Trastuzumab with carboplatin/paclitaxel for treatment of advanced stage and recurrent uterine papillary serous carcinoma: A cost-effectiveness analysis.

abstract：:The distribution of colon--ovarian tumor antigen (COTA) and colon-specific antigen (CSA) was studied immunohistochemically in gynecologic tumors. The antigens were absent in the serous benign tumors of the ovary and in the normal ovarian tissues, whereas they were detected in some of the mucinous benign tumors. COTA a...

journal_title：Gynecologic oncology

authors： Ueda G,Shimizu C,Saito J,Tanaka Y,Inoue M,Tanizawa O

更新日期：1989-10-01 00:00:00

abstract：OBJECTIVES:To identify an indicator that can predict tumor cell spread beyond the uterine corpus. METHODS:We studied clinicopathology and immunohistochemistry of 12 cases of PSTT. Two cases of epithelioid trophoblastic tumor (ETT) were included as reference cases. For immunohistochemistry, antibodies against Ki-67, p5...

journal_title：Gynecologic oncology

authors： Nagai Y,Kamoi S,Matsuoka T,Hata A,Jobo T,Ogasawara T,Aoki Y,Ohira S,Okamoto T,Nakamoto T,Kanda K,Matsui H

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVE:A multicenter phase II trial was conducted to assess the efficacy and toxicity of concurrent chemoradiotherapy (CCRT) with high-dose-rate intracavitary brachytherapy (HDR-ICBT) using a low cumulative prescribed dose schedule in patients with locally advanced uterine cervical cancer. METHODS:The Japanese Gyne...

journal_title：Gynecologic oncology

authors： Toita T,Kitagawa R,Hamano T,Umayahara K,Hirashima Y,Aoki Y,Oguchi M,Mikami M,Takizawa K,Cervical Cancer (Vulva Cancer) Committee of Japanese Gynecologic Oncology Group (JGOG).

更新日期：2012-08-01 00:00:00

abstract：:The patient described synchronous mucinous tumors of the cervix and ovary and concurrent annular tubules, but without the classical stigmata of Peutz-Jeghers syndrome. The cervical tumor was an invasive mucinous adenocarcinoma with mixed components of minimal deviation and less-well-differentiated endometrioid morphol...

journal_title：Gynecologic oncology

authors： Matseoane S,Moscovic E,Williams S,Huang JC

更新日期：1991-12-01 00:00:00

abstract：OBJECTIVE:To help determine whether global collaborations for prospective gynecologic surgery trials should include hospitals in developing countries, we compared surgical and oncologic outcomes of patients undergoing laparoscopic radical hysterectomy at a large comprehensive cancer center in the United States and a ca...

journal_title：Gynecologic oncology

authors： Pareja R,Nick AM,Schmeler KM,Frumovitz M,Soliman PT,Buitrago CA,Borrero M,Angel G,Reis RD,Ramirez PT

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVES:The aim of this study is to determine the impact of obesity on surgical and oncologic outcomes after primary debulking surgery (PDS) in advanced epithelial ovarian cancer (EOC). METHODS:Women with stage IIIC/IV EOC who underwent PDS with curative intent between 1/2/2003 and 12/30/2011 were included. Patient...

journal_title：Gynecologic oncology

authors： Kumar A,Bakkum-Gamez JN,Weaver AL,McGree ME,Cliby WA

更新日期：2014-10-01 00:00:00

abstract：:Ninety-two patients with early invasive carcinoma of the cervix (5 mm or less) treated between July 1977 and June 1990 are reviewed. Eighty patients had squamous cell carcinomas and 12 had adenocarcinomas. The diagnosis was established by conization in 77 of 92 (83.6%) patients. Thirty-six patients (39%) had a depth o...

journal_title：Gynecologic oncology

authors： Jones WB,Mercer GO,Lewis JL Jr,Rubin SC,Hoskins WJ

更新日期：1993-10-01 00:00:00

abstract：OBJECTIVE:Human papillomavirus (HPV) infection play a significant role in cervical carcinogenesis, and HPV oncoprotein E7 has important functions in the formation and maintenance of cervical cancers. Interleukin-12 (IL-12) has been reported to induce cellular immune responses, and has also been demonstrated to suppress...

journal_title：Gynecologic oncology

authors： Jin HS,Park EK,Lee JM,NamKoong SE,Kim DG,Lee YJ,Jun HJ,Han BD,Bae SM,Ahn WS

更新日期：2005-05-01 00:00:00

abstract：UNLABELLED:Despite the publication of two dozen observational epidemiological studies investigating the association between recreational physical activity (RPA) and epithelial ovarian cancer (EOC) risk and survival over the past two decades, taken collectively, data from retrospective and prospective studies are mixed ...

journal_title：Gynecologic oncology

authors： Cannioto RA,Moysich KB

更新日期：2015-06-01 00:00:00

abstract：:The cell line HTOA was established from a well-differentiated human ovarian serous cystadenocarcinoma. This line grew well and without interruption for 51 months and was subcultivated over 130 times. The cells were epithelial in shape, and neoplastic and pleomorphic features, a jigsaw puzzle-like arrangement, desmosom...

