Contracting for professional service agreements.


:A review of several professional service agreements (PSA) of managed care organizations which contract with gynecologic oncologists in the Southern California area demonstrates several distinct patterns of practice restrictions and financial benefits which can help guide the physician who is considering signing such an agreement. These contracts must be evaluated in a manner similar to any business transaction as they are legally binding and can enhance or adversely impact one's clinical practice. Their advantages include increased numbers of referrals resulting in higher practice income; however, their disadvantages include practice restrictions which can adversely impact office overhead, practice efficiency, and the ability to deliver quality medical care. General guidelines to physicians evaluating a PSA include (1) avoiding "hold harmless" clauses, (2) avoiding contracts which tie enrollment in one plan to others, (3) the need to enter any verbal agreements by managed care administrators into the contract language, and (4) avoidance of actions which might be construed as being in violation of antitrust activities. Furthermore, physicians must avoid contracts which will result in the uncontrolled growth of a practice beyond its capabilities for expansion.


Gynecol Oncol


Gynecologic oncology


Berman ML




Has Abstract


1995-08-01 00:00:00














  • Genetic variants in HLA-DP/DQ contribute to risk of cervical cancer: a two-stage study in Chinese women.

    abstract:OBJECTIVE:Human leukocyte antigens (HLA) play an important role in presenting virus antigens to immune cells that are responsible for the clearance of virus-infected cells and tumor cells. Herein, we evaluated whether genetic variants of HLA-DP and HLA-DQ are associated with cervical cancer risk. METHODS:We genotyped ...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Jiang J,Li N,Shen Y,Liu J,Liu L,Du J,Lei Y,Wen Y,Yang L,Guo L,Zhang K,Qiang F,Wang S,Hu Z,Dai M,Shen H

    更新日期:2013-05-01 00:00:00

  • Chronic abdominal pain secondary to omental J-flap: report of two patients.

    abstract::Two patients with a history of stage IB cervical cancer who had undergone prior radical abdominal hysterectomy, omental J-flap placement, and postoperative whole pelvic radiation therapy required subsequent exploratory laparotomy with resection of omental J-flap for treatment of chronic abdominal pain 5 and 2 years, r...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Patsner B

    更新日期:1999-09-01 00:00:00

  • The timing of normalization of CA-125 levels during primary chemotherapy is predictive of survival in patients with epithelial ovarian cancer.

    abstract:OBJECTIVE:To determine if the timing of normalization of CA-125 levels during primary chemotherapy for epithelial ovarian cancer (EOC) could predict survival. METHODS:Patients who reached a complete clinical response for EOC with primary taxane/platinum-based chemotherapy were eligible. Patient demographics, chemother...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Rocconi RP,Matthews KS,Kemper MK,Hoskins KE,Huh WK,Straughn JM Jr

    更新日期:2009-08-01 00:00:00

  • Fatty acid composition of lysophosphatidic acid and lysophosphatidylinositol in plasma from patients with ovarian cancer and other gynecological diseases.

    abstract:OBJECTIVE:We previously reported that plasma levels of total lysophosphatidic acid (LPA) represented a potential biomarker for ovarian cancer and other gynecological cancers [1]. However, total LPA is composed of different LPA species with distinct fatty acid chains. The major objective of the current study, therefore,...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Shen Z,Wu M,Elson P,Kennedy AW,Belinson J,Casey G,Xu Y

    更新日期:2001-10-01 00:00:00

  • Gestational trophoblastic diseases: 1. Pathophysiology of hyperglycosylated hCG.

    abstract:OBJECTIVE:Hyperglycosylated hCG (hCG-H) is a glycosylation variant of hCG produced by cytotrophoblast cells at implantation of pregnancy and in choriocarcinoma. We investigated the biological function of hCG-H in invasion in vitro and in vivo and the use of hCG-H antibodies in blocking tumorigenesis and cancer growth i...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Cole LA,Dai D,Butler SA,Leslie KK,Kohorn EI

    更新日期:2006-08-01 00:00:00

  • Clinical pharmacology of intraperitoneal cisplatin.

    abstract::The clinical pharmacology of cisplatin was determined in six patients with malignant ascites secondary to ovarian cancer, and in one patient with peritoneal mesothelioma, following intraperitoneal administration of cisplatin (25-60 mg/m2). The drug was administered in 1 liter of normal saline as a 15- to 30-min infusi...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Lopez JA,Krikorian JG,Reich SD,Smyth RD,Lee FH,Issell BF

    更新日期:1985-01-01 00:00:00

  • Positron emission tomography/computed tomography imaging for the detection of recurrent ovarian and fallopian tube carcinoma: a retrospective review.

