Radical vulvectomy with warm-knife and open-wound techniques in vulvar malignancies.

Abstract:

:Radical vulvectomy using warm-knife and open-wound techniques was performed as the first step in a two-phase surgical approach in 274 patients with malignant vulvar tumors. Crude 5-year survival was registered in 133/223 (60%) patients. The complication rate was low and the hospitalization period was short (mean 16 days).

journal_name

Gynecol Oncol

journal_title

Gynecologic oncology

authors

Simonsen E,Johnsson JE,Tropé C

doi

10.1016/0090-8258(84)90056-8

subject

Has Abstract

pub_date

1984-01-01 00:00:00

pages

22-31

issue

1

eissn

0090-8258

issn

1095-6859

journal_volume

17

pub_type

杂志文章
  • Ovarian serous carcinoma presenting with mediastinal lymphadenopathy 20 months before the intraabdominal mass: role of immunohistochemistry.

    abstract:INTRODUCTION:Metastatic involvement of the mediastinal lymph nodes is an extremely uncommon finding in epithelial ovarian cancers. CASE REPORT:A 63-year-old woman was admitted to hospital for dyspnoea due to an anterior mediastinal mass. The surgical biopsy showed a 6-cm metastatic lymph node with a papillary pattern,...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2006.09.030

    authors: Zannoni GF,Vellone VG,Distefano MG,Fadda G,Scambia G

    更新日期:2007-02-01 00:00:00

  • Contracting for professional service agreements.

    abstract::A review of several professional service agreements (PSA) of managed care organizations which contract with gynecologic oncologists in the Southern California area demonstrates several distinct patterns of practice restrictions and financial benefits which can help guide the physician who is considering signing such a...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1006/gyno.1995.1204

    authors: Berman ML

    更新日期:1995-08-01 00:00:00

  • Epithelial ovarian carcinoma in patients with intersex disorders: the role of pituitary gonadotropins in ovarian tumorigenesis.

    abstract::The common epithelial tumors of the human ovary have rarely been found in the gonads of intersex patients with gonadal dysgenesis or true hermaphroditism. This report describes a patient with ovarian serous cystadenocarcinoma and mixed gonadal dysgenesis (45,X/46,XY) and reviews other reported cases. Intersex patients...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/0090-8258(86)90306-9

    authors: Miller DS,Teng NN,Ballon SC

    更新日期:1986-07-01 00:00:00

  • Disease persistence in patients with cervical intraepithelial neoplasia undergoing electrosurgical conization.

    abstract:OBJECTIVE:Cone margin status has been reported to be the most important predictor of residual disease in patients with cervical intraepithelial neoplasia (CIN) undergoing electrosurgical excisional treatment. The primary aim of this study of patients treated with electrosurgical conization was to evaluate the associati...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1006/gyno.2001.6579

    authors: Costa S,De Nuzzo M,Infante FE,Bonavita B,Marinelli M,Rubino A,Rambelli V,Santini D,Cristiani P,Bucchi L

    更新日期:2002-04-01 00:00:00

  • Adjuvant chemotherapy as treatment of high-risk stage I and II endometrial cancer.

    abstract:OBJECTIVE:This study was performed to define the subgroups of patients who benefit from postoperative adjuvant chemotherapy in stage I and II endometrial carcinoma. METHODS:A retrospective review of 170 International Federation of Gynecology and Obstetrics (FIGO) stage I and II endometrial carcinoma patients treated b...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2004.05.040

    authors: Aoki Y,Watanabe M,Amikura T,Obata H,Sekine M,Yahata T,Fujita K,Tanaka K

    更新日期:2004-08-01 00:00:00

  • Predictors of optimal cytoreduction in patients with newly diagnosed advanced-stage epithelial ovarian cancer: Time to incorporate laparoscopic assessment into the standard of care.

    abstract::The standard management of advanced-stage ovarian cancer has been a subject of debate, and much controversy remains as to whether patients should have primary cytoreductive surgery followed by chemotherapy or neoadjuvant chemotherapy followed by interval cytoreductive surgery. In addition, there is increasing evidence...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,评审

    doi:10.1016/j.ygyno.2015.03.049

    authors: Gómez-Hidalgo NR,Martinez-Cannon BA,Nick AM,Lu KH,Sood AK,Coleman RL,Ramirez PT

    更新日期:2015-06-01 00:00:00

  • Minimal change disease in a patient with ovarian papillary serous carcinoma.

    abstract:BACKGROUND:Nephrotic syndrome (NS) is rarely associated with ovarian tumor. Only five cases of NS with pathologic diagnosis have been reported in patients with ovarian tumors. However, the association between minimal change disease (MCD) and ovarian tumor has not been previously reported. CASE:A 55-year-old woman pres...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2004.02.022

    authors: Ryu DR,Yoo TH,Kim YT,Jeong HJ,Cho NH,Kang SW

    更新日期:2004-05-01 00:00:00

  • Differential induction of apoptosis by tumor necrosis factor-related apoptosis-inducing ligand in human ovarian carcinoma cells.

