The effects of exercise on cigarette cravings and brain activation in response to smoking-related images.

abstract：RATIONALE:The neuronal actions of methamphetamine (MA) include an increase in extracellular levels of monoamines, presumably via reverse transport involving the monoamine transporters. This action is thought to play an important role in the effects of MA. Therefore, in the present experiment, it was hypothesized that a...

journal_title：Psychopharmacology

authors： Ranaldi R,Anderson KG,Carroll FI,Woolverton WL

更新日期：2000-12-01 00:00:00

abstract：:Efforts to find a correlation between serum levels of chlorpromazine (CPZ) and clinical effect have been rather unsuccessful, which could be due to fluctuations of CPZ and CPZ metabolite levels during treatment, the complicated metabolism of CPZ, or to varying degrees of protein binding. Using a mass fragmentographic ...

journal_title：Psychopharmacology

authors： Wode-Helgodt B,Alfredsson G

更新日期：1981-01-01 00:00:00

abstract：:Established social groups of talapoin monkeys show rank-related differences in aggressive, social and sexual behaviours and visual monitoring, as well as in endocrine and monoamine profiles. Here we describe the effects on these variables of an "anxiogenic drug", beta-carboline carboxylic acid ethyl ester (beta-CCE), ...

journal_title：Psychopharmacology

authors： Vellucci SV,Herbert J,Keverne EB

更新日期：1986-01-01 00:00:00

abstract：:The four homoeopathic drugs, Gelsemium, Cannabis Indica, Graphites and Agaricus Muscarius, administered orally in 30th and 200th potencies on white rats, enhanced restraint-induced catalepsy in a similar manner to the two standard drugs pilocarpine and haloperidol (IP injection at 5 mg/kg). All the drugs tested differ...

journal_title：Psychopharmacology

authors： Sukul NC,Bala SK,Bhattacharyya B

更新日期：1986-01-01 00:00:00

abstract：RATIONALE:Ketamine, a well-known general dissociative anesthetic agent that is a non-competitive antagonist of the N-methyl-D-aspartate receptor, perturbs the perception of elapsed time and the expectation of upcoming events. OBJECTIVE:The objective of this study was to determine the influence of ketamine on temporal ...

journal_title：Psychopharmacology

authors： Brulé S,Herlin B,Pouget P,Missal M

更新日期：2021-02-01 00:00:00

abstract：RATIONALE:Relapse to smoking is often precipitated by stress, yet little is known about the effects of nicotine withdrawal on responses to acute stress, or whether nicotine replacement reverses withdrawal-induced changes in stress response. OBJECTIVES:The aim of the present study is to use an effective social stressor...

journal_title：Psychopharmacology

authors： Wardle MC,Munafò MR,de Wit H

更新日期：2011-11-01 00:00:00

abstract：:Recent work with humans and animals has suggested that the cholinergic system plays an important role in the active control of attention. This study was designed to investigate the effects of scopolamine upon subjects' ability to utilize knowledge of the spatial probability bias in a display in the detection of briefl...

journal_title：Psychopharmacology

authors： Dunne MP,Hartley LR

更新日期：1986-01-01 00:00:00

abstract：RATIONALE:Observing responses bring sensory receptors into contact with environmental stimuli. In the observing-response procedure, periods in which an operant response (e.g. pressing a lever) is reinforced by drug deliveries alternate with periods in which this response is never reinforced (i.e. extinction). These alt...

journal_title：Psychopharmacology

authors： Shahan TA

更新日期：2003-05-01 00:00:00

abstract：:The development of tolerance to the behavioral and biochemical effects of ethanol was studied. Rats were made tolerant to ethanol by the administration of daily ethanol injections (3 g/kg, IP) for 7 and 28 days. Tolerance developed both to the behavioral (hypothermic, sedative) and biochemical (accumulation of dopamin...

journal_title：Psychopharmacology

authors： Liljequist S,Ekman A,Snape B,Söderpalm B,Engel JA

更新日期：1990-01-01 00:00:00

abstract：RATIONALE:Exposure to extreme stress has been suggested to produce long-term, detrimental alterations in the hypothalamic-pituitary-adrenal (HPA) axis leading to the development of mental disorders such as depression. Therefore, compounds that block the effects of stress hormones were investigated as potential therapeu...

journal_title：Psychopharmacology

authors： Jutkiewicz EM,Wood SK,Houshyar H,Hsin LW,Rice KC,Woods JH

更新日期：2005-07-01 00:00:00

abstract：:Serotonin is a neurotransmitter that is widely distributed throughout the central nervous system. The role of serotonin in schizophrenia is still unclear. Postmortem studies of serotonin receptor subtypes in schizophrenia have been inconclusive for the most part. The most promising findings involve a reduction in 5-HT...

