Vulvar epithelioid sarcoma in pregnancy.

abstract：:The existing means of detecting recurrent ovarian carcinoma are notoriously poor. Positron emission tomography (PET) is a form of computer-assisted imaging which produces images reflective of the biochemistry of the tissues rather than their physical characteristics. PET imaging with the positron emitting glucose anal...

journal_title：Gynecologic oncology

authors： Karlan BY,Hawkins R,Hoh C,Lee M,Tse N,Cane P,Glaspy J

更新日期：1993-11-01 00:00:00

abstract：OBJECTIVE:Endometrial cancer (EC) is a rare condition in young women. The objective of this study was to evaluate the risk of pelvic lymph node (LN) metastasis in young women with EC who are candidates for conservative management. METHODS:Using the SEER database, a population-based analysis was conducted to identify w...

journal_title：Gynecologic oncology

authors： Gonthier C,Douhnai D,Koskas M

更新日期：2020-04-01 00:00:00

abstract：OBJECTIVE:Comorbidities are known to increase endometrial cancer risk, but the separate and combined impact of these risk factors on endometrial cancer survival remains unclear. This study aimed to determine the associations between metabolic syndrome and its components with disease-free survival, overall survival, end...

journal_title：Gynecologic oncology

authors： Kokts-Porietis RL,McNeil J,Nelson G,Courneya KS,Cook LS,Friedenreich CM

更新日期：2020-09-01 00:00:00

abstract：:To test the association between cytotoxicity and in vitro cell cycle perturbations we systematically studied cell cycle perturbations after exposing human ovarian cancer cells to nine commonly used cytotoxic agents. Three principal patterns of cell cycle alterations were observed: a sequential S-G2/M block after expos...

journal_title：Gynecologic oncology

authors： Petru E,Sevin BU,Haas J,Ramos R,Perras J

更新日期：1995-07-01 00:00:00

abstract：:Three cases of papillary villoglandular carcinoma of the cervix are presented. Each patient was multiparous and presented with abnormal vaginal bleeding. The mean age at presentation was 35 years (range 28-42 years). All patients were staged as FIGO IB and underwent radical Wertheim hysterectomy and bilateral pelvic l...

journal_title：Gynecologic oncology

authors： Hopson L,Jones MA,Boyce CR,Tarraza HM Jr

更新日期：1990-11-01 00:00:00

abstract：:PI3K/AKT/mTOR pathway is a crucial mediator of tumor progression. As the PI3K/Akt pathway is heavily deregulated in breast cancer, the application of mTOR inhibitors in breast cancer patients seems warranted. This is the first systematic review according to PRISMA guidelines to synthesize all available data of mTOR in...

journal_title：Gynecologic oncology

authors： Zagouri F,Sergentanis TN,Chrysikos D,Filipits M,Bartsch R

更新日期：2012-12-01 00:00:00

abstract：:A 58-year-old postmenopausal woman with primary ovarian serous carcinoma presented with the syndrome of inappropriate antidiuresis (SIAD). Preoperative workup showed serum sodium level of 110 mEq/liter and antidiuretic hormone level of 3.3 pg/ml. The serum and urine osmolarity were 239 and 371, respectively. Antidiure...

journal_title：Gynecologic oncology

authors： Taskin M,Barker B,Calanog A,Jormark S

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND:Invasive vulvar carcinoma is reported to occur in 5 to 20% of patients with vulvar Paget's disease. We report a case in which a clinically inapparent invasive lesion was discovered on reexcision of microscopically persistent vulvar Paget's disease. CASE:A 58-year-old woman presented with a diagnosis of vulv...

journal_title：Gynecologic oncology

authors： Awtrey CS,Marshall DS,Soslow RA,Chi DS

更新日期：2003-03-01 00:00:00

abstract：:An epidemiologic study of multiple primary malignant neoplasms in endometrial cancer patients in Israel is presented. During the 7-year period of the study, 104 patients (10.3%) out of 1007 patients diagnosed as having endometrial cancer had another primary cancer. There was a significant difference in the incidence o...

journal_title：Gynecologic oncology

authors： Schwartz Z,Ohel G,Birkenfeld A,Anteby SO,Schenker JG

更新日期：1985-09-01 00:00:00

abstract：OBJECTIVE:To determine if DNA ploidy, hormone receptors, vascular space invasion (VSI), perivascular lymphocytes (PVL), and the oncogenes HER-2/neu, p53, and bcl-2 are independent prognostic indicators for lymph node metastasis and cancer recurrence in clinical stage I endometrial carcinoma. METHODS:Among 349 patients...

journal_title：Gynecologic oncology

authors： Bell JG,Minnick A,Reid GC,Judis J,Brownell M

更新日期：1997-09-01 00:00:00

abstract：:The purpose of this study was to evaluate the serum tumor markers CYFRA 21-1 and squamous-cell carcinoma antigen (SCC) in the follow-up of squamous-cell cervical cancer patients. One hundred-ninety-three serum samples, which were collected pretherapeutically and during follow-up of 30 patients suffering from squamous-...

