Multicystic benign mesothelioma of the peritoneum presenting as postmenopausal bleeding and a solitary pelvic cyst--a case report.

abstract：OBJECTIVE:Wee1-like kinase (Wee1) is a tyrosine kinase which negatively regulates entry into mitosis at the G2 to M-phase transition and has a role in inhibition of unscheduled DNA replication in S-phase. The present study investigated the clinical role of Wee1 in advanced-stage (FIGO III-IV) ovarian serous carcinoma. ...

journal_title：Gynecologic oncology

authors： Slipicevic A,Holth A,Hellesylt E,Tropé CG,Davidson B,Flørenes VA

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:The prognosis of cancer patients with distant metastases is extremely poor. CASE:A 51-year-old Japanese woman with Stage IIIc serous cystoadenocarcinoma of the ovary achieved complete remission. At 30 and 39 months after the initiation of therapy, solitary brain and then spleen metastases without intraperit...

journal_title：Gynecologic oncology

authors： Mikami M,Suzuki A,Takehara K,Komiyama S,Ishikawa M,Hirose T

更新日期：2003-08-01 00:00:00

abstract：:The distribution of colon--ovarian tumor antigen (COTA) and colon-specific antigen (CSA) was studied immunohistochemically in gynecologic tumors. The antigens were absent in the serous benign tumors of the ovary and in the normal ovarian tissues, whereas they were detected in some of the mucinous benign tumors. COTA a...

journal_title：Gynecologic oncology

authors： Ueda G,Shimizu C,Saito J,Tanaka Y,Inoue M,Tanizawa O

更新日期：1989-10-01 00:00:00

abstract：OBJECTIVES:Most ovarian cancer patients are diagnosed at an advanced stage (67%) and prospects for significant improvement in survival reside in early diagnosis. While expression patterns of a recently identified biomarker family, microRNA, appear to be characteristic of tumor type and developmental origin, microRNA pr...

journal_title：Gynecologic oncology

authors： Taylor DD,Gercel-Taylor C

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVE:The efficacy and toxicity of neoadjuvant chemotherapy (NAC) with mitomycin-C, vincristine and cisplatin (MVC) were assessed in bulky cervical carcinoma patients. METHODS:Forty-six patients with stage IB2 to IIB cervical cancer were treated with intravenous combination of mitomycin-C 10 mg/m(2), vincristine 1...

journal_title：Gynecologic oncology

authors： Choi CH,Kim TJ,Lee JW,Kim BG,Lee JH,Bae DS

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVES:Several predictive factors for lymph node spread in endometrial cancer have been identified including tumor grade, depth of invasion, lymphatic or vascular-space invasion, and histologic subtype. Lower uterine segment involvement may also be predictive of lymph node spread. The objective of this study was to...

journal_title：Gynecologic oncology

authors： Madom LM,Brown AK,Lui F,Moore RG,Granai CO,Disilvestro PA

更新日期：2007-10-01 00:00:00

abstract：:Choriocarcinoma cells grown in the presence of methotrexate (MTX) developed resistance in two ways. HCCM-derived sublines (relatively high MTX resistance) produced enhanced levels of dihydrofolate reductase (DHFR) and had impaired transport of MTX. Altered transport was the primary determinant of response in CC1-deriv...

journal_title：Gynecologic oncology

authors： Sakai K,Wake N,Fujino T,Yasuda T,Kato H,Fujimoto S,Fujinaga K

更新日期：1989-07-01 00:00:00

abstract：OBJECTIVE:UPSC is similar to papillary serous ovarian carcinoma in its histology and pattern of spread. The survival advantage with optimal debulking for ovarian cancer has been demonstrated. We examined our experience with UPSC. METHODS:Seventy-eight UPSC patients were seen between 1995 and 2008 at Rush University Me...

journal_title：Gynecologic oncology

authors： Patsavas K,Woessner J,Gielda B,Rotmensch J,Yordan E,Bitterman P,Guirguis A

更新日期：2011-06-01 00:00:00

abstract：:The usefulness of fine needle sampling (FNS) under transvaginal ultrasound guidance in gynecologic oncology patients is evaluated in this study. Between 1990 and 1993, 101 FNS under transvaginal ultrasound guidance were performed in 88 sessions. All targets were located deep in the pelvis and their median diameter was...

journal_title：Gynecologic oncology

authors： Zanetta G,Brenna A,Pittelli M,Lissoni A,Trio D,Riotta S

更新日期：1994-07-01 00:00:00

abstract：OBJECTIVE:Serum vascular endothelial growth factor (VEGF) levels have been shown to be associated with an adverse outcome in patients with ovarian cancer. We studied the clinical value of serum VEGF as an independent prognostic parameter. METHODS:In the present study, we ascertained preoperative serum VEGF in a series...