    abstract:PURPOSE:Imaging modalities to evaluate ovarian/fallopian tube cancer patients for recurrence are limited. Positron emission tomography (PET), computed tomography (CT), magnetic resonance imaging (MRI), and ultrasound lack the sensitivity to consistently detect recurrence or measurable disease in these patients. A new t...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Makhija S,Howden N,Edwards R,Kelley J,Townsend DW,Meltzer CC

    更新日期:2002-04-01 00:00:00

  • Advanced endometrial cancer detected at 7 months after childbirth.

    abstract::It is very rare to find endometrial cancers arising within a short period following childbirth, presumably because pregnancy has a protective effect against endometrial cancer mediated by elevated secretion of progesterone. We present the case of a 30-year-old Japanese woman with stage IIIC endometrial cancer that was...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,评审


    authors: Kodama J,Yoshinouchi M,Miyagi Y,Kobashi Y,Kamimura S,Okuda H,Kudo T

    更新日期:1997-03-01 00:00:00

  • Characterization of the protein synthesis independent TNFalpha lytic mechanism in human ovarian and cervical carcinoma cell lines.

    abstract::The analysis of the lytic mechanism initiated by TNFalpha in three human ovarian cell lines (CAOV-3, SK-OV-3, and OVCAR-3) and in three human cervical cell lines (SIHa, HT-3, and ME-180) in the presence of inhibitors of protein synthesis indicates that this lytic mechanism is similar to the protein synthesis-independe...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Powell CB,Scott JH,Collins JL

    更新日期:1996-07-01 00:00:00

  • Disparities in surgical management of endometrial cancers in a public healthcare system: A question of equity.

    abstract:OBJECTIVE:Timely surgery has been shown to impact outcome in endometrial cancer patients. Social determinants of health (SDH) are associated with adverse cancer outcomes. We sought to evaluate the association of SDH with surgical treatment indicators in endometrial cancer patients in a public healthcare system. METHOD...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Helpman L,Pond GR,Elit L,Anderson LN,Seow H

    更新日期:2020-11-01 00:00:00

  • A longitudinal study of antigen expression in epithelial ovarian cancer.

    abstract::The extent to which the antigenic phenotype of human epithelial ovarian cancer changes during the course of the disease is an issue that must be addressed in order to maximize the potential of antibody-directed imaging and therapy. We have obtained tumor specimens at two separate operations from ten patients with epit...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Rubin SC,Finstad CL,Hoskins WJ,Federici MG,Lloyd KO,Lewis JL Jr

    更新日期:1989-09-01 00:00:00

  • Clear cell carcinoma of the ovary: a report from the first Ovarian Clear Cell Symposium, June 24th, 2010.

    abstract:OBJECTIVES:Recent literature has highlighted histological types of ovarian carcinoma as distinct diseases, each with unique clinical and molecular features. Historically, the diagnosis of ovarian clear cell carcinoma (CCC) has been of concern to both patients and physicians due to reports that CCC is associated with a ...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,评审


    authors: Anglesio MS,Carey MS,Köbel M,Mackay H,Huntsman DG,Vancouver Ovarian Clear Cell Symposium Speakers.

    更新日期:2011-05-01 00:00:00

  • Carcinoma of the cervix in association with uterine prolapse.

    abstract:BACKGROUND:Carcinoma of the cervix and a prolapsed uterus are common diseases in underdeveloped countries, but their association is quite rare. CASE:We report here the clinical characteristics of two Brazilian patients with carcinoma of the uterine cervix associated with a third-degree prolapsed uterus. The patients, ...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: da Silva BB,da Costa Araújo R,Filho CP,Melo JA

    更新日期:2002-02-01 00:00:00

  • Evaluation of the performance of the ACS NSQIP surgical risk calculator in gynecologic oncology patients undergoing laparotomy.

    abstract:OBJECTIVE:The objective of this study was to evaluate the ability of the American College of Surgeons (ACS) National Surgical Quality Improvement Program (NSQIP) surgical risk calculator to predict complications in gynecologic oncology patients undergoing laparotomy. METHODS:A chart review of patients who underwent la...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Rivard C,Nahum R,Slagle E,Duininck M,Isaksson Vogel R,Teoh D

    更新日期:2016-05-01 00:00:00

  • Neuropilin-1 promotes unlimited growth of ovarian cancer by evading contact inhibition.

