single intraperitoneal (IP) therapy with Yttrium-90-labeled human milk fat globule 1 murine monoclonal antibody ((90)Y-muHMFG1) as part of a large inte...

journal_title：Gynecologic oncology

authors： Oei AL,Sweep FC,Massuger LF,Olthaar AJ,Thomas CM

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Nongestational pure ovarian choriocarcinoma is a rare malignancy with only 29 cases described to date. CASE:We describe a case associated with mature cystic teratoma of the contralateral ovary. Details of all 30 cases including clinical features, associations, surgicopathological findings, operative procedu...

journal_title：Gynecologic oncology

authors： Goswami D,Sharma K,Zutshi V,Tempe A,Nigam S

更新日期：2001-02-01 00:00:00

abstract：OBJECTIVES:To determine if SAHA, a histone deacetylase inhibitor, decreases ovarian cancer cell viability when combined with paclitaxel in vitro, and to explore molecular alterations of combined paclitaxel+SAHA treatment. METHODS:SKOV3 and Hey ovarian cancer cell lines were treated for 24 h with paclitaxel, then re-tr...

journal_title：Gynecologic oncology

authors： Dietrich CS 3rd,Greenberg VL,DeSimone CP,Modesitt SC,van Nagell JR,Craven R,Zimmer SG

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:The objective of this study is to compare survival of Asian (AS), American Indian/Alaskan Native (AI/AN) and non-Hispanic white (NHW) women with endometrial adenocarcinoma (EC). METHODS:Patients with EC were identified from the Surveillance, Epidemiology, and End Results program from 1988 to 2009. Kaplan-Mei...

journal_title：Gynecologic oncology

authors： Mahdi H,Schlick CJ,Kowk LL,Moslemi-Kebria M,Michener C

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVE:Vaccination of young women (15-25 years of age) against human papillomavirus (HPV) has been shown to be very efficacious in preventing the development of moderate or severe cervical precancerous lesions associated with HPV-16 or -18. As the highest rates of new infections with high-risk (i.e., oncogenic) HPV ...

journal_title：Gynecologic oncology

authors： Castellsagué X,Schneider A,Kaufmann AM,Bosch FX

更新日期：2009-12-01 00:00:00

abstract：:In approximately ten months' time, the novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected over 34 million people and caused over one million deaths worldwide. The impact of this virus on our health, relationships, and careers is difficult to overstate. As the economic realiti...

journal_title：Gynecologic oncology

authors： Ferriss JS,Rose S,Rungruang B,Urban R,Spencer R,Uppal S,Sinno AK,Duska L,Walsh C

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVES:The differential metabolic phenotype observed between malignant and non-transformed cells may constitute a biochemical basis for therapeutic intervention. Increased glucose uptake is one of the major metabolic changes found in malignant tumors, a process that is mediated by glucose transporters such as Glut1...

journal_title：Gynecologic oncology

authors： Wahl H,Daudi S,Kshirsagar M,Griffith K,Tan L,Rhode J,Liu JR

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:To compare the efficacy of chemotherapy (C) combined with bevacizumab (Bev) versus Bev alone in recurrent, heavily pretreated epithelial ovarian cancer (EOC). METHODS:A multicenter analysis of patients treated from 2004 to 2011 was performed. Demographic, treatment, response, and adverse event information w...

journal_title：Gynecologic oncology

authors： Fuh KC,Secord AA,Bevis KS,Huh W,ElNaggar A,Blansit K,Previs R,Tillmanns T,Kapp DS,Chan JK

更新日期：2015-12-01 00:00:00

abstract：:Between 1965 and 1988, 125 patients with primary invasive vaginal carcinoma were treated with radiation therapy at the Center of Oncology in Kraków. Twenty-two superficial stage I patients received radium or cesium intracavitary radiation alone. The remaining 11 patients with stage I disease whose lesions were either ...

journal_title：Gynecologic oncology

authors： Urbański K,Kojs Z,Reinfuss M,Fabisiak W

更新日期：1996-01-01 00:00:00

abstract：OBJECTIVES:Participation in clinical and basic science research is emphasized in gynecologic oncology training. We sought to identify trends in adherence to expected research practices and reasons for non-adherence among gynecologic oncology fellows. METHODS:An anonymous 31-question online survey assessing academic be...

journal_title：Gynecologic oncology

authors： Moulton LJ,Michener CM,Levinson K,Cobb L,Tseng J,Jernigan A

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVE:Uterine papillary serous carcinoma (UPSC) is a variant of endometrial cancer that is aggressive and associated with poor outcomes. We sought to evaluate the cost effectiveness of carboplatin/paclitaxel alone versus carboplatin/paclitaxel with trastuzumab among patients with Her2/neu-positive advanced or recur...

journal_title：Gynecologic oncology

authors： Batman S,Bohn J,Weisenberger MW,Hersh A,Bruegl A,Caughey A,Winter W 3rd

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVE:Epithelial ovarian cancer continues to be the deadliest gynecologic malignancy. Patients with both diabetes mellitus and obesity have poorer outcomes, yet research correlating metabolic abnormalities, such as metabolic syndrome, to ovarian cancer risk and outcomes is lacking. This article reviews the literatu...

journal_title：Gynecologic oncology

authors： Craig ER,Londoño AI,Norian LA,Arend RC

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVES:MKK4 is a metastasis suppressor that is downregulated in some ovarian cancers. We sought to investigate whether promoter methylation, loss of heterozygosity, or changes in phosphorylation are involved in MKK4 dysregulation during ovarian carcinogenesis. METHODS:Bisulfite sequencing was used to determine MKK...

journal_title：Gynecologic oncology

authors： Spillman MA,Lacy J,Murphy SK,Whitaker RS,Grace L,Teaberry V,Marks JR,Berchuck A

更新日期：2007-05-01 00:00:00

abstract：:Adriamycin (50 mg/m2) and cis-diamminedichloroplatinum (50 mg/m2) were administered every 21 days to treat metastatic endometrial adenocarcinoma. This regimen resulted in three responses (one complete and two partial) in nine women (33%). Most patients had moderate or severe hematologic and gastrointestinal toxicity. ...

journal_title：Gynecologic oncology

authors： Seltzer V,Vogl SE,Kaplan BH

更新日期：1984-11-01 00:00:00

abstract：BACKGROUND:Radical vaginal trachelectomy (RVT) is an acceptable approach when applied toward a select group of patients with early stage cervical carcinoma. It is less invasive, can maintain fertility, and can be ideal in patients with significant comorbid factors compared to abdominal approaches. A small subset of pat...

journal_title：Gynecologic oncology

authors： Mendez LE,Penalver M,McCreath W,Bejarano P,Angioli R

更新日期：2002-06-01 00:00:00