journal_title：Gynecologic oncology

authors： Ishiwata I,Ishiwata C,Soma M,Nozawa S,Ishikawa H

更新日期：1987-03-01 00:00:00

abstract：:A 46-year-old women presented with an inoperable low-grade endometrial stromal sarcoma. Two doses of Depo-Lupron, 7.5 mg, and Megace, 160 mg/day, were given to control uterine bleeding and shrink the tumor mass. In 9 weeks, significant reduction in the tumor occurred allowing for surgical resection. Total abdominal hy...

journal_title：Gynecologic oncology

authors： Scribner DR Jr,Walker JL

更新日期：1998-12-01 00:00:00

abstract：OBJECTIVES:A prior clinical trial on early-stage high risk ovarian cancer showed a lower recurrence rate in those treated with six vs. three cycles of chemotherapy. We proposed to identify subsets of patients who may benefit from more cycles of chemotherapy. METHODS:Outcomes of patients who underwent six vs. three cyc...

journal_title：Gynecologic oncology

authors： Chan JK,Tian C,Fleming GF,Monk BJ,Herzog TJ,Kapp DS,Bell J

更新日期：2010-03-01 00:00:00

abstract：:Cyclin E1 (CCNE1) gene amplification occurs in approximately 20% of ovarian high grade serous carcinoma (HGSC) and is associated with chemotherapy resistance and, in some studies, overall poor prognosis. The role of cyclin E1 in inducing S phase entry relies upon its interactions with cyclin dependent kinases (CDK), s...

journal_title：Gynecologic oncology

authors： Kanska J,Zakhour M,Taylor-Harding B,Karlan BY,Wiedemeyer WR

更新日期：2016-10-01 00:00:00

abstract：OBJECTIVE:We assessed the antineoplastic effect and adverse reactions of paclitaxel monotherapy with paclitaxel 210 mg/m(2) given every 3 weeks by 3-h infusion on patients with endometrial cancer given as a 3-h infusion. METHODS:This study was a multi-center, open-label phase II clinical trial of paclitaxel 210 mg/m(2...

journal_title：Gynecologic oncology

authors： Hirai Y,Hasumi K,Onose R,Kuramoto H,Kuzuya K,Hatae M,Ochiai K,Nozawa S,Noda K

更新日期：2004-08-01 00:00:00

abstract：:The clinical-pathologic records of 178 women with stage IB squamous cell carcinoma treated by radical hysterectomy and pelvic node dissection were reviewed to assess prognostic factors and outcome in relation to adjunctive pelvic radiation. Among 32 women with pelvic nodes metastases, 19 treated with adjunctive radiat...

journal_title：Gynecologic oncology

authors： Remy JC,di Maio T,Fruchter RG,Sedlis A,Boyce JG,Sohn CK,Rotman M

更新日期：1990-08-01 00:00:00

abstract：:One of the most prevalent potential therapeutic targets for women with endometrioid endometrial cancer (EC) is the estrogen receptor (ER)/progesterone receptor (PR) pathway. Despite a high proportion of endometrioid ECs being ER and/or PR positive, endocrine therapy is only effective in a minority of women with EC and...

journal_title：Gynecologic oncology

authors： Jerzak KJ,Duska L,MacKay HJ

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVES:The impact of diffusion-weighted imaging (DWI) and apparent diffusion coefficients (ADCs) of MR imaging on the evaluation of residual Uterine Cervical Carcinoma after Radiation Therapy, in addition to conventional MR images. METHODS:Fourty-nine women presenting with a uterine cervical cancer were examined w...

journal_title：Gynecologic oncology

authors： Levy A,Caramella C,Chargari C,Medjhoul A,Rey A,Zareski E,Boulet B,Bidault F,Dromain C,Balleyguier C

更新日期：2011-10-01 00:00:00

abstract：PURPOSE:To determine overall survival and progression-free survival among patients with high-risk, stage III and IV endometrial cancer who receive paclitaxel and carboplatin (TC) after complete tumor resection. PATIENTS AND METHODS:Patients with stage III/IV endometrial cancer with less than 2 cm of disease after surg...

journal_title：Gynecologic oncology

authors： Sovak MA,Hensley ML,Dupont J,Ishill N,Alektiar KM,Abu-Rustum N,Barakat R,Chi DS,Sabbatini P,Spriggs DR,Aghajanian C

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Primary vaginal adenosarcomas are extremely rare, and typical adenosarcomas are of low malignancy. However, aggressive forms with sarcomatous overgrowth have been reported, those appear to have a poor prognosis. CASE:A 52-year-old woman who had undergone prior surgery for uterine leiomyoma and an ovarian cy...

journal_title：Gynecologic oncology

authors： Toyoshima M,Akahira J,Moriya T,Hayakawa S,Yaegashi N

更新日期：2004-12-01 00:00:00

abstract：:MicroRNA molecules are small, single-stranded RNA molecules that function to regulate networks of genes. They play important roles in normal female reproductive tract biology, as well as in the pathogenesis and progression of epithelial ovarian cancer. DROSHA, DICER, and Argonaute proteins are components of the microR...

