Squamous cell carcinoma of the oral tongue in patients over 75 years old.


BACKGROUND AND AIMS:Squamous cell carcinoma (SCC) of the oral tongue is one of the most frequent head and neck cancers. The over-70-year age group is the fastest growing segment of the population. Age, however, is not considered a prognostic factor in oral tongue SCC. This study investigated the clinical and histopathological characteristics, disease course, and outcome of SCC of the oral tongue in patients over 75 years old compared with younger patients. METHODS:We reviewed the files of 85 patients with histologically proven SCC of the oral tongue who were treated in our department in 1992-2007 and followed for a minimum of 2 years. Findings were compared between those aged 75 years or more and younger patients. RESULTS:Twenty-eight patients (33%) were aged 75 to 94 years (average 80.5±4.5 yrs), including 14 who were over 80 years old, and 57 patients were aged 15-74 years (average 51.1±18.2 yrs). No statistically significant differences were found between the groups in clinical or histopathological characteristics or patient outcome. The 5-year disease-free survival rate was 65% for patients over 75 and 58% for younger patients. Corresponding rates for 5-year disease-specific survival were 69% and 70%. These differences were not statistically significant. CONCLUSIONS:Patients over 75 with oral tongue SCC should be managed like younger patients in terms of clinical staging and co-morbidities. They should be given a chance for treatment, as their prognosis is no different from that of younger patients.


Aging Clin Exp Res


Soudry E,Preis M,Hod R,Hamzany Y,Hadar T,Bahar G,Sternov Y,Shpitzer T




Has Abstract


2011-06-01 00:00:00














  • Latin American Adult Immunisation Advocacy Summit: Overcoming regional barriers to adult vaccination.

    abstract::Older adults in Latin America are at an increased risk of hospitalisation, ill health, catastrophic disability and death due to vaccine-preventable diseases such as influenza, herpes zoster, and pneumonia. The Latin American Adult Immunisation Advocacy Summit, held in Mexico City, gathered 40 experts in health, ageing...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Barratt J,Mishra V,Acton M

    更新日期:2019-03-01 00:00:00

  • Development of a Japanese version of the SARC-F for diabetic patients: an examination of reliability and validity.

    abstract:BACKGROUND:SARC-F is a 5-item, self-administered questionnaire developed to screen sarcopenia. To date, no Japanese version of the SARC-F has been developed. AIMS:To create a Japanese version of the SARC-F (SARC-F-J), a questionnaire for diabetic patients, and to investigate its reliability and validity. METHODS:This...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Ida S,Murata K,Nakadachi D,Ishihara Y,Imataka K,Uchida A,Monguchi K,Kaneko R,Fujiwara R,Takahashi H

    更新日期:2017-10-01 00:00:00

  • Functional status and satisfaction with community participation in persons with stroke following medical rehabilitation.

    abstract:BACKGROUND AND AIMS:Researchers and policy-makers have recognized that quality of life assessments are essential to better understand the benefits of rehabilitation intervention. The purpose of the study was to examine associations between functional status and satisfaction with community participation for persons with...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Ostir GV,Smith PM,Smith D,Ottenbacher KJ

    更新日期:2005-02-01 00:00:00

  • The Emergency Surgery Frailty Index (EmSFI): development and internal validation of a novel simple bedside risk score for elderly patients undergoing emergency surgery.

    abstract:BACKGROUND:Frailty assessment has acquired an increasing importance in recent years and it has been demonstrated that this vulnerable profile predisposes elderly patients to a worse outcome after surgery. Therefore, it becomes paramount to perform an accurate stratification of surgical risk in elderly undergoing emerge...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Costa G,Bersigotti L,Massa G,Lepre L,Fransvea P,Lucarini A,Mercantini P,Balducci G,Sganga G,Crucitti A,ERASO (Elderly Risk Assessment, Surgical Outcome) Collaborative Study Group.

