Abstract:
:Objective: To report the clinical features and treatment outcomes in immunocompetent patients with anterior segment inflammation (ASI) related to human cytomegalovirus (HCMV) depending on their ethnic origin. Material and Methods: Multicenter retrospective study of 38 patients with at least one test, either HCMV-positive PCR or GWc. Results: Features of Posner-Schlossman syndrome were observed in 50% of the eyes, Fuchs heterochromic iridocyclitis in 13% of the eyes, chronic nonspecific anterior uveitis in 21% of the eyes, and corneal endotheliitis in 18% of the eyes. PCR and GWc were positive for HCMV in 50% and 96.2% of the eyes, respectively. Glaucoma was diagnosed in 50% of eyes. Treatment was oral valganciclovir in about half of the patients. Other treatments were intravenous ganciclovir and/or ganciclovir topical ointment and/or intravitreal ganciclovir. Conclusions: No obvious association of specific clinical features with individual ethnicity could be identified. We found a high rate of glaucoma in all ethnic groups. There was a delay in diagnosis and specific treatment of HCMV in most patients.
journal_name
Ocul Immunol Inflammjournal_title
Ocular immunology and inflammationauthors
Leleu I,Jhanji V,Touhami S,Westcott M,Angi M,Titah C,Rousseau A,Hamard P,Brasnu E,Manicom T,Blumen-Ohana E,Rozenberg F,Vauloup-Fellous C,Deback C,Labetoulle M,Sahel JA,Bodaghi B,Merabet L,Kobal A,Brignole-Baudouin Fdoi
10.1080/09273948.2019.1662059subject
Has Abstractpub_date
2019-10-23 00:00:00pages
1-9eissn
0927-3948issn
1744-5078pub_type
杂志文章abstract::Recent reports have shown that dry eye in Sjögren's syndrome (SS) is associated with reactivation of Epstein-Barr virus (EBV) in lacrimal glands. However, the number of patients examined were few and it has not been determined whether dry eye in the absence of SS is also related to EBV reactivation. The authors exam...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273949409057066
更新日期:1994-01-01 00:00:00
abstract:PURPOSE:The purpose of this study was to examine 2 cases of cytomegalovirus (CMV) retinitis, occuring in 2 immunocompentent adult patients. METHODS:Case selection and literature review. RESULTS:Both patients cited significantly decreased vision despite systemic, topical, and/or local corticosteroid use. Neither patie...
journal_title:Ocular immunology and inflammation
pub_type: 信件,评审
doi:10.3109/09273948.2013.786095
更新日期:2013-08-01 00:00:00
abstract::Purpose: The purpose of the article is to describe a novel case of idiopathic central nervous system inflammatory disease with bilateral human leukocyte antigen (HLA)-B27-positive anterior uveitis. Methods/Results: A 15-year-old African American boy with bilateral HLA-B27-positive anterior uveitis controlled with topi...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2018.1449865
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:To report a case of acute retinal necrosis (ARN) occurring in the opposite eye to the ophthalmic shingles eruption. DESIGN:Case report. METHODS:Clinical examination and multimodal imaging review, including ultra-widefield photography and fluorescein angiography (FA). RESULTS:A 49-years-old man attended the U...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2020.1770298
更新日期:2020-07-09 00:00:00
abstract:PURPOSE:To determine the incidence of bacterial contamination of needles used for intravitreal injections. METHODS:Patients undergoing intravitreal injections were enrolled prospectively. No pre-injection antibiotics were administered. Following povidone-iodine irrigation, conjunctival cultures were taken and the inje...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章,多中心研究
doi:10.3109/09273948.2010.520405
更新日期:2011-02-01 00:00:00
abstract:PURPOSE:Uveitis is the most common extra-articular manifestation of juvenile idiopathic arthritis (JIA) and is associated with considerable morbidity. The aim of this study was to examine the risk factors associated with uveitis in oligoarticular JIA. METHODS:We conducted a chart review of 86 patients with oligoarticu...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2013.841495
更新日期:2014-06-01 00:00:00
abstract::Purpose: To describe tuberculous uveitis (TU) presenting as a bullous retinal detachment (RD) and to perform a comprehensive literature review on TU with similar features. Methods: Observational case report and systematic literature review. Results: An 84-year-old woman presented with bilateral granulomatous uveitis a...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2018.1485958