journal_title：Gynecologic oncology

authors： Wang X,Ivan M,Hawkins SM

更新日期：2017-11-01 00:00:00

abstract：:Between 1971 and 1979, seventy-four patients with metastatic or advanced recurrent sarcoma of uterine origin were treated with combination chemotherapy consisting of vincristine, actinomycin D, and cyclophosphamide (Cytoxan). The probability of survival at 2 and 5 years was 23 and 15%, respectively. The response rate ...

journal_title：Gynecologic oncology

authors： Hannigan EV,Freedman RS,Elder KW,Rutledge FN

更新日期：1983-04-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of interleukin-7 (IL-7) gene transfection into an established ovarian carcinoma cell line (SKOV3) in vitro and evaluate the tumorigenicity of SKOV3-IL-7 in severe combined immunodeficient (SCID) mice. METHODS:IL-7 gene was transfected into SKOV3 cells by liposome. IL-7 mRNA and prot...

journal_title：Gynecologic oncology

authors： Xie X,Ye DF,Chen HZ,Lu WG,Fu YF,Cheng B,Zhu H

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:The presence of cardiac metastasis from cervical carcinoma is extremely rare. The diagnosis is made almost exclusively postmortem. There are few cases of premortem diagnosis, and it is believed that when cardiac metastasis are found in vivo, the prognosis is extremely poor. Due to the rarity of this conditio...

journal_title：Gynecologic oncology

authors： Lemus JF,Abdulhay G,Sobolewski C,Risch VR

更新日期：1998-06-01 00:00:00

abstract：OBJECTIVE:Cervical cancer is a disease caused in part by an infection with an oncogenic subtype of human papillomavirus (HPV). In this study we analysed all cervical cancer samples diagnosed in Iceland during two periods, 1958-1960 and 1995-1996, and asked whether significant changes in viral or immunological parameter...

journal_title：Gynecologic oncology

authors： Mikaelsdottir EK,Benediktsdottir KR,Olafsdottir K,Arnadottir T,Ragnarsson GB,Olafsson K,Sigurdsson K,Kristjansdottir GS,Imsland AK,Ogmundsdottir HM,Rafnar T

更新日期：2003-04-01 00:00:00

abstract：:Three hundred and sixty-two cases of primary vaginal carcinoma were treated at the Irradiation Department of the University Clinic for Obstetrics and Gynecology, Vienna, from 1950 to 1977. As the method of choice an individually dosed, fractioned, and protracted radium-telecobalt therapy was employed. Comparing the la...

journal_title：Gynecologic oncology

authors： Kucera H,Langer M,Smekal G,Weghaupt K

更新日期：1985-05-01 00:00:00

abstract：OBJECTIVES:There is uncertainty surrounding the prognostic value and clinical utility of peritoneal cytology in endometrial cancer. Our primary objective was to determine if positive cytology is associated with disease-free and overall survival in women treated surgically for endometrial cancer, specifically those with...

journal_title：Gynecologic oncology

authors： Scott SA,van der Zanden C,Cai E,McGahan CE,Kwon JS

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVES:Vaginal reconstruction following pelvic exenteration is an important aspect of the physical and psychological rehabilitation of women after radical surgery for pelvic malignancies. The choice of techniques is vast, and proper patient and surgical selection is important for obtaining satisfactory functional a...

journal_title：Gynecologic oncology

authors： Mirhashemi R,Averette HE,Lambrou N,Penalver MA,Mendez L,Ghurani G,Salom E

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Sertoli-Leydig cell tumors (SLCT) constitute only 0.5% of all primary ovarian neoplasms. We report a unique diagnostic method (selective laparoscopic venous sampling) and a rare case of a contralateral second primary tumor. CASE:A 14-year-old female presented with hyperandrogenic complaints and an increased...

journal_title：Gynecologic oncology

authors： White LC,Buchanan KD,O'Leary TD,Carlan SJ,Boothby R

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVES:Six cycles of consolidation chemotherapy have become the standard for ovarian cancer treatment regimen following primary cytoreduction, yet with neoadjuvant chemotherapy (NAC), only 3 consolidation cycles are used. This study examines the effects of number of chemotherapy cycles in women with ovarian cancer ...

journal_title：Gynecologic oncology

authors： Altman AD,McGee J,May T,Lane K,Lu L,Xu W,Ghatage P,Rosen B

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:Some authors have recommended the use of diagnostic laparoscopy as a pretreatment assessment step for conservative hormonal treatment in young women with endometrial cancer. The aim of this study was to determine the incidence of synchronous primary cancer of the endometrium and ovary in young women. METHODS...

journal_title：Gynecologic oncology

authors： Song T,Seong SJ,Bae DS,Suh DH,Kim DY,Lee KH,Lim MC,Lee TS

更新日期：2013-12-01 00:00:00