当前位置： SCI文献检索 > GYNECOLOGIC ONCOLOGY期刊下所有文献 > Loop electrocautery excisional procedure: therapeutic effectiveness as an ablation and a conization equivalent.

Loop electrocautery excisional procedure: therapeutic effectiveness as an ablation and a conization equivalent.

Abstract：

:This study was designed to compare the effectiveness of loop excision procedures as ablation and conization equivalents, and their use in recurrent cervical high-grade dysplasia patients. We retrospectively reviewed patients undergoing loop procedures between January 1992 and April 1994. Conization equivalents were defined as procedures performed for unsatisfactory colposcopy, positive endocervical curettage, discordant cytology and histology, and cytology suggestive of invasion. Effectiveness in high-grade recurrent lesions was evaluated separately. Therapeutic failure was defined as any recurrence of high-grade dysplasia. One hundred sixty-two patients underwent loop procedures, of which 123 (75.9%) had follow-up examinations and are included. Mean follow-up was 17.9 months. Seventy-six patients (61.8%) had the loop procedure performed as an ablation equivalent, 29 (23.6%) as a conization equivalent, and 18 (14.6%) for recurrent disease. Overall effectiveness was 82.1 % and for ablation and conization equivalent procedures was 82.9 and 82.8%, respectively. There was no significant difference between effectiveness when performed for initial therapy (82.9%) and for recurrent disease (72.2%) (P = 0.46). In conclusion, loop excision procedures are effective as ablation and conization equivalents and as treatment for recurrent high-grade dysplasia.

journal_name

Gynecol Oncol

journal_title

Gynecologic oncology

authors

Gold M,Dunton CJ,Murray J,Macones G,Hanau C,Carlson JA Jr

doi

10.1006/gyno.1996.0132

subject

Has Abstract

pub_date

1996-05-01 00:00:00

pages

241-4

issue

2

eissn

0090-8258

issn

1095-6859

pii

S0090825896901328

journal_volume

61

pub_type

杂志文章

相关文献

GYNECOLOGIC ONCOLOGY文献大全
  • Presence of oncogenic HPV DNAs in cervical carcinoma tissues and pelvic lymph nodes associating with proliferating cell nuclear antigen expression.

    abstract：:The presence of oncogenic HPV DNAs (HPV-16/18) in cervical carcinomas and their normal and metastatic pelvic lymph nodes and the expression patterns of proliferating cell nuclear antigen (PCNA) in cervical carcinomas were retrospectively studied to elucidate the possible roles of them in malignant transformation and p...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1006/gyno.1996.0066

    authors： Park JS,Rhyu KS,Kim CJ,Kim HS,Han KT,Ahn HK,Kim SJ,Namkoong SE

    更新日期：1996-03-01 00:00:00

  • The increase of mitochondrial DNA content in endometrial adenocarcinoma cells: a quantitative study using laser-captured microdissected tissues.

    abstract：OBJECTIVE:Microsatellite instability (MSI) is a frequent genetic event in the D-loop region (which controls mitochondrial DNA (mtDNA) replication) of mitochondrial genome of endometrial cancer. We therefore investigated the relationship between mtMSI and mtDNA content in endometrial cancer. METHODS:Tumor tissues from ...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2005.04.015

    authors： Wang Y,Liu VW,Xue WC,Tsang PC,Cheung AN,Ngan HY

    更新日期：2005-07-01 00:00:00

  • Costs of treatment and outcomes associated with second-line therapy and greater for relapsed ovarian cancer.

    abstract：OBJECTIVES:Most women with epithelial ovarian cancer (EOC) will develop disease progression or recurrence with resistance to platinum therapy. We report overall costs and treatment outcomes associated with topotecan or gemcitabine administration in platinum- and paclitaxel-resistant EOC patients. METHODS:Patients who ...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2004.01.014

    authors： Prasad M,Ben-Porat L,Hoppe B,Aghajanian C,Sabbatini P,Chi DS,Hensley ML

    更新日期：2004-04-01 00:00:00

  • A retrospective study to evaluate single agent methotrexate treatment in low risk gestational choriocarcinoma in the United Kingdom.

