Current techniques in screening for cervical cancer in Spain: updated recommendations.

Abstract:

:A population-based survey (AFRODITA Study) was conducted in Spain in order to estimate the coverage and factors associated with cervical cancer cytological screening. The results of this survey indicate that the rate of screening for cervical cancer in Spain is 75.6% in women between 18 and 65 years. This high rate of opportunistic cervical cancer screening possibly has increased in the last 5 years. However, screening participation still needs to be improved in older women, women living in rural areas, women at a low socioeconomic level, and women living in certain autonomous regions. Conversely, an overuse of cytology has been observed in Spain, as a result of opportunistic screening. A survey in 2005, carried out in 14 public and private Spanish cytological laboratories, showed that among 409,443 women, the mean rate of abnormal cytology (a diagnosis of at least atypical cells of undetermined significance on a Pap smear) was 3.5% with a range of 0.5%-7.0% in Spain. We believe that this low rate of abnormal Pap smears is the result of repeated annual opportunistic screening in a low-risk population of women. A new Spanish consensus protocol for screening for cervical carcinoma was developed in 2006 by the Spanish Society of Gynaecology and Obstetrics, the Spanish Association of Cervical Pathology and Colposcopy, the Spanish Society of Cytology, and the Spanish Society of Anatomic Pathology. In order to rationalize the use of cervical cancer screening in Spain, the recommendations of the new Spanish consensus screening protocol must be followed.

journal_name

Gynecol Oncol

journal_title

Gynecologic oncology

authors

Puig-Tintoré LM,Torné A,Alonso I

doi

10.1016/j.ygyno.2008.05.013

subject

Has Abstract

pub_date

2008-09-01 00:00:00

pages

S8-S10

issue

3 Suppl 2

eissn

0090-8258

issn

1095-6859

pii

S0090-8258(08)00381-8

journal_volume

110

pub_type

杂志文章
  • Treatment of high-risk gestational trophoblastic neoplasia with weekly high-dose methotrexate-etoposide.

    abstract:OBJECTIVE:To assess toxicity and efficacy of weekly high-dose methotrexate-etoposide (HD MTX-ETO) in high-risk gestational trophoblastic neoplasia (GTN). METHODS:Retrospective chart review of high-risk GTN patients treated with HD MTX-ETO (methotrexate 1000 mg/m² day 1, etoposide 100 mg/m² days 1 and 2, q 1 wk). RESU...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2012.06.014

    authors: Han SN,Amant F,Leunen K,Devi UK,Neven P,Berteloot P,Vergote I

    更新日期:2012-10-01 00:00:00

  • Urinary tract dysfunction after radical hysterectomy for cervical cancer.

    abstract:OBJECTIVES:To evaluate the urinary tract dysfunction following a radical hysterectomy and to compare the baseline urodynamical parameters of women who had uterine cervical carcinoma with women who had CIN 3. METHODS:A prospective case-control study was conducted to evaluate preoperative and postoperative urinary tract...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1006/gyno.2002.6614

    authors: Chen GD,Lin LY,Wang PH,Lee HS

    更新日期:2002-05-01 00:00:00

  • Concurrent cisplatin and 5-fluorouracil chemotherapy and radiation therapy for advanced-stage squamous carcinoma of the vulva.

    abstract::A phase II trial of concurrent cisplatin and 5-fluorouracil (5-FU) chemotherapy and radiation therapy (CT + RT) was conducted for the primary treatment of 12 patients with retrospective surgical FIGO stages III-IV squamous carcinoma of the vulva. Eight patients were stage III and four were stage IV. Chemotherapy was u...

    journal_title:Gynecologic oncology

    pub_type: 临床试验,杂志文章

    doi:10.1016/0090-8258(91)90345-6

    authors: Berek JS,Heaps JM,Fu YS,Juillard GJ,Hacker NF

    更新日期:1991-09-01 00:00:00

  • The cost-effectiveness of selective lymphadenectomy based on a preoperative prediction model in patients with endometrial cancer: insights from the US and Korean healthcare systems.