    abstract:OBJECTIVE:Neuropilin-1 (NRP-1) is a receptor for both semaphorin and vascular endothelial growth factor and is up-regulated in a variety of human cancers. While there are some reports of NRP-1 expression in ovarian neoplasm, those results differ in pattern of its expression and its role in ovarian cancer is still uncle...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Baba T,Kariya M,Higuchi T,Mandai M,Matsumura N,Kondoh E,Miyanishi M,Fukuhara K,Takakura K,Fujii S

    更新日期:2007-06-01 00:00:00

  • Chemoradiation in locally advanced cervical carcinoma: an analysis of cisplatin dosing and other clinical prognostic factors.

    abstract:OBJECTIVES:The aim of this study was to evaluate the effect of number of chemotherapy cycles and other clinical and pathologic factors on progression-free (PFS) and overall survival (OS) in patients with newly diagnosed cervical cancer. METHODS:We identified 118 patients with locally advanced cervical cancer (stages I...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Nugent EK,Case AS,Hoff JT,Zighelboim I,DeWitt LL,Trinkhaus K,Mutch DG,Thaker PH,Massad LS,Rader JS

    更新日期:2010-03-01 00:00:00

  • Postsurgical surveillance of patients with FIGO stage I/II endometrial adenocarcinoma.

    abstract:OBJECTIVE:To examine the effect of postsurgical surveillance on survival of patients with FIGO stage I/II endometrial adenocarcinoma. METHODS:We examined the records of 354 patients who underwent primary surgical therapy for FIGO stage I/II endometrial adenocarcinoma. In patients who developed recurrent disease, we de...

    journal_title:Gynecologic oncology

    pub_type: 临床试验,杂志文章


    authors: Berchuck A,Anspach C,Evans AC,Soper JT,Rodriguez GC,Dodge R,Robboy S,Clarke-Pearson DL

    更新日期:1995-10-01 00:00:00

  • Cyclin E as a potential therapeutic target in high grade serous ovarian cancer.

    abstract::Cyclin E1 (CCNE1) gene amplification occurs in approximately 20% of ovarian high grade serous carcinoma (HGSC) and is associated with chemotherapy resistance and, in some studies, overall poor prognosis. The role of cyclin E1 in inducing S phase entry relies upon its interactions with cyclin dependent kinases (CDK), s...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,评审


    authors: Kanska J,Zakhour M,Taylor-Harding B,Karlan BY,Wiedemeyer WR

    更新日期:2016-10-01 00:00:00

  • Colorectal function preservation in posterior and total supralevator exenteration for gynecologic malignancies: an 89-patient series.

    abstract:OBJECTIVE:The objective of this study was to analyze our experience with colorectal function preservation at the time of pelvic exenteration. METHODS:Between January 1980 and December 2001, 201 pelvic exenterations for gynecologic malignancies were performed in our hospital. Ninety-eight were supralevator exenteration...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Moutardier V,Houvenaeghel G,Lelong B,Mokart D,Delpero JR

    更新日期:2003-04-01 00:00:00

  • Comprehensive genomic profiling reveals inactivating SMARCA4 mutations and low tumor mutational burden in small cell carcinoma of the ovary, hypercalcemic-type.

    abstract:OBJECTIVE:Small cell carcinoma of the ovary, hypercalcemic-type (SCCOHT) is a rare, extremely aggressive neoplasm that usually occurs in young women and is characterized by deleterious germline or somatic SMARCA4 mutations. We performed comprehensive genomic profiling (CGP) to potentially identify additional clinically...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Lin DI,Chudnovsky Y,Duggan B,Zajchowski D,Greenbowe J,Ross JS,Gay LM,Ali SM,Elvin JA

    更新日期:2017-12-01 00:00:00

  • Choriocarcinoma in a term placenta with maternal metastases.

    abstract::Choriocarcinoma of the nonmolar placenta is presumptively a rare entity and is usually associated with widespread maternal metastases at the time of diagnosis. Nonmetastatic disease goes unrecognized and undiagnosed because placental carcinoma can be limited to a few villi, and grossly evident disease is often misinte...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,评审


    authors: Christopherson WA,Kanbour A,Szulman AE

    更新日期:1992-08-01 00:00:00

  • Mesorectal lymph node involvement and prognostic implications at total pelvic exenteration for gynecologic malignancies.

    abstract:OBJECTIVES:To determine the incidence and prognostic implications of positive mesorectal lymph nodes in patients undergoing total pelvic exenteration for recurrent gynecologic malignancies. METHODS:We performed a retrospective chart review of all patients who had undergone total pelvic exenteration for a gynecologic m...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Mourton SM,Chi DS,Sonoda Y,Alektiar KM,Venkatraman ES,Barakat RR,Abu-Rustum NR

