A need for laparoscopic evaluation of patients with endometrial carcinoma selected for conservative treatment.

Abstract:

BACKGROUND:The aim of this paper was to report two cases of extrauterine disease in patients with early stage endometrial cancer (EC) who desired fertility-sparing management. CASES:Two patients presenting an apparent early stage EC and desiring conservative management. The two patients, aged 35 and 36 years old, had a grade 1 and grade 2 EC diagnosed after curettage or hysteroscopic resection of a polyp. Ultrasound (US) imaging was normal (ovary). Once informed about the risk of recurrence, both patients opted for conventional therapy (hysterectomy with bilateral salpingo-oophorectomy). A small ovarian carcinoma was found in one patient and isolated positive peritoneal cytology in the other. CONCLUSIONS:These cases seem to suggest that laparoscopic evaluation including adnexal exploration and peritoneal cytology (and possibly pelvic lymphadenectomy) should be performed in patients with early stage EC selected for conservative management to confirm the absence of extrauterine disease.

journal_name

Gynecol Oncol

journal_title

Gynecologic oncology

authors

Morice P,Fourchotte V,Sideris L,Gariel C,Duvillard P,Castaigne D

doi

10.1016/j.ygyno.2004.09.034

subject

Has Abstract

pub_date

2005-01-01 00:00:00

pages

245-8

issue

1

eissn

0090-8258

issn

1095-6859

pii

S0090-8258(04)00786-3

journal_volume

96

pub_type

杂志文章,评审
  • Pilomatricoma-like endometrioid adenosquamous carcinoma of the ovary with neuroendocrine differentiation.

    abstract::A case of high-grade endometrioid adenosquamous carcinoma of the ovary showing pilomatricoma-like areas and neuroendocrine differentiation is presented. The pilomatricoma-like areas were strongly positive for cytokeratin and vimentin, whereas the poorly differentiated areas of the tumor were positive for cytokeratin, ...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1006/gyno.1996.0142

    authors: Fang J,Keh P,Katz L,Rao MS

    更新日期:1996-05-01 00:00:00

  • Effective chemotherapy consisting of bleomycin, vincristine, mitomycin C, and cisplatin (BOMP) for a patient with inoperable vulvar cancer.

    abstract::Combination chemotherapy consisting of bleomycin, vincristine, mitomycin C, and cisplatin (BOMP) was first applied to an inoperable case (57-year-old) with FIGO stage IV (T3N3 + M1B) squamous cell carcinoma of the vulva. After three courses of BOMP therapy, the patient achieved a complete response with few toxic effec...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/0090-8258(90)90156-f

    authors: Shimizu Y,Hasumi K,Masubuchi K

    更新日期:1990-03-01 00:00:00

  • Cytokeratin subunit 19 measured by CYFRA 21-1 assay in follow-up of cervical cancer.

    abstract::The purpose of this study was to evaluate the serum tumor markers CYFRA 21-1 and squamous-cell carcinoma antigen (SCC) in the follow-up of squamous-cell cervical cancer patients. One hundred-ninety-three serum samples, which were collected pretherapeutically and during follow-up of 30 patients suffering from squamous-...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1006/gyno.1995.1071

    authors: Kainz C,Sliutz G,Mustafa G,Bieglmayr C,Koelbl H,Reinthaller A,Gitsch G

    更新日期:1995-03-01 00:00:00

  • Solitary recurrent metastasis of epithelial ovarian cancer in the spleen.

    abstract::In epithelial ovarian cancer, solitary metastasis to and recurrences in the parenchyma of the spleen are rare in the absence of apparent disease in other sites. We report four patients who developed isolated, solitary splenic parenchymal recurrences of their epithelial ovarian adenocarcinomas and underwent a splenecto...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1006/gyno.1993.1059

    authors: Farias-Eisner R,Braly P,Berek JS

    更新日期:1993-03-01 00:00:00

  • Role of high-risk human papillomavirus (HPV) mRNA testing in the prediction of residual disease after conisation for high-grade cervical intraepithelial neoplasia.

