Sarcoma in association with multimodality management of vulvar cancer: two case reports.

Abstract:

BACKGROUND:Radiation-induced or -associated sarcoma is a rare event which has been well described in the literature. However, this entity has been infrequently described in association with genital tract malignancies. To our knowledge it has never been described in association with the management of vulvar cancer. CASES:. Two different cases of sarcoma developing after primary management for vulvar cancer are presented, the first being a case of angiosarcoma developing in the lower abdominal wall 36 months after initial therapy and the second a case of fibrosarcoma developing on the vulva 7 years after multimodality treatment. CONCLUSION:Radiation-associated sarcoma after treatment for vulvar carcinoma is a rare event. A multimodality treatment of carcinoma of the vulva should not be withheld because of fear of sarcomagenesis.

journal_name

Gynecol Oncol

journal_title

Gynecologic oncology

authors

Hyde S,Uitterhoeve LJ,Schilthuis MS,ten Kate FJ,van der Velden J

doi

10.1006/gyno.2001.6139

subject

Has Abstract

pub_date

2001-05-01 00:00:00

pages

320-3

issue

2

eissn

0090-8258

issn

1095-6859

pii

S0090-8258(01)96139-6

journal_volume

81

pub_type

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