    更新日期:2006-03-01 00:00:00

  • Determinants of response to a cisplatin-based regimen as neoadjuvant chemotherapy in stage IB-IIB invasive cervical cancer.

    abstract::The response rate and the determinants of response to a cisplatin-based regimen of neodjuvant chemotherapy (NACT) in women with a histologically confirmed first-diagnosis of invasive bulky stage IB-IIB cervical cancer are analyzed. A total of 79 cases were treated with cisplatin (40 mg/m2) each 7 days for seven course...

    journal_title:Gynecologic oncology

    pub_type: 临床试验,杂志文章


    authors: Bolis G,van Zainten-Przybysz I,Scarfone G,Zanaboni F,Scarabelli C,Tateo S,Calabrese M,Parazzini F

    更新日期:1996-10-01 00:00:00

  • Reconstructive surgery following resection of primary vulvar cancers.

    abstract:OBJECTIVE:This study describes the surgical treatment and follow-up of 213 patients with primary vulvar cancer; particular attention is given to reconstructive surgical procedures. METHODS:The clinical and pathological parameters of the patients were recorded according to standardized procedures, and the data concerni...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Weikel W,Hofmann M,Steiner E,Knapstein PG,Koelbl H

    更新日期:2005-10-01 00:00:00

  • Laparoscopic restaging of early stage invasive adnexal tumors: a 10-year experience.

    abstract:UNLABELLED:Surgical staging of apparent early stage adnexal carcinoma provides indispensable information. A significant number of patients are referred to tertiary centers with inadequate staging information. We report on our experience with late results of laparoscopic restaging procedure in uncompletely managed early...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Leblanc E,Querleu D,Narducci F,Occelli B,Papageorgiou T,Sonoda Y

    更新日期:2004-09-01 00:00:00

  • Standing on the shoulders of giants: Mentorship advice from leaders in the field.

    abstract::This commentary is presenting opinions and advice on mentorship in the field of gynecologic oncology. Eleven academic gynecologic oncologists from across the country were interviewed and their thoughts about mentorship were recorded with recurring themes and ideas described in this commentary. Trust, respect, and mutu...

    journal_title:Gynecologic oncology

    pub_type: 社论


    authors: Boitano TKL,Chi DS,Copeland LJ,Straughn JM Jr

    更新日期:2021-01-27 00:00:00

  • Predictive biomarkers of platinum and taxane resistance using the transcriptomic data of 1816 ovarian cancer patients.

    abstract:OBJECTIVE:The first-line chemotherapy for ovarian cancer is based on a combination of platinum and taxane. To date, no reliable predictive biomarker has been recognized that is capable of identifying patients with pre-existing resistance to these agents. Here, we have established an integrated database and identified t...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Fekete JT,Ősz Á,Pete I,Nagy GR,Vereczkey I,Győrffy B

    更新日期:2020-03-01 00:00:00

  • Implementing specificity of HPV-DNA primary screening in a successful organised cervical cancer prevention programme.

    abstract:OBJECTIVE:This two-arm longitudinal study was performed within a regional organized cervical-cancer-prevention program in which HPV-DNA test is used in primary screening. The aim was to analyze the diagnostic performances of p16INK4a/Ki-67 dual-test and E6/E7-mRNA test in identifying CIN2+ lesion among HPV-DNA positive...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Zappacosta R,Caraceni D,Ciccocioppo L,Rotondo T,Capanna S,Gatta DM,D'Angelo C,Rosini S

    更新日期:2013-03-01 00:00:00

  • Metastatic endometrial cancer in lung and liver: complete and prolonged response to hormonal therapy with progestins.

    abstract::A double complete and prolonged response of metastatic endometrial carcinoma to medroxyprogesterone is reported. A 61-year-old woman with metastatic endometrial carcinoma in lung and liver achieved a complete clinical response with medroxyprogesterone lasting for 2 years. She discontinued the therapy by herself and de...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Crespo C,González-Martín A,Lastra E,García-López J,Moyano A

    更新日期:1999-02-01 00:00:00

  • Epithelial ovarian neoplasms of low malignant potential.

    abstract::This report presents 13 patients with epithelial ovarian neoplasms of low malignant potential. Ten patients had serous tumors, 1 had a mucinous tumor, and 2 had endometrioid tumors. Two had Stage I disease, 4 had Stage II disease, and 7 had Stage III disease. All were treated with melphalan. Second-look laparotomy was...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: O'Quinn AG,Hannigan EV

    更新日期:1985-06-01 00:00:00