Standing on the shoulders of giants: Mentorship advice from leaders in the field.

abstract：:Two cases with squamous cell carcinoma of the cervix stage IIB with primary tumor mass about 2 X 2 X 2 cm were treated with primary chemotherapy of cis-platinum, 20 micrograms/m2 body surface intravenously daily for 5 consecutive days. Papanicolaou smear turned negative after two courses of chemotherapy in both cases....

journal_title：Gynecologic oncology

authors： Kim DS,Moon H,Kang KJ

更新日期：1985-09-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to assess the safety, efficacy and impact on survival of low anterior resection and primary anastomosis at the time of en bloc resection for primary and recurrent epithelial ovarian carcinoma. METHODS:We performed a retrospective review of 46 primary and 14 recurrent epithelial ova...

journal_title：Gynecologic oncology

authors： Park JY,Seo SS,Kang S,Lee KB,Lim SY,Choi HS,Park SY

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVES:The objectives of this multicenter phase II study were to evaluate the effects of gemcitabine-paclitaxel-cisplatin combination chemotherapy on response rate, survival, and toxicity in patients with advanced epithelial ovarian cancer (AEOC). METHODS:Chemonaive AEOC patients with bidimensionally measurable di...

journal_title：Gynecologic oncology

authors： Gupta SK,John S,Naik R,Arora R,Selvamani B,Fuloria J,Ganesh N,Awasthy BS

更新日期：2005-07-01 00:00:00

abstract：:We examined the efficacy of CA125 and urinary gonadotropin fragment (UGF) measurements for differentiating benign from malignant pelvic masses. CA125, at a cutoff of greater than or equal to 35 U/ml, detected 82% (n = 71) of ovarian malignancies, but also falsely detected 14% of (n = 332) patients with benign pelvic m...

journal_title：Gynecologic oncology

authors： Cole LA,Nam JH,Chambers JT,Schwartz PE

更新日期：1990-03-01 00:00:00

abstract：:The Swedish Tumor Registries are population based. Three hundred eighty-four patients with epithelial ovarian cancer registered in the Tumor Registry of the Southeast Health Care Region during the years 1984 to 1987 were reviewed; 332 patients were eligible for survival analysis. The protocol treatment during this per...

journal_title：Gynecologic oncology

authors： Högberg T,Carstensen J,Simonsen E

更新日期：1993-01-01 00:00:00

abstract：INTRODUCTION:We describe a case of conservatively treated endometrial endometrioid (EE) adenocarcinoma which showed an aggressive clinical outcome after pregnancy. CASE:A 30-year-old woman with a well differentiated EE adenocarcinoma decided to attempt a conservative approach and underwent progestin treatment with sub...

journal_title：Gynecologic oncology

authors： Ferrandina G,Zannoni GF,Gallotta V,Foti E,Mancuso S,Scambia G

更新日期：2005-10-01 00:00:00

abstract：:A 75-year-old Japanese woman, who had an enlarged uterus and two nodules on the anterior vaginal wall, underwent wide excision of the anterior vaginal wall, bilateral inguinal lymphadenectomy, modified radical hysterectomy, and pelvic lymph node dissection. Her serum level of 5-S-cysteinyldopa (5-S-CD) was elevated, b...

journal_title：Gynecologic oncology

authors： Suenaga Y,Katabuchi H,Okamura H,Kageshita T,Ono T

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Post-irradiation breast sarcoma is a rare and highly aggressive tumor, associated with poor prognosis. However, the mean latent periods reported for postradiation sarcomas after treatment of breast cancer ranges from 5 to 10 years. CASE:We present a rare case of fibrosarcoma of the axilla, diagnosed 23 mont...

journal_title：Gynecologic oncology

authors： Plotti F,Di Donato V,Zullo MA,Angioli R,Panici PB

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVE:Self-collected HPV testing could substantially reduce disparities in cervical cancer screening, with slightly lower sensitivity compared to physician-collected specimens cross-sectionally. We aimed to evaluate the comprehensive long-term performance of self-collected HPV testing prospectively. METHODS:In 199...

journal_title：Gynecologic oncology

authors： Zhang L,Xu XQ,Hu SY,Chen F,Zhang X,Pan QJ,Zhang WH,Feng RM,Dong L,Zhang Q,Ma JF,Sauvaget C,Zhao FH,Qiao YL,Sankaranarayanan R

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVES:Laminin-5 is an attachment protein for epithelial cells. Several studies of a variety of cancers have reported increased expression of laminin-5 in carcinoma in situ and invasive cancer. This study was designed to investigate the correlation between the grade of cervical intraepithelial neoplasia and the imm...

journal_title：Gynecologic oncology

authors： Kohlberger P,Beneder Ch,Horvat R,Leodolter S,Breitenecker G

更新日期：2003-06-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to retrospectively evaluate the technique, feasibility and oncological safety of laparoscopic radical hysterectomy with vaginectomy and reconstruction of vagina in patients with stage I primary vaginal carcinomas. METHODS:Between February 2003 and July 2004, four patients, that...

