Squamous cell carcinoma of the oral tongue in patients over 75 years old.

Abstract:

BACKGROUND AND AIMS:Squamous cell carcinoma (SCC) of the oral tongue is one of the most frequent head and neck cancers. The over-70-year age group is the fastest growing segment of the population. Age, however, is not considered a prognostic factor in oral tongue SCC. This study investigated the clinical and histopathological characteristics, disease course, and outcome of SCC of the oral tongue in patients over 75 years old compared with younger patients. METHODS:We reviewed the files of 85 patients with histologically proven SCC of the oral tongue who were treated in our department in 1992-2007 and followed for a minimum of 2 years. Findings were compared between those aged 75 years or more and younger patients. RESULTS:Twenty-eight patients (33%) were aged 75 to 94 years (average 80.5±4.5 yrs), including 14 who were over 80 years old, and 57 patients were aged 15-74 years (average 51.1±18.2 yrs). No statistically significant differences were found between the groups in clinical or histopathological characteristics or patient outcome. The 5-year disease-free survival rate was 65% for patients over 75 and 58% for younger patients. Corresponding rates for 5-year disease-specific survival were 69% and 70%. These differences were not statistically significant. CONCLUSIONS:Patients over 75 with oral tongue SCC should be managed like younger patients in terms of clinical staging and co-morbidities. They should be given a chance for treatment, as their prognosis is no different from that of younger patients.

journal_name

Aging Clin Exp Res

authors

Soudry E,Preis M,Hod R,Hamzany Y,Hadar T,Bahar G,Sternov Y,Shpitzer T

doi

10.1007/BF03324964

subject

Has Abstract

pub_date

2011-06-01 00:00:00

pages

231-5

issue

3

eissn

1594-0667

issn

1720-8319

pii

8031

journal_volume

23

pub_type

杂志文章
  • Reduced gait and postural stability under challenging conditions in fallers with upper limb fracture.

    abstract:BACKGROUND:While most fractures are caused by falls, not all falls result in fractures. Risk factors for falls are well established, but only weak associations have been demonstrated for risk factors for fractures. Conflicting results on the implication of bone mineral density (BMD) suggest that other risk factors shou...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/s40520-018-0992-z

    authors: Langeard A,Pothier K,Chastan N,Marcelli C,Chavoix C,Bessot N

    更新日期:2019-04-01 00:00:00

  • The occurrence of acute myocardial infarction in Italy: a five-year analysis of hospital discharge records.

    abstract:BACKGROUND:The incidence and costs of acute myocardial infarction (AMI) in Europe represent a substantial problem due to population aging. METHODS:Between 2001 and 2005, Italian hospitalization records were examined to evaluate hospital admissions and costs of AMI in adults aged ≥ 45 and in elderly people ≥ 65 or ≥ 75...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/BF03337744

    authors: Piscitelli P,Iolascon G,Greco M,Marinelli A,Gimigliano F,Gimigliano R,Gisonni P,Giordano A,Migliore A,Granata M,Tarantino U,Brandi ML,Baggiani A,Distante A

    更新日期:2011-02-01 00:00:00

  • Incidence and prognostic significance of hypoglycemia in hospitalized non-diabetic elderly patients.

    abstract:BACKGROUND AND AIMS:To assess the incidence and prognostic value of hypoglycemia in hospitalized non-diabetic elderly patients. METHODS:An observational retrospective study, with a 3-year follow-up, was performed in a series of 678 patients aged over 65 years, admitted between January 1 2001 and December 31 2001 to th...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/BF03324842

    authors: Mannucci E,Monami M,Mannucci M,Chiasserini V,Nicoletti P,Gabbani L,Giglioli L,Masotti G,Marchionni N

    更新日期:2006-10-01 00:00:00

  • Role of functional performance in diagnosis of dementia in elderly people with low educational level living in Southern Italy.