    abstract:OBJECTIVE:The aim of this study was to determine the cost-effectiveness of selective lymphadenectomy using a preoperative prediction model compared to routine lymphadenectomy for patients undergoing surgery for endometrial cancer in the US and Korea. METHODS:We used a modified Markov model to estimate clinical and eco...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2014.09.020

    authors: Lee JY,Cohn DE,Kim Y,Lee TJ,Barnett JC,Kim JW,Jeon YW,Kim K,Park SM,Kang S

    更新日期:2014-12-01 00:00:00

  • Preoperative radiation therapy in clinical stage II endometrial carcinoma.

    abstract::From 1980 to 1987, 30 patients with FIGO clinical Stage II carcinoma of the endometrium were treated with 5000 cGy preoperative pelvic radiation therapy at Thomas Jefferson University Hospital. Patients with gross cervical disease received additional intracavitary irradiation with a tandem and ovoids for a combined to...

    journal_title:Gynecologic oncology

    pub_type: 临床试验,杂志文章

    doi:10.1016/0090-8258(92)90281-m

    authors: Reisinger SA,Staros EB,Feld R,Mohiuddin M,Lewis GC

    更新日期:1992-05-01 00:00:00

  • Preoperative hysteroscopic assessment of cervical invasion by endometrial carcinoma: a retrospective study.

    abstract:OBJECTIVE:The aim of this study was to evaluate the efficacy of hysteroscopy, using normal saline (NS) or carbon dioxide (CO2) as the distention medium, in assessing tumor invasion of the uterine cervix by endometrial carcinoma. METHODS:A retrospective study was conducted in 200 consecutive patients with endometrial c...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1006/gyno.2001.6270

    authors: Lo KW,Cheung TH,Yim SF,Chung TK

    更新日期:2001-08-01 00:00:00

  • Treatment of intraperitoneal metastatic adenocarcinoma of the endometrium by the whole-abdomen moving-strip technique and pelvic boost irradiation.

    abstract::Between October 1961, and November 1978, 31 patients with intraperitoneal metastatic adenocarcinoma of the endometrium were treated by whole-abdomen moving-strip technique and pelvic boost irradiation. In 27 patients, with residual disease less than or equal to 2 cm, the corrected 5-year survival rate was 80%. The abs...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/0090-8258(83)90164-6

    authors: Greer BE,Hamberger AD

    更新日期:1983-12-01 00:00:00

  • Skin relapse from cervical cancer.

    abstract:BACKGROUND:Cutaneous lymphangitis carcinomatosis from cervical carcinoma is a very rare form of tumor metastatization; only anecdotal cases are reported in the literature. Most of the patients with skin relapse experienced metastasis as a single or multiple nodules. CASE:A case of cutaneous lymphangitis carcinomatosis...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1006/gyno.2002.6808

    authors: Palaia I,Angioli R,Cutillo G,Manci N,Panici PB

    更新日期:2002-10-01 00:00:00

  • The 72-kDa metalloproteinase immunostaining in cervical carcinoma: relationship with lymph nodal involvement.

    abstract:OBJECTIVE:In the present study we detected 72-kDa metalloproteinase expression in our series of early stage cervical carcinomas and analyzed the relationship between 72-kDa metalloproteinase staining and risk of nodal involvement with the goal of identifying a parameter useful in predicting the metastatic potential of ...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1006/gyno.1996.0037

    authors: Garzetti GG,Ciavattini A,Lucarini G,Goteri G,Romanini C,Biagini G

    更新日期:1996-02-01 00:00:00

  • Prognostic value of metabolic tumor volume measured by FDG-PET/CT in patients with cervical cancer.

    abstract:OBJECTIVE:To determine if preoperative metabolic tumor volume (MTV) measured by integrated (18)F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (FDG-PET/CT) imaging has prognostic value in patients with cervical cancer treated primarily with radical hysterectomy. METHODS:Patients with FIGO s...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2010.11.002

    authors: Chung HH,Kim JW,Han KH,Eo JS,Kang KW,Park NH,Song YS,Chung JK,Kang SB

    更新日期:2011-02-01 00:00:00

  • Characterization of the protein synthesis independent TNFalpha lytic mechanism in human ovarian and cervical carcinoma cell lines.