    abstract：OBJECTIVE:To determine whether single agent chemotherapy with intramuscular methotrexate 50mg administered on days 1, 3, 5, and 7 and oral folinic acid 15mg administered on days 2, 4, 6, and 8 in 2 weekly cycles (IM MTX/FA) is an effective treatment regimen for patients with low risk gestational choriocarcinoma. METHO...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.ygyno.2014.12.024

    authors： Taylor F,Short D,Winter MC,Tidy J,Savage PM,Sarwar N,Hancock BW,Seckl MJ,Coleman RE

    更新日期：2015-02-01 00:00:00

  • Anti-tumor activity of an anti-DR5 monoclonal antibody, TRA-8, in combination with taxane/platinum-based chemotherapy in an ovarian cancer model.

    abstract：OBJECTIVE:Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) mediates apoptosis via binding to death receptors and enhances the anti-tumor effect of conventional cancer therapies. We evaluated the efficacy of TRA-8, an agonistic antibody to DR5, combined with docetaxel and carboplatin in vitro in an intrap...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2010.11.046

    authors： Bevis KS,McNally LR,Sellers JC,Della Manna D,Londoño Joshi A,Amm H,Straughn JM Jr,Buchsbaum DJ

    更新日期：2011-04-01 00:00:00

  • Closed-suction drainage versus no drainage following radical abdominal hysterectomy with pelvic lymphadenectomy for stage IB cervical cancer.

    abstract：:Over a 7-year period from 1987 to 1994, 120 patients consecutive patients with FIGO stage IB invasive cervical cancer who underwent type 3 radical abdominal hysterectomy and bilateral pelvic lymphadenectomy had either Jackson-Pratt closed-suction drainage (Group 1, patients 1-60) or no drainage (Group 2, patients 61-1...

    journal_title：Gynecologic oncology

    pub_type： 临床试验,杂志文章

    doi：10.1006/gyno.1995.1131

    authors： Patsner B

    更新日期：1995-05-01 00:00:00

  • Efficacy of pegylated liposomal doxorubicin (PLD) plus carboplatin in ovarian cancer patients who recur within six to twelve months: a phase II study.

    abstract：OBJECTIVES:Pegylated liposomal doxorubicin is one of the preferred alternatives for ovarian cancer patients with early relapse (<6 months) and taxane/carboplatin for late relapse (>12 months), but the optimal therapy for the partially platinum-sensitive (6-12 months) population has not been defined. This single-arm pha...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.ygyno.2009.04.037

    authors： Power P,Stuart G,Oza A,Provencher D,Bentley JR,Miller WH Jr,Pouliot JF

    更新日期：2009-09-01 00:00:00

  • Continuous epidural infusion in gynecologic oncology patients undergoing exploratory laparotomy: The new standard for decreased postoperative pain and opioid use.

    abstract：OBJECTIVE:To compare the incidence of postoperative complications and opioid pain medication usage in gynecologic oncology patients who did and did not receive an epidural prior to undergoing exploratory laparotomy. METHODS:Retrospective cohort study of all patients undergoing exploratory laparotomy with the gynecolog...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2019.02.017

    authors： Huepenbecker SP,Cusworth SE,Kuroki LM,Lu P,Samen CDK,Woolfolk C,Deterding R,Wan L,Helsten DL,Bottros M,Mutch DG,Powell MA,Massad LS,Thaker PH

    更新日期：2019-05-01 00:00:00

  • Extra-peritoneal laparoscopic para-aortic lymphadenectomy--a prospective cohort study of 293 patients with endometrial cancer.

    abstract：OBJECTIVE:To determine if extra-peritoneal laparoscopic para-aortic (PA) lymphadenectomy allows a reliable assessment of PA nodes in patients with endometrial cancer (EC). METHODS:In October of 2005, a single surgeon began performing extra-peritoneal laparoscopic PA lymphadenectomy for patients with EC. A prospective ...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2008.08.021

    authors： Dowdy SC,Aletti G,Cliby WA,Podratz KC,Mariani A

    更新日期：2008-12-01 00:00:00

  • Topotecan combined with carboplatin in recurrent epithelial ovarian cancer: results of a single-institutional phase II study.