    abstract:BACKGROUND AND AIMS:Diagnosis of dementia is often difficult in subjects with low educational level. Our aim was to evaluate the role of functional performance and the possibility of preferring scores of activities of daily living (ADL) and instrumental activities of daily living (IADL) in screening elderly people for ...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/BF03324675

    authors: Iavarone A,Milan G,Vargas G,Lamenza F,De Falco C,Gallotta G,Postiglione A

    更新日期:2007-04-01 00:00:00

  • Influence of training status and eNOS haplotypes on plasma nitrite concentrations in normotensive older adults: a hypothesis-generating study.

    abstract::The purpose of this study was to evaluate the relationship between 3 eNOS gene polymorphisms and training status (TS) in affecting plasma nitrite concentration (NO2) in normotensive adults over 50 years old. Resting blood pressure (BP) was measured in all participants (n = 101). Plasma was taken to analyze: lipid prof...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/s40520-014-0218-y

    authors: da Silva RF,Sertório JT,Lacchini R,Trapé AA,Tanus-Santos JE,Rush JW,Amaral SL,Zago AS

    更新日期:2014-12-01 00:00:00

  • Depression in the elderly: new concepts and therapeutic approaches.

    abstract::Depression is one of the leading causes of suffering in the elderly, but it is often under-diagnosed and under-treated, partly due to the false belief that depression is a common aspect of aging. Depression in the elderly is frequently comorbid with medical illnesses, may often be expressed by somatic complaints, and ...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章,评审

    doi:10.1007/BF03327382

    authors: Mecocci P,Cherubini A,Mariani E,Ruggiero C,Senin U

    更新日期:2004-06-01 00:00:00

  • Racial variations in self-reported osteoarthritis symptom severity among veterans.

    abstract:BACKGROUND AND AIMS:This study aimed at examining factors related to osteoarthritis (OA) symptom severity in African American and Caucasian veterans (n=202). METHODS:OA symptom severity (lower extremity pain, stiffness, and physical function) was measured by the Western Ontario and McMaster Universities Osteoarthritis...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/BF03324608

    authors: Golightly YM,Dominick KL

    更新日期:2005-08-01 00:00:00

  • Representativeness of the "Fiesole Misurata" study database for use in pharmaco-epidemiological investigations on adherence to antihypertensive medications.

    abstract:BACKGROUND AND AIMS:Poor adherence to medications is a major health concern especially among older subjects. To plan future studies to improve adherence, an epidemiological study, called "Fiesole Misurata", was conducted. The aim of the present paper was to verify the representativeness of the database in evaluating th...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/s40520-013-0060-7

    authors: Lapi F,Lucenteforte E,Moschini M,Bonaiuti R,Di Pirro M,Barchielli A,Benemei S,Belladonna M,Nesti N,Coppini R,Taras M,Vannacci A,Ungar A,Mugelli A

    更新日期:2013-08-01 00:00:00

  • Income differentials in functional disability in old age: relative risks of onset, recovery, decline, attrition and mortality.

    abstract:BACKGROUND AND AIMS:Socioeconomic status (SES) differences in health decline in late life may be underestimated, because the relatively higher risks of attrition of lower-SES persons are seldom taken into account. This longitudinal study aimed at comparing income differences in the course of disability, non-mortality a...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/BF03324497

    authors: Broese van Groenou MI,Deeg DJ,Penninx BW

    更新日期:2003-04-01 00:00:00

  • Nature diversity and well-being in old age.

    abstract:BACKGROUND:The research aim was to study the associations of nature diversity with quality of life (QoL) and depressive symptoms among older people, and whether physical activity explains the associations. METHODS:Community-dwelling people aged 75-90 years (n = 848) living in Central Finland were interviewed in their ...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/s40520-017-0797-5

    authors: Rantakokko M,Keskinen KE,Kokko K,Portegijs E

    更新日期:2018-05-01 00:00:00

  • Hypovitaminosis D is associated with a reduction in upper and lower limb muscle strength and physical performance in post-menopausal women: a retrospective study.