    更新日期:2020-11-18 00:00:00

  • Arterial stiffness and the response to carotid sinus massage in older adults.

    abstract:BACKGROUND AND AIMS:Carotid sinus hypersensitivity (CSH) is a common cause of fainting and falls in the older adult population and is diagnosed by carotid sinus massage (CSM). Previous work has suggested that age-related stiffening of blood vessels reduces afferent input from the carotid sinus leading to central upregu...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Madden KM,Lockhart C,Khan K

    更新日期:2010-02-01 00:00:00

  • Alternative and complementary therapies in osteoarthritis and cartilage repair.

    abstract::Osteoarthritis (OA) is the most common joint condition and, with a burgeoning ageing population, is due to increase in prevalence. Beyond conventional medical and surgical interventions, there are an increasing number of 'alternative' therapies. These alternative therapies may have a limited evidence base and, for thi...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章,评审


    authors: Fuggle NR,Cooper C,Oreffo ROC,Price AJ,Kaux JF,Maheu E,Cutolo M,Honvo G,Conaghan PG,Berenbaum F,Branco J,Brandi ML,Cortet B,Veronese N,Kurth AA,Matijevic R,Roth R,Pelletier JP,Martel-Pelletier J,Vlaskovska M,Thoma

    更新日期:2020-04-01 00:00:00

  • Cervical joint position sense is impaired in older adults.

    abstract:BACKGROUND AND AIMS:Although the role of afferent input from cervical muscles on the control of posture and locomotion is recognised, it is surprising that there is an absence of data reporting whether joint position sense at the cervical level is impaired in older healthy adults. The present experiment was designed to...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Vuillerme N,Pinsault N,Bouvier B

    更新日期:2008-08-01 00:00:00

  • A combined stepping and visual tracking task predicts cognitive decline in older adults better than gait or visual tracking tasks alone: a prospective study.

    abstract:BACKGROUND:It is unclear whether motor-cognitive dual tasks predict cognitive decline better than either motor or cognitive tasks alone. AIMS:To examine the utility of the novel motor-cognitive dual-task test [Stepping Trail Making Test (S-TMT)], as a predictor of cognitive decline, and compare its predictive performa...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Osuka Y,Kim H,Watanabe Y,Taniguchi Y,Kojima N,Seino S,Kawai H,Sakurai R,Inagaki H,Awata S,Shinkai S

    更新日期:2020-09-23 00:00:00

  • Gender differences and burden of chronic conditions: impact on quality of life among the elderly in Taiwan.

    abstract:BACKGROUND:Multiple chronic conditions affect people's health-related quality of life (QoL) and the distributions of the conditions may differ between genders. Our goal was to examine gender differences in chronic conditions and QoL among community-living elderly in Taiwan and to examine whether differences in QoL betw...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Yu T,Enkh-Amgalan N,Zorigt G,Hsu YJ,Chen HJ,Yang HY

    更新日期:2019-11-01 00:00:00

  • Age-associated changes in hand grip and quadriceps muscle strength ratios in healthy adults.

    abstract:BACKGROUND AND AIMS:Muscle strength may decline with age differentially in the upper and lower limbs. This information is difficult to capture through a single measure. The present study therefore aimed to characterize the relative changes in handgrip and lower limb muscle strength with aging by expressing them as a ra...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Samuel D,Wilson K,Martin HJ,Allen R,Sayer AA,Stokes M

    更新日期:2012-06-01 00:00:00

  • A prevalence study of potentially inappropriate medications use in hospitalized Pakistani elderly.

    abstract:BACKGROUND:Inappropriate prescribing in elderly patients is a widespread health problem. It is associated with increased drug-related problems and health expenditure. AIMS:To determine the prevalence and types of potentially inappropriate medications (PIM) prescribed to elderly patients with polypharmacy and the facto...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Mazhar F,Akram S,Malhi SM,Haider N

    更新日期:2018-01-01 00:00:00

  • Changes in person-environmental fit and ADL dependence among older Swedish adults. A 10-year follow-up.

    abstract:BACKGROUND AND AIMS:In order to investigate the relation between personal functional capacity and the physical housing environment during the aging process, the aim of this study was to give a long-term description of person-environmental fit (P-E fit) problems in terms of housing accessibility and ADL dependence among...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Werngren-Elgström M,Carlsson G,Iwarsson S

    更新日期:2008-10-01 00:00:00

  • The application of the palliative prognostic index in predicting the life expectancy of patients in palliative care: a systematic review and meta-analysis.

    abstract:BACKGROUND:The palliative prognostic index (PPI) is a commonly used tool to predict the life expectancy in palliative care patients. However, there is no universal cutoff, and the accuracy of different cutoffs varies. Therefore, we conducted this meta-analysis to explore the validity and accuracy of different PPI score...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章,meta分析


    authors: Liu Y,Su L,Wang Y,Liu S,Dong B

    更新日期:2018-12-01 00:00:00

  • Related factors of cognitive impairment in community-dwelling older adults in Beijing Longitudinal Study of Aging.