    abstract::The analysis of the lytic mechanism initiated by TNFalpha in three human ovarian cell lines (CAOV-3, SK-OV-3, and OVCAR-3) and in three human cervical cell lines (SIHa, HT-3, and ME-180) in the presence of inhibitors of protein synthesis indicates that this lytic mechanism is similar to the protein synthesis-independe...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1006/gyno.1996.0187

    authors: Powell CB,Scott JH,Collins JL

    更新日期:1996-07-01 00:00:00

  • Limited utility of conventional criteria for predicting unresectable disease in patients with advanced stage epithelial ovarian cancer.

    abstract:OBJECTIVE:To evaluate the predictive value of conventional criteria for identifying surgically unresectable disease among patients with ovarian cancer undergoing initial operative intervention at tertiary referral centers employing a so-called aggressive approach to surgical cytoreduction. METHODS:All patients with ad...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2007.11.004

    authors: Salani R,Axtell A,Gerardi M,Holschneider C,Bristow RE

    更新日期:2008-02-01 00:00:00

  • Failure of hexamethylmelamine as salvage therapy in ovarian epithelial adenocarcinoma resistant to combination chemotherapy.

    abstract::Favorable responses to hexamethylmelamine (HMM) have been documented in untreated as well as in alkylating agent-resistant ovarian epithelial adenocarcinoma (OvCa). Platinum-based combination therapy for OvCa has been used since 1976. Eighteen patients with OvCa were treated with HMM as salvage therapy between Februar...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/0090-8258(84)90076-3

    authors: Stehman FB,Ehrlich CE,Callangan MF

    更新日期:1984-02-01 00:00:00

  • Neuropilin-1 promotes unlimited growth of ovarian cancer by evading contact inhibition.

    abstract:OBJECTIVE:Neuropilin-1 (NRP-1) is a receptor for both semaphorin and vascular endothelial growth factor and is up-regulated in a variety of human cancers. While there are some reports of NRP-1 expression in ovarian neoplasm, those results differ in pattern of its expression and its role in ovarian cancer is still uncle...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2007.02.005

    authors: Baba T,Kariya M,Higuchi T,Mandai M,Matsumura N,Kondoh E,Miyanishi M,Fukuhara K,Takakura K,Fujii S

    更新日期:2007-06-01 00:00:00

  • Toward understanding the natural history of ovarian carcinoma development: a clinicopathological approach.

    abstract:OBJECTIVE:The natural history of the development of ovarian carcinoma is not known. It also remains undetermined whether ovarian carcinomas develop from benign and/or borderline malignant tumors or arise de novo from the ovarian surface epithelium. METHODS:To address these issues clinicopathologically, we reviewed the...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/s0090-8258(02)00104-x

    authors: Horiuchi A,Itoh K,Shimizu M,Nakai I,Yamazaki T,Kimura K,Suzuki A,Shiozawa I,Ueda N,Konishi I

    更新日期:2003-03-01 00:00:00

  • Sustained complete remission in a patient with platinum-resistant ovarian yolk sac tumor.

    abstract:BACKGROUND:Yolk sac tumors of the ovary are generally very responsive to chemotherapy; however, they are difficult to manage in the setting of platinum resistance where treatment options are limited and outcomes are poorer. CASE:We present a 39-year-old woman who had a platinum-resistant yolk sac ovarian tumor. She ac...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1006/gyno.2001.6327

    authors: Jeyakumar A,Chalas E,Hindenburg A

    更新日期:2001-09-01 00:00:00

  • Malignant melanoma of the vulva: an extension of cutaneous melanoma?

    abstract:OBJECTIVE:To determine the prognostic significance of the 2002 revisions of the American Joint Committee on Cancer (AJCC) Staging System for cutaneous melanoma in melanoma of the vulva and review the current surgical utilized for treatment of this neoplasm. METHODS:Demographic, surgical and outcomes data were obtained...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2011.04.007

    authors: Moxley KM,Fader AN,Rose PG,Case AS,Mutch DG,Berry E,Schink JC,Kim CH,Chi DS,Moore KN