journal_title：Psychopharmacology

authors： Ohuoha DC,Hyde TM,Kleinman JE

更新日期：1993-01-01 00:00:00

abstract：:Food reward has been associated with activation of noradrenergic mechanisms in the brain. Using rats trained to press a lever for food reward, we have investigated the effects of 6-hydroxydopamine lesions, which severly depleted hypothalamic noradrenaline, on the willingness of the rats to press the lever for food rew...

journal_title：Psychopharmacology

authors： Kruk ZL,Millar J

更新日期：1979-06-28 00:00:00

abstract：:The peripheral BDZ receptor ligand Ro 5-4864 was administered to rabbits in doses ranging from 0.2 to 7 mg/kg IV. Changes in electrocortical activity appeared within 1 min after administration, characterized by trains of slow waves in the posterior sensorimotor and optic cortices (0.6-2 mg/kg) and by grand mal seizure...

journal_title：Psychopharmacology

authors： Massotti M,Lucantoni D

更新日期：1986-01-01 00:00:00

abstract：:Recent studies suggest that glucose enhances memory in rodents and humans. The present experiment investigated the effects of glucose on memory performance and blood glucose changes in young adults (19-25 years). Subjects ingested (300 ml beverage) three doses of glucose (0, 30, 100 g) in a random, double-blind, tripl...

journal_title：Psychopharmacology

authors： Azari NP

更新日期：1991-01-01 00:00:00

abstract：RATIONALE:Obsessive-compulsive disorder (OCD) gradually emerges and reaches clinical significance during early adulthood. Whether a predisposition for OCD manifests as binge eating disorder earlier during adolescence is proposed. OBJECTIVES:To further characterize how OCD-like behaviors increase across maturation and ...

journal_title：Psychopharmacology

authors： Freund N,Thompson BS,Norman KJ,Einhorn P,Andersen SL

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Rats reared in social isolation exhibit various cognitive and behavioural abnormalities in adulthood. However, impulsivity following this treatment still remains unclear, especially in response to medications used in attention deficit hyperactivity disorder, such as amphetamine. METHODS:Using an isolation-r...

journal_title：Psychopharmacology

authors： Liu YP,Wilkinson LS,Robbins TW

更新日期：2017-05-01 00:00:00

abstract：:Preclinical studies suggest that acoustic startle amplitude is increased during ethanol withdrawal. The current study evaluated the effects of intravenous infusion of the alpha 2-adrenergic antagonist, yohimbine (0.4 mg/kg), the serotonin partial agonist m-chlorophenylpiperazine (mCPP, 0.1 mg/kg), and placebo administ...

journal_title：Psychopharmacology

authors： Krystal JH,Webb E,Grillon C,Cooney N,Casal L,Morgan CA 3rd,Southwick SM,Davis M,Charney DS

更新日期：1997-06-01 00:00:00

abstract：RATIONALE:Each year, over 300,000 individuals in the USA enter treatment for cannabis use disorder (CUD). The development of effective pharmacotherapy for CUD is a priority. OBJECTIVE:This placebo-controlled study examined the effects of zolpidem alone and in combination with nabilone on cannabis withdrawal and a labo...

journal_title：Psychopharmacology

authors： Herrmann ES,Cooper ZD,Bedi G,Ramesh D,Reed SC,Comer SD,Foltin RW,Haney M

更新日期：2016-07-01 00:00:00

abstract：:In mice that were scored for the length of time they remained immobile in awkward postures (cataleptic) on an inclined wire grid, a large IP dose of pilocarpine (80 mg/kg) caused a clear catalepsy, which was prevented by both dopamine agonists that were tested, apomorphine (4 or 8 mg/kg, IP) and bromocriptine (8 mg/kg...

journal_title：Psychopharmacology

authors： Klemm WR

更新日期：1985-01-01 00:00:00

abstract：:A recent study from our laboratory has demonstrated that C57BL/6 male mice that are chronically injected with nicotine develop a profound tolerance to nicotine that is not associated with changes in brain nicotinic receptors. We have proposed that alterations in the secretion of corticosterone (CCS) may regulate toler...

journal_title：Psychopharmacology

authors： Grun EA,Pauly JR,Collins AC

更新日期：1992-01-01 00:00:00

abstract：:The relationship between each of two pharmacologic effects (tachycardia and psychological "high") of delta-9-tetrahydrocannabinol (THC) and plasma THC concentration was investigated in three male and three female experienced marihuana smokers. Each subject smoked 1% THC cigarette on two occasions separated by 2 h. Hea...