journal_title：Gynecologic oncology

authors： Ling B,Gao Z,Sun M,Sun F,Zhang A,Zhao W,Hu W

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the association between lymphopenia and survival in women with cervical cancer treated with primary chemoradiation. METHODS:A single institution, retrospective analysis of patients with stage IB2-IVA cervical cancer who received upfront chemoradiation from 1998 to 2013 was performed. Complete blo...

journal_title：Gynecologic oncology

authors： Wu ES,Oduyebo T,Cobb LP,Cholakian D,Kong X,Fader AN,Levinson KL,Tanner EJ 3rd,Stone RL,Piotrowski A,Grossman S,Roche KL

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:An epigenetic approach to explaining endometrial carcinogenesis necessitates good understanding of Ras association domain family 1 isoform A (RASSF1A) promoter methylation data from primary studies. AIMS:Differential magnitude of reported associations between RASSF1A promoter methylation and endometrial can...

journal_title：Gynecologic oncology

authors： Pabalan N,Kunjantarachot A,Ruangpratheep C,Jarjanazi H,Christofolini DM,Barbosa CP,Bianco B

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVES:To investigate access to surgical care for endometrial cancer in Arizona. METHODS:The Arizona HealthQuery (AZHQ) data warehouse with claims information on over 7 million patients in Arizona was searched using the International Classification of Disease (ICD-9) codes and Current Procedural Terminology (CPT) ...

journal_title：Gynecologic oncology

authors： Benjamin I,Dalton H,Qiu Y,Cayco L,Johnson WG,Balducci J

更新日期：2011-04-01 00:00:00

abstract：:The thoroughness of cytoreductive surgery is the largest contributor to survival for patients with advanced ovarian and primary peritoneal carcinoma. For many years the surgery undertaken by Gynaecologic Oncologists has been tailored to match their surgical training. Future surgical training of Gynaecologic Oncologist...

journal_title：Gynecologic oncology

authors： Crandon AJ,Obermair A

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVES:Molecular markers associated with tumor progression in uterine carcinoma are poorly defined. In this study, we determine whether upregulation of LAMC1, a gene encoding extracellular matrix protein, laminin γ1, is associated with various uterine carcinoma subtypes and stages of tumor progression. METHODS:An ...

journal_title：Gynecologic oncology

authors： Kashima H,Wu RC,Wang Y,Sinno AK,Miyamoto T,Shiozawa T,Wang TL,Fader AN,Shih IeM

更新日期：2015-11-01 00:00:00

abstract：:Immunotherapy (IO) is an important new pillar in the treatment of solid tumors, and the integration of IO agents with chemotherapy, targeted therapy, surgery and radiation has yet to be defined. As preclinical and clinical studies have described synergistic activity with the combination of radiation and immunotherapy,...

journal_title：Gynecologic oncology

authors： Lee L,Matulonis U

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVE:Endometrioid endometrial carcinoma is caused by a combination of mutational events and hormonal factors. We used large-scale messenger RNA expression analysis to discover genes that distinguish neoplastic transformation and examine the patterns of tumor expression of those genes which are normally regulated d...

journal_title：Gynecologic oncology

authors： Mutter GL,Baak JP,Fitzgerald JT,Gray R,Neuberg D,Kust GA,Gentleman R,Gullans SR,Wei LJ,Wilcox M

更新日期：2001-11-01 00:00:00

abstract：PURPOSE:To examine the relative efficacy of cisplatin-based intraperitoneal (IP) therapy versus carboplatin-based IP therapy as salvage treatment of small-volume residual ovarian cancer. PATIENTS AND METHODS:We retrospectively examined the surgically defined response rates of patients with ovarian cancer treated at th...

journal_title：Gynecologic oncology

authors： Markman M,Reichman B,Hakes T,Rubin S,Lewis JL Jr,Jones W,Barakat R,Curtin J,Almadrones L,Hoskins W

更新日期：1993-07-01 00:00:00

abstract：:Twenty cases of gestational trophoblastic disease in women aged 50 or more are reported. The lesions were 7 hydatidiform mole (35%), 8 invasive mole (40%), and 5 choriocarcinoma (25%). The most common presenting symptom was abnormal vaginal bleeding. Three choriocarcinoma patients were postmenopausal and all of them h...

journal_title：Gynecologic oncology

authors： Tsukamoto N,Iwasaka T,Kashimura Y,Uchino H,Kashimura M,Matsuyama T

更新日期：1985-01-01 00:00:00

abstract：:Absorbable synthetic mesh (910-polyglactin) was used to create an intestinal sling in six patients undergoing surgical staging of pelvic malignancies prior to radiation therapy. All patients had effective compartmentalization of small intestine out of the pelvis which persisted throughout the duration of radiation the...

