New classification of ELPAT for living organ donation.

abstract：BACKGROUND:Previously, we identified an antimitogenic IgG antibody separated from sera of patients with known kidney transplant chronic rejection. This antibody inhibits individual patients' own unprimed T helper cell responses to alloantigens as well as a third-party mixed lymphocyte response, but does not inhibit aut...

journal_title：Transplantation

authors： Shoker AS,Okasha K,Sheridan DP,Kappel JE,Baltzan MA

更新日期：1997-09-27 00:00:00

abstract：BACKGROUND:Early allograft dysfunction (EAD) defined by serum total bilirubin (TB) of 10 mg/dL or greater or prothrombin time-international normalized ratio (PT-INR) of 1.6 or greater on postoperative day 7 (POD 7) or aminotransferase greater than 2000 IU/L within the first week, is associated with early graft loss aft...

journal_title：Transplantation

authors： Okamura Y,Yagi S,Sato T,Hata K,Ogawa E,Yoshizawa A,Kamo N,Yamashiki N,Okajima H,Kaido T,Uemoto S

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Membrane CD30 is an important costimulatory molecule for activated T lymphocytes, and serum level of soluble CD30 (sCD30) is considered a marker for predicting outcome in kidney transplantation. METHODS:We investigated the kinetics of CD30 expression on CD4 and CD8 T-cell populations and the source of sCD30...

journal_title：Transplantation

authors： Velásquez SY,García LF,Opelz G,Alvarez CM,Süsal C

更新日期：2013-07-27 00:00:00

abstract：:To determine the importance of static lung inflation during storage, graft performance was evaluated at different levels of intratracheal pressure and varying ischemic intervals. Lewis rat lungs were perfused with low-potassium Euro-Collins and stored for 4 or 8 hr either in atelectasis (4 hr: group I; 8 hr: group IV,...

journal_title：Transplantation

authors： Hausen B,Ramsamooj R,Hewitt CW,Schroder F,Beuke M,Poets CF,Schafers HJ

更新日期：1996-12-27 00:00:00

abstract：BACKGROUND:Epitopes are the sites to which antibodies bind. Both alpha and beta peptide chains of the human leukocyte antigen-DQ heterodimers (DQA1 and DQB1, respectively) contain polymorphic regions. We can identify DQA1 and DQB1 epitopes by DQ single antigen beads assay of the antibodies, correlating the beads' react...

journal_title：Transplantation

authors： Deng CT,El-Awar N,Ozawa M,Cai J,Lachmann N,Terasaki PI

更新日期：2008-08-15 00:00:00

abstract：BACKGROUND:Extended partial hepatectomy (PH) in patients is leading to portal hyperperfusion but reduced hepatic arterial perfusion (HAP), and is invariably causing focal hepatic venous outflow obstruction (FHVOO). We observed in a rat model that PH in combination with right median hepatic vein ligation (RMHV-L) caused...

journal_title：Transplantation

authors： Huang H,Deng M,Jin H,Liu A,Dahmen U,Dirsch O

更新日期：2014-05-27 00:00:00

abstract：BACKGROUND:Transplant recipients who develop COVID-19 may be at increased risk for morbidity and mortality. Determining the status of antibodies against SARS-CoV-2 in both candidates and recipients will be important to understand the epidemiology and clinical course of COVID-19 in this population. While there are multi...

journal_title：Transplantation

authors： Bray RA,Lee JH,Brescia P,Kumar D,Nong T,Shih R,Woodle ES,Maltzman JS,Gebel HM

更新日期：2021-01-01 00:00:00

abstract：:The humanization of animals is a powerful tool for the exploration of human disease pathogenesis in biomedical research, as well as for the development of therapeutic interventions with enhanced translational potential. Humanized models enable us to overcome biologic differences that exist between humans and other spe...

journal_title：Transplantation

authors： Adigbli G,Ménoret S,Cross AR,Hester J,Issa F,Anegon I

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:The objective of this study was to investigate purine nucleotide metabolism in peripheral blood mononuclear cells (PBMC) of cardiac transplant recipients switched from azathioprine to mycophenolate mofetil (MMF). METHODS:Concentrations of guanosine 5'triphosphate (GTP) and adenosine 5'triphosphate (ATP), th...

journal_title：Transplantation

authors： Devyatko E,Zuckermann A,Bohdjalian A,Roedler S,Dunkler D,Grimm M,Weigel G

更新日期：2006-07-15 00:00:00

abstract：BACKGROUND:Increasing clinical evidence suggests that delayed initial function secondary to ischemia/reperfusion injury alone, and particularly in combination with early episodes of acute rejection, reduces kidney allograft survival over time. METHODS:We investigated changes developing over the long term following a s...