    abstract:OBJECTIVES:In this study, we examine the sensitivity of a panel of ovarian carcinoma cells, which includes four primary ovarian cancer cell samples, and four normal ovarian epithelium samples to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). We also examine the intracellular regulation of TRAIL-mediat...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2004.03.029

    authors: Lane D,Cartier A,L'Espérance S,Côté M,Rancourt C,Piché A

    更新日期:2004-06-01 00:00:00

  • The significance of perineural invasion in early-stage cervical cancer.

    abstract:INTRODUCTION:Cervical cancer spreads directly and through lymphatic and vascular channels. Perineural invasion is an alternative method of spread. Several risk factors portend poor prognosis and inform management decisions regarding adjuvant therapy. OBJECTIVE:To evaluate the incidence and significance of PNI in early...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2011.08.028

    authors: Elsahwi KS,Barber E,Illuzzi J,Buza N,Ratner E,Silasi DA,Santin AD,Azodi M,Schwartz PE,Rutherford TJ

    更新日期:2011-12-01 00:00:00

  • PD-1 blockade in recurrent or metastatic cervical cancer: Data from cemiplimab phase I expansion cohorts and characterization of PD-L1 expression in cervical cancer.

    abstract:OBJECTIVES:To characterize the safety, tolerability, and anti-tumor activity of cemiplimab as monotherapy or in combination with hypofractionated radiation therapy (hfRT) in patients with recurrent or metastatic cervical cancer. To determine the association between histology and programmed death-ligand 1 (PD-L1) expres...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2020.08.026

    authors: Rischin D,Gil-Martin M,González-Martin A,Braña I,Hou JY,Cho D,Falchook GS,Formenti S,Jabbour S,Moore K,Naing A,Papadopoulos KP,Baranda J,Fury W,Feng M,Stankevich E,Li J,Yama-Dang NA,Yoo SY,Lowy I,Mathias M,Fury

    更新日期:2020-11-01 00:00:00

  • Clinically apparent early stage invasive epithelial ovarian carcinoma: should all be treated similarly?

    abstract:OBJECTIVES:The role of adjuvant therapy in patients with early stage ovarian carcinoma has not been clearly defined. Most randomized trials examining this issue have not used the vigorous staging exploration accepted as today's standard. This report examines the natural history of patients after surgically documented s...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1006/gyno.1999.5440

    authors: Le T,Krepart GV,Lotocki RJ,Heywood MS

    更新日期:1999-08-01 00:00:00

  • Survival of women diagnosed with malignant, mixed mullerian tumors of the ovary (OMMMT).

    abstract:OBJECTIVE:To analyze the survival of women with malignant, mixed mullerian tumors of the ovary (OMMMT) compared to women with epithelial ovarian cancer (EOC). METHODS:Data from the Surveillance, Epidemiology and End Results (SEER) Program on 14025 women diagnosed with primary invasive ovarian cancer between 1988 and 1...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2004.02.016

    authors: Barnholtz-Sloan JS,Morris R,Malone JM Jr,Munkarah AR

    更新日期:2004-05-01 00:00:00

  • Expression of DNA repair proteins in endometrial cancer predicts disease outcome.

    abstract:OBJECTIVE:The consequences of defective homologous recombination and other DNA repair pathways are important in disease outcomes of numerous tumor types. The objective of this study was to explore BRCA1, PARP, FANCD2, PTEN, H2AX, and ATM protein expression in endometrial cancer (EC). METHODS:PARP1, γH2AX, ATM, FANCD2,...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2014.02.002

    authors: Mhawech-Fauceglia P,Wang D,Kim G,Sharifian M,Chen X,Liu Q,Lin YG,Liu S,Pejovic T

    更新日期:2014-03-01 00:00:00

  • Postsurgical surveillance of patients with FIGO stage I/II endometrial adenocarcinoma.

    abstract:OBJECTIVE:To examine the effect of postsurgical surveillance on survival of patients with FIGO stage I/II endometrial adenocarcinoma. METHODS:We examined the records of 354 patients who underwent primary surgical therapy for FIGO stage I/II endometrial adenocarcinoma. In patients who developed recurrent disease, we de...

    journal_title:Gynecologic oncology

    pub_type: 临床试验,杂志文章

    doi:10.1006/gyno.1995.1262

    authors: Berchuck A,Anspach C,Evans AC,Soper JT,Rodriguez GC,Dodge R,Robboy S,Clarke-Pearson DL

    更新日期:1995-10-01 00:00:00

  • A ten year experience of cecal neovagina procedures for the restoration of sexual function on a gynecology oncology service.

