Vulvar intraepithelial neoplasia in women infected with human immunodeficiency virus-1.

Abstract:

:The purpose of this study was to determine the response of vulvar intraepithelial neoplasia (VIN) lesions to standard treatment methods in women infected with human immunodeficiency virus (HIV). We reviewed all cases of VIN over a 4-year period at an inner-city hospital. We reviewed the clinical records of these women to abstract demographic information as well as information about tobacco use, injection drug use, results of HIV testing, T cell count, stage of HIV infection, colposcopic and cytologic findings, treatment of lesions, and follow-up. Eight of the 28 women (29%) with VIN were infected with HIV. The relative risk for recurrence or persistence of VIN after treatment was 3.3 (95% confidence interval, 1.4-7.4; P = 0.01) in the HIV+ compared with the HIV- group. The high rate of HIV infection among women with VIN supports recommendation of HIV testing for women with VIN. Women known to have HIV infection should be carefully examined for vulvar lesions. Further study is needed to determine the optimum treatment for VIN in women infected with HIV.

journal_name

Gynecol Oncol

journal_title

Gynecologic oncology

authors

Korn AP,Abercrombie PD,Foster A

doi

10.1006/gyno.1996.0161

subject

Has Abstract

pub_date

1996-06-01 00:00:00

pages

384-6

issue

3

eissn

0090-8258

issn

1095-6859

pii

S0090-8258(96)90161-4

journal_volume

61

pub_type

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