Epstein-Barr virus BART microRNAs are produced from a large intron prior to splicing.

abstract：:A more complete assessment of ovine prion strain diversity will be achieved by complementing biological strain typing in conventional and ovine PrP transgenic mice with a biochemical analysis of the resultant PrPSc. This will provide a correlation between ovine prion strain phenotype and the molecular nature of differ...

journal_title：Journal of virology

authors： Thackray AM,Hopkins L,Spiropoulos J,Bujdoso R

更新日期：2008-11-01 00:00:00

abstract：:The XC rat cell line was found to support the replication of a strain of the Moloney murine sarcoma-leukemia virus. In growth curve experiments cytopathology was paralleled by the production of murine sarcoma virus and leukemia virus progeny having the biologic, antigenic, and biophysical properties of the infecting v...

journal_title：Journal of virology

authors： Trowbridge ST,Benyesh-Melnick M,Biswal N

更新日期：1973-01-01 00:00:00

abstract：:The successful use of a dendrimeric peptide to protect pigs against challenge with foot-and-mouth disease virus (FMDV), which causes the most devastating animal disease worldwide, is described. Animals were immunized intramuscularly with a peptide containing one copy of a FMDV T-cell epitope and branching out into fou...

journal_title：Journal of virology

authors： Cubillos C,de la Torre BG,Jakab A,Clementi G,Borrás E,Bárcena J,Andreu D,Sobrino F,Blanco E

更新日期：2008-07-01 00:00:00

abstract：:Avian erythroblastosis virus (AEV) RNA rescued from nonproducer cells by superinfection with a helper virus is translated into three polypeptides in the messenger-dependent rabbit reticulocyte lysate. A 75,000 molecular weight polypeptide (P75AEV) is synthesized from 28S RNA and is encoded by the 5' section of the AEV...

journal_title：Journal of virology

authors： Pawson T,Martin GS

更新日期：1980-04-01 00:00:00

abstract：:Hepatitis delta antigen (HDAg) is the only known protein of hepatitis delta virus and was previously shown to localize in the nucleoplasm of infected liver cells. In this study, nuclear localization signals of HDAg were defined by expressing various domains of the antigen in both hepatic and nonhepatic cells as beta-g...

journal_title：Journal of virology

authors： Chang MF,Chang SC,Chang CI,Wu K,Kang HY

更新日期：1992-10-01 00:00:00

abstract：:The human immunodeficiency virus (HIV) integrase protein (IN) catalyzes two reactions required to integrate HIV DNA into the human genome: 3' processing of the viral DNA ends and integration. IN has three domains, the N-terminal zinc-binding domain, the catalytic core, and the C-terminal SH3 domain. Previously, it was...

journal_title：Journal of virology

authors： van den Ent FM,Vos A,Plasterk RH

更新日期：1999-04-01 00:00:00

abstract：:Human immunodeficiency virus type 1 (HIV-1) vpr inhibits the replication of tumor cell lines and peripheral blood mononuclear cells. Here it is demonstrated that expression of vpr, either in the context of a provirus or from an independent genetic element, induces a discrete cell cycle arrest, with cells containing 4N...

journal_title：Journal of virology

authors： Re F,Braaten D,Franke EK,Luban J

更新日期：1995-11-01 00:00:00

abstract：:Although hepatitis A virus (HAV) is typically transmitted by the fecal-oral route, little is known of its interactions with cells of the gastrointestinal tract. We studied the replication of HAV in polarized cultures of Caco-2 cells, a human cell line which retains many differentiated functions of small intestinal epi...

journal_title：Journal of virology

authors： Blank CA,Anderson DA,Beard M,Lemon SM

更新日期：2000-07-01 00:00:00

abstract：UNLABELLED:Despite encoding multiple viral proteins that modulate the retinoblastoma (Rb) protein in a manner classically defined as inactivation, human cytomegalovirus (HCMV) requires the presence of the Rb protein to replicate efficiently. In uninfected cells, Rb controls numerous pathways that the virus also command...

journal_title：Journal of virology

authors： VanDeusen HR,Kalejta RF

更新日期：2015-12-01 00:00:00

abstract：:The E3 complex transcription unit of adenovirus encodes four major mRNAs (a, c, f, and h) and two minor (d and e) mRNAs with overlapping exons, alternative splice sites, and two polyadenylation sites, termed E3A (upstream) and E3B (downstream). mRNAs a and d use the E3A polyadenylation site, and mRNAs c, e, f, and h u...

journal_title：Journal of virology

authors： Brady HA,Scaria A,Wold WS

更新日期：1992-10-01 00:00:00

abstract：:We have evaluated the potential of conferring protective immunity to herpes simplex virus type 2 (HSV-2) by selectively inducing an HSV-specific CD8(+) cytotoxic T-lymphocyte (CTL) response directed against a single major histocompatibility complex class I-restricted CTL recognition epitope. We generated a recombinant...