    abstract:OBJECTIVE:We seek to describe the procedure, complications, and functional outcomes of utilizing the cecum and ascending colon for creation of a neovagina on a gynecologic oncology service. METHODS:A search of all the cases on the gynecologic oncology service over a ten year period yielded fourteen cases of cecal neov...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2014.04.058

    authors: Khulpateea BR,Silver DF

    更新日期:2014-07-01 00:00:00

  • A phase II clinical trial of pegylated liposomal doxorubicin and carboplatin plus bevacizumab in patients with platinum-sensitive recurrent ovarian, fallopian tube, or primary peritoneal cancer.

    abstract:OBJECTIVE:To assess the safety and efficacy of pegylated liposomal doxorubicin (PLD), carboplatin, plus bevacizumab in patients with ovarian, fallopian tube, or primary peritoneal cancer. METHODS:Patients with platinum-sensitive, recurrent disease received PLD 30 mg/m(2) and carboplatin area under the curve (AUC) 5 on...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.ygyno.2012.05.028

    authors: del Carmen MG,Micha J,Small L,Street DG,Londhe A,McGowan T

    更新日期:2012-09-01 00:00:00

  • MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer.

    abstract:OBJECTIVES:Most ovarian cancer patients are diagnosed at an advanced stage (67%) and prospects for significant improvement in survival reside in early diagnosis. While expression patterns of a recently identified biomarker family, microRNA, appear to be characteristic of tumor type and developmental origin, microRNA pr...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2008.04.033

    authors: Taylor DD,Gercel-Taylor C

    更新日期:2008-07-01 00:00:00

  • The immune response in pregnancy and in cancer is active and supportive of placental and tumor cell growth not their destruction.

    abstract::While many investigators have described the biochemical and physiological similarities between tumor cells and trophoblast cells, in this discourse we will compare primarily their leucocytes, which constitute a large portion of the tumor and its microenvironment as well as the placenta and its microenvironment. There ...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,评审

    doi:10.1016/j.ygyno.2017.04.019

    authors: Beaman KD,Dambaeva S,Katara GK,Kulshrestha A,Gilman-Sachs A

    更新日期:2017-06-01 00:00:00

  • Laparoscopy-assisted vaginal pelvic exenteration.

    abstract:OBJECTIVE:The aim of this study was to evaluate the feasibility, morbidity and survival outcome of laparoscopy-assisted vaginal pelvic exenteration. METHODS:Since 2000, we have performed 5 cases of en-bloc pelvic exenteration combining a vaginal or perineal approach and laparoscopic approach. All patients had received...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2005.09.027

    authors: Ferron G,Querleu D,Martel P,Letourneur B,Soulié M

    更新日期:2006-03-01 00:00:00

  • DNA aneuploidy is associated with increased mortality for stage I endometrial cancer.

    abstract:OBJECTIVE:The current study was undertaken to determine if DNA ploidy is a useful prognostic variable for predicting recurrence in stage I endometrial cancer. For cancer of the endometrium, survival following recurrence may depend on a number of factors, including the pattern of recurrence and the response to second li...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2004.08.031

    authors: Terada K,Mattson D,Goo D,Shimizu D

    更新日期:2004-12-01 00:00:00

  • Electronic patient-reported symptom monitoring in patients recovering from ambulatory minimally invasive gynecologic surgery: A prospective pilot study.

    abstract:OBJECTIVE:To evaluate the feasibility of an electronic symptom-tracking platform for patients recovering from ambulatory surgery. METHOD:We assessed user response to an electronic system designed to self-report symptoms. Endpoints included compliance, postoperative symptoms, patient satisfaction. An 8-item symptom inv...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2020.07.004

    authors: Zivanovic O,Chen LY,Vickers A,Straubhar A,Baser R,Veith M,Aiken N,Carter J,Curran K,Simon B,Mueller J,Jewell E,Chi DS,Sonoda Y,Abu-Rustum NR,Leitao MM Jr

    更新日期:2020-10-01 00:00:00

  • Oncocytoma of the ovary: light and electron microscopic study.

    abstract::An oncocytoma of the right ovary in a 22-year-old Japanese woman was examined by light and electron microscopy. The tumor was composed of oxyphilic cells with a granular cytoplasm. Electron microscopic studies revealed mitochondrial hyperplasia, a characteristic feature of the oncocyte . This may be the first report o...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/0090-8258(84)90013-1

    authors: Yoshida Y,Tenzaki T,Ishiguro T,Kawanami D,Ohshima M

    更新日期:1984-05-01 00:00:00

  • Prospective cohort study of metabolic syndrome and endometrial cancer survival.