    abstract:OBJECTIVES:To investigate the prevalence and related factors of cognitive impairment in community-dwelling older residents in Beijing, China. METHODS:This is a cross-sectional study. A total of 2017 older individuals aged ≥ 60 years from Beijing Longitudinal Study of Aging were included in this study. Information on d...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Han R,Tang Z,Ma L

    更新日期:2019-01-01 00:00:00

  • Validation of population-based cutoffs for low muscle mass and strength in a population of Turkish elderly adults.

    abstract:BACKGROUND:Despite differences between the studies regarding methods for estimating low muscle mass, the European Working Group on Sarcopenia in Older People (EWGSOP) recommends use of two standard deviations (SDs) below the reference sex-specific means of healthy young adults. AIMS:The aim of this study was to determ...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Ates Bulut E,Soysal P,Dokuzlar O,Kocyigit SE,Aydin AE,Yavuz I,Isik AT

    更新日期:2020-09-01 00:00:00

  • T-cell dysregulation caused by chronic antigenic stress: the role of CMV in immunosenescence?

    abstract::Dysfunctional T-cell immunity contributes to susceptibility to infectious disease in the elderly. A characteristic feature of this "immunosenescence" is the predominance of clonal expansions of CD8 cells and decreased diversity of the T-cell antigen receptor repertoire. Lifelong chronic antigenic stress commonly cause...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章,评审


    authors: Pawelec G,Gouttefangeas C

    更新日期:2006-04-01 00:00:00

  • Vitamin D receptor polymorphisms, bone ultrasound and mineral density in post-menopausal women.

    abstract:BACKGROUND AND AIMS:Bone structure, geometry and mineral content represent complex traits with a significant heritable component. However, the specific contributing genes have not been unambiguously identified. The aim of the present cross-sectional study was to analyse an association between heel ultrasound measuremen...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Zajickova K,Zofkova I,Hill M

    更新日期:2005-04-01 00:00:00

  • Impaired choice stepping in response to a visual-spatial attention demanding task among older adults at high risk of falling: a pilot study.

    abstract:BACKGROUND AND AIMS:Impairment in visual-spatial attention can cause difficulties in planning and guiding movements, leading to falls in older adults .The purpose of this study was to investigate the relationship between visual-spatial attention during movement and the risk of falling in older adults. METHODS:Thirty-s...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Uemura K,Yamada M,Nagai K,Tanaka B,Mori S

    更新日期:2012-08-01 00:00:00

  • Clinically silent idiopathic Parkinson's disease unmasked by valproate use: a brief report.

    abstract::Valproate is an important but uncommon cause of drug induced parkinsonism in the elderly. The development of symptoms after valproate onset is unpredictable, and severity of symptoms is unrelated to plasma levels. However, though the majority of cases improve after drug cessation, parkinsonian symptoms can persist and...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Athauda D,Batley R,Ellis C

    更新日期:2015-06-01 00:00:00

  • Lokomat training in vascular dementia: motor improvement and beyond!

    abstract::Vascular dementia (VaD) is a general term describing problems with reasoning, planning, judgment, memory, and other thought processes caused by brain damage from impaired blood flow to the brain. Cognitive rehabilitation and physical therapy are the mainstays of dementia treatment, although often ineffective because o...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Calabrò RS,De Luca R,Leo A,Balletta T,Marra A,Bramanti P

    更新日期:2015-12-01 00:00:00

  • Working late: the impact of work after 70 on longevity, health and function.

    abstract:BACKGROUND AND AIMS:Although many older persons choose to postpone retirement, the health consequences of this decision are still debated. This study aimed at determining the impact of continued employment on life-style, well-being, health and survival in a cohort of community-dwelling 70-year-olds. METHODS:A longitud...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Hammerman-Rozenberg R,Maaravi Y,Cohen A,Stessman J

    更新日期:2005-12-01 00:00:00

  • Relationships between adiponectin and matrix metalloproteinase-9 (MMP-9) serum levels and postoperative cognitive dysfunction in elderly patients after general anesthesia.

    abstract:OBJECTIVE:The aim of this study was to evaluate the relationships between the serum levels of adiponectin (ADP) and matrix metalloproteinase-9 (MMP-9) and postoperative cognitive dysfunction (POCD) in elderly patients after general anesthesia. METHODS:The cognitive functions of 98 elderly patients who were scheduled t...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Xie H,Huang D,Zhang S,Hu X,Guo J,Wang Z,Zhou G

