Minimal change disease in a patient with ovarian papillary serous carcinoma.

Abstract:

BACKGROUND:Nephrotic syndrome (NS) is rarely associated with ovarian tumor. Only five cases of NS with pathologic diagnosis have been reported in patients with ovarian tumors. However, the association between minimal change disease (MCD) and ovarian tumor has not been previously reported. CASE:A 55-year-old woman presented with abdominal mass and edema. Radiologic studies revealed a 10 x 10 x 11 cm-sized mass and multiple enlarged lymph nodes, suggesting a malignant ovarian tumor. Urinalysis showed heavy proteinuria (4+) with decreased serum albumin and increased cholesterol levels, suggesting NS. She underwent operation and renal biopsy. Histopathology of the mass and the kidney revealed papillary serous carcinoma of the ovary and MCD, respectively. Oral prednisolone and adjuvant chemotherapy resulted in remission of NS. CONCLUSION:We herein report a case of MCD associated with ovarian carcinoma.

journal_name

Gynecol Oncol

journal_title

Gynecologic oncology

authors

Ryu DR,Yoo TH,Kim YT,Jeong HJ,Cho NH,Kang SW

doi

10.1016/j.ygyno.2004.02.022

subject

Has Abstract

pub_date

2004-05-01 00:00:00

pages

554-6

issue

2

eissn

0090-8258

issn

1095-6859

pii

S0090825804001337

journal_volume

93

pub_type

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