    abstract:OBJECTIVE:Comorbidities are known to increase endometrial cancer risk, but the separate and combined impact of these risk factors on endometrial cancer survival remains unclear. This study aimed to determine the associations between metabolic syndrome and its components with disease-free survival, overall survival, end...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2020.06.488

    authors: Kokts-Porietis RL,McNeil J,Nelson G,Courneya KS,Cook LS,Friedenreich CM

    更新日期:2020-09-01 00:00:00

  • Intraperitoneal chemotherapy: analysis of complications with an implanted subcutaneous port and catheter system.

    abstract::To determine the morbidity associated with delivery of intraperitoneal chemotherapy via subcutaneous semipermanent infusion catheters, we analyzed the data on 227 patients treated from April 1985 through December 1989. A total of 249 catheters were inserted and used to administer chemotherapy in these patients. There ...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/0090-8258(91)90266-8

    authors: Davidson SA,Rubin SC,Markman M,Jones WB,Hakes TB,Reichman B,Almadrones L,Chapman D,Lewis JL Jr,Hoskins WJ

    更新日期:1991-05-01 00:00:00

  • Prospective evaluation of prognostic significance of the tumor-free distance from uterine serosa in surgically staged endometrial adenocarcinoma.

    abstract:OBJECTIVE:To determine if tumor-free distance (TFD) from the uterine serosa predicts surgicopathologic factors and outcome in surgically staged endometrial cancer, and to compare TFD with the traditional estimate of depth of myometrial invasion (DOI). METHODS:Patients who underwent complete surgical staging for primar...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2008.09.009

    authors: Schwab KV,O'Malley DM,Fowler JM,Copeland LJ,Cohn DE

    更新日期:2009-01-01 00:00:00

  • Clinical outcome of neoadjuvant chemotherapy for advanced ovarian cancer.

    abstract:OBJECTIVE:To evaluate clinical outcome in patients selected to receive neoadjuvant chemotherapy (NACT) compared to primary debulking surgery (PDS). METHODS:Retrospective study including all consecutive patients diagnosed and treated for advanced (stages III-IV) ovarian cancers between the years 2003-2015. RESULTS:263...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2016.12.017

    authors: Kessous R,Laskov I,Abitbol J,Bitharas J,Yasmeen A,Salvador S,Lau S,Gotlieb WH

    更新日期:2017-03-01 00:00:00

  • Traditional and nontraditional histopathologic predictors of recurrence in uterine endometrioid adenocarcinoma.

    abstract::Ninety-three consecutive operative cases of myometrial invasive endometrioid adenocarcinoma of the uterus without evidence of extrauterine spread at surgery were reviewed to determine whether any histopathologic features other than those traditionally reported might predict recurrence. Recurrence was associated with t...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1006/gyno.1994.1158

    authors: Lee KR,Vacek PM,Belinson JL

    更新日期:1994-07-01 00:00:00

  • Does adjuvant chemotherapy dose modification have an impact on the outcome of patients diagnosed with advanced stage ovarian cancer? An NRG Oncology/Gynecologic Oncology Group study.

    abstract:PURPOSE:To determine the relationship between chemotherapy dose modification (dose adjustment or treatment delay), overall survival (OS) and progression-free survival (PFS) for women with advanced-stage epithelial ovarian carcinoma (EOC) and primary peritoneal carcinoma (PPC) who receive carboplatin and paclitaxel. ME...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.ygyno.2018.07.021

    authors: Olawaiye AB,Java JJ,Krivak TC,Friedlander M,Mutch DG,Glaser G,Geller M,O'Malley DM,Wenham RM,Lee RB,Bodurka DC,Herzog TJ,Bookman MA

    更新日期:2018-10-01 00:00:00

  • Cyclooxygenase-2 in cervical neoplasia: a review.

    abstract:OBJECTIVE:Previous data demonstrate an association between cyclooxygenase activity and development of cervical cancer. This review investigates the role of cyclooxygenase-2 (COX-2) in the development of cervical cancer and potential therapeutic options targeting this pathway. METHODS:A literature search was conducted ...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,评审

    doi:10.1016/j.ygyno.2008.01.008

    authors: Young JL,Jazaeri AA,Darus CJ,Modesitt SC

    更新日期:2008-04-01 00:00:00

  • Is aspirin use associated with a decreased risk of ovarian cancer? A systematic review and meta-analysis of observational studies with dose-response analysis.

    abstract:OBJECTIVE:Currently available epidemiologic evidences concerning the chemopreventive effect of aspirin on ovarian cancer are inconsistent. Therefore, we aimed to further explore the association by synthesizing evidence from population-based studies. METHODS:We searched PubMed, EMBASE, Web of Science, and Scopus using ...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.ygyno.2016.04.543

    authors: Zhang D,Bai B,Xi Y,Wang T,Zhao Y

    更新日期:2016-08-01 00:00:00