journal_title：Gynecologic oncology

authors： Hefler LA,Zeillinger R,Grimm C,Sood AK,Cheng WF,Gadducci A,Tempfer CB,Reinthaller A

更新日期：2006-11-01 00:00:00

abstract：:Human papillomavirus (HPV) has been implicated in the development of cervical cancer. Newly developed molecular techniques have facilitated HPV identification and typing of cervical lesions. Several studies have suggested a strong correlation between HPV16 and intraepithelial cervical neoplasia. However, there is no a...

journal_title：Gynecologic oncology

authors： Pasetto N,Sesti F,De Santis L,Piccione E,Novelli G,Dallapiccola B

更新日期：1992-07-01 00:00:00

abstract：OBJECTIVE:Upper abdominal spreading of advanced-stage ovarian cancer often involves the diaphragm. In addition, bulky diaphragmatic tumors occasionally infiltrate the liver. Here, we describe our early experiences with a ventral liver mobilization technique to remove diaphragmatic tumors with liver involvement. METHOD...

journal_title：Gynecologic oncology

authors： Kato K,Katsuda T,Takeshima N

更新日期：2016-03-01 00:00:00

abstract：:Ovarian carcinoma usually presents in an indolent manner, most often nonspecifically with complaints of abdominal pain or swelling, bloating, constipation, anorexia, early satiety, and evidence of ascites. We present a case of ovarian cancer with a cerebrovascular accident (CVA) as the presenting symptom, with minimal...

journal_title：Gynecologic oncology

authors： Shamonki MI,Squatrito RC,Welander CE

更新日期：1998-08-01 00:00:00

abstract：OBJECTIVE:To evaluate the contribution of molecular subtype to 30-day postoperative complications and 90-day mortality after primary debulking surgery (PDS) in advanced stage high-grade serous ovarian cancer (HGSOC). METHODS:Patients with stages III-IV HGSOC undergoing PDS from 1994 to 2011 with available molecular su...

journal_title：Gynecologic oncology

authors： Torres D,Kumar A,Bakkum-Gamez JN,Weaver AL,McGree ME,Wang C,Langstraat CL,Cliby WA

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Cases of malignant ovarian tumor composed of müllerian-type epithelial tumor and malignant germ cell tumor are extremely rare. CASE:We herein report the case of a 34-year-old woman with an ovarian tumor which was composed of endometrioid adenocarcinoma (EAC), clear cell adenocarcinoma (CCC), squamous cell c...

journal_title：Gynecologic oncology

authors： Ohishi Y,Kaku T,Kaneki E,Wake N,Tsuneyoshi M

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVE:To determine whether intra-operative radiation therapy (IORT) at the time of pelvic exenteration (PE) or laterally extended endopelvic resection (LEER) improves progression-free survival (PFS) in patients with recurrent, previously irradiated gynecologic cancers. METHODS:We conducted a single institution ret...

journal_title：Gynecologic oncology

authors： Backes FJ,Billingsley CC,Martin DD,Tierney BJ,Eisenhauer EL,Cohn DE,O'Malley DM,Salani R,Copeland LJ,Fowler JM

更新日期：2014-10-01 00:00:00

abstract：:The effect of two beta-adrenergic stimulating agents on bladder and urethral function was assessed in 16 patients 3 weeks after radical hysterectomy for carcinoma of the cervix. Urodynamic evaluation was performed before and after inhalation of metaproterenol by metered dose inhaler in 10 patients and injection of 0.2...

journal_title：Gynecologic oncology

authors： Kerr-Wilson RH,Orr JW Jr,Shingleton HM,Hatch KD,Trammel MW

更新日期：1986-03-01 00:00:00

abstract：OBJECTIVE:This article critically reviews the literature on the association between endometriosis and gynecological cancers and breast cancer, based on epidemiologic data. METHODS:Literature review of the English language literature based on searching in the MEDLINE (PubMed) database and additional collection of repor...

journal_title：Gynecologic oncology

authors： Munksgaard PS,Blaakaer J

更新日期：2011-10-01 00:00:00

abstract：:Adriamycin (50 mg/m2) and cis-diamminedichloroplatinum (50 mg/m2) were administered every 21 days to treat metastatic endometrial adenocarcinoma. This regimen resulted in three responses (one complete and two partial) in nine women (33%). Most patients had moderate or severe hematologic and gastrointestinal toxicity. ...

journal_title：Gynecologic oncology

authors： Seltzer V,Vogl SE,Kaplan BH

更新日期：1984-11-01 00:00:00

abstract：:Twelve patients with recurrent squamous cell carcinoma of the cervix restricted to the pelvis were treated with intra-arterial infusion of carboplatin. The initial carboplatin dose was 300 mg/m2, every 4 weeks, and the dose was escalated to 450 mg/m2. Myelosuppression was the dose-limiting toxicity at the 450 mg/m2 do...