更新日期:2019-01-01 00:00:00
abstract::Background: Post-streptococcal uveitis is a rare ocular disease which is part of other auto-immune conditions associated with post-streptococcal syndrome. It was first mentioned in medical literature in 1991, with only a few cases published at that time. We are presenting the case of a patient with bilateral panuveiti...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2018.1501493
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:Investigate the efficacy of intravitreal adalimumab in breakthrough panuveitis in patients on systemic adalimumab for more than 3 months. METHODS:Retrospective study of patients on systemic adalimumab with breakthrough panuveitis requiring intravitreal adalimumab therapy. RESULTS:Seven eyes of four patients w...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2017.1335756
更新日期:2018-01-01 00:00:00
abstract::Intraocular tuberculosis presents a diagnostic challenge because of its protean clinical manifestations. Thus, it becomes imperative to distinguish chorioretinal inflammation due to tuberculosis from other infectious as well as non-infectious posterior uveitis since the clinical manifestations of these entities may be...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章,评审
doi:10.1080/09273948.2016.1231332
更新日期:2017-02-01 00:00:00
abstract::Immune Reconstitution Inflammatory Syndrome (IRIS) is an inflammatory syndrome in the context of immune restoration directed at a specific infectious antigen despite resolution of infection, often associated with opportunistic infections. IRIS has been reported in 30% to 35% of HIV patients who have cryptococcosis in ...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273940903003505
更新日期:2009-09-01 00:00:00
abstract:PURPOSE:To describe an unusual manifestation of sarcoidosis as a large tumor of the iris and ciliary body without any other involvement of the body. METHODS:We describe a 20-year-old female presenting with a granulomatous tumor of the right iris and ciliary body and concomitant uveitis. RESULTS:Extensive ocular and s...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/092739490500156
更新日期:2004-09-01 00:00:00
abstract::We report a case of unilateral glaucoma with falsely low intraocular pressure reading as a result of scleral thinning from anterior scleritis. ...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273940490912344
更新日期:2005-12-01 00:00:00
abstract::Potent antiretroviral therapy can result in substantial improvement in the immune function of patients with AIDS. In some patients with preexisting cytomegalovirus (CMV) retinitis, a consequence of this improved immune function is increased intraocular inflammation. This phenomenon, termed 'immune recovery uveitis', i...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章,评审
doi:10.1076/ocii.7.3.215.4010
更新日期:1999-12-01 00:00:00
abstract:PURPOSE:Primary vitreoretinal lymphomas (PVRL) pose a major diagnostic challenge, especially in the countries with a high prevalence of infectious variety of uveitis. The present study aims to report the clinical characteristics and diagnostic difficulties in patients with PVRL in an Indian Population. METHODS:Retrosp...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2016.1139731
更新日期:2017-10-01 00:00:00
abstract::Purpose: To study outcome of secondary glaucoma in pediatric uveitis patients. Methods: Retrospective analysis of records of uveitis patients ≤16 years. Results: Of 182 pediatric uveitis patients, secondary glaucoma was seen in 48 patients (75 eyes, 26.23%) with female preponderance (F:M-29:19) . JIA was the most comm...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2017.1411517
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:The aim of the present study was to evaluate retinal and choroidal thicknesses in children with familial Mediterranean fever (FMF). METHODS:Thirty patients with FMF and 28 healthy controls were included in the study. The thicknesses of the retina and choroid of each subject's right eye were measured at the fov...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2014.916309
更新日期:2014-12-01 00:00:00
abstract::Purpose: To emphasize the different manifestations of ocular involvement in Whipple disease with challenge in establishing the diagnosis as clinical, laboratory, and histological features could mimic other uveitis entities. Methods: Case reports of three patients. Results: The first patient was an African male sufferi...