    abstract：OBJECTIVE:The aim of this trial was to investigate the efficacy and toxicity of a relative high-dose of topotecan combined with carboplatin in recurrent or persistent epithelial ovarian cancer (EOC). METHODS:Patients participating in this phase II trial received topotecan at a dose of 1.0 mg/m(2)/day intravenously (IV...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2009.04.016

    authors： Kang H,Kim TJ,Lee YY,Choi CH,Lee JW,Bae DS,Kim BG

    更新日期：2009-08-01 00:00:00

  • Stage I uterine carcinosarcoma: Matched cohort analyses for lymphadenectomy, chemotherapy, and brachytherapy.

    abstract：OBJECTIVE:To determine if lymphadenectomy, chemotherapy and radiotherapy are associated with survival benefit among women with stage I uterine carcinosarcoma. METHODS:Women with stage I uterine carcinosarcoma (n=5614) were identified from the 1998-2013 National Cancer Data Base. Kaplan-Meier survival estimates and Cox...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2017.01.010

    authors： Seagle BL,Kanis M,Kocherginsky M,Strauss JB,Shahabi S

    更新日期：2017-04-01 00:00:00

  • The prevalence of HPV16DNA in normal and pathological cervical scrapes using the polymerase chain reaction.

    abstract：:Human papillomavirus (HPV) has been implicated in the development of cervical cancer. Newly developed molecular techniques have facilitated HPV identification and typing of cervical lesions. Several studies have suggested a strong correlation between HPV16 and intraepithelial cervical neoplasia. However, there is no a...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/0090-8258(92)90191-k

    authors： Pasetto N,Sesti F,De Santis L,Piccione E,Novelli G,Dallapiccola B

    更新日期：1992-07-01 00:00:00

  • Detection of endometrial cancer cells in the fallopian tube lumen is associated with adverse prognostic factors and reduced survival.

    abstract：OBJECTIVE:Stage is a critical determinant of prognosis and treatment for endometrial cancer (EC) patients. Women who have had a tubal ligation for sterilization have improved EC survival, secondary to lower stage at presentation, suggesting that transtubal spread may represent an important route of metastasis. We evalu...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2018.05.005

    authors： Felix AS,Sinnott JA,Vetter MH,Rhoades J,Cohn DE,Backes FJ,Sherman ME,Suarez AA

    更新日期：2018-07-01 00:00:00

  • Predictors of optimal cytoreduction in patients with newly diagnosed advanced-stage epithelial ovarian cancer: Time to incorporate laparoscopic assessment into the standard of care.

    abstract：:The standard management of advanced-stage ovarian cancer has been a subject of debate, and much controversy remains as to whether patients should have primary cytoreductive surgery followed by chemotherapy or neoadjuvant chemotherapy followed by interval cytoreductive surgery. In addition, there is increasing evidence...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章,评审

    doi：10.1016/j.ygyno.2015.03.049

    authors： Gómez-Hidalgo NR,Martinez-Cannon BA,Nick AM,Lu KH,Sood AK,Coleman RL,Ramirez PT

    更新日期：2015-06-01 00:00:00

  • Fertility-sparing options for early stage cervical cancer.

    abstract：OBJECTIVE:To review the literature on fertility-sparing options for women with early stage cervical cancer and outline patient selection criteria, operative, oncologic, and pregnancy outcomes. METHODS:The literature was searched using MEDLINE (OVID: 1950 through October 2009) and EMBASE (OVID: 1988 through October 200...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章,评审

    doi：10.1016/j.ygyno.2010.01.039

    authors： Gien LT,Covens A

    更新日期：2010-05-01 00:00:00

  • Endometrial pathologies associated with postmenopausal tamoxifen treatment.

    abstract：OBJECTIVE:To evaluate various endometrial pathologies described in association with postmenopausal tamoxifen treatment, as well as the clinical aspects of these endometrial pathologies. METHODS:A search was made in PUB MED for all studies published in English, up to the end of 2003, reporting on endometrial pathologie...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章,评审

    doi：10.1016/j.ygyno.2004.03.048

    authors： Cohen I

    更新日期：2004-08-01 00:00:00

  • A multicenter evaluation of adjuvant therapy in women with optimally resected stage IIIC endometrial cancer.