journal_title：Gynecologic oncology

authors： Kainz C,Sliutz G,Mustafa G,Bieglmayr C,Koelbl H,Reinthaller A,Gitsch G

更新日期：1995-03-01 00:00:00

abstract：BACKGROUND:Luteinized thecoma of the ovary associated with sclerosing peritonitis is a rare tumor that has no standard definitive treatment regimen. CASE:A 25 year-old patient diagnosed with luteinized thecoma and sclerosing peritonitis in the omentum. The patient received high dose corticosteroids (IV Hydrocortisone ...

journal_title：Gynecologic oncology

authors： Schonman R,Klein Z,Edelstein E,Czernobilsky B,Fishman A

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVE:The purpose was to examine the outcomes of patients with advanced ovarian cancer treated with neoadjuvant chemotherapy, with a special emphasis on the patients' quality of life (QOL). METHODS:Seventeen patients with advanced ovarian cancer were treated with neoadjuvant chemotherapy based on the extent of dis...

journal_title：Gynecologic oncology

authors： Chan YM,Ng TY,Ngan HY,Wong LC

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to determine whether thromboembolic events (TE) in cervical cancer patients are associated with survival by comparing the survival of patients with and without thromboembolic events over a seven year period. METHODS:Utilizing a retrospective chart review we identified patients ...

journal_title：Gynecologic oncology

authors： Jacobson G,Lammli J,Zamba G,Hua L,Goodheart MJ

更新日期：2009-05-01 00:00:00

abstract：:Lynch syndrome II was diagnosed when two sisters manifested early-onset synchronous carcinomas of the ovary and endometrium and a third sister was found to have Duke's A carcinoma of the cecum. A detailed cancer family history indicated paternal transmission of the deleterious genotype. The pattern of carcinoma of the...

journal_title：Gynecologic oncology

authors： Lynch HT,Cavalieri RJ,Lynch JF,Casey MJ

更新日期：1992-02-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to profile cervical squamous cell carcinoma in elderly patients undergoing radiation therapy and to study the treatment outcome and side effects of therapy. MATERIALS AND METHODS:A retrospective analysis was carried out from the records of 380 patients with squamous cell carcino...

journal_title：Gynecologic oncology

authors： Sakurai H,Mitsuhashi N,Takahashi M,Yamakawa M,Akimoto T,Hayakawa K,Niibe H

更新日期：2000-04-01 00:00:00

abstract：OBJECTIVE:BRCA-associated and sporadic ovarian cancers have different pathologic and clinical features. Our goal was to determine if BRCA mutation status is an independent predictor of residual tumor volume following primary surgical cytoreduction. METHODS:We conducted a retrospective analysis of patients with FIGO st...

journal_title：Gynecologic oncology

authors： Hyman DM,Long KC,Tanner EJ,Grisham RN,Arnold AG,Bhatia J,Phillips MF,Spriggs DR,Soslow RA,Kauff ND,Levine DA

更新日期：2012-08-01 00:00:00

abstract：:Two patients with resistant gestational choriocarcinoma were treated w with Taxol after extensive prior chemotherapy including EMACO and platinum-based salvage chemotherapy. Both patients showed significant responses to Taxol. One patient relapsed in the brain and liver after treatment and died. Taxol was combined wit...

journal_title：Gynecologic oncology

authors： Jones WB,Schneider J,Shapiro F,Lewis JL Jr

更新日期：1996-04-01 00:00:00

abstract：OBJECTIVE:Cyclin-dependent kinase 7 (CDK7) engages tumor growth by acting as a direct link between the regulation of transcription and the cell cycle. Here, we investigated the clinical significance of CDK7 expression and its potential as a therapeutic target in epithelial ovarian cancer (EOC). METHODS:CDK7 expression...

journal_title：Gynecologic oncology

authors： Kim J,Cho YJ,Ryu JY,Hwang I,Han HD,Ahn HJ,Kim WY,Cho H,Chung JY,Hewitt SM,Kim JH,Kim BG,Bae DS,Choi CH,Lee JW

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:In the present study we detected 72-kDa metalloproteinase expression in our series of early stage cervical carcinomas and analyzed the relationship between 72-kDa metalloproteinase staining and risk of nodal involvement with the goal of identifying a parameter useful in predicting the metastatic potential of ...

journal_title：Gynecologic oncology

authors： Garzetti GG,Ciavattini A,Lucarini G,Goteri G,Romanini C,Biagini G

更新日期：1996-02-01 00:00:00

abstract：OBJECTIVE:Human papillomavirus (HPV) genotype distribution in invasive cervical cancer (ICC) is critical to guide the introduction and to assess the impact of HPV prophylactic vaccines. This study aims to provide specific information for Spain. METHODS:1043 histological confirmed ICC cases diagnosed from 1940 to 2007 ...

