In vitro assembly of virus-like particles of a gammaretrovirus, the murine leukemia virus XMRV.

abstract：:The full-length sequence of a satellite RNA (sat-RNA) of Beet black scorch virus isolate X (BBSV-X) was determined. This agent is 615 nucleotides long and lacks extensive sequence homology with its helper virus or with other reported viruses. Purified virus particles contained abundant single-stranded plus-sense monom...

journal_title：Journal of virology

authors： Guo LH,Cao YH,Li DW,Niu SN,Cai ZN,Han CG,Zhai YF,Yu JL

更新日期：2005-03-01 00:00:00

abstract：:2'-5'-Oligoadenylate synthetase-like protein (OASL) is an interferon-inducible antiviral protein. Here we describe differential inhibitory activities of human OASL and the two mouse OASL homologs against respiratory syncytial virus (RSV) replication. Interestingly, nonstructural protein 1 (NS1) of RSV promoted proteas...

journal_title：Journal of virology

authors： Dhar J,Cuevas RA,Goswami R,Zhu J,Sarkar SN,Barik S

更新日期：2015-10-01 00:00:00

abstract：:Sequence analysis of the short unique (Us) segment of the bovine herpesvirus 1 (BHV-1) genome predicted that the Us open reading frame (ORF) 4 encodes a protein with homology to glycoprotein G (gG) of other alpha-herpesviruses (P. Leung-Tack, J.-C. Audonnet, and M. Riviere, Virology 199:409-421, 1994). RNA analysis sh...

journal_title：Journal of virology

authors： Keil GM,Engelhardt T,Karger A,Enz M

更新日期：1996-05-01 00:00:00

abstract：:The family Bunyaviridae is the most diversified family of RNA viruses. We describe a novel prototypic bunyavirus, tentatively named Gouléako virus, isolated from various mosquito species trapped in Côte d'Ivoire. The S segment comprised 1,087 nucleotides (nt), the M segment 3,188 nt, and the L segment 6,358 nt, consti...

journal_title：Journal of virology

authors： Marklewitz M,Handrick S,Grasse W,Kurth A,Lukashev A,Drosten C,Ellerbrok H,Leendertz FH,Pauli G,Junglen S

更新日期：2011-09-01 00:00:00

abstract：:The bovine leukemia virus (BLV) is an oncogenic retrovirus that is associated with the development of persistent lymphocytosis (PL) and lymphoma in cattle. While B lymphocytes have been shown to be the primary cellular target of BLV, recent studies suggest that some T lymphocytes and monocytes may be infected by the v...

journal_title：Journal of virology

authors： Mirsky ML,Olmstead CA,Da Y,Lewin HA

更新日期：1996-04-01 00:00:00

abstract：:Heterologous viral infections have been shown to impact the preexisting memory CD8(+)-T-cell repertoire. Bacterial superantigens are products of common human pathogenic bacteria, including staphylococci and streptococci, that are potent T-cell-stimulatory molecules. In this report, we show that exposure to staphylococ...

journal_title：Journal of virology

authors： Huang CC,Shah S,Nguyen P,Altman JD,Blackman MA

更新日期：2002-07-01 00:00:00

abstract：:We examined the population structure and genetic variation of four genomic regions within and between 30 Citrus tristeza virus (CTV) isolates from Spain and California. Our analyses showed that most isolates contained a population of sequence variants, with one being predominant. Four isolates showed two major sequenc...

journal_title：Journal of virology

authors： Rubio L,Ayllón MA,Kong P,Fernández A,Polek M,Guerri J,Moreno P,Falk BW

更新日期：2001-09-01 00:00:00

abstract：:The herpes simplex virus type 1 UL28 gene contains a 785-amino-acid open reading frame that codes for an essential protein. Studies with temperature-sensitive mutants which map to the UL28 gene indicate that the UL28 gene product (ICP18.5) is required for packaging of viral DNA and for expression of viral glycoprotein...

journal_title：Journal of virology

authors： Tengelsen LA,Pederson NE,Shaver PR,Wathen MW,Homa FL

更新日期：1993-06-01 00:00:00

abstract：:H9N2 influenza viruses are panzootic in domestic poultry in Eurasia and since 1999 have caused transient infections in humans and pigs. To investigate the zoonotic potential of H9N2 viruses, we studied the evolution of the viruses in live-poultry markets in Hong Kong in 2003. H9N2 was the most prevalent influenza viru...

journal_title：Journal of virology

authors： Choi YK,Ozaki H,Webby RJ,Webster RG,Peiris JS,Poon L,Butt C,Leung YH,Guan Y

更新日期：2004-08-01 00:00:00

abstract：:Human herpesvirus 8 (HHV-8) (also known as Kaposi's sarcoma-associated herpesvirus) encodes a novel noncoding polyadenylated nuclear (PAN) RNA (also known as T1.1 or nut-1) during the early phase of lytic replication. PAN RNA is the most abundant transcript of HHV-8, comprising 80% of total poly(A)-selected transcript...