    abstract：OBJECTIVE:To determine if there is an advantage to combination chemotherapy and radiation for optimally resected stage IIIC endometrial cancer (EC). METHODS:A multicenter retrospective analysis of patients with EC from 1991 to 2008 was conducted. Inclusion criteria were lymph node assessment and optimally resected dis...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.ygyno.2012.10.010

    authors： Secord AA,Geller MA,Broadwater G,Holloway R,Shuler K,Dao NY,Gehrig PA,O'Malley DM,Finkler N,Havrilesky LJ

    更新日期：2013-01-01 00:00:00

  • Thromboembolic events in patients with cervical carcinoma: Incidence and effect on survival.

    abstract：OBJECTIVES:The purpose of this study was to determine whether thromboembolic events (TE) in cervical cancer patients are associated with survival by comparing the survival of patients with and without thromboembolic events over a seven year period. METHODS:Utilizing a retrospective chart review we identified patients ...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2009.01.021

    authors： Jacobson G,Lammli J,Zamba G,Hua L,Goodheart MJ

    更新日期：2009-05-01 00:00:00

  • Homologous recombination deficiency real-time clinical assays, ready or not?

    abstract：:Cancers with deficiencies in homologous recombination-mediated DNA repair (HRR) demonstrate improved clinical outcomes and increased survival. Approximately 50% of high-grade serous ovarian cancers (HGSOC) exhibit homologous recombination deficiency (HRD). HRD can be caused by germline or somatic mutations of genes in...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章,评审

    doi：10.1016/j.ygyno.2020.08.035

    authors： Fuh K,Mullen M,Blachut B,Stover E,Konstantinopoulos P,Liu J,Matulonis U,Khabele D,Mosammaparast N,Vindigni A

    更新日期：2020-12-01 00:00:00

  • Trastuzumab with carboplatin/paclitaxel for treatment of advanced stage and recurrent uterine papillary serous carcinoma: A cost-effectiveness analysis.

    abstract：OBJECTIVE:Uterine papillary serous carcinoma (UPSC) is a variant of endometrial cancer that is aggressive and associated with poor outcomes. We sought to evaluate the cost effectiveness of carboplatin/paclitaxel alone versus carboplatin/paclitaxel with trastuzumab among patients with Her2/neu-positive advanced or recur...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2020.10.018

    authors： Batman S,Bohn J,Weisenberger MW,Hersh A,Bruegl A,Caughey A,Winter W 3rd

    更新日期：2021-01-01 00:00:00

  • Role of PET or PET/CT in the post-therapy surveillance of uterine sarcoma.

    abstract：OBJECTIVE:To evaluate the clinical accuracy and clinical impact of positron emission tomography (PET) or positron emission tomography/computed tomography (PET/CT) in detecting and treating tumor recurrence in patients with treated uterine sarcoma. METHODS:Results of 36 patients who underwent PET or PET/CT in post-ther...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2008.01.030

    authors： Park JY,Kim EN,Kim DY,Suh DS,Kim JH,Kim YM,Kim YT,Nam JH

    更新日期：2008-05-01 00:00:00

  • Advanced ovarian carcinoma presenting with a cerebrovascular accident.

    abstract：:Ovarian carcinoma usually presents in an indolent manner, most often nonspecifically with complaints of abdominal pain or swelling, bloating, constipation, anorexia, early satiety, and evidence of ascites. We present a case of ovarian cancer with a cerebrovascular accident (CVA) as the presenting symptom, with minimal...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1006/gyno.1998.5053

    authors： Shamonki MI,Squatrito RC,Welander CE

    更新日期：1998-08-01 00:00:00

  • Cell proliferation in ovarian carcinoma: superior accuracy of S-phase fraction (SPF) by DNA labeling index versus flow cytometric SPF, lack of independent prognostic power for SPF and DNA ploidy, and limited effect of SPF on tumor growth rate.

    abstract：OBJECTIVES:The goal of this work was to test the hypotheses that S-phase fraction (SPF) by DNA labeling index (SPF-LI) would predict the course of the disease for ovarian/peritoneal carcinomas and that SPF-LI would correlate better with pathologic classification and outcome than SPF by DNA flow cytometry (SPF-F). METH...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1006/gyno.2001.6184

    authors： Meyer JS,Gersell DJ,Yim S

    更新日期：2001-06-01 00:00:00

  • Accuracy of diffusion-weighted echo-planar MR imaging and ADC mapping in the evaluation of residual cervical carcinoma after radiation therapy.