    abstract:OBJECTIVE:To evaluate testing for high-risk human papillomavirus (HR HPV) E6/E7 mRNA transcripts 6 months after conisation for cervical intraepithelial neoplasia grade 2 or worse (CIN2+) to determine the risk of residual CIN2+. METHODS:We prospectively followed 344 women treated for CIN2+ by conisation. HR HPV mRNA te...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2011.07.032

    authors: Tropé A,Jonassen CM,Sjøborg KD,Nygård M,Dahl FA,Alfsen GC,Lie AK

    更新日期:2011-11-01 00:00:00

  • Pre-chemotherapy hemoglobin levels and survival in patients with advanced epithelial ovarian cancer who received a first-line taxane/platinum-based regimen: results of a multicenter retrospective Italian study.

    abstract:OBJECTIVE:The aim of this retrospective multicenter study was to assess whether the pre-chemotherapy hemoglobin levels have any impact on the clinical outcome of patients with advanced epithelial ovarian cancer who received a first-line taxane/platinum-based regimen. METHODS:The study was conducted on 315 patients who...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.ygyno.2005.04.012

    authors: Gadducci A,Sartori E,Landoni F,Zola P,Maggino T,Colombo N,Fanucchi A,Chiudinelli F,Lapresa M,Maria Ferrero A

    更新日期:2005-07-01 00:00:00

  • Metastatic serous borderline ovarian tumor in an internal mammary lymph node: a case report and review of the literature.

    abstract::Background. Reports of supradiaphragmatic involvement of lymph nodes by serous borderline ovarian tumors are rare. Case. We describe the finding of metastatic tumor involving an internal mammary lymph node in a 74-year-old patient with serous borderline ovarian tumor. The positive lymph node was found incidentally dur...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,评审

    doi:10.1006/gyno.2001.6234

    authors: Chamberlin MD,Eltabbakh GH,Mount SL,Leavitt BJ

    更新日期:2001-07-01 00:00:00

  • Cell kinetics: a prognostic marker in epithelial ovarian cancer.

    abstract::The proliferative activities (3H-thymidine labeling index, LI) of 72 primary ovarian cancers and 76 metastatic lesions from untreated patients were evaluated. Overall, median LI values for primary and metastatic lesions were similar (7.8 vs 7.0%), but cell kinetics significantly differed in metastases from different s...

    journal_title:Gynecologic oncology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0090-8258(89)90003-6

    authors: Silvestrini R,Daidone MG,Bolis G,Fontanelli R,Landoni F,Andreola S,Colombi R

    更新日期:1989-10-01 00:00:00

  • Metabolic risk factors and mechanisms of disease in epithelial ovarian cancer: A review.

    abstract:OBJECTIVE:Epithelial ovarian cancer continues to be the deadliest gynecologic malignancy. Patients with both diabetes mellitus and obesity have poorer outcomes, yet research correlating metabolic abnormalities, such as metabolic syndrome, to ovarian cancer risk and outcomes is lacking. This article reviews the literatu...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,评审

    doi:10.1016/j.ygyno.2016.10.005

    authors: Craig ER,Londoño AI,Norian LA,Arend RC

    更新日期:2016-12-01 00:00:00

  • Angiomyofibroblastoma of the vulva.

    abstract::Angiomyofibroblastoma is a rare, myxoid tumor of the vulva. To date only 12 cases have been reported in the world literature. Patients are usually premenopausal and present with a vulval mass initially diagnosed as a Bartholin's cyst. The lesions are well circumscribed and range from 0.5 to 12 cm in size. Microscopica...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1006/gyno.1994.1230

    authors: Van der Griend MD,Burda P,Ferrier AJ

    更新日期:1994-09-01 00:00:00

  • Prognostic factors of Krukenberg's tumor.