    更新日期:2011-09-01 00:00:00

  • Cloacogenic adenocarcinoma of the vulva.

    abstract::Primary adenocarcinoma of the vulva is rare, and cloagocenic adenocarcinoma of the vulva is extremely rare. Here we report a vulvar tumor characterized by columnar cells with prominent brush border and the presence of goblet cells and endocrine cells, presenting the tubulovillous pattern and mucin histochemistry of en...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1006/gyno.1999.5433

    authors: Willén R,Békássy,Carlén B,Bozoky B,Cajander S

    更新日期:1999-08-01 00:00:00

  • Human cervical cells immortalized in vitro with oncogenic human papillomavirus DNA differentiate dysplastically in vivo.

    abstract::Human papillomavirus (HPV) types 16 and 18 are associated with cervical dysplasia and carcinoma. In vitro integration of HPV-16 or HPV-18 DNA into cultured human cervical cells results in their immortalization. In this study, in vivo differentiation of human cervical cells immortalized with recombinant HPV-16 or HPV-1...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/0090-8258(90)90082-v

    authors: Waggoner SE,Woodworth CD,Stoler MH,Barnes WA,Delgado G,DiPaolo JA

    更新日期:1990-09-01 00:00:00

  • Risk assessment model for overall survival in patients with locally advanced cervical cancer treated with definitive concurrent chemoradiotherapy.

    abstract:OBJECTIVE:To develop a nomogram for predicting the probability of 5year survival after definitive concurrent chemoradiotherapy (CCRT) in locally advanced cervical cancer (LACC). METHODS:Between 1998 and 2008, 209 patients with LACC were treated with definitive CCRT. Multivariate analysis using Cox proportional hazards...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2012.09.033

    authors: Shim SH,Lee SW,Park JY,Kim YS,Kim DY,Kim JH,Kim YM,Kim YT,Nam JH

    更新日期:2013-01-01 00:00:00

  • Clinical and imaging findings in cervical cancer and their impact on FIGO and TNM staging - An analysis from the EMBRACE study.

    abstract:OBJECTIVE:To investigate differences in local tumour staging between clinical examination and MRI and differences between FIGO 2009, FIGO 2018 and TNM in patients with primary cervical cancer undergoing definitive radio-chemotherapy. METHODS:Patients from the prospective observational multi-centre study "EMBRACE" were...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2020.07.007

    authors: Knoth J,Pötter R,Jürgenliemk-Schulz IM,Haie-Meder C,Fokdal L,Sturdza A,Hoskin P,Mahantshetty U,Segedin B,Bruheim K,Wiebe E,Rai B,Cooper R,van der Steen-Banasik E,van Limbergen E,Pieters BR,Sundset M,Tan LT,Nout RA,T

    更新日期:2020-10-01 00:00:00

  • The accuracy of frozen section by tumor weight for ovarian epithelial neoplasms.

    abstract::This study evaluated the effect ovarian weight has on the accuracy of frozen sections in serous and mucinous ovarian tumors. The study group included 294 patients who had an initial frozen section (189 serous and 105 mucinous tumors) at surgery. The pathology reports were separated into subgroups (benign, borderline, ...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1006/gyno.1997.4836

    authors: Puls L,Heidtman E,Hunter JE,Crane M,Stafford J

    更新日期:1997-10-01 00:00:00

  • Uterine sarcoma occurring in a premenopausal patient after uterine artery embolization: a case report and review of the literature.

    abstract:OBJECTIVE:We report a case of uterine leiomyosarcoma occurring after uterine artery embolization and review the previously published cases. We estimate the incidence of sarcoma after UAE, the mean diagnostic delay in young women undergoing this procedure and review the potential and limits of preoperative procedures in...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2006.08.051

    authors: Papadia A,Salom EM,Fulcheri E,Ragni N

    更新日期:2007-01-01 00:00:00

  • The prognostic significance of surgical staging for carcinoma of the endometrium.