journal_title：Gynecologic oncology

authors： Verma S,Prefontaine M,Bertrand M,Genest P,Dahrouge S

更新日期：1994-06-01 00:00:00

abstract：:Lymph node sampling is part of the FIGO staging of patients with ovarian carcinoma and is usually part of a meticulous second look operation. We analyzed the primary lymph node status of patients and compared this to the lymph node status at second look operation. From 3/86-3/91, 97 patients with epithelial ovarian tu...

journal_title：Gynecologic oncology

authors： Goldberg GL,Scheiner J,Friedman A,O'Hanlan KA,Davidson SA,Runowicz CD

更新日期：1992-11-01 00:00:00

abstract：OBJECTIVE:To examine the influence of diabetes and metformin therapy on overall survival (OS) and progression-free survival (PFS) in patients with endometrial cancer (EC) by using propensity score (PS) matching to account for confounding factors. METHODS:We retrospectively identified consecutive patients with stage I-...

journal_title：Gynecologic oncology

authors： Al Hilli MM,Bakkum-Gamez JN,Mariani A,Cliby WA,Mc Gree ME,Weaver AL,Dowdy SC,Podratz KC

更新日期：2016-02-01 00:00:00

abstract：OBJECTIVE:This study describes the surgical treatment and follow-up of 213 patients with primary vulvar cancer; particular attention is given to reconstructive surgical procedures. METHODS:The clinical and pathological parameters of the patients were recorded according to standardized procedures, and the data concerni...

journal_title：Gynecologic oncology

authors： Weikel W,Hofmann M,Steiner E,Knapstein PG,Koelbl H

更新日期：2005-10-01 00:00:00

abstract：:Malignant lipoid cell tumors of the ovary are rare lesions that are frequently associated with endocrinologic abnormalities. A case of a woman with this lesion who developed Cushing's syndrome with progression of tumor is presented. Neither aggressive medical therapy with ketoconazole nor multiagent chemotherapy was b...

journal_title：Gynecologic oncology

authors： Donovan JT,Otis CN,Powell JL,Cathcart HK

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND:Tumor lysis syndrome (TLS) is characterized by biochemical changes such as hyperuricemia and hyperkalemia due to rapid tumor lysis of malignant cells, usually after chemotherapy. TLS is a rare complication in nonhematological malignancies. CASE:A 53-year-old female received intravenous weekly paclitaxel for...

journal_title：Gynecologic oncology

authors： Yahata T,Nishikawa N,Aoki Y,Tanaka K

更新日期：2006-11-01 00:00:00

abstract：OBJECTIVE:Although the epidemiology of typical endometrial carcinomas (grades 1-2 endometrioid or Type I) is well established, less is known regarding higher grade endometrioid or non-endometrioid carcinomas (Type II). Within a large Gynecologic Oncology Group trial (GOG-210), which included central pathology review, w...

journal_title：Gynecologic oncology

authors： Brinton LA,Felix AS,McMeekin DS,Creasman WT,Sherman ME,Mutch D,Cohn DE,Walker JL,Moore RG,Downs LS,Soslow RA,Zaino R

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:The purpose of this work was to evaluate the ability of testing for high-risk human papillomavirus (HPV) types using the hybrid capture technique to predict the presence of cervical intraepithelial neoplasia (CIN) II,III in patients with repeated atypical squamous cells of undetermined significance (ASCUS) an...

journal_title：Gynecologic oncology

authors： Fait G,Kupferminc MJ,Daniel Y,Geva E,Ron IG,Lessing JB,Bar-Am A

更新日期：2000-11-01 00:00:00

abstract：OBJECTIVE:The aim of this trial was to investigate the efficacy and toxicity of a relative high-dose of topotecan combined with carboplatin in recurrent or persistent epithelial ovarian cancer (EOC). METHODS:Patients participating in this phase II trial received topotecan at a dose of 1.0 mg/m(2)/day intravenously (IV...

journal_title：Gynecologic oncology

authors： Kang H,Kim TJ,Lee YY,Choi CH,Lee JW,Bae DS,Kim BG

更新日期：2009-08-01 00:00:00

abstract：:Placement of a radiation implant in patients with cervical cancer may be difficult because of distortion of the canal by tumor or fibrosis from previous radiation. The objective of this study was to determine whether ultrasound may be useful in recognizing or preventing complications associated with placement of an in...

journal_title：Gynecologic oncology

authors： Rotmensch J,Waggoner SE,Quiet C

更新日期：1994-08-01 00:00:00

abstract：OBJECTIVES:To determine the impact of venous thromboembolism (VTE) during primary treatment of ovarian clear cell carcinoma (OCCC) on survival. METHODS:After Institutional Review Board approval, 74 cases of OCCC were retrieved from our pathology files. Clinical and pathological data were obtained by medical record and...

journal_title：Gynecologic oncology

authors： Diaz ES,Walts AE,Karlan BY,Walsh CS

更新日期：2013-12-01 00:00:00