    abstract:BACKGROUND:Elderly people experience a gradual loss of muscle strength and a reduction of serum levels of vitamin D and of vitamin D receptor expression in skeletal muscle cells. AIMS:The aim of our study was to evaluate the association among serum levels of 25-hydroxy-vitamin D [25(OH)D3], muscle strength, and physic...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/s40520-015-0405-5

    authors: Iolascon G,de Sire A,Calafiore D,Moretti A,Gimigliano R,Gimigliano F

    更新日期:2015-10-01 00:00:00

  • Improved health among 70-year olds: comparison of health indicators in three different birth cohorts.

    abstract:BACKGROUND AND AIMS:Whether or not there has been a "compression of morbidity" in older ages has been vividly debated during the last decades. Previous studies have found indications of both improved and deteriorated health among elderly persons. Few studies have analyzed how changes in health indicators are influenced...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/BF03324463

    authors: Wilhelmson K,Allebeck P,Steen B

    更新日期:2002-10-01 00:00:00

  • Using the Multidimensional Prognostic Index (MPI) to improve cost-effectiveness of interventions in multimorbid frail older persons: results and final recommendations from the MPI_AGE European Project.

    abstract::MPI_AGE is a European Union co-funded research project aimed to use the Multidimensional Prognostic Index (MPI), a validated Comprehensive Geriatric Assessment (CGA)-based prognostic tool, to develop predictive rules that guide clinical and management decisions in older people in different European countries. A series...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章,评审

    doi:10.1007/s40520-020-01516-0

    authors: Cruz-Jentoft AJ,Daragjati J,Fratiglioni L,Maggi S,Mangoni AA,Mattace-Raso F,Paccalin M,Polidori MC,Topinkova E,Ferrucci L,Pilotto A,MPI_AGE Investigators.

    更新日期:2020-05-01 00:00:00

  • Minimizing comprehensive geriatric assessment to identify deterioration of physical performance in a healthy community-dwelling older cohort: longitudinal data of the AEQUIPA Versa study.

    abstract:BACKGROUND:It is important to identify the relevant parameters of physical performance to prevent early functional decline and to prolong independent living. The aim of this study is to describe the development of physical performance in a healthy community-dwelling older cohort aged 70+ years using comprehensive asses...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/s40520-020-01562-8

    authors: Diekmann R,Hellmers S,Elgert L,Fudickar S,Heinks A,Lau S,Bauer JM,Zieschang T,Hein A

    更新日期:2020-05-01 00:00:00

  • Executive function and life-space mobility in old age.

    abstract:BACKGROUND:Life-space assessment incorporates all movements in terms of the distance from home, the frequency of movement and the need of assistance for movement. Executive function (EF) is an important higher order cognitive ability that controls and guides people's goal-directed actions. We examined the cross-section...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/s40520-017-0762-3

    authors: Poranen-Clark T,von Bonsdorff MB,Rantakokko M,Portegijs E,Eronen J,Kauppinen M,Eriksson JG,Rantanen T,Viljanen A

    更新日期:2018-02-01 00:00:00

  • Monochromatic phototherapy: effective treatment for grade II chronic pressure ulcers in elderly patients.

    abstract:BACKGROUND AND AIMS:Monochromatic pulsating light may have effects on wound healing. In an earlier study of grade II ulcers, there was a tendency toward better healing in the phototherapy group (p=0.06). The present study on patients with grade II ulcers was performed to verify these findings. Data from this study were...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/BF03324734

    authors: Dehlin O,Elmståhl S,Gottrup F

    更新日期:2007-12-01 00:00:00

  • Effect of somatosensory and neurofeedback training on balance in older healthy adults: a preliminary investigation.

    abstract::The aim of this study was to assess the effectiveness of balance training with somatosensory and neurofeedback training on dynamic and static balance in healthy, elderly adults. The sample group consisted of 45 healthy adults randomly assigned to one of the three test groups: somatosensory, neurofeedback, and a contro...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s40520-017-0835-3

    authors: Azarpaikan A,Taheri Torbati H

    更新日期:2018-07-01 00:00:00

  • Validity of the interRAI Acute Care based on test content: a multi-center study.