journal_title：Transplantation

authors： Takada M,Nadeau KC,Shaw GD,Tilney NL

更新日期：1997-12-15 00:00:00

abstract：:To determine if cold preservation time continues to affect renal transplant outcome, prospectively collected data from 17,937 cadaveric renal transplants performed between 1982 and 1991 were analyzed. Cold preservation intervals of 1-16, 16-32, 32-48, and greater than 48 hr were studied by multi- and univariate method...

journal_title：Transplantation

authors： Peters TG,Shaver TR,Ames JE 4th,Santiago-Delpin EA,Jones KW,Blanton JW

更新日期：1995-01-27 00:00:00

abstract：:Spodoptera frugiperda (Sf9) insect cells secreted a class I MHC RT1.Aa heavy chain protein when infected with baculovirus that bore a construct that contained a honeybee melittin secretion (ms) signal attached to RT1.Aa cDNA. The RT1.Aa heavy chain protein in the culture supernatant and cell lysate immunoprecipitated ...

journal_title：Transplantation

authors： Wang M,Stepkowski SM,Wang ME,Tian L,Qu X,Tu Y,He G,Kahan BD

更新日期：1996-02-15 00:00:00

abstract：BACKGROUND:In the present study we examined the effect of the timing of marrow infusion on engraftment in nonmyeloablatively conditioned mice. METHODS:B10 mice were conditioned with decreasing doses of total body irradiation (TBI) and reconstituted with bone marrow cells (BMCs) from major histocompatibility complex-di...

journal_title：Transplantation

authors： Xu H,Exner BG,Chilton PM,Tanner MK,Mueller YM,Rezzoug F,Ildstad ST

更新日期：2004-03-27 00:00:00

abstract：:Heterologous anti-immunoglobulin (AI) is a potent immunosuppressive agent which compares favorably to anti-thymocyte serum (ATS) in inhibiting E and EAC-rosette formation and diminishing the secondary antibody response to sheep erythrocytes and E. coli lipopolysaccharide. AI prolongs H-2 incompatible skin allograft su...

journal_title：Transplantation

authors： Constantian MB,Couser WG,French PJ,Davis RC

更新日期：1976-09-01 00:00:00

abstract：BACKGROUND:Graft coronary arteriosclerosis (GCA) is the major limiting factor for long-term survival after heart transplantation. In this study, we investigated the effect of Multiglycosidorum tripterygii (MT) on GCA and platelet-derived growth factor A (PDGF-A) mRNA expression of transplanted hearts. METHODS:Two grou...

journal_title：Transplantation

authors： Hachida M,Zhang XL,Lu H,Hoshi H,Koyanagi H

更新日期：1998-06-15 00:00:00

abstract：BACKGROUND:The delayed allograft rejection in C6-deficient PVG C6- rats compared with normal PVG rats has been attributed to the lack of alloantibody activation of the membrane attack complex of complement. As T cells alone have been shown to effect graft rejection, we examined T-cell responses in PVG C6- rats. METHOD...

journal_title：Transplantation

authors： Merten S,Chen JC,Ha H,Plain K,Boyd RA,Penny MJ,Leenaerts P,Hall BM

更新日期：1998-05-15 00:00:00

abstract：:Anti-CD3 monoclonal antibody (mAb) OKT3 is immunosuppressive, but causes severe adverse effects during the first administration ("first-dose reaction"). These adverse effects are presumably caused by cytokine release that results from T-cell activation. In vitro, T-cell activation by anti-CD3 mAb requires interaction ...

journal_title：Transplantation

authors： Tax WJ,Tamboer WP,Jacobs CW,Frenken LA,Koene RA

更新日期：1997-01-15 00:00:00

abstract：BACKGROUND:Prophylactic administration of anti-HBs intravenous immunoglobulins (IVIg) in hepatitis B infected-liver transplant patients protects against acute rejection. To explore the suitability of intravenous immunoglobulins (IVIg) as prophylaxis of acute rejection and graft-versus-host disease (GVHD) after allograf...

journal_title：Transplantation

authors： Tha-In T,Metselaar HJ,Tilanus HW,Boor PP,Mancham S,Kuipers EJ,de Man RA,Kwekkeboom J

更新日期：2006-06-27 00:00:00

abstract：:Heart transplantation is considered nowadays the gold standard in the therapy of chronic and terminal heart insufficiency. Primary organ failure after heart transplantation is a severe complication generally related to prolonged ischemia time, poor quality of the organ, or acute rejection. All these factors can potent...

journal_title：Transplantation

authors： Beiras-Fernandez A,Weis FC,Fuchs H,Meiser BM,Reichart B,Weis M

更新日期：2006-10-27 00:00:00

abstract：:Chronic kidney disease is common in patients with multiple myeloma. Historically, individuals with end-stage renal disease and multiple myeloma did poorly with renal transplantation due to higher mortality rates from the malignancy itself or associated comorbidities. However, over the past 2 decades, there have been s...

