Stage IB carcinoma of the cervix with lymph node metastases.

abstract：OBJECTIVE:Australia's HPV vaccination and HPV-based cervical screening programs are changing the landscape in cervical cancer prevention. We aim to identify areas which can make the biggest further impact on cervical cancer burden. This protocol describes the first stage of a program of work called Pathways-Cervix that...

journal_title：Gynecologic oncology

authors： Velentzis LS,Smith MA,Simms KT,Lew JB,Hall M,Hughes S,Yuill S,Killen J,Keane A,Butler K,Darlington-Brown J,Hui H,Brotherton JML,Skinner R,Brand A,Roeske L,Heley S,Carter J,Bateson D,Frazer I,Garland SM,Guy R,H

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVE:ATP-binding Cassette (ABC) transporters are thought to cause multiple drug resistance (MDR) in various carcinomas. Gene expression data from individual transporters in ovarian cancer tissue is contradictory and also scarce for some of them. RNA levels of a panel of ABC transporters were collected and analyzed...

journal_title：Gynecologic oncology

authors： Auner V,Sehouli J,Oskay-Oezcelik G,Horvat R,Speiser P,Zeillinger R

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVE:Some authors have recommended the use of diagnostic laparoscopy as a pretreatment assessment step for conservative hormonal treatment in young women with endometrial cancer. The aim of this study was to determine the incidence of synchronous primary cancer of the endometrium and ovary in young women. METHODS...

journal_title：Gynecologic oncology

authors： Song T,Seong SJ,Bae DS,Suh DH,Kim DY,Lee KH,Lim MC,Lee TS

更新日期：2013-12-01 00:00:00

abstract：:Uterine leiomyosarcoma is the most common type of uterine sarcoma. It is an extremely aggressive malignancy associated with a poor overall prognosis. Women affected may vary in age, but are most often diagnosed in their perimenopausal years. Presenting symptoms may be vague and mimic other benign uterine conditions. P...

journal_title：Gynecologic oncology

authors： Roberts ME,Aynardi JT,Chu CS

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:Our goal was to pragmatically describe patient reported outcomes (PROs) in a typical clinic population of vulvar cancer patients, as prior studies of vulvar cancer PROs have examined clinical trial participants. METHODS:A prospective PRO program was implemented in the Gynecologic Oncology clinic of a tertiar...

journal_title：Gynecologic oncology

authors： Alimena S,Sullivan MW,Philp L,Dorney K,Hubbell H,Del Carmen MG,Goodman A,Bregar A,Growdon WB,Eisenhauer EL,Sisodia RC

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVE:A phase II study was conducted to determine the efficacy of oxaliplatin therapy in patients with previously treated squamous cell carcinoma of the cervix. METHODS:Eligible patients were to have measurable disease and not more than one prior chemotherapy regimen that could include carboplatin or cisplatin but...

journal_title：Gynecologic oncology

authors： Fracasso PM,Blessing JA,Wolf J,Rocereto TF,Berek JS,Waggoner S

更新日期：2003-07-01 00:00:00

abstract：OBJECTIVES:We aimed to define the site-specific patterns of treatment failure in stage IV ovarian cancer. METHODS:Data from all consecutive Mayo Clinic patients with stage IV epithelial ovarian cancer, from 1994 through 2003, were collected and analyzed. Statistical analyses included the chi(2) test and Kaplan-Meier c...

journal_title：Gynecologic oncology

authors： Aletti GD,Podratz KC,Cliby WA,Gostout BS

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Improvements in surgical technique of pelvic exenteration have mainly occurred in the reconstructive phase of the procedure. Quality of life seems to be improved when performing continent rather than non-continent urinary diversion [1]. Unfortunately, Miami continent urinary pouch is a surgical technique not...

journal_title：Gynecologic oncology

authors： Angeles MA,Martínez-Gómez C,Martinez A,Ferron G

更新日期：2018-08-01 00:00:00

abstract：:Immunohistochemical studies were performed to investigate the prognostic significance of p53 protein expression in 46 patients with stage IIIB squamous cell carcinoma of the uterine cervix who were treated with radiation therapy alone. Tumor cells showed p53 protein expression in 29 of 46 patients. The 5-year overall ...

journal_title：Gynecologic oncology

authors： Ebara T,Mitsuhashi N,Saito Y,Sakurai H,Hasegawa M,Takahashi M,Takahashi T,Hayakawa K,Niibe H

更新日期：1996-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the usefulness of pre-operative serum CA-125 in the management of women diagnosed with uterine papillary serous carcinoma (UPSC). We hypothesized that elevated pre-operative levels of serum CA-125 correlate with higher disease stage and poorer prognosis. METHODS:Patients diagnosed with UPSC and m...