    abstract:BACKGROUND AND AIMS:The MDS inter- RAI Acute Care is a comprehensive geriatric assessment tool for hospitalized older persons. The aim was to examine its validity based on test content by use in daily clinical practice. METHODS:Clinical staff of multiple disciplines assessed 256 older persons (83.2±5.2 years; 60% fema...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章,多中心研究

    doi:10.1007/BF03325244

    authors: Wellens NI,Deschodt M,Boonen S,Flamaing J,Gray L,Moons P,Milisen K

    更新日期:2011-10-01 00:00:00

  • Strength training and protein supplementation improve muscle mass, strength, and function in mobility-limited older adults: a randomized controlled trial.

    abstract:BACKGROUND:Adaptation to strength training in very old mobility-limited individuals is not fully characterized. Therefore, the aim of this study was to perform a thorough investigation of the adaptation to a lower body strength training regime in this population, with particular emphasis on the relationship between cha...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s40520-019-01234-2

    authors: Aas SN,Seynnes O,Benestad HB,Raastad T

    更新日期:2020-04-01 00:00:00

  • Stepping down backwards as a means of detecting biomechanical differences between healthy older and younger adults.

    abstract:BACKGROUND AND AIMS:Changes in sensory- motor systems that occur with age result in a decrease in postural equilibrium, which has been linked with an increased risk of falling in the elderly. Stepping down backwards from a step perturbs dynamic postural equilibrium, thus offering an opportunity to analyze the biomechan...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/BF03324776

    authors: Michel-Pellegrino V,Hewson D,Hogrel JY,Duchêne J

    更新日期:2008-06-01 00:00:00

  • Association with and predictive capacity of self-perceived risk of falling in recurrent falls in older people: a prospective study.

    abstract:OBJECTIVE:Given the impact of recurrent falls in older people, risk evaluation for falling is an important part of geriatric assessment. Available clinical tools usually do not include patients' self-perceived risk of falling. The objective of this study was to evaluate association with and predictive capacity of self-...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/s40520-013-0130-x

    authors: Gálvez-Barrón C,Sanguino MJ,Narvaiza L,Cavestany F,Collado I,Macho O,Dapena MD,Rodríguez-Molinero A

    更新日期:2013-10-01 00:00:00

  • Three-year National report from the Gruppo Italiano di Ortogeriatria (GIOG) in the management of hip-fractured patients.

    abstract:BACKGROUND:Hip fractures (HF) are a major issue worldwide. We aimed at evaluating the practices in delivering care to patients with HF among several Italian Orthogeriatric centers. METHODS:The study took place from February 2016 to July 2018. Seven performance indicators (pre-surgical cognitive assessment, surgery per...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/s40520-020-01488-1

    authors: Ferrara MC,Andreano A,Tassistro E,Rapazzini P,Zurlo A,Volpato S,Mussi C,Corsi M,Lunardelli ML,Martini E,Castoldi G,De Filippi F,Pizzonia M,Monacelli F,Barone A,Pilotto A,March A,Ungar A,Capelli R,Galmarini V,Franz

    更新日期:2020-07-01 00:00:00

  • Carotid plague formation is associated with ankle-brachial index in elderly people.

    abstract:AIMS:This study aimed at examining whether ankle-brachial index (ABI) and brachial-ankle pulse wave velocity (baPWV) were independently associated with carotid Intima-media thickness (CIMT) or carotid artery plaque (CAP) in elderly people. METHODS:A cross-sectional analysis was performed in 155 individuals aged over 7...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/s40520-019-01415-z

    authors: Pan FF,Xu CC,Hu TJ,Fu GX,Zhong Y

    更新日期:2020-11-01 00:00:00

  • Role of clinical frailty on long-term mortality of elderly subjects with and without chronic obstructive pulmonary disease.