    abstract:OBJECTIVE:The aim of this study was to determine prognostic factors of metachronous Krukenberg's tumors of gastric origin, thereby helping to establish a therapeutic plan for this rare entity. METHODS:Thirty-four female patients who underwent curative resection of gastric carcinoma from 1987 through 1996 and subsequen...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1006/gyno.2001.6210

    authors: Kim HK,Heo DS,Bang YJ,Kim NK

    更新日期:2001-07-01 00:00:00

  • Determinants of response to a cisplatin-based regimen as neoadjuvant chemotherapy in stage IB-IIB invasive cervical cancer.

    abstract::The response rate and the determinants of response to a cisplatin-based regimen of neodjuvant chemotherapy (NACT) in women with a histologically confirmed first-diagnosis of invasive bulky stage IB-IIB cervical cancer are analyzed. A total of 79 cases were treated with cisplatin (40 mg/m2) each 7 days for seven course...

    journal_title:Gynecologic oncology

    pub_type: 临床试验,杂志文章

    doi:10.1006/gyno.1996.0279

    authors: Bolis G,van Zainten-Przybysz I,Scarfone G,Zanaboni F,Scarabelli C,Tateo S,Calabrese M,Parazzini F

    更新日期:1996-10-01 00:00:00

  • The impact of written information and counseling (WOMAN-PRO II Program) on symptom outcomes in women with vulvar neoplasia: A multicenter randomized controlled phase II study.

    abstract:OBJECTIVE:To determine whether written information and/or counseling based on the WOMAN-PRO II Program decreases symptom prevalence in women with vulvar neoplasia by a clinically relevant degree, and to explore the differences between the 2 interventions in symptom prevalence, symptom distress prevalence, and symptom e...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.ygyno.2017.04.024

    authors: Raphaelis S,Mayer H,Ott S,Mueller MD,Steiner E,Joura E,Senn B

    更新日期:2017-07-01 00:00:00

  • Frozen section diagnoses of 578 ovarian tumors made by pathologists with and without expertise on gynecologic pathology.

    abstract:OBJECTIVE:Frozen section is an important diagnostic tool to determine the nature of the ovarian masses intraoperatively. The optimal surgical treatment can be achieved by classifying the masses as benign, borderline and malignant. The aim of this retrospective study was to evaluate the accuracy of frozen section diagno...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2011.06.030

    authors: Bige O,Demir A,Saygili U,Gode F,Uslu T,Koyuncuoglu M

    更新日期:2011-10-01 00:00:00

  • Retinoblastoma protein expression in ovarian epithelial neoplasms.

    abstract::Progress has been made in identifying the molecular changes that occur in ovarian carcinoma; still our understanding of these changes and their interactions remains incomplete. In the present study the authors examined the expression of retinoblastoma protein, a tumor suppressor protein, in a spectrum of ovarian epith...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1006/gyno.1998.5015

    authors: Niemann TH,Trgovac TL,McGaughy VR,Lewandowski GS,Copeland LJ

    更新日期:1998-06-01 00:00:00

  • Multicystic benign mesothelioma of the peritoneum presenting as postmenopausal bleeding and a solitary pelvic cyst--a case report.

    abstract:BACKGROUND:All non-invasive diagnostic algorithms suffer from diagnostic uncertainty in discriminating benign from malignant adnexal masses. CASE:We present a case where the identification of a large solitary multiloculated pelvic cyst in a woman with postmenopausal bleeding was shown to be multifocal multicystic beni...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2003.09.036

    authors: Varma R,Wallace R

    更新日期:2004-01-01 00:00:00

  • Placental site trophoblastic tumor: A study of 55 cases and review of the literature emphasizing factors of prognostic significance.