journal_title：Gynecologic oncology

authors： Olawaiye AB,Rauh-Hain JA,Withiam-Leitch M,Rueda B,Goodman A,del Carmen MG

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:Comorbidities are known to increase endometrial cancer risk, but the separate and combined impact of these risk factors on endometrial cancer survival remains unclear. This study aimed to determine the associations between metabolic syndrome and its components with disease-free survival, overall survival, end...

journal_title：Gynecologic oncology

authors： Kokts-Porietis RL,McNeil J,Nelson G,Courneya KS,Cook LS,Friedenreich CM

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to profile cervical squamous cell carcinoma in elderly patients undergoing radiation therapy and to study the treatment outcome and side effects of therapy. MATERIALS AND METHODS:A retrospective analysis was carried out from the records of 380 patients with squamous cell carcino...

journal_title：Gynecologic oncology

authors： Sakurai H,Mitsuhashi N,Takahashi M,Yamakawa M,Akimoto T,Hayakawa K,Niibe H

更新日期：2000-04-01 00:00:00

abstract：:Surgical treatment including total abdominal hysterectomy+bilateral salpingo oopherectomy (TAH+BSO) with pelvic and para-aortic lymphadenectomy may not be sufficient to treat cases with advanced endometrial adenocarcinoma (EAC), and in these cases, adjuvant treatments including radiotherapy and/or chemotherapy, are em...

journal_title：Gynecologic oncology

authors： Thangaraju S,Subramani E,Chakravarty B,Chaudhury K

更新日期：2012-11-01 00:00:00

abstract：:Benign cystic mesothelioma is a tumor characteristically found in women during the reproductive years. These tumors are infrequently found after castration or menopause, suggesting some degree of hormonal sensitivity. Such aspects of the tumor suggest a potential role for antiestrogens as medical management and an alt...

journal_title：Gynecologic oncology

authors： Letterie GS,Yon JL

更新日期：1998-07-01 00:00:00

abstract：OBJECTIVE:To review the clinical features, diagnosis, management, and outcomes for the 50 cases of Paget's disease (PD) of the vulva referred to Queensland Centre for Gynaecological Cancer between 1986 and 2009. METHODS:Vulvar PD cases from QCGC were reviewed and analyzed using the computer software Statistical Packag...

journal_title：Gynecologic oncology

authors： Jones IS,Crandon A,Sanday K

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:To investigate the STATs signaling pathway activated by VEGF in human hemopoietic progenitor cells. METHODS:CD34(+) hemopoietic progenitor cells, which isolated from umbilical cord blood, were treated with VEGF or culture supernatant of ovarian carcinoma cell line which could secrete large amount of VEGF, ph...

journal_title：Gynecologic oncology

authors： Ye F,Chen HZ,Xie X,Ye DF,Lu WG,Ding ZM

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:Vulvar synovial cell sarcomas are rare, with only four previously published cases in the literature. Traditionally, the primary management for these tumors has been surgery alone. CASE:We report a case of a large vulvar synovial cell sarcoma in a 50-year-old woman treated with comprehensive combined multimo...

journal_title：Gynecologic oncology

authors： Holloway CL,Russell AH,Muto M,Albert M,Viswanathan AN

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:There are currently limited published data available on the safety and feasibility of the prolonged administration of paclitaxel. The goal of this study was to review the cumulative toxicity associated with the continuous long-term administration of this agent to women with gynecologic cancers. METHODS:Eleve...

journal_title：Gynecologic oncology

authors： Rohl J,Kushner D,Markman M

更新日期：2001-05-01 00:00:00

abstract：OBJECTIVES:The presence of an eosinophilic infiltrate in patients with cervical squamous carcinoma has been shown to correlate with a worse overall survival, suggesting a less effective immune response in these cases. Since type 2 cytokines such as IL-4 and IL-5 are known to attract eosinophilic granulocytes, an immuno...

journal_title：Gynecologic oncology

authors： van Driel WJ,Kievit-Tyson P,van den Broek LC,Zwinderman AH,Trimbos BJ,Fleuren GJ

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:Hec1 (Highly Expressed in Cancer gene 1) has recently been shown to play an important role in the proper segregation of chromosomes during mitosis. Recently, an adenovirus delivery system carrying RNA interference (RNAi) of Hec1 has been reported in a cervical adenocarcinoma model. Adenoviral delivery system...

journal_title：Gynecologic oncology

authors： Numnum TM,Makhija S,Lu B,Wang M,Rivera A,Stoff-Khalili M,Alvarez RD,Zhu ZB,Curiel DT