journal_title：Journal of virology

authors： Song MJ,Brown HJ,Wu TT,Sun R

更新日期：2001-04-01 00:00:00

abstract：:We have developed a means to identify genes associated with particular aspects of virulence. By beginning with an avirulent deletion mutant of rabbitpox virus and systematically reintroducing overlapping segments of the deleted region, we have identified two regions of the viral genome associated with increased virule...

journal_title：Journal of virology

authors： Bloom DC,Edwards KM,Hager C,Moyer RW

更新日期：1991-03-01 00:00:00

abstract：:Antibodies directed to Sindbis virus (SV) envelope protein E2 are able to control virus replication in vivo and in persistently infected cultures of neurons in vitro. We investigated the mechanisms by which anti-E2 monoclonal antibody (MAb) alters virus replication by using AT3 rat prostatic carcinoma cells expressing...

journal_title：Journal of virology

authors： Després P,Griffin JW,Griffin DE

更新日期：1995-11-01 00:00:00

abstract：:Rhesus monkey rhadinovirus (RRV), a simian gamma-2 herpesvirus closely related to the Kaposi sarcoma-associated herpesvirus, replicates lytically in cultured rhesus monkey fibroblasts and establishes persistence in B cells. Overlapping cosmid clones were generated that encompass the entire 130-kilobase-pair genome of ...

journal_title：Journal of virology

authors： Bilello JP,Morgan JS,Damania B,Lang SM,Desrosiers RC

更新日期：2006-02-01 00:00:00

abstract：:Klebsiella pneumoniae MirM7 is a wild-type strain which grows as cocci at pH 7 and above and as rods at pH 6.5 and below. Cultures of this strain and an auxotrophic derivative, MirM7b, have been found to undergo spontaneous lysis after purification from possible contaminating viruses. Lysates always contained two phag...

journal_title：Journal of virology

authors： Satta G,Pruzzo C,Debbia E,Fontana R

更新日期：1978-12-01 00:00:00

abstract：:The agent(s) responsible for sporadic non-A, non-B hepatitis in humans was serially transmitted in rhesus monkeys by intravenous inoculation of the stool extract from a patient. A novel agent called HFV (hepatitis French [origin] virus) was present as 27- to 37-nm particles in the infectious stool extract. Hepatopathi...

journal_title：Journal of virology

authors： Deka N,Sharma MD,Mukerjee R

更新日期：1994-12-01 00:00:00

abstract：:Using synthetic peptides, we characterized the B-lymphocyte (antibody) and T-lymphocyte (proliferation) responses to an immunodominant epitope of human immunodeficiency virus type 1 (HIV-1) located near the amino-terminal end of the transmembrane glycoprotein (env amino acids 598 to 609). Both immunoglobulin M (IgM) a...

journal_title：Journal of virology

authors： Schrier RD,Gnann JW Jr,Langlois AJ,Shriver K,Nelson JA,Oldstone MB

更新日期：1988-08-01 00:00:00

abstract：:Superinfection of Corynebacterium diphtheriae C7(beta) by heteroimmune phage gamma is productive, whereas superinfection by gamma-bin mutants is for the most part nonproductive. Exclusion of gamma-bin phage occurred after its DNA had penetrated and was partially expressed in the heteroimmune lysogen. All of the infect...

journal_title：Journal of virology

authors： Groman NB,Rabin M

更新日期：1980-11-01 00:00:00

abstract：:Accumulation of the interferon-stimulated gene 15 (ISG15) protein product, which is reversibly conjugated to numerous polypeptide targets, impacts the proteome and physiology of uninfected and infected cells. While many viruses, including human cytomegalovirus (HCMV), blunt host antiviral defenses by limiting ISG expr...

journal_title：Journal of virology

authors： Bianco C,Mohr I

更新日期：2017-04-13 00:00:00

abstract：:Spatial variation in the epidemiological patterns of successive waves of pandemic influenza virus in humans has been documented throughout the 20th century but never understood at a molecular level. However, the unprecedented intensity of sampling and whole-genome sequencing of the H1N1/09 pandemic virus now makes suc...

journal_title：Journal of virology

authors： Nelson MI,Tan Y,Ghedin E,Wentworth DE,St George K,Edelman L,Beck ET,Fan J,Lam TT,Kumar S,Spiro DJ,Simonsen L,Viboud C,Holmes EC,Henrickson KJ,Musser JM

更新日期：2011-01-01 00:00:00

abstract：:A versatile green fluorescent protein (GFP) expression cassette containing the replication origins of the monopartite begomovirus Tomato yellow leaf curl Sardinia virus (TYLCSV) is described. Transgenic Nicotiana benthamiana plants containing one copy of the cassette stably integrated into their genome were superinfec...