    abstract::This study is based on a retrospective review of 156 patients with endometrial carcinoma from 1978 through 1984 who underwent primary surgical evaluation. All cases were retrospectively restaged using the newly adopted FIGO surgical staging. The preoperative FIGO clinical stage distribution for this study was as follo...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/0090-8258(92)90276-o

    authors: Wolfson AH,Sightler SE,Markoe AM,Schwade JG,Averette HE,Ganjei P,Hilsenbeck SG

    更新日期:1992-05-01 00:00:00

  • A randomized study of the effectiveness of a brief psychosocial intervention for women attending a gynecologic cancer clinic.

    abstract:OBJECTIVES:While there are many psychosocial interventions for cancer patients, few are brief in nature. The aim of this study was to investigate the usefulness of a single-visit psychosocial intervention for gynecologic cancer patients. METHODS:One hundred women attending a gynecologic cancer clinic as new patients w...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.ygyno.2008.06.024

    authors: Powell CB,Kneier A,Chen LM,Rubin M,Kronewetter C,Levine E

    更新日期:2008-10-01 00:00:00

  • Strategies in late stage cervix carcinoma.

    abstract::Stage IIB-IV squamous cell carcinoma of the cervix when treated by irradiation has a significant failure rate. Causes of pelvic and distant failure are discussed. New techniques employed to improve local control and decrease distant metastasis are presented. Data on morbidity, mortality, and survival will be reviewed ...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/0090-8258(86)90135-6

    authors: Krochak R

    更新日期:1986-03-01 00:00:00

  • A case of microglandular adenocarcinoma of the endometrium.

    abstract:BACKGROUND:Microglandular adenocarcinoma is a rare type of endometrium carcinoma and had some potential diagnostic problems with difficulties in discriminating from some malign and benign lesions of cervix. CASE REPORT:A 70-year-old woman misdiagnosed as cervical adenocarcinoma was referred to our clinic, and the lesi...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2005.08.009

    authors: Karateke A,Haliloglu B,Atay V,Gurbuz A,Kir G

    更新日期:2005-12-01 00:00:00

  • Gestational trophoblastic diseases: 1. Pathophysiology of hyperglycosylated hCG.

    abstract:OBJECTIVE:Hyperglycosylated hCG (hCG-H) is a glycosylation variant of hCG produced by cytotrophoblast cells at implantation of pregnancy and in choriocarcinoma. We investigated the biological function of hCG-H in invasion in vitro and in vivo and the use of hCG-H antibodies in blocking tumorigenesis and cancer growth i...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2005.12.047

    authors: Cole LA,Dai D,Butler SA,Leslie KK,Kohorn EI

    更新日期:2006-08-01 00:00:00

  • Recurrence rate after loop electrosurgical excision procedure (LEEP) and laser Conization: A 5-year follow-up study.

    abstract:OBJECTIVE:Conization aims to remove pre-neoplastic lesions of the uterine cervix. Several techniques for conization have been compared, but evidence regarding the most effective therapeutic option is scant. Here, we aimed to compare the recurrence rate following laser conization and loop electrosurgical excision proced...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2020.08.025

    authors: Bogani G,DI Donato V,Sopracordevole F,Ciavattini A,Ghelardi A,Lopez S,Simoncini T,Plotti F,Casarin J,Serati M,Pinelli C,Valenti G,Bergamini A,Gardella B,Dell'acqua A,Monti E,Vercellini P,Fischetti M,D'Ippolito G,Agu

    更新日期:2020-12-01 00:00:00

  • Early invasive carcinoma of the cervix.

    abstract::Ninety-two patients with early invasive carcinoma of the cervix (5 mm or less) treated between July 1977 and June 1990 are reviewed. Eighty patients had squamous cell carcinomas and 12 had adenocarcinomas. The diagnosis was established by conization in 77 of 92 (83.6%) patients. Thirty-six patients (39%) had a depth o...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1006/gyno.1993.1241

    authors: Jones WB,Mercer GO,Lewis JL Jr,Rubin SC,Hoskins WJ

    更新日期:1993-10-01 00:00:00