更新日期：2008-01-01 00:00:00

abstract：:Ovarian cancer is the leading cause of gynecologic cancer deaths in the U.S. The concept of intraperitoneal drug delivery for therapy of intraperitoneal cancers, such as ovarian cancer, arose in the 1960s. The field of intraperitoneal cisplatin therapy for ovarian cancer was initiated in the late 1970s and early 1980s...

journal_title：Gynecologic oncology

authors： Alberts DS,Markman M,Muggia F,Ozols RF,Eldermire E,Bookman MA,Chen T,Curtin J,Hess LM,Liebes L,Young RC,Trimble E

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVE:In vitro data and pilot data suggest that green tea catechins may possess chemopreventive activity for cervical cancer and precursor lesions. We conducted a randomized, double-blind, placebo-controlled trial of Polyphenon E (decaffeinated and enriched green tea catechin extract) in women with persistent human...

journal_title：Gynecologic oncology

authors： Garcia FA,Cornelison T,Nuño T,Greenspan DL,Byron JW,Hsu CH,Alberts DS,Chow HH

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVES:To assess the utility of tumor diameter (TD) for predicting lymphatic dissemination (LD) and determining need for lymphadenectomy following diagnosis of endometrioid endometrial cancer. METHODS:Patients diagnosed with stage I-III endometrioid endometrial cancer during 2003-2013 who underwent pelvic or para-...

journal_title：Gynecologic oncology

authors： Cox Bauer CM,Greer DM,Kram JJF,Kamelle SA

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVES:The aims of the study were to investigate whether an elevated CA 125 level signals malignancies other than ovarian cancer and to find the cause of death for 247 women with elevated values among the 5550 women screened in 1986-1988 in the Stockholm population. METHODS:The Swedish Regional Cancer Registry del...

journal_title：Gynecologic oncology

authors： Sjövall K,Nilsson B,Einhorn N

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVE:To help determine whether global collaborations for prospective gynecologic surgery trials should include hospitals in developing countries, we compared surgical and oncologic outcomes of patients undergoing laparoscopic radical hysterectomy at a large comprehensive cancer center in the United States and a ca...

journal_title：Gynecologic oncology

authors： Pareja R,Nick AM,Schmeler KM,Frumovitz M,Soliman PT,Buitrago CA,Borrero M,Angel G,Reis RD,Ramirez PT

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVE:Cone margin status has been reported to be the most important predictor of residual disease in patients with cervical intraepithelial neoplasia (CIN) undergoing electrosurgical excisional treatment. The primary aim of this study of patients treated with electrosurgical conization was to evaluate the associati...

journal_title：Gynecologic oncology

authors： Costa S,De Nuzzo M,Infante FE,Bonavita B,Marinelli M,Rubino A,Rambelli V,Santini D,Cristiani P,Bucchi L

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:The aim of this paper was to report two cases of extrauterine disease in patients with early stage endometrial cancer (EC) who desired fertility-sparing management. CASES:Two patients presenting an apparent early stage EC and desiring conservative management. The two patients, aged 35 and 36 years old, had ...

journal_title：Gynecologic oncology

authors： Morice P,Fourchotte V,Sideris L,Gariel C,Duvillard P,Castaigne D

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Development of carcinoma in situ in a neovagina is rare. CASE:A case of carcinoma in situ of a neovagina complicated by recurrence after ablative therapy is discussed. Recurrence occurred within 4 months of initial therapy, and a total vaginectomy was performed after the patient declined other therapeutic o...

journal_title：Gynecologic oncology

authors： Lowe MP,Ault KA,Sood AK

更新日期：2001-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the value of the combination of p16 and HPV detection in the screening for cervical cancer. METHODS:186 patients with previous abnormal cervical lesion were studied. After colposcopic examination, two conventional Pap slides were prepared: the first was Papanicolaou-stained and examined by cytolo...

journal_title：Gynecologic oncology

authors： Ekalaksananan T,Pientong C,Sriamporn S,Kongyingyoes B,Pengsa P,Kleebkaow P,Kritpetcharat O,Parkin DM

更新日期：2006-10-01 00:00:00

abstract：OBJECTIVE:We compared the self-sampling performance of the newly designed HerSwab™ device with a physician-collected cervical sample and another self-sample using the cobas® PCR Female swab for the detection of cervical intraepithelial neoplasia (CIN) and cancer. METHODS:Women referred for colposcopy at McGill Univers...

journal_title：Gynecologic oncology

authors： El-Zein M,Bouten S,Louvanto K,Gilbert L,Gotlieb W,Hemmings R,Behr MA,Franco EL,CASSIS Study Group.

更新日期：2018-06-01 00:00:00