journal_title：Journal of virology

authors： Blaney JE Jr,Nobusawa E,Brehm MA,Bonneau RH,Mylin LM,Fu TM,Kawaoka Y,Tevethia SS

更新日期：1998-12-01 00:00:00

abstract：:Vesicular stomatitis virus (VSV) has served for several decades as the prototype rhabdovirus and a model RNA virus. Extensive studies upheld the original view of VSV genetics with simply five genes (N, P, M, G, and L), each encoding a single unique protein. We now report the first unambiguous demonstration of the exis...

journal_title：Journal of virology

authors： Spiropoulou CF,Nichol ST

更新日期：1993-06-01 00:00:00

abstract：:Preferential integration into transcriptionally active regions of genomes has been observed for retroviral vectors based on gamma-retroviruses and lentiviruses. However, differences in the integration site preferences were detected, which might be explained by differences in viral components of the preintegration comp...

journal_title：Journal of virology

authors： Monse H,Laufs S,Kuate S,Zeller WJ,Fruehauf S,Uberla K

更新日期：2006-08-01 00:00:00

abstract：:Hemagglutinin (HA) of influenza virus must be activated by proteolysis before the virus can become infectious. Previous studies indicated that HA cleavage is driven by membrane-bound or extracellular serine proteases in the respiratory tract. However, there is still uncertainty as to which proteases are critical for a...

journal_title：Journal of virology

authors： Magnen M,Gueugnon F,Guillon A,Baranek T,Thibault VC,Petit-Courty A,de Veer SJ,Harris J,Humbles AA,Si-Tahar M,Courty Y

更新日期：2017-07-27 00:00:00

abstract：:Our previous studies showed that establishment of murine cytomegalovirus (MCMV) latency in vivo is associated with repression of immediate-early gene expression, deacetylation of histones bound to the major immediate-early promoter (MIEP), changes in patterns of methylation of histones, and recruitment of cellular rep...

journal_title：Journal of virology

authors： Liu XF,Yan S,Abecassis M,Hummel M

更新日期：2010-04-01 00:00:00

abstract：:The Epstein-Barr virus oriP, when examined with the use of in vitro nucleosome reconstitution, was found to exhibit a partial sparing of nucleosome assembly within the 3' dyad. Analysis of the homologous region containing the origin of replication of herpesvirus papio disclosed that sparing of nucleosome assembly was ...

journal_title：Journal of virology

authors： Sexton CJ,Pagano JS

更新日期：1989-12-01 00:00:00

abstract：:The papillomavirus E2 protein is a critical viral regulatory protein with transcription, DNA replication, and genome maintenance functions. We have previously identified the cellular bromodomain protein Brd4 as a major E2-interacting protein and established that it participates in tethering bovine papillomavirus type ...

journal_title：Journal of virology

authors： Schweiger MR,Ottinger M,You J,Howley PM

更新日期：2007-09-01 00:00:00

abstract：:A detailed comparison of the gp70 proteins of cloned ecotropic Friend murine leukemia virus (FLV) and dual-tropic Friend mink focus-forming virus (FrMCF) was performed by analyzing the structural and immunological properties of amino- and carboxy-terminal domains of these molecules generated upon controlled trypsiniza...

journal_title：Journal of virology

authors： Pinter A,Honnen WJ

更新日期：1984-02-01 00:00:00

abstract：:Sequences and structures within the terminal genomic regions of plus-strand RNA viruses are targets for the binding of host proteins that modulate functions such as translation, RNA replication, and encapsidation. Using murine norovirus 1 (MNV-1), we describe the presence of long-range RNA-RNA interactions that were s...

journal_title：Journal of virology

authors： López-Manríquez E,Vashist S,Ureña L,Goodfellow I,Chavez P,Mora-Heredia JE,Cancio-Lonches C,Garrido E,Gutiérrez-Escolano AL

更新日期：2013-11-01 00:00:00

abstract：UNLABELLED:Human cytomegalovirus (HCMV) is a major cause of morbidity and mortality in transplant patients and is the leading viral cause of birth defects after congenital infection. HCMV infection relies on the recognition of cell-specific receptors by one of the viral envelope glycoprotein complexes. Either the gH/gL...

journal_title：Journal of virology

authors： Caló S,Cortese M,Ciferri C,Bruno L,Gerrein R,Benucci B,Monda G,Gentile M,Kessler T,Uematsu Y,Maione D,Lilja AE,Carfí A,Merola M

更新日期：2016-04-29 00:00:00

abstract：:Molluscum contagiosum virus (MCV), a member of the human poxvirus family, encodes the MC159 protein that inhibits Fas-, tumor necrosis factor (TNF)-, and TNF-related apoptosis-inducing ligant (TRAIL)-induced apoptosis. We used site-directed mutagenesis to change charged or hydrophobic amino acid residues to alanines t...