journal_title：Journal of virology

authors： Morilla G,Castillo AG,Preiss W,Jeske H,Bejarano ER

更新日期：2006-04-01 00:00:00

abstract：:Differential effect of various metabolic inhibitors on the development of hemadsorption activity and virus formation in cells infected with Newcastle disease virus (NDV) was investigated. It was found that, in BHK-21 cells infected with NDV, cycloheximide did not prevent the development of hemadsorption activity, wher...

journal_title：Journal of virology

authors： Nagai Y

更新日期：1973-04-01 00:00:00

abstract：:Using gel mobility assays, we have detected two proteins that bind in the U3 region of the 1731 retrotransposon long terminal repeats (between positions -110 and -73) in nuclear extracts from Drosophila melanogaster cultured cells. The first one binds double-stranded DNA, whereas the other binds the mRNA-like strand i...

journal_title：Journal of virology

authors： Fourcade-Peronnet F,Codani-Simonart S,Best-Belpomme M

更新日期：1992-03-01 00:00:00

abstract：:The HXLF (HindIII-X left reading frame) gene family is a group of five genes that share one or two regions of homology and are arranged in tandem within the short unique component of the human cytomegalovirus genome (K. Weston and B.G. Barrell, J. Mol. Biol. 192:177-208, 1986). These genes were cloned into an SP6 expr...

journal_title：Journal of virology

authors： Gretch DR,Kari B,Gehrz RC,Stinski MF

更新日期：1988-06-01 00:00:00

abstract：:Latent Epstein-Barr virus (EBV) infection is associated with several lymphoproliferative disorders, including posttransplant lymphoma, Hodgkin's disease, and Burkitt's lymphoma, as well as nasopharyngeal carcinoma (NPC). Twenty-nine microRNAs (miRNAs) have been identified that are transcribed during latent infection f...

journal_title：Journal of virology

authors： Edwards RH,Marquitz AR,Raab-Traub N

更新日期：2008-09-01 00:00:00

abstract：:Ebola virus (EBOV) causes a lethal hemorrhagic fever for which there is no approved effective treatment or prevention strategy. EBOV VP35 is a virulence factor that blocks innate antiviral host responses, including the induction of and response to alpha/beta interferon. VP35 is also an RNA silencing suppressor (RSS). ...

journal_title：Journal of virology

authors： Zhu Y,Cherukuri NC,Jackel JN,Wu Z,Crary M,Buckley KJ,Bisaro DM,Parris DS

更新日期：2012-03-01 00:00:00

abstract：:Human CD4(+) T-helper 1 cell responses to Epstein-Barr virus (EBV) infection are likely to be important in the maintenance of virus-specific CD8(+) memory and/or as antiviral effectors in their own right. The present work has used overlapping peptides as stimulators of gamma interferon release (i) to identify CD4(+) e...

journal_title：Journal of virology

authors： Leen A,Meij P,Redchenko I,Middeldorp J,Bloemena E,Rickinson A,Blake N

更新日期：2001-09-01 00:00:00

abstract：:Rhinoviruses (RV) are the major cause of acute exacerbations of asthma and chronic obstructive pulmonary disease (COPD). Rhinoviruses have been shown to activate macrophages, but rhinovirus replication in macrophages has not been reported. Tumor necrosis factor alpha (TNF-alpha) is implicated in the pathogenesis of ac...

journal_title：Journal of virology

authors： Laza-Stanca V,Stanciu LA,Message SD,Edwards MR,Gern JE,Johnston SL

更新日期：2006-08-01 00:00:00

abstract：:The nucleotide sequence of the src gene and flanking regions of the Schmidt-Ruppin strain of Rous sarcoma virus (SR-A) was determined. The src region of SR-A was very homologous to that of recovered avian sarcoma virus (rASV1441), with only 17 differences among 1,578 nucleotides. The size of the predicted protein was ...

journal_title：Journal of virology

authors： Takeya T,Hanafusa H

更新日期：1982-10-01 00:00:00

abstract：:The reovirus core particle is a molecular machine that mediates synthesis, capping, and export of the viral plus strand RNA transcripts. Its assembly and structure-function relationships remain to be well understood. Following the lead of previous studies with other Reoviridae family members, most notably orbiviruses ...

journal_title：Journal of virology

authors： Kim J,Zhang X,Centonze VE,Bowman VD,Noble S,Baker TS,Nibert ML

更新日期：2002-12-01 00:00:00

abstract：UNLABELLED:Capsid-associated tegument proteins have been identified in alpha- and betaherpesviruses to play an essential role in viral DNA packaging. Whether and how such tegument proteins exist in gammaherpesviruses have been mysteries. Here, we report a 6-Å-resolution cryo-electron microscopy (cryo-EM) structure of K...

journal_title：Journal of virology

authors： Dai X,Gong D,Wu TT,Sun R,Zhou ZH

更新日期：2014-11-01 00:00:00