    abstract:OBJECTIVE:The placental site trophoblastic tumor is a rare form of gestational trophoblastic disease. Fifteen percent of reported cases have been fatal, but predicting behavior in individual patients has been challenging. METHODS:The clinical, gross and histopathological features of 55 cases and 180 cases in the liter...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2005.08.058

    authors: Baergen RN,Rutgers JL,Young RH,Osann K,Scully RE

    更新日期:2006-03-01 00:00:00

  • Sarcoma in association with multimodality management of vulvar cancer: two case reports.

    abstract:BACKGROUND:Radiation-induced or -associated sarcoma is a rare event which has been well described in the literature. However, this entity has been infrequently described in association with genital tract malignancies. To our knowledge it has never been described in association with the management of vulvar cancer. CAS...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1006/gyno.2001.6139

    authors: Hyde S,Uitterhoeve LJ,Schilthuis MS,ten Kate FJ,van der Velden J

    更新日期:2001-05-01 00:00:00

  • Biologic therapeutics and molecular profiling to optimize wound healing.

    abstract::Non-healing wounds represent a significant cause of morbidity and mortality for a large portion of the adult population. Wounds that fail to heal are entrapped in a self-sustaining cycle of chronic inflammation leading to the destruction of the extracellular matrix. Among cancer patients, malnutrition, radiation, phys...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,评审

    doi:10.1016/j.ygyno.2008.07.052

    authors: Menke MN,Menke NB,Boardman CH,Diegelmann RF

    更新日期:2008-11-01 00:00:00

  • Radical hysterectomy followed by tailored postoperative therapy in the treatment of stage IB2 cervical cancer: feasibility and indications for adjuvant therapy.

    abstract:OBJECTIVE:To determine the outcome, complications and likelihood of requiring adjuvant therapy of patients with stage IB2 cervical cancer treated with primary radical hysterectomy and lymph node dissection. METHODS:Clinical and pathologic data between 1985 and 1999 were reviewed. Associations between clinical and path...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2004.04.016

    authors: Yessaian A,Magistris A,Burger RA,Monk BJ

    更新日期:2004-07-01 00:00:00

  • Long-term results of fertility-sparing treatment for early-stage cervical cancer.

    abstract:OBJECTIVE:To evaluate the long-term outcomes of young early stage cervical cancer patients wishing to preserve their childbearing potential. METHODS:Data of young (aged <40 years) patients with early stage cervical cancer were prospectively collected. All patients with stage IA2, IB1 and IB2 cervical cancer were inclu...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2019.04.007

    authors: Bogani G,Chiappa V,Vinti D,Somigliana E,Filippi F,Murru G,Murgia F,Martinelli F,Ditto A,Raspagliesi F

    更新日期:2019-07-01 00:00:00

  • The "real-life" variability of CA-125 in ovarian cancer patients.

    abstract:BACKGROUND:The serum CA-125 antigen value has proven to be useful in predicting changes that affect prognosis and management of ovarian cancer; however, interpreting variations in the tumor marker is still not well-defined. Our goal was to further understand the analytical variability of CA-125 in a conventional hospit...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2006.02.010

    authors: Tso E,Elson P,Vanlente F,Markman M

    更新日期:2006-10-01 00:00:00

  • The additional value of endometrial sampling in the early detection of endometrial cancer in women with Lynch syndrome.

    abstract:OBJECTIVE:Based on previous studies, standard gynecological screening consisting of annual transvaginal ultrasonography (TVU) was added with endometrial sampling in women with Lynch syndrome (LS). The aim of this study was to evaluate the additional value of endometrial sampling in detecting (pre)malignancies of the en...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2013.05.032

    authors: Helder-Woolderink JM,De Bock GH,Sijmons RH,Hollema H,Mourits MJ

    更新日期:2013-11-01 00:00:00

  • Outcome of endometrial carcinoma patients with involvement of the uterine serosa.