journal_title:Ocular immunology and inflammation
pub_type: 信件
doi:10.1080/09273948.2018.1518461
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:To report 2 cases of branch retinal artery occlusion (BRAO) associated with Behçet disease (BD). DESIGN:Small case series. METHODS:Review of two patients' charts, fluorescein angiography, and optical coherence tomography (OCT). RESULTS:The authors report two young patients, diagnosed with BD, who developed d...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2011.582219
更新日期:2011-08-01 00:00:00
abstract:PURPOSE:To assess the retinal nerve fiber layer thickness in children with human immunodeficiency virus disease without cytomegalovirus retinitis or visual symptoms. METHODS:Thirty-eight eyes of 19 human immunodeficiency virus-positive children (group A) with visual acuity of 20/20 or better, normal color vision testi...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273940701375154
更新日期:2007-07-01 00:00:00
abstract:PURPOSE:To investigate the safety of pharmaceutically compounded syringes for intravitreal administration of anti-vascular endothelial growth factor (anti-VEGF) drugs. METHODS:Single center, retrospective chart review. From 2015 to 2019, Oslo University Hospital, Norway gradually implemented pharmaceutical compounding...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2020.1820530
更新日期:2020-10-07 00:00:00
abstract::A 45-year-old man was diagnosed with diffuse large B-cell lymphoma stage IV which was confirmed by celiac lymph node biopsy. He subsequently completed six cycles of R-CHOP chemotherapy. Six months later, he presented with panuveitis OU with positive relative afferent pupillary defect OD. OCT revealed hyper-reflective ...
journal_title:Ocular immunology and inflammation
pub_type: 信件
doi:10.1080/09273948.2020.1800050
更新日期:2020-09-24 00:00:00
abstract:PURPOSE:To identify the means by which in-vitro-generated regulatory T cells, similar to those in anterior chamber-associated immune deviation (ACAID), suppress antigen-specific T-cell responses. METHODS:T regulators (T regs), generated by stimulating ovalbumin (OVA)-specific Tcr transgenic DO11.10 T cells with OVA-pu...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273940490895317
更新日期:2004-06-01 00:00:00
abstract:OBJECTIVE:To report a case of toxic anterior uveitis probably secondary to the use of topical podophyllum. DESIGN:Case report, interventional. METHODS:The authors present a 78-year-old male with acute anterior uveitis that developed within a couple of hours of application of topical podophyllum. In vivo confocal micr...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2010.551446
更新日期:2011-04-01 00:00:00
abstract::Purpose: To investigate the prevalence of macular abnormalities in Chinese Vogt-Koyanagi-Harada (VKH) patients.Methods: Clinical characteristics, therapeutic effectiveness and visual outcome were reviewed and analyzed.Results: The most common macular abnormality was macular edema (ME), followed by macular choroidal ne...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2019.1624781
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:To describe a patient with a tolerated cilium in the anterior chamber. METHODS:A 15-year-old girl, referred with a 5-year trauma history, was examined. A cilium was noted in the anterior chamber without any inflammation during routine ophthalmological examination. RESULTS:The cilium was removed surgically and...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章,评审
doi:10.1076/ocii.11.1.73.15576
更新日期:2003-03-01 00:00:00
abstract:PURPOSE:To report the outcomes of cataract surgery in ocular cicatricial pemphigoid (OCP). SETTING:L. V. Prasad Eye Institute, Hyderabad, India. DESIGN:Retrospective, interventional case series. METHODS:Patients diagnosed with OCP who had undergone cataract surgery were included. Staging of disease, type of surgery,...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2013.819106
更新日期:2013-12-01 00:00:00
abstract::Several subjective and arbitrary grading methods are used in assessing cell and flare in uveitis. Clinicians are in need of an objective method of determining and monitoring active inflammation. We studied the correlation of changes in macular thickness between the visits and compared the change to visual acuity (VA),...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273940802702587
更新日期:2009-07-01 00:00:00
abstract::The eye is an immune-privileged site that uses specialized mechanisms to protect itself from damage and to preserve its visual acuity. Among the mechanisms that contribute to the eye's privileged existence is its ability to induce both local and peripheral tolerance to antigens that may transgress its chambers. Experi...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章,评审
doi:10.1080/09273940490912371
更新日期:2005-04-01 00:00:00
abstract:PURPOSE:To analyze the clinical features, course, management, and outcomes of tubercular (TB) uveitis in the pediatric population and assess the response to anti-tubercular therapy (ATT). METHODS:Hospital records of children (≤16 years) from a large tertiary-care institute between January 2001 and December 2015 were r...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2017.1296579
更新日期:2018-01-01 00:00:00