    更新日期:2016-12-01 00:00:00

  • Racial variations in self-reported osteoarthritis symptom severity among veterans.

    abstract:BACKGROUND AND AIMS:This study aimed at examining factors related to osteoarthritis (OA) symptom severity in African American and Caucasian veterans (n=202). METHODS:OA symptom severity (lower extremity pain, stiffness, and physical function) was measured by the Western Ontario and McMaster Universities Osteoarthritis...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Golightly YM,Dominick KL

    更新日期:2005-08-01 00:00:00

  • Osseointegration in the elderly.

    abstract::Osseointegration is a term that refers to the formation of a direct interface between an implant and bone without intervening soft tissue. Cementless femoral fixation in total hip arthroplasty is dependent on mechanical and biological factors that affect implant stability and long-term outcome. Osteoporosis leads to m...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Piarulli G,Rossi A,Zatti G

    更新日期:2013-10-01 00:00:00

  • Depression in the elderly: new concepts and therapeutic approaches.

    abstract::Depression is one of the leading causes of suffering in the elderly, but it is often under-diagnosed and under-treated, partly due to the false belief that depression is a common aspect of aging. Depression in the elderly is frequently comorbid with medical illnesses, may often be expressed by somatic complaints, and ...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章,评审


    authors: Mecocci P,Cherubini A,Mariani E,Ruggiero C,Senin U

    更新日期:2004-06-01 00:00:00

  • Fixation-free incisional hernia repair in the elderly: our experience with a tentacle-shaped implant.

    abstract:BACKGROUND:Incisional hernia in aged patients represents a challenge even for experienced surgeons. Besides increased risk of complications due to comorbidities, mesh fixation and assuring a sufficient mesh overlap of the defect are the main issues in carrying out the repair. AIMS:In order to assure broader coverage o...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Romano G,Calò PG,Erdas E,Medas F,Gordini L,Podda F,Amato G

    更新日期:2017-02-01 00:00:00

  • Validity of the interRAI Acute Care based on test content: a multi-center study.

    abstract:BACKGROUND AND AIMS:The MDS inter- RAI Acute Care is a comprehensive geriatric assessment tool for hospitalized older persons. The aim was to examine its validity based on test content by use in daily clinical practice. METHODS:Clinical staff of multiple disciplines assessed 256 older persons (83.2±5.2 years; 60% fema...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章,多中心研究


    authors: Wellens NI,Deschodt M,Boonen S,Flamaing J,Gray L,Moons P,Milisen K

    更新日期:2011-10-01 00:00:00

  • Using the Multidimensional Prognostic Index (MPI) to improve cost-effectiveness of interventions in multimorbid frail older persons: results and final recommendations from the MPI_AGE European Project.

    abstract::MPI_AGE is a European Union co-funded research project aimed to use the Multidimensional Prognostic Index (MPI), a validated Comprehensive Geriatric Assessment (CGA)-based prognostic tool, to develop predictive rules that guide clinical and management decisions in older people in different European countries. A series...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章,评审


    authors: Cruz-Jentoft AJ,Daragjati J,Fratiglioni L,Maggi S,Mangoni AA,Mattace-Raso F,Paccalin M,Polidori MC,Topinkova E,Ferrucci L,Pilotto A,MPI_AGE Investigators.

    更新日期:2020-05-01 00:00:00

  • Stepping down backwards as a means of detecting biomechanical differences between healthy older and younger adults.

    abstract:BACKGROUND AND AIMS:Changes in sensory- motor systems that occur with age result in a decrease in postural equilibrium, which has been linked with an increased risk of falling in the elderly. Stepping down backwards from a step perturbs dynamic postural equilibrium, thus offering an opportunity to analyze the biomechan...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Michel-Pellegrino V,Hewson D,Hogrel JY,Duchêne J

    更新日期:2008-06-01 00:00:00

  • Acute effects of exergames on cognitive function of institutionalized older persons: a single-blinded, randomized and controlled pilot study.

    abstract:BACKGROUND:Improvements on balance, gait and cognition are some of the benefits of exergames. Few studies have investigated the cognitive effects of exergames in institutionalized older persons. AIMS:To assess the acute effect of a single session of exergames on cognition of institutionalized older persons. METHODS:N...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章,随机对照试验


    authors: Monteiro-Junior RS,da Silva Figueiredo LF,Maciel-Pinheiro PT,Abud ELR,Braga AEMM,Barca ML,Engedal K,Nascimento OJM,Deslandes AC,Laks J

    更新日期:2017-06-01 00:00:00