    abstract:OBJECTIVE:The goal of this work was to evaluate the outcome of endometrial carcinoma patients undergoing primary surgery who have serosal involvement (SI). METHODS:Between 1980 and 1998, 562 women underwent primary surgery for endometrial cancer at the University of Chicago. Thirty-nine were noted to have SI. FIGO sta...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1006/gyno.2001.6189

    authors: Ashman JB,Connell PP,Yamada D,Rotmensch J,Waggoner SE,Mundt AJ

    更新日期:2001-08-01 00:00:00

  • Incidence and risk factors for lower limb lymphedema associated with endometrial cancer: Results from a prospective, longitudinal cohort study.

    abstract:BACKGROUND:Evidence on the incidence and risk factors for lower limb lymphedema (LLL) associated with endometrial cancer is limited. Our objective was to use data from a prospective, longitudinal gynecological cancer cohort study to determine LLL incidence up to 24 months post-diagnosis of endometrial cancer and to exp...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2020.04.702

    authors: Pigott A,Obermair A,Janda M,Vagenas D,Ward LC,Reul-Hirche H,Hayes SC

    更新日期:2020-08-01 00:00:00

  • Recurrent and persistent squamous cell cervical carcinoma in women under age 35.

    abstract::Forty-five patients with invasive cervical squamous cell carcinoma were registered in the Tom Baker Cancer Centre from 1980 to 1985. The natural history of 22 patients (48.9%) who developed persistent or recurrent disease including 11 Stage IB, 8 Stage IIB, and 3 Stage IIIB is reported. Only one patient who had the un...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/0090-8258(88)90020-0

    authors: Stuart GC,Robertson DI,Fedorkow DM,Duggan MA,Nation JG

    更新日期:1988-06-01 00:00:00

  • Immunotherapy and radiation combinatorial trials in gynecologic cancer: A potential synergy?

    abstract::Immunotherapy (IO) is an important new pillar in the treatment of solid tumors, and the integration of IO agents with chemotherapy, targeted therapy, surgery and radiation has yet to be defined. As preclinical and clinical studies have described synergistic activity with the combination of radiation and immunotherapy,...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,评审

    doi:10.1016/j.ygyno.2019.03.255

    authors: Lee L,Matulonis U

    更新日期:2019-07-01 00:00:00

  • Trends among gynecologic oncology inpatient deaths: is end-of-life care improving?

    abstract:OBJECTIVE:The objective was to describe trends over time in key factors surrounding end-of-life care on a gynecologic oncology service at a tertiary cancer center. METHODS:Patients with gynecologic cancers who were hospitalized and died at our institution between 1992 and 1997 were identified using institutional datab...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1006/gyno.2002.6616

    authors: Dalrymple JL,Levenback C,Wolf JK,Bodurka DC,Garcia M,Gershenson DM

    更新日期:2002-05-01 00:00:00

  • Lymph node dissection in endometrial cancer and clinical outcome: A population-based study in 5546 patients.

    abstract:BACKGROUND:According to current treatment guidelines, comprehensive surgical staging procedures in endometrial cancer confined to the uterus depend on uterine risk factors: a systematic lymph node dissection (LND) is recommended in high risk patients and should be omitted in low risk patients. Its role in intermediate ...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2019.04.002

    authors: Pölcher M,Rottmann M,Brugger S,Mahner S,Dannecker C,Kiechle M,Brambs C,Grab D,Anthuber C,von Koch F,Schnelzer A,Engel J

    更新日期:2019-07-01 00:00:00

  • Gonadotropin stimulation of MLS human epithelial ovarian carcinoma cells augments cell adhesion mediated by CD44 and by alpha(v)-integrin.

    abstract:OBJECTIVE:The goal of this work was to evaluate the involvement of gonadotropins in the regulation of adhesion of human epithelial ovarian carcinoma. We studied two pathways that were previously implicated in the metastatic implantation of ovarian carcinoma to the peritoneum, namely hyaluronan-CD44 and RGD-integrin med...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1006/gyno.2001.6512

    authors: Schiffenbauer YS,Meir G,Maoz M,Even-Ram SC,Bar-Shavit R,Neeman M

    更新日期:2002-02-01 00:00:00