journal_title：Transplantation

authors： Huskey JL,Heilman RL,Khamash H,Fonseca R

更新日期：2018-12-01 00:00:00

abstract：:In vitro pretreatment of islets of Langerhans with deoxyguanosine (dGuo) has been shown to be effective for the prolongation of islet allograft survival in rats. [This study evaluates the effect of pretreatment of islets with dGuo transplanted into CsA-treated recipients.] Transplantation of dGuo-treated islets from W...

journal_title：Transplantation

authors： al-Abdullah IH,Kumar AM,al-Adnani MS,Abouna GM

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND:The number of living donor kidney transplantations increases steeply in Europeans, whereas the non-Europeans are dependent on deceased donor transplantations. We wondered whether a low attendance or a high decline of potential non-European donors could explain this difference. METHODS:This retrospective stu...

journal_title：Transplantation

authors： Roodnat JI,van de Wetering J,Zuidema W,van Noord MA,Kal-van Gestel JA,Ijzermans JN,Weimar W

更新日期：2010-05-27 00:00:00

abstract：:The monoclonal antibodies (MoAb) CR11-351 and KS1 are secreted by hybridomas generated with splenocytes from BALB/c mice immunized with the cultured human B lymphoid cells LG-2 (HLA-A2,A2,B27,B27). The 2 monoclonal antibodies immunoprecipitated components with a superimposable 2-dimensional gel electrophoretic profile...

journal_title：Transplantation

authors： Tsujisaki M,Sakaguchi K,Igarashi M,Richiardi P,Perosa F,Ferrone S

更新日期：1988-03-01 00:00:00

abstract：BACKGROUND:Avascular osteonecrosis (AVN) is a serious complication of allogeneic stem cell transplantation (SCT). Graft-versus-host disease and its treatment with steroids are the main risk factors; underlying diagnosis, age and gender are further risk factors. It has been speculated that low baseline bone mineral dens...

journal_title：Transplantation

authors： Schulte CM,Beelen DW

更新日期：2005-06-27 00:00:00

abstract：BACKGROUND:Liver transplantation (LT) represents a curative treatment for small hepatocellular carcinoma (HCC). Potentially curable higher-stage HCC patients are denied LT due to the lack of cancer markers that predict progression and recurrence. METHODS:Thirty-eight candidates for LT with hepatitis C virus (HCV) cirr...

journal_title：Transplantation

authors： Mas VR,Fisher RA,Archer KJ,Yanek KC,Williams B,Dumur CI,Maluf DG

更新日期：2007-04-15 00:00:00

abstract：:Among the first 52 recipients of primary liver allografts with follow-up of 2 weeks or greater, 6 patients had biopsy-confirmed vanishing bile duct syndrome (VBDS) and required retransplantation. Five of these six patients had positive lymphocyte crossmatches. Of the 46 remaining liver transplant recipients, 11 had po...

journal_title：Transplantation

authors： Batts KP,Moore SB,Perkins JD,Wiesner RH,Grambsch PM,Krom RA

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND:The role of changes in peri-operative blood lactate levels in recipients of living-related liver transplants has not yet been clarified. METHODS:Forty-three recipients were included in this study. Blood lactate, plasma total bilirubin, aminotransferase, body temperature, and gastric mucosal PCO2 levels were...

journal_title：Transplantation

authors： Orii R,Sugawara Y,Hayashida M,Yamada Y,Kubota K,Takayama T,Harihara Y,Makuuchi M,Hanaoka K

更新日期：2000-05-27 00:00:00

abstract：:Pretreatment of LEW rats with cyclosporin A (10 mg/kg/day orally for 14 days) plus 10(8) DA or (DA X LEW)F1 spleen lymphocytes on two occasions markedly prolonged the survival of subsequent DA renal allografts. The lymphocytotoxic antibody response was suppressed completely and renal biopsies showed a marked mononucle...

journal_title：Transplantation

authors： Homan WP,Williams KA,Millard PR,Morris PJ

更新日期：1981-06-01 00:00:00

abstract：:Despite the significant improvements that have occurred since the introduction of CsA, long-term renal allograft survival continues to be an area of concern. Management strategies that involve the use of sirolimus offer some promise. A number of observations suggest that sirolimus may have the ability to reduce the ra...

journal_title：Transplantation

authors： Kahan BD

更新日期：2001-06-15 00:00:00

abstract：BACKGROUND:The purpose of this study was to determine whether screening for anti-human leukocyte antigen (HLA) antibodies (Abs) could predict development of acute rejection (AR) before clinical evidence of kidney allograft dysfunction in nonsensitized recipients. METHODS:Eighty-four non-HLA identical kidney transplant...

journal_title：Transplantation

authors： Gill JS,Landsberg D,Johnston O,Shapiro RJ,Magil AB,Wu V,Tinckam K,Keown P

更新日期：2010-01-27 00:00:00