journal_title：Journal of virology

authors： Garvey TL,Bertin J,Siegel RM,Wang GH,Lenardo MJ,Cohen JI

更新日期：2002-01-01 00:00:00

abstract：:Two foot-and-mouth disease virus (FMDV) genome sequences have been determined for isolates collected from recent field outbreaks in North Africa (Egypt) and the Middle East (Palestinian Autonomous Territories). These data represent the first examples of complete genomic sequences for the FMDV SAT 2 topotype VII, which...

journal_title：Journal of virology

authors： Valdazo-González B,Knowles NJ,Hammond J,King DP

更新日期：2012-08-01 00:00:00

abstract：:The paramyxoviral family contains many medically important viruses, including measles virus, mumps virus, parainfluenza viruses, respiratory syncytial virus, human metapneumovirus, and the deadly zoonotic henipaviruses Hendra and Nipah virus (NiV). To both enter host cells and spread from cell to cell within infected ...

journal_title：Journal of virology

authors： Stone JA,Vemulapati BM,Bradel-Tretheway B,Aguilar HC

更新日期：2016-11-14 00:00:00

abstract：:The complete nucleotide sequences of the vesicular stomatitis virus mRNA's encoding the glycoprotein (G) and the matrix protein (M) have been determined from cDNA clones that contain the complete coding sequences from each mRNA. The G protein mRNA is 1,665 nucleotides long, excluding polyadenylic acid, and encodes a p...

journal_title：Journal of virology

authors： Rose JK,Gallione CJ

更新日期：1981-08-01 00:00:00

abstract：:F111 rat cells transformed by simian virus 40 mutant tsA1499 are cold sensitive for the expression of transformation. Yet, unlike F111 cells transformed by tsA58, they do not lose the ability to stabilize the transformation-associated host cell protein p53 at the temperature at which transformation is extinguished. ...

journal_title：Journal of virology

authors： Bouck N,Fikes J,Rundell MK

更新日期：1984-03-01 00:00:00

abstract：:The mucosal adjuvant effect of synthetic double-stranded RNA polyriboinosinic polyribocytidylic acid [poly(I:C)] against influenza virus was examined under intranasal coadministration with inactivated hemagglutinin (HA) vaccine in BALB/c mice and was shown to have a protective effect against both nasal-restricted infe...

journal_title：Journal of virology

authors： Ichinohe T,Watanabe I,Ito S,Fujii H,Moriyama M,Tamura S,Takahashi H,Sawa H,Chiba J,Kurata T,Sata T,Hasegawa H

更新日期：2005-03-01 00:00:00

abstract：:Interactions between viruses and the host antibody immune response are critical in the development and control of disease, and antibodies are also known to interfere with the efficacy of viral vector-based gene delivery. The adeno-associated viruses (AAVs) being developed as vectors for corrective human gene delivery ...

journal_title：Journal of virology

authors： Gurda BL,DiMattia MA,Miller EB,Bennett A,McKenna R,Weichert WS,Nelson CD,Chen WJ,Muzyczka N,Olson NH,Sinkovits RS,Chiorini JA,Zolotutkhin S,Kozyreva OG,Samulski RJ,Baker TS,Parrish CR,Agbandje-McKenna M

更新日期：2013-08-01 00:00:00

abstract：:Herpes simplex virus type 1 (HSV-1) DNA and RNA have been detected in peripheral nervous system (PNS) and central nervous system (CNS) tissues of latently infected mice. However, explant methods are successful in reactivating HSV-1 only from latently infected PNS tissues. In this report, latent herpesvirus infections ...

journal_title：Journal of virology

authors： Deatly AM,Spivack JG,Lavi E,O'Boyle DR 2nd,Fraser NW

更新日期：1988-03-01 00:00:00

abstract：:Spumaviruses, or foamy viruses, express Gag proteins that are incompletely processed by the viral protease in cell cultures. To delineate the proteolytic cleavage sites between potential Gag subdomains, recombinant human spumaretrovirus (HSRV) Gag proteins of different lengths were expressed, purified by affinity chro...

journal_title：Journal of virology

authors： Pfrepper KI,Löchelt M,Rackwitz HR,Schnölzer M,Heid H,Flügel RM

更新日期：1999-09-01 00:00:00

abstract：:Expression of the papillomavirus E4 protein correlates with the onset of viral DNA amplification. Using a mutant cottontail rabbit papillomavirus (CRPV) genome incapable of expressing the viral E4 protein, we have shown that E4 is required for the productive stage of the CRPV life cycle in New Zealand White and cotton...

journal_title：Journal of virology

authors： Peh WL,Brandsma JL,Christensen ND,Cladel NM,Wu X,Doorbar J

更新日期：2004-02-01 00:00:00