A case of successful pregnancy after treatment of invasive cervical cancer with systemic chemotherapy and conization.

Abstract:

BACKGROUND:The standard therapy for invasive uterine cervical cancer causes loss of the woman's fertility. We report a successful pregnancy in a patient who desired fertility-sparing management of invasive cervical cancer and was treated with systemic chemotherapy and conization. CASE:A 28-year-old nulliparous woman was diagnosed with a large 30-mm-diameter stage IB1 squamous cell carcinoma of the uterine cervix. The patient received 4 courses of systemic chemotherapy with consecutive low-dose BOMP (cisplatin, bleomycin, vincristine and mitomycin C), which produced complete pathological response assessed by examination of specimens from conization. Two years later, the patient became pregnant, resulting in the birth of a healthy infant. CONCLUSION:This procedure is one method of conservative management to preserve fertility in invasive cervical cancer.

journal_name

Gynecol Oncol

journal_title

Gynecologic oncology

authors

Kobayashi Y,Akiyama F,Hasumi K

doi

10.1016/j.ygyno.2005.08.018

subject

Has Abstract

pub_date

2006-01-01 00:00:00

pages

213-5

issue

1

eissn

0090-8258

issn

1095-6859

pii

S0090-8258(05)00717-1

journal_volume

100

pub_type

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