journal_title：Gynecologic oncology

authors： Soper JT,Clarke-Pearson DL,Creasman WT

更新日期：1988-03-01 00:00:00

abstract：BACKGROUND:Metformin has been associated with reduced cancer risk. The mechanisms underlying this cancer protective effect remain unknown. METHODS:"Window of opportunity" study of metformin in women with operable endometrial cancer (EC). Eleven newly diagnosed, untreated, non-diabetic patients with EC received metform...

journal_title：Gynecologic oncology

authors： Laskov I,Drudi L,Beauchamp MC,Yasmeen A,Ferenczy A,Pollak M,Gotlieb WH

更新日期：2014-09-01 00:00:00

abstract：PURPOSE:Intraperitoneal (IP) therapy improves survival compared to intravenous (IV) treatment for women with newly diagnosed, optimally cytoreduced, ovarian cancer. However, the role of IP therapy in recurrent disease is unknown. Preclinical data demonstrated IP administration of the proteasome inhibitor, bortezomib pr...

journal_title：Gynecologic oncology

authors： Jandial DA,Brady WE,Howell SB,Lankes HA,Schilder RJ,Beumer JH,Christner SM,Strychor S,Powell MA,Hagemann AR,Moore KN,Walker JL,DiSilvestro PA,Duska LR,Fracasso PM,Dizon DS

更新日期：2017-05-01 00:00:00

abstract：:Ovarian cancer is the leading cause of gynecologic cancer deaths in the U.S. The concept of intraperitoneal drug delivery for therapy of intraperitoneal cancers, such as ovarian cancer, arose in the 1960s. The field of intraperitoneal cisplatin therapy for ovarian cancer was initiated in the late 1970s and early 1980s...

journal_title：Gynecologic oncology

authors： Alberts DS,Markman M,Muggia F,Ozols RF,Eldermire E,Bookman MA,Chen T,Curtin J,Hess LM,Liebes L,Young RC,Trimble E

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the optimal cytoreduction (OPT) rate, National Comprehensive Cancer Network (NCCN) treatment guideline compliance rate and patient outcomes for advanced stage epithelial ovarian cancer (EOC) patients at our low volume institution. METHODS:Following IRB approval, records of patients with Stage III...

journal_title：Gynecologic oncology

authors： Phippen NT,Barnett JC,Lowery WJ,Miller CR,Leath CA 3rd

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:A 10-point "Surgical Apgar Score" (SAS) for predicting postoperative complications after general and vascular operations has recently been developed and validated. We sought to estimate the ability of this metric to predict major postoperative complications in women undergoing ovarian cancer cytoreductive pro...

journal_title：Gynecologic oncology

authors： Zighelboim I,Kizer N,Taylor NP,Case AS,Gao F,Thaker PH,Rader JS,Massad LS,Mutch DG,Powell MA

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:The objective of this study is to compare survival of Asian (AS), American Indian/Alaskan Native (AI/AN) and non-Hispanic white (NHW) women with endometrial adenocarcinoma (EC). METHODS:Patients with EC were identified from the Surveillance, Epidemiology, and End Results program from 1988 to 2009. Kaplan-Mei...

journal_title：Gynecologic oncology

authors： Mahdi H,Schlick CJ,Kowk LL,Moslemi-Kebria M,Michener C

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVES:A phase II trial was conducted to evaluate the anti-tumor activity and adverse effects of thalidomide in persistent or recurrent endometrial cancer refractory to cytotoxic chemotherapy and to correlate angiogenesis biomarker expression with clinical outcome. METHODS:Consenting patients were treated until pr...

journal_title：Gynecologic oncology

authors： McMeekin DS,Sill MW,Benbrook D,Darcy KM,Stearns-Kurosawa DJ,Eaton L,Yamada SD,Gynecologic Oncology Group.

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVE:Brachytherapy plays a major role in the treatment of patients with carcinoma of the cervix. However, routine intracavitary brachytherapy may not be feasible or adequate to treat locally advanced disease. The purpose of this prospective study was to assess treatment outcome for patients with locally advanced g...

journal_title：Gynecologic oncology

authors： Agrawal PP,Singhal SS,Neema JP,Suryanarayan UK,Vyas RK,Rathi AK,Bahadur AK

更新日期：2005-10-01 00:00:00

abstract：:The clinical and pathologic features of a vulvar neuroendocrine (Merkel cell) neoplasm are presented. Cytologic studies of material obtained from needle aspiration suggested that the tumor was a small cell neoplasm possibly of neuroendocrine derivation. The light-microscopic findings of sheets of small, uniform cells ...

journal_title：Gynecologic oncology

authors： Copeland LJ,Cleary K,Sneige N,Edwards CL

更新日期：1985-11-01 00:00:00