journal_title：Psychopharmacology

authors： Cocchetto DM,Owens SM,Perez-Reyes M,DiGuiseppi S,Miller LL

更新日期：1981-01-01 00:00:00

abstract：RATIONALE:The influence of the main dopaminergic brain regions controlling copulation, the medial preoptic area (mPOA) and the nucleus accumbens (NAcc), on male rat sexual behavior expression has not been fully established. OBJECTIVE:This work analyzes the sexual effects of dopamine (DA) receptor activation in the mPO...

journal_title：Psychopharmacology

authors： Guadarrama-Bazante IL,Rodríguez-Manzo G

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Traumatic events are associated with alcohol use problems with increased alcohol craving as a potential mediator. There is still a lack of knowledge regarding the causal nature of this association and its underlying mechanisms. This study investigated the effects of acute trauma exposure on alcohol craving i...

journal_title：Psychopharmacology

authors： Trautmann S,Kräplin A,Dieterich R,Richter J,Muehlhan M

更新日期：2018-10-01 00:00:00

abstract：RATIONALE:Stressful life events are suggested to contribute to the development of various pathologies, such as cardiovascular disorders, whose etiopathogenesis is highly associated with elevated levels of serum amyloid A (SAA) proteins. SAA synthesis in the liver is regulated by a complex network of cytokines acting in...

journal_title：Psychopharmacology

authors： Konstandi M,Sotiropoulos I,Matsubara T,Malliou F,Katsogridaki A,Andriopoulou CE,Gonzalez FJ

更新日期：2019-06-01 00:00:00

abstract：:The effects of dopamine agonists on self-stimulation are a matter of considerable dispute. Apomorphine has variously been reported to inhibit, have no effect on, or to facilitate lever-press self-stimulation. To investigate the possibility that these discrepancies may reflect peculiarities of the lever-press test situ...

journal_title：Psychopharmacology

authors： Atrens DM,Becker FT,Hunt GE

更新日期：1980-01-01 00:00:00

abstract：:A combined analysis of data from 11 controlled studies of loxapine versus either chlorpromazine or trifluoperazine in acute schizophrenia (5 studies) and chronic schizophrenia (6 studies) showed statistically significant superiority of loxapine on several items and factors of standardized psychiatric rating scales. Up...

journal_title：Psychopharmacology

authors： Bishop MP,Simpson GM,Dunnett CW,Kiltie H

更新日期：1977-01-31 00:00:00

abstract：:In order to validate a new animal model predictive of the profile of antiepileptic drugs, we studied the antagonism by standard antiepileptics of the EEG modifications induced by low-speed IV infusion of pentylenetetrazol (PTZ) in rats. The activity of the drugs was measured by their effects on temporal characteristic...

journal_title：Psychopharmacology

authors： Santucci V,Fournier M,Keane P,Simiand J,Michaud JC,Morre M,Biziere K

更新日期：1985-01-01 00:00:00

abstract：RATIONALE:Several halogenated analogs of benztropine (BZT) have previously been characterized as potent DA uptake inhibitors with behavioral profiles that indicate diminished psychomotor stimulant effects relative to cocaine. In a previous study using a fixed-ratio 10 schedule, two chloro-analogs (3'-Cl-BZT and 4'-Cl-B...

journal_title：Psychopharmacology

authors： Woolverton WL,Hecht GS,Agoston GE,Katz JL,Newman AH

更新日期：2001-04-01 00:00:00

abstract：RATIONALE:Glucocorticoids have been shown to affect declarative memory, an explicit form of memory for facts and events operated by medial temporal lobe structures. Recent neuroimaging data suggest that the medial temporal lobe (including the hippocampus) is also active in implicit sequence learning. OBJECTIVES:The ai...

journal_title：Psychopharmacology

authors： Römer S,Schulz A,Richter S,Lass-Hennemann J,Schächinger H

更新日期：2011-05-01 00:00:00

abstract：RATIONALE:Cortical gamma-aminobutyric acid (GABA)ergic neurons contribute to the orchestration of pyramidal neuron population firing as follows: (1) by releasing GABA on GABA(A) and GABA(B) receptors, (2) by releasing reelin in the proximity of integrin receptors located on cortical pyramidal neuron dendritic spines, a...

journal_title：Psychopharmacology

authors： Guidotti A,Auta J,Davis JM,Dong E,Grayson DR,Veldic M,Zhang X,Costa E

更新日期：2005-07-01 00:00:00