journal_title：Gynecologic oncology

authors： Alemany L,Pérez C,Tous S,Llombart-Bosch A,Lloveras B,Lerma E,Guarch R,Andújar M,Pelayo A,Alejo M,Ordi J,Klaustermeier J,Velasco J,Guimerà N,Clavero O,Castellsagué X,Quint W,Muñoz N,Bosch FX,de Sanjosé S,Spanish st

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to analyze our experience with colorectal function preservation at the time of pelvic exenteration. METHODS:Between January 1980 and December 2001, 201 pelvic exenterations for gynecologic malignancies were performed in our hospital. Ninety-eight were supralevator exenteration...

journal_title：Gynecologic oncology

authors： Moutardier V,Houvenaeghel G,Lelong B,Mokart D,Delpero JR

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVE:Aberrant expression of HER2/neu and PIK3CA gene products secondary to amplification/mutations are common in high-grade-serous-endometrial (USC) and ovarian-cancers (HGSOC). Because scant information is currently available in the literature on the potential negative effect of PIK3CA mutations on the activity o...

journal_title：Gynecologic oncology

authors： Bonazzoli E,Cocco E,Lopez S,Bellone S,Zammataro L,Bianchi A,Manzano A,Yadav G,Manara P,Perrone E,Haines K,Espinal M,Dugan K,Menderes G,Altwerger G,Han C,Zeybek B,Litkouhi B,Ratner E,Silasi DA,Huang GS,Azodi M,

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVE:Describing the pattern of and reasons for post-operative tumor residuals in patients with advanced epithelial ovarian cancer (AOC) operated in a specialized gynecologic cancer center following a strategy of maximum upfront debulking followed by systemic chemotherapy. METHODS:All consecutive AOC-patients trea...

journal_title：Gynecologic oncology

authors： Heitz F,Harter P,Alesina PF,Walz MK,Lorenz D,Groeben H,Heikaus S,Fisseler-Eckhoff A,Schneider S,Ataseven B,Kurzeder C,Prader S,Beutel B,Traut A,du Bois A

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVES:High grade undifferentiated uterine sarcomas (HGUS) are rare, aggressive malignancies. Data regarding management are limited. We aimed to describe disease stage, response to treatment, and survival outcomes among patients with HGUS at our institution. METHODS:We identified all patients with HGUS who receive...

journal_title：Gynecologic oncology

authors： Tanner EJ,Garg K,Leitao MM Jr,Soslow RA,Hensley ML

更新日期：2012-10-01 00:00:00

abstract：INTRODUCTION:Placental site trophoblastic tumor (PSTT) is a rare variant of gestational trophoblastic disease that has been re-described during the 1970s. MATERIALS AND METHODS:The patients' age at presentation, presenting symptoms, description of last pregnancy, treatment, and outcome were analyzed in five patients d...

journal_title：Gynecologic oncology

authors： Machtinger R,Gotlieb WH,Korach J,Fridman E,Apter S,Goldenberg M,Ben-Baruch G

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:We demonstrate the feasibility of implementing a referral and management system for cryotherapy-ineligible women in a "screen-and-treat" cervical cancer prevention program targeting HIV-infected women in Zambia. METHODS:We established criteria for patient referral, developed a training program for loop elect...

journal_title：Gynecologic oncology

authors： Pfaendler KS,Mwanahamuntu MH,Sahasrabuddhe VV,Mudenda V,Stringer JS,Parham GP

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:Ras gene mutations have been identified in squamous cell carcinomas of the cervix and are associated with advanced-stage tumors. The current study was designed to determine the prevalence of c-Ki-ras mutations in invasive endocervical adenocarcinomas and associations between mutations, HPV status, and known p...

journal_title：Gynecologic oncology

authors： Koulos JP,Wright TC,Mitchell MF,Silva E,Atkinson EN,Richart RM

更新日期：1993-03-01 00:00:00

abstract：:Ovarian, endometrial and cervical cancers are the most prevalent gynecologic cancers in the United States and account for significant mortality. Translational research into these cancers has highlighted the distinctive molecular and genomic profiles of these cancers finding that, even within a disease site, the landsc...

journal_title：Gynecologic oncology

authors： Bregar AJ,Growdon WB

更新日期：2016-02-01 00:00:00

abstract：OBJECTIVE:The long-term survival of patients with epithelial ovarian cancer is limited by the emergence of tumor cells that are resistant to chemotherapy. We hypothesized that expression of Bcl-x(L), a homologue of Bcl-2 that confers protection from chemotherapy-induced apoptosis, may be predictive of patients' clinica...

journal_title：Gynecologic oncology

authors： Williams J,Lucas PC,Griffith KA,Choi M,Fogoros S,Hu YY,Liu JR

更新日期：2005-02-01 00:00:00