    abstract:BACKGROUND AND AIMS:Elderly subjects are characterized by a high prevalence of chronic obstructive pulmonary disease (COPD) and frailty. This study examined the predictive role of frailty on long-term mortality in elderly subjects with and without COPD. METHODS:The study assessed mortality after a 12-year follow-up in...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/BF03351076

    authors: Galizia G,Cacciatore F,Testa G,Della-Morte D,Mazzella F,Langellotto A,Raucci C,Gargiulo G,Ferrara N,Rengo F,Abete P

    更新日期:2011-04-01 00:00:00

  • Validation of population-based cutoffs for low muscle mass and strength in a population of Turkish elderly adults.

    abstract:BACKGROUND:Despite differences between the studies regarding methods for estimating low muscle mass, the European Working Group on Sarcopenia in Older People (EWGSOP) recommends use of two standard deviations (SDs) below the reference sex-specific means of healthy young adults. AIMS:The aim of this study was to determ...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/s40520-019-01448-4

    authors: Ates Bulut E,Soysal P,Dokuzlar O,Kocyigit SE,Aydin AE,Yavuz I,Isik AT

    更新日期:2020-09-01 00:00:00

  • Neutrophil-to-lymphocyte count ratio is associated with perforated appendicitis in elderly patients of emergency department.

    abstract:PURPOSE:The diagnostic value of the neutrophil-to-lymphocyte count ratio (NLR) and the Appendicitis Inflammatory Response (AIR) score for identifying acute appendicitis (AA) perforation in elderly patients in the emergency department (ED) were evaluated. METHODS:A total of 103 patients who were admitted for appendecto...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/s40520-016-0584-8

    authors: Jung SK,Rhee DY,Lee WJ,Woo SH,Seol SH,Kim DH,Choi SP

    更新日期:2017-06-01 00:00:00

  • Circadian temporal organization of lipidic fractions in elderly people. Entrainment to the dietary schedule.

    abstract:BACKGROUND AND AIMS:Changes in some rhythmometric parameters have been reported in the elderly as a consequence of both structural and neurochemical changes occurring in the central nervous system. Since alterations of lipid and lipoprotein metabolism are directly involved in several age-related disorders, the aim of t...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/BF03324422

    authors: Trotti R,Rondanelli M,Cuzzoni G,Ferrari E,d'Eril GM

    更新日期:2002-04-01 00:00:00

  • Relationships between adiponectin and matrix metalloproteinase-9 (MMP-9) serum levels and postoperative cognitive dysfunction in elderly patients after general anesthesia.

    abstract:OBJECTIVE:The aim of this study was to evaluate the relationships between the serum levels of adiponectin (ADP) and matrix metalloproteinase-9 (MMP-9) and postoperative cognitive dysfunction (POCD) in elderly patients after general anesthesia. METHODS:The cognitive functions of 98 elderly patients who were scheduled t...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/s40520-015-0519-9

    authors: Xie H,Huang D,Zhang S,Hu X,Guo J,Wang Z,Zhou G

    更新日期:2016-12-01 00:00:00

  • Clinical assessment of gait and functional mobility in Italian healthy and cognitively impaired older persons using wearable inertial sensors.

    abstract:AIM:The main purpose of the present study was to verify the feasibility of wearable inertial sensors (IMUs) in a clinical setting to screen gait and functional mobility in Italian older persons. In particular, we intended to verify the capability of IMUs to discriminate individuals with and without cognitive impairment...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/s40520-020-01715-9

    authors: Mulas I,Putzu V,Asoni G,Viale D,Mameli I,Pau M

    更新日期:2020-09-25 00:00:00

  • Neural substrate of a cognitive intervention program using Go game: a positron emission tomography study.

    abstract:BACKGROUND:Influence of cognitive intervention programs on brain activity has not been enough explored. AIMS:The aims of the present study were to clarify changes in brain activity from a cognitive intervention program utilizing the board game "Go" and to examine the relationship between brain activity and the acquisi...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/s40520-019-01462-6

    authors: Iizuka A,Ishii K,Wagatsuma K,Ishibashi K,Onishi A,Tanaka M,Suzuki H,Awata S,Fujiwara Y

    更新日期:2020-11-01 00:00:00