    abstract：OBJECTIVES:The impact of diffusion-weighted imaging (DWI) and apparent diffusion coefficients (ADCs) of MR imaging on the evaluation of residual Uterine Cervical Carcinoma after Radiation Therapy, in addition to conventional MR images. METHODS:Fourty-nine women presenting with a uterine cervical cancer were examined w...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2011.06.009

    authors： Levy A,Caramella C,Chargari C,Medjhoul A,Rey A,Zareski E,Boulet B,Bidault F,Dromain C,Balleyguier C

    更新日期：2011-10-01 00:00:00

  • Chemotherapy may be more effective in highly proliferative ovarian carcinomas--a translational research subprotocol of a prospective randomized phase III study (AGO-OVAR 3 protocol).

    abstract：OBJECTIVE:Proliferative activity (PA) may be an indicator of a neoplasm's malignant potential, and it has been described as a prognostic factor in different malignant tumors. It was our aim to study the prognostic significance of PA defined by Ki-S5 and Ki-S2 immunohistochemical staining in a large homogeneously treate...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2006.01.037

    authors： Kommoss S,du Bois A,Schmidt D,Parwaresch R,Pfisterer J,Kommoss F

    更新日期：2006-10-01 00:00:00

  • The impact of written information and counseling (WOMAN-PRO II Program) on symptom outcomes in women with vulvar neoplasia: A multicenter randomized controlled phase II study.

    abstract：OBJECTIVE:To determine whether written information and/or counseling based on the WOMAN-PRO II Program decreases symptom prevalence in women with vulvar neoplasia by a clinically relevant degree, and to explore the differences between the 2 interventions in symptom prevalence, symptom distress prevalence, and symptom e...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.ygyno.2017.04.024

    authors： Raphaelis S,Mayer H,Ott S,Mueller MD,Steiner E,Joura E,Senn B

    更新日期：2017-07-01 00:00:00

  • Endometrial cancer surgery in Arizona: a statewide analysis of access to care.

    abstract：OBJECTIVES:To investigate access to surgical care for endometrial cancer in Arizona. METHODS:The Arizona HealthQuery (AZHQ) data warehouse with claims information on over 7 million patients in Arizona was searched using the International Classification of Disease (ICD-9) codes and Current Procedural Terminology (CPT) ...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2010.11.028

    authors： Benjamin I,Dalton H,Qiu Y,Cayco L,Johnson WG,Balducci J

    更新日期：2011-04-01 00:00:00

  • Advanced ovarian carcinoma diagnosed during pregnancy in a patient with human immunodeficiency virus infection.

    abstract：:Many malignancies appear to occur with increased frequency and aggressive patterns of spread in patients seropositive for human immunodeficiency virus (HIV). The relationship between HIV infection and cervical neoplasia suggests that these patients present with more advanced disease and demonstrate poor response to th...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1006/gyno.1993.1224

    authors： Buckley SL,Molpus K,Carr MB,Jones HW 3rd

    更新日期：1993-09-01 00:00:00

  • Incidence of vulvar high-grade precancerous lesions and cancer in Denmark before and after introduction of HPV vaccination.

    abstract：OBJECTIVE:To assess the incidence of vulvar high-grade precancerous lesions and cancer in Denmark during 1997-2018. METHODS:We identified incident vulvar cancer cases in the Danish Cancer Registry and incident cases of vulvar precancerous lesions in the Danish Pathology Register. We calculated age-standardized inciden...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2020.03.030

    authors： Rasmussen CL,Thomsen LT,Aalborg GL,Kjaer SK

    更新日期：2020-06-01 00:00:00

  • Comparison of ERCC1/XPF genetic variation, mRNA and protein levels in women with advanced stage ovarian cancer treated with intraperitoneal platinum.

    abstract：OBJECTIVE:Approximately 20% of patients receiving platinum-based chemotherapy for epithelial ovarian cancer (EOC) are refractory or develop early recurrence. Identifying these patients early could reduce treatment-associated morbidity and allow quicker transfer to more effective therapies. Much attention has focused on...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2012.05.006

    authors： Deloia JA,Bhagwat NR,Darcy KM,Strange M,Tian C,Nuttall K,Krivak TC,Niedernhofer LJ

    更新日期：2012-09-01 00:00:00